Are you looking for an alternative oral care product to help keep your teeth clean and improve dental health? This article discusses how CBD toothpaste may help promote and maintain dental wellness.


  1. How can CBD toothpaste help?

Toothpaste containing CBD as an active ingredient may help with dental problems.

CBD as an antibacterial product may help prevent or destroy bacteria(1). Results of studies suggest CBD may be used to reduce bacteria for oral care(2).

CBD is also purported to have analgesic properties that may be helpful for toothaches(3).

Cannabinoids such as CBD and tetrahydrocannabinol (THC) may help manage periodontal disease or gum infection(4).

These cannabinoids may provide anti-inflammatory and analgesic benefits that may help alleviate chronic pain caused by periodontal disease(5).

  1. What evidence or research exists to say that CBD toothpaste helps?

A 2020 study was conducted to examine the efficacy of cannabinoids, such as CBD (cannabidiol), CBGA (cannabigerolic acid), CBN (cannabinol), CBC (cannabichromene), and CBG (cannabigerol), in reducing bacteria from dental plaque(6).

The study compared commercial oral care products. The researchers noted that cannabinoids like CBD may effectively reduce the bacteria count in dental plaques.

In 2019, researchers from the University of Queensland conducted a study that showed CBD may help fight bacterial infections(7).

Results from these studies suggest that toothpaste with CBD may help with dental problems.

  1. Is there any evidence that CBD toothpaste is not good?

To date, there is no scientific evidence indicating that CBD toothpaste has adverse effects on dental health specifically.

However, CBD may cause side effects like fatigue, dry mouth, drowsiness, appetite loss, and diarrhea(8).

Additional research is required to determine the safety and efficacy of CBD toothpaste on oral wellness conclusively.

  1. Will CBD toothpaste interact with any current medication I may be taking?

Some CBD products come with a grapefruit warning, meaning CBD may prevent or reduce the effectiveness of other medicines.

Grapefruit can prevent the normal breakdown of medications by interfering with proteins in the small intestine and liver.

If you are currently taking medications for toothache, consult a dentist or pharmacist to determine whether your prescription has ingredients that may interact with CBD toothpaste.

  1. Are there other treatments or products that should be considered alongside CBD toothpaste?

Some natural remedies, like clove oil and vanilla extract, may provide pain relief(9). Baking soda is another common ingredient in toothpaste due to its characteristic that may help with dentinal sensitivity(10).

The purported benefits of vanilla extract, clove oil, and baking soda may be why some CBD toothpaste and CBD mouthwash manufacturers include these ingredients in their products.

  1. Can I fail a drug test if I use CBD toothpaste?

CBD products with zero or less than 0.3% THC usually do not cause you to fail a drug test.

However, regularly using CBD products containing THC may increase THC levels(11). Full-spectrum and broad-spectrum CBD products contain little to no THC.

CBD products are currently legal on a federal level. However, the restrictions may vary among states.

Check your state’s laws and review the THC level in the CBD products you are using to know whether using CBD toothpaste is legal in your area.

  1. How much CBD toothpaste should I use?

To date, there are no FDA-approved guidelines that determine the standard amount of CBD in toothpaste. Neither is there any recommended amount of CBD in CBD toothpaste.

However, a 2021 study mentioned that a 15-30mg sublingual dose of CBD oil may help address dental anxiety and dental pain(12).

  1. What is inside the CBD toothpaste?

Ingredients inside a CBD toothpaste may vary. Some products contain similar ingredients as regular toothpaste, such as sorbitol, xylitol, and activated charcoal.

Sorbitol is a carbohydrate known as a sugar alcohol that helps protect teeth against decay. Xylitol is a sugar substitute also used for tooth decay prevention. Activated charcoal is used to whiten teeth.

CBD toothpaste may also include natural ingredients like peppermint oil or tea tree oil.

  1. How should I use CBD toothpaste?

CBD toothpaste is considered a topical product applied on the surface of a body part, such as the teeth and gums.

To use the product, apply a pea-sized amount of CBD toothpaste on the head of a toothbrush. Brushing your teeth for around two minutes at least twice a day helps keep your teeth, gums, and mouth healthy(13).

  1. Is CBD toothpaste psychoactive? Will it get me high?

CBD does not produce psychoactive effects like tetrahydrocannabinol or THC does(14). CBD by itself does not give a feeling of high.

However, some CBD products contain THC. Frequent use of these products may get you high.

  1. What are the benefits of CBD toothpaste?

CBD toothpaste may be used as an antibacterial product to prevent or reduce bacteria(15).

Aside from these properties, CBD may also have analgesic properties that may help relieve tooth pain. This benefit may help manage pain due to tooth extractions and postoperative pain(16).

  1. Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol
  2. Comparison of Efficacy of Cannabinoids versus Commercial Oral Care Products in Reducing Bacterial Content from Dental Plaque: A Preliminary Observation
  3. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
  4. Ibid.
  5. Ibid.
  6. Comparison of Efficacy of Cannabinoids versus Commercial Oral Care Products in Reducing Bacterial Content from Dental Plaque: A Preliminary Observation
  7. Cannabis compound could be powerful new antibiotic
  8. What are the benefits of CBD — and is it safe to use?
  9. Toothache: Causes, symptoms, treatment, and prevention
  10. Effectiveness of a baking soda toothpaste delivering calcium and phosphate in reducing dentinal hypersensitivity
  11. Can You Take CBD and Pass a Drug Test?
  12. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
  13. How to keep your teeth clean
  14. CBD & THC: Myths and misconceptions
  15. Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol
  16. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
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