How can CBD be beneficial for horses?

  • Horses experience chronic pain and medical conditions such as arthritis, gastric ulcers, laminitis, anxiety, obesity, and more.
  • Research has shown that CBD Oil possesses beneficial health properties such as anti-inflammation, pain relief, anxiety inhibition, and more(1).
  • The Endocannabinoid system (ECS), which interacts with cannabinoids like CBD, is present in all mammalian life(2).
  • Only a few CBD studies were conducted on horses as subjects.
  • However, most human and animal studies conclude that CBD is effective in lessening inflammation and pain experienced by those with arthritis(3).

Best CBD Oil for Horses

Best Equine CBD Oil

cbdMD Pet CBD Oil Tincture for Horses

Premium CBD for your trusty steed
cbdMD Pet CBD Oil Tincture for Horses
  • Overall Clinical Score
    99%
    Best Equine CBD Oil
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    If an apple a day keeps the doctor away, then this apple-flavored CBD can help keep your favorite equine happy between veterinary visits.

    Pro's
    Cons's
     One of the few companies that offer CBD Oil for horses  Low terpene and cannabinoid profile
     Same CBD Oil benefits as for humans  Available in single flavor only
     No THC Animal-specific products (dogs, cats, horses)
     Made from premium CBD from non-GMO USA hemp
  • Features
    Discount pricing available?15% Off Coupon Code: cbdMD15
    Source
    Source of Hemp
    Kentucky, USA
    FormOil Tincture
    IngredientsCannabidiol (CBD), MCT Oil, and Apple Flavoring
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2 extraction method
    How to take itDifferent types of horses have different physiques, so there’s no one-size-fits-all application. Usually, the best approach is to start with a lower intake every day and seeing how your horse responds, adjusting measurements as needed
    Potency
    Potency - CBD Per Bottle
    5000 mg / bottle
    Carrier OilMCT Oil
    Concentration
    CBD Concentration Per Serving
    166.67 mg per dropper (1ml)
    Drug TestNot applicable
    FlavoursApple
    Price Range$239.99
    $/mg CBD
    Price ($/mg)
    $0.05
    Shipping
    Shipping/Time to delivery
    2-5 Business days (via Fedex)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants100% organic, non-GMO, and vegan-certified
    AllergensVegan, Gluten free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedUSA only (all 50 states)
Check Latest Prices

Holista Pet CBD Oil for Horses

Fast-acting and can be given to other livestock animals
Holista Pet CBD Oil for Horses
  • Overall Clinical Score
    99%
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    HolistaPet CBD Oil for Horses is formulated with pure CO2 extracted Full Spectrum CBD Oil and Hemp Seed Oil. This creates a powerful concentration of CBD that you can easily give to your horse.

    Pro's
    Cons's
     High potency  No other flavor
     100% natural
     More affordable compared to other brands
     Can be given to other Livestock animals
  • Features
    Source
    Source of Hemp
    USA (State not specified on website)
    FormOil Tincture
    IngredientsCBD Oil, Hemp Seed Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    CO2 Extraction
    How to take itApply orally or mix with food or water
    Potency
    Potency - CBD Per Bottle
    7500mg
    Carrier OilHemp Seed Oil
    Concentration
    CBD Concentration Per Serving
    62.5mg per dropper full (1ml)
    Drug TestNot applicable
    FlavoursNone
    Price Range$294.95
    $/mg CBD
    Price ($/mg)
    $0.03
    Shipping
    Shipping/Time to delivery
    Free Economy Shipping - 1 to 5 days, Priority Mail Shipping - 2 to 3 days
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsPesticide-free
    AllergensNon-dairy and gluten-free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedUSA only except California
Check Latest Prices
Best Horse Health Support

Honest Paws CBD Oil for Horses

Helps boost your horse's immune system and cognitive health
Honest Paws CBD Oil for Horses
  • Overall Clinical Score
    99%
    Best Horse Health Support
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    Give your horses the golden years they deserve by boosting their immune system and cognitive health to prevent loose lips, a rougher coat, less mentally alert, droopy fetlocks and allergies with daily dose of Honest Paws CBD Oil.

    Pro's
    Cons's
     100% natural  No other flavor
     Chemical-free  Low potency
     THC-free
  • Features
    Source
    Source of Hemp
    Colorado, USA
    FormOil Tincture
    IngredientsOrganic Full Spectrum Hemp Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    CO2 Extraction
    How to take itApply orally
    Potency
    Potency - CBD Per Bottle
    1500mg
    Carrier OilHemp Oil
    Concentration
    CBD Concentration Per Serving
    25mg per dropper full (1ml)
    Drug TestNot applicable
    FlavoursNone
    Price Range$149.95
    $/mg CBD
    Price ($/mg)
    $0.09
    Shipping
    Shipping/Time to delivery
    Standard Shipping - 2 to 6 business days, 2 Day Express Shipping via DHL or USPS
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsContaminant-free
    AllergensSoy-free and Corn-free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedContinental United States (except California), U.S. Territories and U.S. Military Bases outside USA
Check Latest Prices

Why Horse Owners are Turning to CBD Oil for Horses

CBD research on both animals and humans have revealed its therapeutic properties, providing anti-inflammatory, pain-relieving, anxiety-inhibiting benefits, and more(4).

CBD, a type of cannabinoid found in the Cannabis sativa plant, is also being tapped as an alternative treatment for horses.

Its therapeutic properties can inhibit the chronic pain, arthritis, laminitis (hoof inflammation), ulcers, and anxiety experienced by horses.

Horses and humans as a species are not alike. 

However, a study conducted on horse genomics (domestication) showed that over 130 genetic horse traits were similar to humans.

Similar traits shared included muscle disorders, allergies, and even asthma.

Researchers then concluded the traits ideal as models for studying similar human conditions.

The way orthopedic disease and certain cancers affected the horse’s body was also crucial in understanding how it affected humans as well(5).

On a similar note, researchers commonly used horses as models for studying musculoskeletal diseases and arthritis in humans(6).

Their articular cartilage (the tissue between joints) is the most similar to humans.

However, there exist few cannabinoids (chemicals like CBD found in the Cannabis sativa plant) studies conducted on horses.

Most of the research available instead tested humans and other animals such as mice, rats, and pigs.

The majority of information available to date is anecdotal, from horse owners who personally administered CBD products like pellets and tinctures to their equine (horse) mammals.

Stories of horse owners using CBD Oil as an alternative treatment are prevalent. These pet owners resorted to using CBD Oil when no other treatment or medication was useful for their horses’ ailments.

Veterinarians are also advocating for the use of CBD Oil on pet animals due to its encouraging results.

Despite the positive feedback, individuals must consult veterinarians before administering CBD to their horses.

Pain, Inflammation, and Arthritis in Horses

Horses have large bodies, making them prone to inflammatory diseases like arthritis, which often leads to lameness in horses.

Degenerative Joint Disease or arthritis occurs when there is swelling in the joints. Asides from swelling, its symptoms also include pain, stiffness, and the inability to move for longer distances.

As early as 2000, a study conducted on mice revealed that CBD was able to block the progression of arthritis effectively(7).

They discovered that the mice’s joints were protected against severe damage and that CBD was capable of blocking a rise in tumors.

The researchers concluded that its immunosuppressive and anti-inflammatory properties had a potential anti-arthritic effect in the mice, and possibly other animals as well.

Another study also utilized CBD as an alternative treatment for reducing inflammation and pain-related symptoms experienced by rats.

Researchers noted that existing arthritis treatments often produced side effects because of the active ingredient content and the way these are administered.

According to them, CBD possessed the capacity to reduce inflammation without causing adverse side effects(8).

The results indicated that applying CBD topically (on the skin) had a potential for providing arthritis pain-related behaviors as well as inflammation with no side effects.

However, horses are large animals with long generation intervals (average time from the birth of one generation to the birth of the next).

They are not the ideal species model for studying human physiology and health conditions(9).

One significant study tested horses’ response to cannabinoids as an alternative treatment for long-term osteoarticular disease(10).

CBD or cannabidiol is just one of the hundreds of cannabinoids (chemicals) found in the Cannabis sativa plant.

Osteoarticular or rheumatic diseases are common amongst horses. It is characterized by various medical issues concerning bones, cartilage, muscles, ligaments, tendons as well as joint inflammation.

This disease is commonly treated with steroids and nonsteroidal anti-inflammatory therapy.

Researchers proposed that using cannabinoids could potentially provide equine pain relief for rheumatic diseases, as well as osteoarthritis.

They concluded that cannabinoids were effective in remedying pain experienced by horses with arthritis.

Another cannabinoid study conducted on a 4-year-old horse mare also showed promising results(11).

For 5 weeks, the horse was reported to have a marked sensitivity when touched near the shoulder region. 

It was diagnosed with mechanical allodynia (pain experienced with a light brush stroke).

The mare was first given regular pain treatment, with no signs of improvement.

The horse was eventually administered with cannabidiol orally, with a dosage of 250mg twice daily. After 2 days, the pain was resolved.

Horse Anxiety and Depression

Horses are also known to experience anxiety and depression. Horse owners and trainers are a constant witness to this behavioral issue.

Studies show that horses become depressed in confined domestic settings and harsh conditions(12).

Anxiety is also often experienced by horses in training(13).

CBD is known to have positive effects on lessening psychotic, anxiety, and depressive behaviors in existing animal models(14).

Gastric Ulcers and Digestive Issues

Horses also suffer from digestive issues, especially gastric ulceration (stomach ulcers). 

One research found that even foals (young horses) were prone to developing high stomach acidity levels immediately after birth(15).

Various literature suggests that horses in training were most susceptible to developing ulcers, with a 70%-95% prevalence rate(16).

It could even be as high as 100% when data is filtered only to those actively racing.

Performance horses were also among those evaluated in the study. Active show horses had a 58% prevalence rate, endurance horses (used for long-distance racing) had 93% during competition season.

49% of horses who were known to have colic (abdominal pain) were also diagnosed with gastric ulceration.

Humans and various animals from mice to horses have CB1 receptors.

CB1 are cannabinoid receptors and are part of the endocannabinoid system (ECS).

The ECS is integral in regulating many of the bodily functions, from pain to appetite and even memory.

CB1 can reduce the contractions of muscles found in the gastrointestinal tract(17).

There are no studies on the treatment of gastric ulcers using CBD. However, certain cannabinoids are CB1 receptors.

These receptors activate CB1. When CB1 is activated, it is able to lessen gastric acid secretion.

Obesity and Appetite Control

Horses are also subject to metabolic disorders. A key characteristic in Equine metabolic syndrome (EMS) is insulin resistance resulting in obesity.

Both obese horses and ponies diagnosed with EMS were most susceptible to laminitis, another painful equine medical condition(18).

Research also suggests that cannabinoids play a crucial role in obesity(19).

A study done on mice suggests that administering a CBD2 receptor agonist could reduce body weight gain even though food intake will not be reduced(20).

CBD is a CB2 receptor inverse agonist, which could also explain its anti-inflammatory properties(21).

Similarly, obesity is often underlying for inflammatory and metabolic diseases(22).

How CBD Oil Works to Help Horses

Cannabinoids, including CBD, work in a similar process throughout all mammals and vertebrates, hence the beneficial effects of CBD on horses(23).

When CBD interacts with the body’s ECS, the therapeutic effects are activated through the binding of receptors.

Both are located in the mammalian brains, nervous systems, and tissues connected to the immune system(24).

CB1 receptors modulate motor regulation, memory, appetite, pain, mood, and sleep(25).

On the other hand, CB2 receptors are located in the immune system and its related processes.

When triggered, CB2 receptors trigger responses that lessen inflammation, pain, and damage to tissues. 

The interactions of CBD with CB2 receptors are behind its anti-inflammatory processes(26).

Cannabidiol (CBD) is only one of the hundreds of cannabinoids found in the Cannabis plant.

CBD Oil is extracted from the hemp plant, a variety of Cannabis sativa.

Unlike THC, CBD does not have psychoactive effects and does not give its users a  high(27).

Despite CBD’s similar function in all mammals, its target receptors may differ between humans and animals like horses(28).

Despite CBD’s similar function in all mammals, its target receptors may differ between humans and animals like horses.

Even if the targets are similar, the duration of binding and its affinity to bind may be distinct from one another.

This may affect CBD’s overall effectiveness, and results may vary between humans and animals alike.

The Pros and Cons of CBD Oil for Horses

Pros

  • The ECS, which is responsible for regulating cannabinoids like CBD, functions similarly in all mammalian life(29).
  • Administering controlled CBD may be safe for both humans and animals(30).
  • CBD has an excellent safety and side-effect record for both humans and animals despite their wide variety of dosages(31).
  • Several animal studies show positive effects from CBD treatment for arthritis and inflammation, often common ailments plaguing horses.
  • Many CBD Horse Products exist on the market, from pellets to pastes.

Cons

  • CBD is known to interact with other medications taken alongside it(32).
  • CBD cannot be taken for horses while in competition, as announced by FEI (International Federation for Equestrian Sports) and USEF (United States Equestrian Federation). One of the competition rules include horses having to take drug tests to ensure that they did not previously take cannabinoids(33).
  • CBD Studies done on animals reported side effects like reduced fertility, altered cell function, and inhibition of drug metabolism and transporters(34).
  • Prices for CBD Horse Products can be prohibitive.

How CBD Oil Compares to other Treatment for Horses

Studies have shown that cannabinoids like CBD can be a good anti-inflammatory treatment for osteoarticular diseases found in horses(35).

The current therapy is steroids-based and produces adverse side effects.

Improper use of corticosteroids (class of drugs that reduce inflammation) often results in laminitis, infections, and further injury to horses.

Despite this, CBD Oil is not a miracle cure for horses’ diseases. It can only alleviate some of the symptoms (pain, inflammation).

Consulting with a veterinarian before using CBD products for horses is still a must.

How to Choose the Best CBD Oil for Horses

When choosing CBD products for equine care, horse owners can pick between full-spectrum, broad-spectrum, or isolate CBD.

Full-spectrum contains the most number of cannabinoid strains, from terpenes, flavonoids, to compounds and minerals such as Omega-3 and Omega-6 fatty acids. This provides the “entourage effect.”

Broad-spectrum, on the other hand, is similar but except it being either THC-free or having less than 0.3% THC.

CBD isolates are pure CBD Oil.

Not all CBD products are the same. However, horse owners should only purchase high-quality products to ensure the safety of their horses and for maximum effectiveness.

When choosing the CBD for horses, consider the following:

  1. Before making a purchase, review the legal stipulations applicable to CBD in the state that it will be bought and used.
  2. Look for companies with high ethical standards, good manufacturing practices (cGMP), COA (certificate of analysis), and third party lab certificates of analysis available for every batch of oil.
  3. Look for product reviews and customer testimonials.
  4. Prioritize purchasing GMO-free, organic hemp-derived CBD Oil products from legitimate sellers and brands.
  5. Make sure to check if the CBD products are tested and confirmed to be contaminant-free from pesticides.
  6. Search for CBD Horse Products that use  CO2 extracted technology. This method allows for the safe and clean extraction of all essential cannabinoids, terpene oils.
  7. Make sure the brand has sufficient animal expertise to be manufacturing CBD products for horses.
  8. When buying from a physical store, check if it is officially authorized by the FDA (Food and Drug Administration).
  9. Follow the manufacturer’s instructions on administration and dosing.
  10. Consult with a veterinarian before administering CBD as a treatment for ailments the horse may experience. These may be clinical signs of a severe disease.

Best CBD Oil for Horses

Best Equine CBD Oil

cbdMD Pet CBD Oil Tincture for Horses

Premium CBD for your trusty steed
cbdMD Pet CBD Oil Tincture for Horses
  • Overall Clinical Score
    99%
    Best Equine CBD Oil
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    If an apple a day keeps the doctor away, then this apple-flavored CBD can help keep your favorite equine happy between veterinary visits.

    Pro's
    Cons's
     One of the few companies that offer CBD Oil for horses  Low terpene and cannabinoid profile
     Same CBD Oil benefits as for humans  Available in single flavor only
     No THC Animal-specific products (dogs, cats, horses)
     Made from premium CBD from non-GMO USA hemp
  • Features
    Discount pricing available?15% Off Coupon Code: cbdMD15
    Source
    Source of Hemp
    Kentucky, USA
    FormOil Tincture
    IngredientsCannabidiol (CBD), MCT Oil, and Apple Flavoring
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2 extraction method
    How to take itDifferent types of horses have different physiques, so there’s no one-size-fits-all application. Usually, the best approach is to start with a lower intake every day and seeing how your horse responds, adjusting measurements as needed
    Potency
    Potency - CBD Per Bottle
    5000 mg / bottle
    Carrier OilMCT Oil
    Concentration
    CBD Concentration Per Serving
    166.67 mg per dropper (1ml)
    Drug TestNot applicable
    FlavoursApple
    Price Range$239.99
    $/mg CBD
    Price ($/mg)
    $0.05
    Shipping
    Shipping/Time to delivery
    2-5 Business days (via Fedex)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants100% organic, non-GMO, and vegan-certified
    AllergensVegan, Gluten free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedUSA only (all 50 states)
Check Latest Prices

Holista Pet CBD Oil for Horses

Fast-acting and can be given to other livestock animals
Holista Pet CBD Oil for Horses
  • Overall Clinical Score
    99%
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    HolistaPet CBD Oil for Horses is formulated with pure CO2 extracted Full Spectrum CBD Oil and Hemp Seed Oil. This creates a powerful concentration of CBD that you can easily give to your horse.

    Pro's
    Cons's
     High potency  No other flavor
     100% natural
     More affordable compared to other brands
     Can be given to other Livestock animals
  • Features
    Source
    Source of Hemp
    USA (State not specified on website)
    FormOil Tincture
    IngredientsCBD Oil, Hemp Seed Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    CO2 Extraction
    How to take itApply orally or mix with food or water
    Potency
    Potency - CBD Per Bottle
    7500mg
    Carrier OilHemp Seed Oil
    Concentration
    CBD Concentration Per Serving
    62.5mg per dropper full (1ml)
    Drug TestNot applicable
    FlavoursNone
    Price Range$294.95
    $/mg CBD
    Price ($/mg)
    $0.03
    Shipping
    Shipping/Time to delivery
    Free Economy Shipping - 1 to 5 days, Priority Mail Shipping - 2 to 3 days
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsPesticide-free
    AllergensNon-dairy and gluten-free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedUSA only except California
Check Latest Prices
Best Horse Health Support

Honest Paws CBD Oil for Horses

Helps boost your horse's immune system and cognitive health
Honest Paws CBD Oil for Horses
  • Overall Clinical Score
    99%
    Best Horse Health Support
  • Clinical Scores
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
    Perfect for...All horse breeds and sizes
  • Summary

    Give your horses the golden years they deserve by boosting their immune system and cognitive health to prevent loose lips, a rougher coat, less mentally alert, droopy fetlocks and allergies with daily dose of Honest Paws CBD Oil.

    Pro's
    Cons's
     100% natural  No other flavor
     Chemical-free  Low potency
     THC-free
  • Features
    Source
    Source of Hemp
    Colorado, USA
    FormOil Tincture
    IngredientsOrganic Full Spectrum Hemp Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    CO2 Extraction
    How to take itApply orally
    Potency
    Potency - CBD Per Bottle
    1500mg
    Carrier OilHemp Oil
    Concentration
    CBD Concentration Per Serving
    25mg per dropper full (1ml)
    Drug TestNot applicable
    FlavoursNone
    Price Range$149.95
    $/mg CBD
    Price ($/mg)
    $0.09
    Shipping
    Shipping/Time to delivery
    Standard Shipping - 2 to 6 business days, 2 Day Express Shipping via DHL or USPS
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsContaminant-free
    AllergensSoy-free and Corn-free
    Refund policyWithin 30 days
    Recommended forAll horse breeds and sizes
    Countries servedContinental United States (except California), U.S. Territories and U.S. Military Bases outside USA
Check Latest Prices

CBD Dosage for Horses

There is no exact CBD dosage standard for horses.

It is often the most challenging aspect faced by individuals who want to give CBD a try.

Many sources claim that the key to determining the proper dosage for horses is through its weight.

However, due to the lack of studies published on the equine pharmacokinetics (movement of drugs in the body) of CBD, it is impossible to estimate. 

The best course of action would be to check the product’s proper dosage instructions. The manufacturer should always provide these.

If the instructions are uncertain, consult with a veterinarian first to ensure the horse’s safety.

The best way to introduce CBD to horses is to give small doses every few days. Slowly increase only when the desired effect has been reached.

How Horses Can Take CBD Oil

Different forms of CBD products for equine administration are available on the market. 

CBD Oil Tinctures also exist for horses, with leading CBD company Canna-pet producing various products specifically for animals.

Oil Drops and Sprays are administered sublingually (under the tongue). 

Balms, on the other hand, are applied topically on the horse’s skin.

CBD Horse pellets are also among the most popular because of how easy they are to administer. Infused with CBD, individuals may feed it directly to horses.

Powders also work in the same manner. They are mixed with grain and fed to the equine mammals.

Syringes, on the other hand, may contain CBD Oil or paste and are also applied sublingually. 

Some individuals also feed CBD-infused dog treats to their horses. These take slower to take effect but are sufficient for reducing anxiety and emotional distress in horses.

Conclusion

Most of the available studies on CBD’s therapeutic properties were conducted on humans and other animals (mice, rats, pigs) subjects.

Only a few CBD studies utilize horses as subjects.

Most of the positive feedback on CBD for horses is anecdotal. However, research has shown that the ECS functions in the same manner as all mammalian life, and so may provide positive health benefits for horses as well.

There is potential in using CBD as an alternative treatment for horse’s common health issues like arthritis, laminitis, gastric ulcers, colic, and anxiety.


  1. Camposa AC, Fogac MV, Sonegoa AB, Guimarãesa FS. Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacol Res. 2016. 112: 119-27
  2. Pertwee RG. Pharmacology of Cannabinoid CB1 and CB2 Receptors. Pharmacol Ther. 1997. 74: 129-80
  3. Iffland K, Grotenhermen F.editors. European Industrial Hemp Association (EIHA) review on: Safety and Side Effects of Cannabidiol– A review of clinical data and relevant animal studies. Germany: Hürth; 2016. P.
  4. Camposa AC, Fogac MV, Sonegoa AB, Guimarãesa FS. Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacol Res. 2016. 112: 119-27
  5. Anim Genet. 2019 Dec; 50(6): 569–597. Published online 2019 Sep 30. doi: 10.1111/age.12857
  6. McCoy A.M. (2015) Animal models of osteoarthritis: comparisons and key considerations. Veterinary Pathology 52, 803–18.https://www.ncbi.nlm.nih.gov/pubmed/26063173
  7. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9561-6.
  8. Eur J Pain. 2016 Jul;20(6):936-48. doi: 10.1002/ejp.818. Epub 2015 Oct 30.
  9. Anim Genet. 2019 Dec; 50(6): 569–597. Published online 2019 Sep 30. doi: 10.1111/age.12857
  10. Pedro Sánchez-Aparicio, Benjamín Florán, Desiderio Rodríguez Velázquez, José Antonio Ibancovichi, Jorge Antonio Varela Guerrero, Sergio Recillas, Cannabinoids CB2 Receptors, One New Promising Drug Target for Chronic and Degenerative Pain Conditions in Equine Veterinary Patients, Journal of Equine Veterinary Science, Volume 85, 2020, 102880, ISSN 0737-0806, https://doi.org/10.1016/j.jevs.2019.102880.
  11. Ellis, K.L. and Contino, E.K. (2020), Treatment using cannabidiol in a horse with mechanical allodynia. Equine Vet Educ. doi:10.1111/eve.13168
  12. J Appl Anim Welf Sci. 2008;11(3):249-66. doi: 10.1080/10888700802101130.
  13. Schmidt, A., Aurich, J., Mőstl, E., Müller, J., Aurich, C., 2010. Changes in cortisol release and heart rate and heart rate variability during the initial training of 3-year-old sport horses. Hormones and Behavior 58, 628-636.
  14. Joseph Maroon, Jeff Bost. Review of the neurological benefits of phytocannabinoids. 26-Apr-2018;9:91
  15. Baker S.J., Gerring E.L. Gastric pH monitoring in healthy, suckling pony foals. Am J Vet Res. 1993;54:959–964. https://www.ncbi.nlm.nih.gov/pubmed/8323067
  16. Equine Internal Medicine. 2018 : 709–842. Published online 2017 Nov 17. doi: 10.1016/B978-0-323-44329-6.00012-7. PMCID: PMC7158344.
  17. Pertwee RG. Cannabinoids and the gastrointestinal tract. Gut 2001;48(6):859-867.
  18. Frank N., Geor R.J., Bailey S.R., Durham A.E., Johnson P.J. & American College of Veterinary Internal M. (2010) Equine metabolic syndrome. Journal of Veterinary Internal Medicine 24, 467–75.
  19. A. N. A. Verty,A. Stefanidis,A. J. McAinch,D. H. Hryciw,Brian Oldfield. Published: November 20, 2015https://doi.org/10.1371/journal.pone.0140592
  20. PLoS One. 2015; 10(11): e0140592. Published online 2015 Nov 20. doi: 10.1371/journal.pone.0140592
  21. Br J Pharmacol. 2007 Mar;150(5):613-23. Epub 2007 Jan 22.
  22. Pediatr Gastroenterol Hepatol Nutr. 2013 Sep; 16(3): 143–152. Published online 2013 Sep 30. doi: 10.5223/pghn.2013.16.3.143
  23. Grotenhermen F, Müller-Vahl K. Medicinal uses of marijuana and cannabinoids. Crit Rev Plant Sci. 2016; 35: 378–405. https://www.tandfonline.com/doi/abs/10.1080/07352689.2016.1265360
  24. Pertwee RG. Pharmacology of Cannabinoid CB1 and CB2 Receptors. Pharmacol Ther. 1997. 74: 129-80
  25. ECHO. (2017, April 18). Retrieved from https://echoconnection.org/look-endocannabinoid-systems-cb1-cb2-receptors/
  26. Camposa AC, Fogac MV, Sonegoa AB, Guimarãesa FS. Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacol Res. 2016. 112: 119-27
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