Best CBD Oil for Tiredness

Are you experiencing severe fatigue that you do not have enough energy to carry out your daily tasks? CBD Clinicals provides helpful information on how CBD may be a possible therapeutic option for your tiredness.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil

4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil

5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg

4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg

4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures

4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil

3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil

3.5 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Best CBD Oil for Candida Infection 2024

  1. Spruce 750mg Lab Grade CBD Oil Editor's Pick
  2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil Best Organic
  3. Spruce 2400mg Lab Grade CBD Oil Editor's Pick
  4. Avida Full Spectrum CBD Oil Tincture 500mg Best Seller
  5. cbdMD CBD Oil Tincture Natural 1500mg Best Natural Alternative
  6. CBDistillery THC Free CBD Oil Tinctures Best THC-Free
  7. cbdMD CBD Oil Tincture Natural 750mg Best Customer Rated
  8. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil Best Starter
  9. Hemp Bombs 750mg CBD Oil Best Flavor Range
  10. Royal CBD Full Spectrum CBD Oil Most Transparent


Compare the Best CBD Oil for Tiredness in 2024

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5
5.0 out of 5
3.5 out of 5
3.0 out of 5
5.0 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5
5.0 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5
4.5 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5
2.5 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5
4.5 out of 5
3.5 out of 5
2.5 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5
2.5 out of 5
3.5 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
1.0 out of 5
5.0 out of 5

Best CBD Oil for Tiredness

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score

4.8

CBDC Evaluation Table/Score
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Mid-strength

No other flavors

Natural peppermint flavor

Made from 100% organic and natural ingredients

Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Pure CBD hemp

No other flavors

All natural

Approximately 300 drops total

Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Extra Strength

Tastes bitter

No artificial flavoring or colors

No THC-free option

Made from 100% organic and natural ingredients

Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score

4.6

CBDC Evaluation Table/Score
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Light Spearmint flavor

No other flavor

Non-THC, Non-detected in drug test

Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score

4.7

CBDC Evaluation Table/Score
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Type

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Pros Cons

Various delicious flavors to choose from

cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options

Has vegan, organic, and gluten-free ingredients

Free shipping for this particular product within USA

World-class customer service team

Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score

4.4

CBDC Evaluation Table/Score
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Pros Cons

60-Day Satisfaction Guarantee

Dropper is a bit shaky

Various strengths

Oil extracted from aerial plant parts of US grown industrial hemp

Sourced from non-GMO industrial hemp grown in the USA through natural farming practices

Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score

4.6

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

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Pros Cons

Pure CBD hemp

No other flavors

All natural

A bit pricey compared to competitors

Approximately 100 drops total

Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score

4.4

CBDC Evaluation Table/Score
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Purity

Customer Service

Type

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Pros Cons

Vegan and Gluten free

Does not ship internationally

Has a third-party lab test

Wide variety of CBD strengths and sizes

Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score

3.9

CBDC Evaluation Table/Score
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Purity

Customer Service

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Transparency

Pros Cons

Wide variety of flavors

Incomplete information about the product

Lab test results are complete

Does not ship to all international countries

30-day money-back guarantee

Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score

3.7

CBDC Evaluation Table/Score
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Customer Service

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Transparency

Pros Cons

Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes

Shipping not specified on website

More flavors to choose from

3rd party lab result is currently not available on website

Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate

Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How We Rank
Our Ratings

How CBD May Help With Tiredness

Tiredness is different from fatigue. Usually, sleep and rest can relieve tiredness.

On the other hand, fatigue is a state of exhaustion that is often overpowering and not eased by sleep or rest(1). Fatigue that is disabling and continues for at least four months is called chronic fatigue syndrome.

Tiredness may result from psychological or physical factors, and psychological reasons for tiredness outnumber physical causes.

Psychological causes include stress, emotional shock, depression, and anxiety(2).

Chronically anxious or stressed individuals keep their bodies in overdrive. The constant adrenaline rush exhausts the body, making them fatigued or chronically tired(3).

Meanwhile, CBD may help reduce the risk of anxiety and depression(4). Data from study results show that CBD may help regulate anxiety- and depressive-related behaviors(5).

However, more extensive animal and human studies are necessary to examine CBD’s efficacy and safety for psychiatric disorders(6).

On the other hand, physical causes of tiredness include iron deficiency or anemia, sleep apnea, and underactive thyroid (hypothyroidism)(7).

When you have inadequate iron, your body cannot make enough of a component in red blood cells essential to transport oxygen (hemoglobin). Consequently, anemia caused by an iron deficiency may leave you short of breath and feel very tired(8).

CBD has little effect on iron deficiency anemia. However, hempseed oil, often used as a carrier oil in CBD products, is rich in vitamin E and minerals like iron, sulfur, calcium, phosphorus, magnesium, potassium, sodium, and zinc(9).

About 6% of the iron in your body is a component of specific proteins vital to respiration and energy metabolism(10). Thus, you need iron to combat tiredness.

Meanwhile, a night without sleep can make you feel tired the next day. Several sleepless nights can have severe mental effects like brain fog(11).

Studies noted that CBD may help with sleep problems. One crossover study comparing CBD with nitrazepam found that 160mg CBD increased sleep duration12).

Nitrazepam is a potent hypnotic drug that induces sedative and anxiolytic effects and helps with sleep problems(13).

Studies show that the drug does not worsen mild to moderate sleep apnea (sleep-disordered breathing)(14).

CBD and the Endocannabinoid System

Every mammal, including humans, has an endocannabinoid system (ECS) responsible for sustaining numerous body processes.

There are two primary receptors in the endocannabinoid system, CB1 and CB2, with distinct functions(15).

Pain perception, mood, sleep, hunger, memory, and motor control are all influenced by CB1 cannabinoid receptors(16).

On the other hand, CB2 receptors are found chiefly on immune system cells in the human body. They induce an anti-inflammatory response, reducing chronic pain and tissue damage(17).

With a low binding affinity for CB2 and CB1 receptors, CBD may reduce the psychoactive effects of THC while maintaining body balance or homeostasis(18).

Researchers noted that cannabidiol (CBD) prevents the degradation of the endocannabinoid system by directly stimulating cannabinoid receptors(19).

The whole-plant cannabidiol, a natural substance found in Cannabis sativa and generated from Cannabaceae plants, is a cannabinoid prevalent in the hemp family.

Hemp is a cannabis plant with less than 0.3% THC (tetrahydrocannabinol) concentration(20). Meanwhile, marijuana plants of the Cannabissativa and the Cannabisindica species are rich in THC.

Medical marijuana (also called medical cannabis) is a term used to describe derivatives of the Cannabissativa plant that may ease symptoms caused by specific medical conditions(21).

The FDA  or the U.S. Food and Drug Administration has not approved the use of cannabis (marijuana) to cure any medical condition(22).

However, the FDA has approved the use of a cannabidiol-based drug (Epidiolex) and dronabinol (Marinol, Syndros)(23).

Epidiolex is used for the treatment of severe forms of epilepsy(24).  Dronabinol is a man-made form of cannabis to treat loss of appetite(25).

Benefits of Using CBD for Tiredness

CBD may relieve some of the tiredness’s psychological and physical causes, such as anxiety and sleep apnea.

CBD for Anxiety Disorder

Studies suggested that CBD may help manage anxiety disorder symptoms(26). Unlike 9-tetrahydrocannabinol (THC), cannabidiol does not have psychoactive effects on the central nervous system(27).

However, there is a need for more longitudinal studies to determine whether medical marijuana, with cannabinoids CBD and THC, may help treat depression and anxiety.

CBD has also been known for its anti-inflammatory properties that may help alleviate symptoms of various diseases caused by oxidative stress(28).

The accumulation of oxygen-reactive species in tissues and cells can damage tissue and result in cell death. This process has been linked to the development of neurological disorders, such as anxiety disorders(29).

Results of studies involving oxidative stress in tiredness are essential in present and future animal and human studies.

In addition, studies on the antioxidant and anti-inflammatory properties of CBD(30) may explain how CBD may help with oxidative stress. Researchers have suggested that cannabidiol may help protect various proteins and lipids from damage(31).

However, more relevant studies are needed to confirm the effectiveness of CBD in the treatment of neurodevelopmental conditions, such as anxiety disorder.

CBD for Sleep Apnea

Sleep apnea is a collection of respiratory problems characterized by snoring, headaches, sleep disturbances (insomnia), and daytime tiredness(32). Patients with the condition may experience sleep deprivation or have less than optimal sleep.

Researchers noted that a Sativex extract formulation containing equal doses of CBD and THC may improve sleep quality in subjects with cancer and neuropathic pain(33). Results also suggest that cannabis derivatives may also help with chronic pain and fibromyalgia.

There have been mixed effects when combining CBD and THC. The study showed that combining the two compounds may improve sleep quality(34).

Studies have shown that cannabidiol may help individuals sleep better(35). Still, further studies are needed to determine how CBD may help with sleep disorders.

Can CBD Help Sustain Focus and Energy?

Studies have suggested that CBD may alter proinflammatory pathways and energy metabolism in vitro(36). However,  there is a need for further human clinical studies to assess whether CBD may help increase focus and energy.

While CBD oil may provide potential health benefits, studies have not found sufficient evidence supporting its claims. For your safety, consult a healthcare expert before taking CBD for any medical condition, including tiredness.

How Long Does CBD Take to Help With Tiredness?

CBD oil, through sublingual administration, may allow users to experience its effects in 15 to 30 minutes(37).

On the other hand, CBD edibles like gummies may take effect as soon as 30 minutes to two hours after consuming them.

Meanwhile, inhaling CBD through vaping or smoking may have a two-minute onset time, depending on the method of administration(38).

How Long Does CBD Help With Tiredness?

CBD’s effects depend on the compound’s bioavailability and half-life.

The half-life of a medication is the time required to decrease it to half its original dosage. For instance, cannabidiol can last for about 1.4 to 10.9 hours after administration using an oromucosal spray(39).

Meanwhile, bioavailability is the property of a drug or other substance that allows it to be absorbed and used by the body. Bioavailability depends on the product’s composition and the route of administration.

For instance, CBD has a 31% bioavailability after smoking(40). On the other hand, CBD has a bioavailability of between 6% and 20% when taken sublingually.

How to Take CBD Oil for Tiredness

One convenient and direct way to take the best CBD oil is by consuming CBD capsules and edibles. These products ensure that the CBD dosage is consistent.

Using droppers to consume cannabidiol oil or tinctures is a practical option for users wanting to control their dosage. These products may be administered sublingually (directly under the tongue), enabling the compound to be absorbed into the bloodstream through the tissues beneath the tongue.

A study conducted in 2010 supported this concept, stating that the peak blood levels of most drugs commonly used in the field of sublingual application are achieved in about 10 to 15 minutes(41).

When choosing the right amount of CBD for specific medical conditions, talk to the healthcare provider about your options and preferences.

CBD Dosage for Tiredness

There is no standard CBD dosage for tiredness. Generally, dosage ranges for CBD uses take into consideration the patient’s body weight to help determine the ideal starting dose(42).

According to research, low doses are modest levels, ranging from 0.5 mg to 20 mg of CBD per dosage per day(43).

How to Choose the Best CBD Oil for Tiredness

CBD tinctures, topical CBD products like lotions and creams, edibles like CBD gummies, pills, and capsules, and CBD vapes are only some of the various CBD products available on the market.

These products may contain full-spectrum CBD, broad-spectrum CBD, or CBD isolates.

Broad- or full-spectrum extracts from whole plants are also called whole-plant products or whole plant CBD products.

These products contain all the beneficial components found in the natural plant. However, unlike full-spectrum CBD oils, broad-spectrum CBD oils are THC-free.

Meanwhile, CBD isolates only contain pure CBD.

Note that hemp oil (a term also used to refer to CBD oil) and hemp seed oil are not the same.

Although hempseed oil contains nutrients and fatty acids, it does not have the same properties as full-spectrum CBD oil extracted from hemp flowers, leaves, and stalks(44).

To ensure that beginners (first-time users) and experienced CBD users are buying high-quality products, they should:

  • Choose organic hemp and locally-grown hemp extract from hemp farms that practice sustainable farming. Also, look for CBD products made with USDA-certified organic ingredients.
  • Consider the extraction method used. Steam distillation, ethanol, natural solvent, and CO2 extraction methods are some of the safe and clean extraction methods used by manufacturers.
  • Look for a trusted company that uses high-quality CBD extract. Verify the oil’s potency and purity by looking at the certificate of analysis (COA) from a third-party lab.

COAs ensure that the CBD brands’ products contain non-GMO ingredients, without heavy metals, pesticides, and molds that can compromise customers’ wellness.

  • Buy wellness products like CBD supplements loaded with omega-3 fatty acids, which may help relieve stress and promote sleep(45). These products may help with tiredness.
  • Try to purchase products from companies that offer a money-back guarantee to their customers. CBD brands like Charlotte’s Web, CBDistillery, and Nuleaf Naturals aim to provide customer satisfaction by adding this feature.

Side Effects of Using CBD for Tiredness

CBD may cause mild to moderate side effects, such as diarrhea, dry mouth, reduced appetite, fatigue, and drowsiness(46).

However, the entourage effect gives a favorable contribution of terpenes to cannabinoids to improve the cannabinoids’ health benefits(47).

A study shows that smaller doses of CBD were stimulating, whereas more significant amounts were found to be relaxing(48).

Based on over 130 studies, CBD does not affect physiological parameters, including blood pressure, heart rate, and body temperature. Hence, CBD may be safe for chronic fatigue syndrome or CFS symptoms(49).

Legality of CBD

At the federal state level, marijuana remains a controlled substance under the Federal Controlled Substances Act. The Drug Enforcement Administration noted a high abuse potential(50).

The FDA has only approved Epidiolex, a CBD-based medicine for tubular sclerosis and seizures associated with two pediatric epilepsy types(51).

Meanwhile, the 2018 Farm Bill allowed CBD products to be sold in the United States if they contained less than 0.3% THC.

However, each state has their regulations regarding the level of THC(52). For example, in Indiana, Governor Eric Holcomb signed a bill that allows the sale of low-THC hemp extract(53).

Product Frequently
Asked Questions

  • How can CBD help with tiredness?

    CBD’s anti-inflammatory characteristics may help with oxidative stress-induced causes of tiredness, such as anxiety disorder(54).

  • What evidence or research exists to say that CBD helps with tiredness?

    Sativex, formulated with equal doses of CBD and THC, may improve sleep quality in individuals with chronic pain(55). Pain and fatigue had been linked to sleep disorders(56).

    Medically speaking, fatigue is overwhelming tiredness not often relieved by sleep(57).

  • Is there any evidence that CBD can make tiredness worse?

    CBD is well tolerated. Still, it can cause fatigue, diarrhea, reduced appetite,  dry mouth, and drowsiness(58). Thus, there is a possibility that CBD can make tiredness worse.

  • Will CBD interact with any current medication I may be taking for tiredness?

    CBD is not a chemical that is inert to biological processes. As a result, it may potentially interact with other compounds(59).

  • Are there other treatments I should consider alongside CBD to help with tiredness?

    Your doctor may recommend medications or therapy(60) to manage excessive tiredness. Nevertheless, you should consult your doctor if you consider using CBD in conjunction with other therapies for tiredness.

  • Can I fail a drug test if I use CBD for tiredness?

    When consumed regularly over four to six days, full-spectrum CBD products may include trace levels of THC, which may accumulate in the body(61). A higher amount of THC in the bloodstream may result in a positive drug test(62).

  • What is the dosage for tiredness?

    For optimal results, the ideal starting dose should be taken into account with the patient’s weight. For instance, a 20-microdose dose can be given daily(63).

  • Are there any side effects of CBD oil for tiredness?

    While CBD may effectively alleviate the symptoms of extreme sleepiness, it may also induce adverse effects, such as dry mouth, nausea, and headaches(64).

  • Is CBD oil safe for tiredness?

    A thorough evaluation of over 130 research found that CBD has no impact on physiological markers, such as blood pressure and body temperature(65).

  • Is CBD oil for tiredness legal?

    The 2018 Farm Bill allows CBD products with less than 0.3% THC concentration to be marketed in the U.S. However, different state laws have different regulations(66).

1. 10 medical reasons for feeling tired
https://www.nhs.uk/live-well/sleep-and-tiredness/10-medical-reasons-for-feeling-tired/

2. Sleep and tiredness
https://www.nhs.uk/live-well/sleep-and-tiredness/

3. Fatigue
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/fatigue

4. Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699613/

5. Ibid.

6. Ibid.

7. Sleep and tiredness
https://www.nhs.uk/live-well/sleep-and-tiredness/

8. Iron deficiency anemia
https://www.mayoclinic.org/diseases-conditions/iron-deficiency-anemia/symptoms-causes/syc-20355034

9. Nutritive quality of romanian hemp varieties (Cannabis sativa L.) with special focus on oil and metal contents of seeds
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543203/

10. Hemoglobin and Functions of Iron
https://www.ucsfhealth.org/education/hemoglobin-and-functions-of-iron

11. Why lack of sleep is bad for your health
https://www.nhs.uk/live-well/sleep-and-tiredness/why-lack-of-sleep-is-bad-for-your-health/

12. Cannabidiol in Anxiety and Sleep: A Large Case Series
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/

13. Nitrazepam
https://go.drugbank.com/drugs/DB01595

14. Nitrazepam in patients with sleep apnoea: a double-blind placebo-controlled study
https://pubmed.ncbi.nlm.nih.gov/7875274/

15. An introduction to the endogenous cannabinoid system
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789136/

16. Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430692/

17. The CB2 receptor and its role as a regulator of inflammation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075023/

18. Ibid.

19. Ibid.

20. Cannabidiol
https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol

21. Medical marijuana
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/medical-marijuana/art-20137855

22. Ibid.

23. Ibid.

24. FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy
https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms

25. Dronabinol
https://www.drugs.com/mtm/dronabinol.html.

26. Cannabidiol as a Potential Treatment for Anxiety Disorders
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4604171/

27. Ibid.

28. Chronic fatigue syndrome: oxidative stress and dietary modifications
https://pubmed.ncbi.nlm.nih.gov/11703165/#:~:text

29. Oxidative Stress and the Central Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193071/

30. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#

31. Ibid.

32. Sleep Apnea
https://my.clevelandclinic.org/health/diseases/8718-sleep-apnea

33. Cannabinoids in the management of difficult to treat pain
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2503660/

34. Cannabinoids, Endocannabinoids and Sleep
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388834/

35. Ibid.

36. Glial Cells and Their Contribution to the Mechanisms of Action of Cannabidiol in Neuropsychiatric Disorders
https://www.frontiersin.org/articles/10.3389/fphar.2020.618065/full

37. Using CBD for Arthritis: Tips for How to Get Started
https://creakyjoints.org/alternative-medicine/how-to-take-cbd-for-arthritis/.

38. Can vaping damage your lungs? What we do (and don’t) know
https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734

39. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/

40. Healing With CBD, page 192.
https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view

41. SUBLINGUAL MUCOSA AS A ROUTE FOR SYSTEMIC DRUG DELIVERY Hemp
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1092.pdf

42. CBD: A Patient’s Guide to Medicinal Cannabis.
https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view

43. Ibid.

44. Hemp
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/hemp

45. Higher levels of omega-3 in diet are associated with better sleep, study shows
https://www.sciencedaily.com/releases/2014/03/140306103931.htm

46. What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700

47. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage Effects
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3165946/

48. Cannabidiol as a Potential Treatment for Anxiety Disorders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/

49. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical
Data and Relevant Animal Studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

50. The Science behind the DEA’s Long War on Marijuana
https://www.scientificamerican.com/article/the-science-behind-the-dea-s-long-war-on-marijuana/

51. FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy
https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms

52. The Farm Bill, hemp legalization and the status of CBD: An explainer
https://www.brookings.edu/blog/fixgov/2018/12/14/the-farm-bill-hemp-and-cbd-explainer/

53. Gov. Holcomb signs bill legalizing low-THC CBD oil
https://www.mpp.org/states/indiana/#:~:text=On%20March%2021%2C%202018%2C%20Gov,more%20than%200.3%20percent%20THC.

54. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#

55. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#

56. The relationship between pain, fatigue, sleep disorders and quality of life in adult patients with acute leukaemia: During the first year after diagnosis
https://pubmed.ncbi.nlm.nih.gov/28913954/#:~:text=It%20was%20found%20that%20pain,001).

57. 10 medical reasons for feeling tired
https://www.nhs.uk/live-well/sleep-and-tiredness/10-medical-reasons-for-feeling-tired/

58. What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700

59. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/

60. Chronic fatigue syndrome
https://www.mayoclinic.org/diseases-conditions/chronic-fatigue-syndrome/diagnosis-treatment/drc-20360510

61. Can You Take CBD and Pass a Drug Test?
https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/

62. Cannabinoid Screen and Confirmation (Urine)
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=cannabinoid_screen_urine

63. CBD: A Patient’s Guide to Medicinal Cannabis.
https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view

64. What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700

65. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

66. The Farm Bill, hemp legalization and the status of CBD: An explainer
https://www.brookings.edu/blog/fixgov/2018/12/14/the-farm-bill-hemp-and-CBD-explainer/

 


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