Can CBD toothpaste help promote dental health and whiten teeth?

Plaque build-up around the teeth and gum line creates a breeding ground for bacteria to thrive. Failure to eliminate the bacteria can lead to gingivitis.

Gingivitis is a mild form of periodontal (gum) disease that causes irritation, redness and inflammation (swelling) of the gingiva, the gum line around the base of teeth (1).

When left untreated, gingivitis can lead to periodontitis, an oral disease which causes the gums to break down and teeth to become loose, possibly requiring extractions.

Why Use CBD Toothpaste?

Great oral health is a precedent for excellent overall health. Brushing and flossing help prevent the accumulation of plaque. However, not all kinds of toothpaste are created equal. 

The good news is that CBD has been added to an assortment of miscellaneous products, with some CBD products targeting oral health.
There are CBD toothpicks, CBD mouthwash, CBD toothpaste, and CBD oil applied directly into the mouth. 

Toothpaste infused with CBD may be an excellent supplement to oral care management and hygiene. 

There are variants of CBD toothpaste that contain other ingredients, such as activated charcoal to whiten teeth, xylitol to help prevent tooth decay and dry mouth, and coconut oil to fight bacteria and freshen breath. 

The combination of all the unique oral health benefits of these active ingredients and the potential therapeutic effects of a full-spectrum CBD hemp oil-infused toothpaste makes for a powerful tool to promote and maintain healthy teeth and gums.

The Science Behind Using CBD Toothpaste

Cannabis experts believe in the effectiveness of CBD in oral health. The non-psychoactive cannabinoid has shown some promise as an antiseptic, analgesic, anti-inflammatory, and antibacterial agent, four factors that are essential to mouth health.

CBD, as an antiseptic and antibacterial, may help prevent bacterial growth and even destroy them. These properties may be useful in keeping the teeth and mouth free from any harmful bacteria.

A study showed the antibacterial characteristics of delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD) (2).

Another study, conducted in 2019 by researchers from the University of Queensland, showed CBD might be a capable fighter against bacterial infections (3). 

CBD, as an analgesic, relieves pain. A study published in Therapeutics and Clinical Risk Management showed how employing cannabinoids, such as THC and CBD, helped in the management of difficult-to-treat pain (4).

Another research, published in the Journal of Opioid Management in 2013, highlighted the analgesic potential of cannabinoids (5).

CBD’s potent anti-inflammatory properties, meanwhile, were demonstrated in a 2018 study published in the Journal of Pharmacology and Experimental Therapeutics (6)

 By interacting with CB2 cannabinoid receptors, CBD has the potential to help with swollen and bleeding gums, which are common symptoms of oral diseases.

Why It Is Important to Have Healthy Teeth and Gums

Poor hygiene and weak dental health lead to bad teeth and gum diseases.

With gum disease, bacteria often enters the bloodstream. If the body’s immune system is weak, it becomes susceptible to cardiovascular disease and other medical conditions.

In a 2019 research, published in the Journal of the American Heart Association, bacteria commonly found in the mouth was seen in the brains of people who have had a stroke (7). 

The findings suggested that inflammation in the mouth caused by bacteria might contribute to the progression of cerebrovascular diseases that could lead to a stroke or heart attack.

In a study published in Stroke, a significant association was observed between tooth loss levels and carotid artery plaque prevalence (8). Among those with at least ten missing teeth, carotid artery plaque prevalence was about 60%. 

Carotid artery disease is caused by an accumulation of plaques in arteries that deliver blood to the brain (9).


Inflamed gums that bleed easily during brushing or flossing, bad breath, and receding gums are some indications of gingivitis.

Gingivitis can lead to periodontitis, which causes the gums to break down and teeth to become loose.

All these can be prevented by practicing good dental hygiene and careful oral care management. 

Utilizing the potential benefits of CBD in CBD toothpaste may also help maintain gum and teeth health daily. 

However, before using CBD toothpaste as a supplement to existing therapy for a particular symptom or disease, consult with a doctor experienced in cannabis use for advice. For personal dental advice and care, consult a qualified dental health provider.

  1. Mayo Clinic. (2017, Aug 4). Gingivitis. Retrieved from
  2. Van Klingeren B, Ten Ham M. Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol. Antonie Van Leeuwenhoek. 1976;42(1-2):9–12. DOI:10.1007/bf00399444.
  3. The University of Queensland. (2019, June 24). Cannabis compound could be powerful new antibiotic. Retrieved from
  4. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245–259. DOI:10.2147/tcrm.s1928.
  5. Elikkottil J, Gupta P, Gupta K. The analgesic potential of cannabinoids [published correction appears in J Opioid Manag. 2010 Jan-Feb;6(1):14. Elikottil, Jaseena [corrected to Elikkottil, Jaseena]]. J Opioid Manag. 2009;5(6):341–357.
  6. Petrosino S et al. Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis. Journal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI:
  7. Patrakka O et al. Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy. Originally published 23 May 2019. Journal of the American Heart Association.
  8. Desvarieux M, Demmer RT, Rundek T, et al. Relationship between periodontal disease, tooth loss, and carotid artery plaque: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke. 2003;34(9):2120–2125. DOI:10.1161/01.STR.0000085086.50957.22.
  9. Mayo Clinic. (2018, Oct. 4). Carotid artery disease. Received from
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