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Overall CBDC Brand Rating: 9.9/10

Spruce is committed to getting the most effective results from a maximum potency CBD product, using a moonshine extraction method to get the best combination of CBD, low-level THC, and terpenes.

  • Spruce sources its hemp from Colorado and Kentucky, which are known for their sustainable and safe farming practices and highest potency hemp strains.
  • Spruce’s lab-grade CBD oil is 100% organic, vegan, and gluten-free with no artificial flavors, preservatives, or sweeteners. While Spruce’s maximum potency CBD oil is a bit bitter, users agree that “the bitter stuff is the effective stuff.”
  • Spruce CBD oils are full-spectrum oils containing all the cannabinoids, including cannabichromene (CBC), cannabigerol (CBG), cannabinol (CBN), and tetrahydrocannabinol (THC), as well as essential oils, terpenes, and flavonoids. The full spectrum of components works in synergy to produce the “entourage effect,” making them more potent as a combined unit than each is on its own. 
  • Studies have shown the antifungal and antimicrobial effects of CBC (cannabichromene) and CBG (cannabigerol)(1). Meanwhile, research has demonstrated that CBN (cannabinol) possesses anticonvulsant and anti-inflammatory properties(2).
  • Lab results show that Spruce CBD products are free of pesticides, heavy metals, and biotoxins, and the CBD content is at or above the amount reported on the label. All tests are performed by independent, third-party, ISO-certified labs before any Spruce product is allowed in its warehouse.

Best Products from Spruce

Spruce CBD products are made with lab-grade full-spectrum CBD for maximum therapeutic benefits and optimal strength relief. 

Editor's Pick

Spruce 2400mg Lab Grade CBD Oil

Spruce 2400mg Lab Grade CBD Oil Bottle
— Our rating —

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

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Users' Top Choice

Spruce 750mg Lab Grade CBD Oil

Spruce 750mg Lab Grade CBD Oil Bottle

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

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Fur favorite

Spruce Dog CBD Oil 750mg

Spruce Dog CBD Oil 750mg Bottle

Spruce’s dog-friendly CBD has been specially formulated for dogs. Instead of hemp seed oil for the carrier oil, the product contains coconut oil, which is generally easier on the digestion for dogs. The taste is also milder with no flavorings, making it more likely that dogs will eat it with their food.

Using Spruce CBD for dogs is simple. All owners have to do is sprinkle the desired dose on the dog’s food at mealtime once or twice a day. Each dose should consist of about two to three drops per 20 pounds of dog weight.

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Most Popular

Spruce Topical CBD Cream

Spruce Topical CBD Cream Jar
— Our rating —

Each of Spruce’s two-ounce containers of cream contains a total of 300mg of CBD. Users can apply this cream to painful areas as many times as needed. The cream is completely plant-based with moisturizing ingredients such as paraffin and mineral oil.

One thing that users may want to watch out for is that this cream does contain some THC. At 0.3 percent THC, it is a very small amount and unlikely to be absorbed in the body for long. However, users who must go through routine drug tests may want to avoid this product.

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Spruce CBD: Company Analysis

Spruce is a family-owned business based out of Raleigh, North Carolina. The company was founded in 2018 in the belief that modern medicine is broken and that there is a need for alternatives to dangerous pharmaceuticals. 

Spruce’s lab-grade CBD oil is 100% natural and tested by a third-party lab in the United States. Their relationship with U.S. farmers gives them access to the best quality hemp plants and hemp extracts to use in their products. 

Full-spectrum oils, like Spruce CBD oil, contain other cannabinoids in addition to the CBD, including CBN, CBC, and small amounts of THC. 

Thus, Spruce does not recommend that individuals subjected to drug testing take Spruce products. Even though Spruce CBD oil only contains 0.3% THC, there is a chance that the user may test positive for marijuana.

Still, many users prefer Spruce full-spectrum CBD oil since the other cannabinoids present within help the CBD provide fast relief.

Recommended forOptimizing Wellness
Source of HempColorado and Kentucky
Types SoldFull-spectrum 750mg CBD oil and 2,400mg CBD oil, 300mg CBD cream, 750mg CBD oil for pets
Range of Products/FormsFull-spectrum CBD tinctures, CBD cream, CBD for pets
PricesFrom $39 for the 300mg CBD cream to $269 for the 2,400mg Full-spectrum CBD tincture
Extraction MethodMoonshine extraction 
Lab Testing TransparencyThird-party lab results are available online
CBD Concentration per servingSpruce 2,400mg CBD Oil contains 80mg of full-spectrum CBD per ml
PotencyFor Spruce 2,400mg CBD Oil, the CBD concentration (potency) is 81.87 mg/ml
THC Range of Products %For Spruce 2,400mg Lab-Grade CBD Oil, Max THC is 0.26% or 2.39 mg/ml
FlavorsNo added flavors for 2,400mg and 750mg for pets. Peppermint flavor for 750mg.
Lab Testing AvailabilityAvailable on the website and accessible with a QR code
Tincture Carrier OilHemp seed oil or Coconut MCT oil for 2,400mg CBD Oil; Hemp seed oil for 750mg; Coconut MCT oil for 750mg CBD for pets
Price RangeFrom $39 for the 300mg CBD cream to $269 for the 2,400mg CBD tincture
ShippingSpruce ships first class USPS every weekday morning at 9 AM EST
DeliveryShipments usually arrive in 2 to 4 business days
GuaranteeResults of third-party lab tests show that Spruce products contain exactly the amount of CBD stated in their labels, if not slightly more
ContaminantsZero contaminants
Vegan and Gluten-freeVegan and gluten-free
Refund PolicyTo receive a refund, returns must be made within 30 days of purchase
Customer ServiceCall Spruce at 866-964-7508
Countries ServedCurrently, Spruce is only shipping within the U.S.

Spruce’s Max Potency CBD Oil products are recommended for those who want to experience the full therapeutic benefits that come only when the full spectrum of cannabinoids and terpenes work in synergy.

However, their extracts contain no additives, and pure hemp oil has a naturally grassy or earthy taste, which first-time users may not find very inviting or tasty. 

Thus, to camouflage the slightly bitter taste, some users opt to include a few drops of the pure CBD oil tincture in their food and drinks.

Meanwhile, Spruce’s lower-strength tincture, with 750 milligrams of CBD, comes in a natural peppermint flavor, allowing new users to get all the benefits of a full-spectrum CBD oil in a refreshing minty taste.

Source of Hemp: 

Spruce’s two primary farms, one in Colorado and another one in Kentucky, are known for their safe and sustainable farming practices and are producing some of the highest quality and highest potency hemp strains available for use for CBD.

Spruce 750mg CBD Oil and 2,400mg CBD Oil – Lab-grade full-spectrum CBD Oil in the most potent formulation for maximum strength relief.

Spruce 300mg CBD Cream – Lab-grade full-spectrum CBD, in a silky-smooth, fast-absorbing cream for targeted relief applied directly to the skin. This max strength formula may be applied as often as needed.

Spruce Dog-Friendly 750mg CBD Oil – Spruce’s best lab-grade full-spectrum CBD Oil specially formulated for furry friends. To use, just drop on their food.

Editor's Pick

Spruce 2400mg Lab Grade CBD Oil

Spruce 2400mg Lab Grade CBD Oil Bottle
— Our rating —

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

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Users' Top Choice

Spruce 750mg Lab Grade CBD Oil

Spruce 750mg Lab Grade CBD Oil Bottle

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

Check Latest Price
Fur favorite

Spruce Dog CBD Oil 750mg

Spruce Dog CBD Oil 750mg Bottle

Spruce’s dog-friendly CBD has been specially formulated for dogs. Instead of hemp seed oil for the carrier oil, the product contains coconut oil, which is generally easier on the digestion for dogs. The taste is also milder with no flavorings, making it more likely that dogs will eat it with their food.

Using Spruce CBD for dogs is simple. All owners have to do is sprinkle the desired dose on the dog’s food at mealtime once or twice a day. Each dose should consist of about two to three drops per 20 pounds of dog weight.

Check Latest Price
Most Popular

Spruce Topical CBD Cream

Spruce Topical CBD Cream Jar
— Our rating —

Each of Spruce’s two-ounce containers of cream contains a total of 300mg of CBD. Users can apply this cream to painful areas as many times as needed. The cream is completely plant-based with moisturizing ingredients such as paraffin and mineral oil.

One thing that users may want to watch out for is that this cream does contain some THC. At 0.3 percent THC, it is a very small amount and unlikely to be absorbed in the body for long. However, users who must go through routine drug tests may want to avoid this product.

Check Latest Price

 

Types Sold: 

Spruce products use CBD oils that are full-spectrum oils consisting of multiple cannabinoids and other healthy substances, such as essential oils and terpenes collected during the whole-plant extraction process. All these constituents work together in synergy to magnify the therapeutic benefits of each cannabinoid in a phenomenon called the “entourage effect.”

Some of the cannabinoids found in full-spectrum CBD tinctures are cannabichromene (CBC), cannabigerol (CBG), cannabinol (CBN), and tetrahydrocannabinol (THC).

Range of Products/Forms: 

Spruce’s product line-up is currently limited to CBD tinctures (750mg CBD Oil and 2,400mg CBD Oil) and 300mg Topical CBD Cream. They also have a Dog-Friendly 750mg CBD Oil.

Prices: 

Prices of Spruce products range from $39 for the 300mg CBD cream to $269 for the 2,400mg CBD tincture.

Extraction Method:  

Spruce uses the moonshine extraction method, which provides for a higher-quality of CBD than CO2 extraction, to guarantee the best combination of CBD, low-level THC, and terpenes.

The term “moonshine” used to refer to any high proof distilled alcohol that was illicitly produced or procured. Nowadays, moonshine is a type of alcohol that CBD manufacturers use in the extraction of CBD. 

The moonshine extraction technique not only preserves more than 80 beneficial phytocannabinoids but also filters out residual plant materials. 

After the extraction process and before the CBD oil is bottled, all of the moonshines are completely filtered out of their product, ensuring that what is left behind is nothing but pure, full-spectrum CBD oil that is clear in color.

Raw, unprocessed oils are very dark in color and sometimes even have a greenish tone, which is indicative of residual plant material and chlorophyll.

Lab Testing Transparency:

Spruce practices complete transparency and pay for third party, U.S. labs to test every batch of its products. 

Spruce’s lab results show that their products are free of pesticides, heavy metals, and biotoxins, and the CBD content is at or above the amount reported on the label. 

All tests are performed by independent, ISO-certified labs before any Spruce product is allowed in its warehouse.

 Every batch of Spruce products is post-formulation lab-tested, and results are available on its website.

CBD Concentration per serving range:

Spruce 2,400mg Lab-Grade CBD Oil contains 80mg of full-spectrum CBD per dropperful (1ml), which is a maximum level of potency in a 30ml bottle.

Potency:

The concentration of a cannabinoid is reported in milligrams per gram of the product. The ‘Conc.’ or ‘Concentration’ column in the certificate of analysis is the potency of the tested CBD oil, which should be compared to the CBD concentrations advertised on the label of the product.

For Spruce 2,400mg Lab-Grade CBD Oil, the CBD concentration (potency) is 81.87 mg/ml.

One can determine potency by evaluating the concentrations of each cannabinoid present in the sample. The potency is determined by measuring the concentration of cannabinoids present in terms of total percentage by weight (mass).

On the first page of the certificate of analysis (COA), the weight indicates the percentage of cannabinoid present in the overall product. Concentration is the amount of cannabinoid broken down into milligrams per gram for reference.

THC Range of Products (less than 0.03% – non-psychoactive): 

For Spruce 2,400mg Lab-Grade CBD Oil, Max THC is 0.26% or 2.39 mg/ml. Max CBD is 9.18% or 83.35 mg/ml.

The ratio of total CBD to THC is 34.9:1 for the 2400mg CBD oil. Max THC and max CBD are the calculated values for overall cannabinoids after heating, considering complete decarboxylation of the acid to the neutral form.

Decarboxylation is a chemical reaction that results from heating a cannabinoid to enhance its ability to interact with the body’s receptors. 

Decarboxylation converts the primary phytocannabinoids in cannabis, such as CBD and THC, into active molecular forms, increasing the cannabinoids’ bioavailability, and making more of it available to the body’s cells.

Flavors: 

The 750mg CBD oil from Spruce has a refreshing and appealing peppermint taste that masks the natural grassy flavor of hemp well.

Meanwhile, Spruce’s 2,400mg maximum potency CBD oil has a much more earthy and a little bit bitter taste, as no flavoring is added to this variety to allow for the maximum CBD potency in a 30mL bottle.

Lab Testing Availability: 

Lab results for testing of Spruce products are available on the website and accessible with a QR code.

Tincture Carrier Oil: 

Customers are given an option between organic hemp seed oil and organic coconut MCT oil as carrier oil when they purchase Spruce products online.

Lab Results:

Lab results for testing of Spruce products are available on the website and accessible with a QR code.

Price Range: 

Prices of Spruce products range from $39 for the 300mg CBD cream to $269 for the 2,400mg CBD tincture.

Shipping or Delivery: 

Spruce ships every weekday morning at 9 AM EST, and shipments usually arrive in 2 to 4 business days. Spruce ships first class USPS and cannot currently offer any expedited services such as FedEx or UPS. 

All orders placed before 9:30 AM Eastern Time on a business day ships out the same day. Orders placed after 9:30 AM ships out the following business day. 

Standard shipping is provided by USPS First Class Mail and has an estimated delivery time of 2-4 business days after they ship it. Tracking is included, but the delivery date is not guaranteed.

However, in the event an item ordered is out of stock, Spruce ships the items available and ships the out of stock item(s) as soon as they become available via an expedited method at no cost to the customer.

Spruce’s free shipping offer applies to any orders on products labeled “free shipping”  to a shipping address within the United States. 

Guarantee: 

Spruce CBD oils are full-spectrum CBD oils that contain all the cannabinoids, terpenes, and flavonoids found in the hemp plant. To ensure the best high CBD, low THC combination, Spruce uses the moonshine extraction method, which provides for a higher-quality of CBD than CO2 extraction.

Spruce 2,400mg extra strength CBD oil tastes a little bitter, as it has no added flavoring. However, the bitter stuff is the effective stuff. With nothing else but pure, full-spectrum CBD oil, the maximum therapeutic benefits of CBD are guaranteed.

Results of third-party lab tests showed that Spruce products contain exactly the amount of CBD stated in their labels, if not slightly more.

Contaminants: 

Spruce products are safe, consistent, effective, and free from all contaminants. Independent third-party lab tests show that Spruce has never had a failure on screenings for any pesticides, bacteria, or other harmful contaminants. 

Vegan and Gluten-free: 

  Spruce products are vegan and gluten-free.

Refund Policy:

Customers may return products for any reason and receive a full refund. However, to be considered for reimbursement, products purchased through standard delivery must be unopened and in the original packaging. 

The first purchase only requires the empty or partially empty container to be returned. To return a product, call Spruce at 866-964-7508 within 30 days of purchase. Product issues not declared within 30 days of purchase are not entitled to a refund. 

Customers are then given a Return Merchandise Authorization (RMA) number. To receive the refund, they must postmark their return within 30 days of purchase. 

Customers must clearly write the RMA number on the outside of the box. Spruce’s shipping department does NOT accept any packages without an RMA number. 

Address the return package to Spruce Natural Labs LLC,1053 E. Whitaker Mill Rd., Suite 115-H, Raleigh, NC 27604. Customers pay for return shipping, and they must get proof of shipment. 

Upon receipt of the returned product with a valid RMA number, a refund is issued to the customer’s credit card for a full refund of the purchase price, including shipping and handling. 

After the shipping department receives the return, it takes 3 to 5 business days to process the refund. Once processed, it can take up to one billing cycle for the return to be posted to the customer’s account, depending on his or her financial institution.

Customer Service: 

Once an order has shipped and the carrier has generated a tracking number, the customer is emailed the tracking information. For further assistance, customers may call 866-964-7508.

Spruce also has a subscription plan that ships every month automatically, provides 15% off, free shipping, priority when inventory is low and can be canceled or changed at any time.

If a customer needs to change the speed of the shipment or cancel, he or she can let Spruce know via the web chat or by email for the changes to be applied immediately.

Countries served: 

Currently, Spruce is only shipping within the US, although they hope to expand soon. On their website, they say that they have just had too many losses when packages have been seized by border control.

Summary: 

Pros

Cons

Full-spectrum CBD extracts from 100% organic, pesticide-free hemp plants2,400mg CBD tinctures have a slightly bitter taste
All-natural, vegan, and gluten-freeLimited product selection
Third-party lab tested for safety and purityCurrently ships only within the U.S.
Simplified product line 
Practices complete transparency
Offers free shipping on orders within the U.S.

Pros of the company

  • Spruce products are made with full-spectrum CBD extracts from 100% organic, pesticide-free hemp plants.
  • Spruce products are all-natural, vegan, and gluten-free, and they are third-party lab tested for safety and purity.
  • The simplified product line is easy to understand, making purchase decisions uncomplicated.
  • Spruce practices complete transparency, as every batch of products is post-formulation lab-tested, and test results are available on its website.
  • Spruce offers free shipping on all orders within the USA.

Cons of the company

  • Spruce 2,400mg CBD tinctures have a slightly bitter taste
  • The limited product selection does not have THC-free options or products such as gummies, capsules, and vape juice.
  • Currently, Spruce only ships within the USA.

Review of Spruce 2400mg Max Potency CBD Oil CBD Oil

Spruce 2,400mg “Extra Strength” CBD Oil Tincture is a lab-grade, full-spectrum CBD oil, formulated to high potency for maximum therapeutic benefits.

One dropper full, equivalent to 1ml, contains 80mg of CBD that is vegan, gluten-free and contains no artificial preservatives or sweeteners. 

When customers purchase the oil online, they can choose between hemp seed oil and coconut MCT oil as the carrier oil for their CBD tincture.

However, there is no flavor to choose from, as this high-potency variety comes unflavored. Its taste may even be a bit bitter, owing to the naturally grassy, earthy taste of pure hemp extract.

Still, Spruce believes that “The bitter stuff is the effective stuff,” and most customers agree. With nothing else but pure, full-spectrum CBD oil, the maximum therapeutic benefits of CBD are guaranteed.

Review of Spruce 750mg CBD Oil 

For a slightly less potent tincture that still offers maximum benefits, customers may choose Spruce’s 750mg CBD blend. 

Its only ingredients are organic hemp seed oil, full-spectrum CBD oil, and natural flavors. One dropper full, equivalent to 1ml, contains 25mg of CBD that is vegan, gluten-free and contains no artificial preservatives or sweeteners. 

Spruce’s 750mg CBD is also recommended for new CBD users or those who want to test out the effects before committing to a higher potency product. Then, as users become accustomed to the effects of CBD oil, dosing may be adjusted gradually to achieve the desired results. 

Unlike the Max Potency variety, this 750mg CBD blend is formulated with natural peppermint, adding a refreshing and minty flavor to the oil.

As with all Spruce CBD tinctures, customers are advised not to take this product if they undergo drug testing. Even though Spruce CBD oils only contain 0.3% THC, there is a chance that users may test positive for marijuana.

Review of Spruce 300mg Topical CBD Cream

This CBD topical is made from lab-grade full-spectrum CBD that can be applied to specific areas of the body for targeted relief. 

Each 2-ounce jar contains 300 milligrams of CBD with a pleasant scent, derived from all-natural plant-derived ingredients. 

The list of other ingredients includes water, mineral oil, petrolatum, glycerin, microcrystalline wax, lanolin alcohol, paraffin, panthenol, magnesium sulfate, decyl oleate, octyldodecanol, aluminum stearates, fragrance, citric acid, magnesium stearate, methylchloroisothiazolinone, and methylisothiazolinone.

Spruce CBD cream provides intense moisture when applied directly to the skin. The silky-smooth, fast-absorbing blend is effective for targeted relief and may be applied as often as needed.

Research published in the European Journal of Pain studied the effectiveness of taking CBD oil topically, either alone or as part of a lotion or cream. The authors found that “topical CBD application had the therapeutic potential for relief of arthritis pain-related behaviors and inflammation without evident side-effects.”(3) 

Meanwhile, the Rheumatoid Arthritis Support Network (RASN) tested dozens of products amongst its staff and through its network of RA readers and found Spruce CBD to be the most effective among other CBD brands(4).

Review of Spruce 750mg CBD Oil for Dogs

Spruce’s CBD oil for dogs is made from the same high quality, full-spectrum lab-grade CBD tincture for humans, but explicitly packaged for dogs. It contains <0.3% THC.

This unflavored blend is made with coconut MCT carrier oil, as it is easier on a dog’s digestive system. 

The MCT oil also masks some of the bitter taste of the natural CBD oil, making the taste a bit milder, which reduces the chance of the dogs being unhappy with it placed on their food. No other flavoring is added to this CBD oil. 

To use, simply drop the appropriate amount on the dog’s food once or twice daily. Picky eaters may need it stirred in, or covered with some food.

Dosing Guidelines

Pet Weight

Usage

Up to 25lbs/11kg 2 drops – 1-2 times daily on the dog food
25 – 50lb/11 – 23kg4 drops – 1-2 times daily on the dog food
50 – 75lb/23 – 34kg6 drops – 1-2 times daily on the dog food
Over 75lb/34kg 8+ drops – 1-2 times daily on the dog food

Spruce CBD oil for dogs contains less than 0.3% THC. Pet owners are also forewarned that this CBD oil contains tree nuts (coconut), which may cause allergic reactions to some pets. 

A Close Look at CBD 

Why Choose Full-Spectrum CBD Oil?

The two primary types of CBD are CBD isolate and full-spectrum CBD oil, and consumers must understand the differences. 

Full-spectrum CBD oil has all of the cannabinoids that can be extracted from the cannabis plant, and it offers a more excellent range of benefits than pure CBD isolate. 

Isolate CBD is pure CBD only and does not contain other types of cannabinoids that are naturally found in cannabis plants.

While CBD isolate is considered to be more potent or concentrated than other CBD products, this does not make it superior. The high potency of the isolate cannot rival the combined effects of the various cannabinoids contained in full-spectrum CBD oil products.

In choosing the best CBD oil, opt for the one that contains full-spectrum CBD oil.

How does CBD work?

Cannabinoids are complex chemical compounds found within the Cannabis sativa plant. Similar to the hemp plant, which produces more than 100 different cannabinoids (phytocannabinoids), the human body also naturally produces cannabinoids (endocannabinoids).

The endocannabinoid system (ECS) helps to manage functions such as immune-system responses, sleep, and pain, influencing a person’s physiology, mood, and everyday experience. 

A study published in the Pharmacological Reviews Journal explored the endocannabinoid system and its regulatory functions in health and disease(5). 

The neurotransmitters in the brain provide instructions for the body’s immune system and signal it when to activate its line of defense, where to engage it, and how strongly to involve it. 

What are the benefits of CBD?

CBD has been shown to possess numerous potential health benefits that may help with many ailments and medical conditions, including chronic pain, anxiety, sleeping problems, and arthritis(6). 

Other users find that the cannabinoids within CBD products not only provide general pain relief but also help with mental health conditions. 

For instance, a case series in the Journal of Alternative and Complementary Medicine shares that CBD has been found helpful in reducing the severity of symptoms commonly associated with post-traumatic stress disorder (PTSD), one of which is frequent nightmares(7). 

However, more longitudinal and comprehensive studies are needed to obtain high-quality evidence of CBD’s efficacy against specific medical conditions.

Also, CBD products might not always be the best option for those currently taking prescription medications, as CBD could interact with specific drugs and cause adverse side effects.

Thus, before using CBD for the first time or including CBD in a regimen, consult with a doctor experienced in cannabis use.

CBD is readily obtainable in many parts of the United States, although its exact legal status continually changes. 

In December 2015, the U. S. Food and Drug Administration (FDA) eased the regulatory stipulations to allow researchers to conduct CBD investigations and trials. Currently, many people can get CBD online without a medical cannabis license(8). 

For a complete list of legal medical marijuana states and D.C., including the corresponding laws, fees, and possession limits, click here(9).

Conclusion

While the Spruce brand is new, it is already making its name known in the highly-competitive CBD industry. Spruce is often listed as one of the best CBD oils on the market, together with old-time players like NuLeaf Naturals.

Spruce is a family business founded in the belief that modern medicine is broken and in need of alternatives to dangerous pharmaceuticals. Their mission to use only high-quality ingredients is commendable. 

Spruce’s decision to focus on a few products and make them as potent as possible is an indication that they put the integrity and quality of their products above everything else.

Spruce’s priorities rely more on quality and less on competing with other CBD brands with a wide range of products. Thus, making purchase decisions with Spruce is never a complicated matter.

Spruce’s transparency shows its commitment to its customers, wanting to make sure that users know what goes into each of its products. Spruce wants its customers to make a safe, confident, and informed decision about their CBD purchase. 


  1.  Eisohly HN, Turner CE, Clark AM, Eisohly MA. Synthesis and antimicrobial activities of certain cannabichromene and cannabigerol related compounds. J Pharm Sci. 1982 Dec; 71(12):1319-23. DOI: https://doi.org/10.1002/jps.2600711204.
  2. Turner CE, Elsohly MA, Boeren EG. Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod. 1980 Mar-Apr; 43(2):169-234; Evans FJ. Cannabinoids: the separation of central from peripheral effects on a structural basis. Planta Med. 1991 Oct; 57(7):S60-7.
  3. Hammell DC, Zhang LP, Ma F, et al. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur J Pain. 2016;20(6):936–948. doi:10.1002/ejp.818
  4. Freeman, J. (2020, Mar 1). RheumatoidArthritis.org. Retrieved from https://www.rheumatoidarthritis.org/cbd-oil/.
  5. Pacher P, Bátkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev. 2006;58(3):389–462. doi:10.1124/pr.58.3.2.
  6. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245–259. doi:10.2147/tcrm.s1928; Crippa JA et al.Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.J Psychopharmacol. 2011 Jan;25(1):121-30. doi: 10.1177/0269881110379283. Epub 2010 Sep 9. DOI: 10.1177/0269881110379283; Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18–041. doi:10.7812/TPP/18-041; Booz GW. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med. 2011;51(5):1054–1061. doi:10.1016/j.freeradbiomed.2011.01.007.
  7. Elms, L et al. “Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series.” Journal of Alternative and Complementary Medicine. Apr 01, 2019; 25(4): 392-397. doi: 10.1089/acm.2018.0437. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482919/.
  8. Grinspoon, P. (2019, Aug 27). Cannabidiol (CBD) — what we know and what we don’t. Retrieved from https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476.
  9. ProCon.org. (2019, July 24). Legal Medical Marijuana States and DC Laws, Fees, and Possession Limits. Retrieved from https://medicalmarijuana.procon.org/legal-medical-marijuana-states-and-dc/.

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