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Best CBD Oil for Toothache

Is your tooth causing throbbing pain? Are you looking for an alternative remedy to help with toothache? This article discusses how CBD oil may help manage toothache and other dental problems related to this condition.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Compare the best CBD for Toothache in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5

Best CBD Oil for Toothache

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How CBD Helps With Toothache

Cannabidiol (CBD) is one of several compounds extracted from the cannabis plant known to produce antibacterial effects(1). Studies also showed CBD’s analgesic, antimicrobial, anxiolytic (anti-anxiety), and anti-inflammatory properties(2).

CBD works by engaging the cannabinoid receptors in the body’s endocannabinoid system (ECS).

The ECS is present in the nervous and immune systems. It regulates various physiological processes and maintains internal homeostasis and wellness.

CBD’s therapeutic benefits may help manage various tooth conditions related to toothaches, such as burning mouth syndrome, gingivitis, and dental anxiety(3).

Toothache is pain felt in or around the tooth. The pulp inside the tooth contains sensitive nerves, blood vessels, and tissues. When the pulp is irritated or infected by bacteria, severe nerve pain and pulpitis or dental pulp inflammation may follow.

There are several possible causes of toothache, such as(4):

  • Tooth decay
  • Tooth abscess
  • Fractured tooth
  • Repetitive motions like bruxism (teeth grinding)
  • Gum disease
  • Tooth eruption or removal
  • Damaged filling

Individuals experiencing toothache may feel sharp, throbbing, or constant tooth pain. Toothaches may also cause swelling around the tooth, bad mouth odor, foul taste from the aching tooth, headache, or fever(5).

Dentists can diagnose toothaches by determining the location of the pain, when the pain started, its severity, what makes the pain worse, and what provides relief.

A physical exam is conducted by checking the areas in and around your mouth, such as your teeth, gums, tongue, jaw, sinuses, and throat. The exam may also include your ears, nose, and neck.

Some alternative remedies to help relieve toothache include cold compress, saltwater rinse, hydrogen peroxide solution, and non-steroidal anti-inflammatory drugs (NSAIDs)(6).

Natural remedies like vanilla extract have antioxidants, and clove oil may also be used as an antiseptic for pain relief(7).

Baking soda may also be used as toothpaste. A 2009 study suggested baking soda may be better than regular toothpaste in managing dentinal sensitivity(8).

Uses and Benefits of CBD Oil for Toothache

The analgesic properties of cannabinoids like CBD suggest that the compound may help relieve pain caused by toothaches. These same properties may also help manage pain brought by tooth extractions and postoperative pain management(9).

A 2021 study evaluated the suitability and efficiency of Cannabis sativa oil on patients with burning mouth syndrome (BMS)(10). BMS is a burning sensation in the tongue, lips, gums, or the whole mouth.

The study showed that Cannabis sativa oil may help provide significant clinical remission over time of oral symptoms brought by BMS.

Additionally, cannabis oil may help provide a favorable improvement on anxiety and depression levels due to BMS(11). In the same study, the patients did not experience adverse effects that might cause them to stop taking cannabis oil.

Researchers investigated the therapeutic effects of CBD in addressing dental anxiety. A 2021 report mentioned 15mg to 30mg of CBD administered sublingually preparatory to a dental appointment may help manage dental pain and anxiety(12).

Cannabinoids like CBD and tetrahydrocannabinol (THC) may also help address periodontal disease or gum infection(13).

These cannabinoids provide anti-inflammatory and analgesic effects that may help manage chronic pain brought by periodontal disease(14). This disease includes gingivitis (early stage) and periodontitis (advanced stage).

CBD Dosage for Toothache

While there is no specific dosage for toothache approved by the FDA, people taking CBD may initially ingest lower doses(15).

One report stated that 15-30 milligrams of CBD oil taken sublingually may be helpful for dental anxiety and dental pain(16).

CBD dosage may vary among individuals. Determining how much CBD to take may depend on factors like health conditions, exercise, stress levels, diet, and genetics(17).

Consult your dentist about your dental condition and oral health before considering CBD for managing toothache.

How to Take CBD Oil for Toothache

CBD oil may be taken using different methods.

  • Sublingual administration delivers drops of CBD oil directly into the bloodstream, bypassing the digestive tract. Droppers or oromucosal sprays are standard methods to administer CBD sublingually or under the tongue.

CBD oil tinctures are usually diluted with a carrier oil, such as coconut oil or hemp oil (particularly hempseed oil).

  • CBD administered orally passes through the digestive tract before being carried into the bloodstream.

Some products taken orally include CBD capsules and edibles. Examples of edibles are gummies and candies.

  • CBD topicals like toothpaste or mouthwash are used to target the affected area in the mouth.
  • Vaping involves administering CBD by inhalation. Vaping may be considered the fastest way to deliver CBD into the body(18).

However, vaping has potential health risks associated with lung disease(19). Individuals with dental health problems must consult with their dentist before vaping or smoking CBD.

How Long Does CBD Take to Help With Toothache?

Currently, there is no specific study on onset times for CBD for toothache.

CBD onset times vary depending on the type of product, dosage, method of use, frequency of intake, and the individual’s overall health condition.

How Long Will CBD Help With Toothache?

There are currently no studies determining the duration of the effects of CBD for toothache.

A 2018 review in Frontiers of Pharmacology mentioned that CBD oromucosal sprays at 5mg to 20mg doses may have a half-life of around 1.4 and 10.9 hours(20).

Half-life is the duration for a drug to reduce its concentration or quantity in the body by 50%.

Risks and Side Effects of Using CBD for Toothache

CBD may cause several side effects well tolerated among humans, such as dry mouth, fatigue, appetite loss, drowsiness, and diarrhea(21).

Some CBD products come with a grapefruit warning on their labels. This warning means CBD may interfere with other drugs and prevent them from breaking down and being absorbed by the body.

Grapefruit juice may block the CYP3A4 enzymes needed to metabolize drugs, which may cause the medication to remain longer in the body instead of being absorbed and taking effect(22).

The severity of effects caused by the interaction of CBD and other medications can vary depending on the drug, the amount of grapefruit juice consumed, or the amount of CYP3A4 enzymes in a person’s intestines.

How to Choose the Right CBD for Toothache

Choosing the best CBD oil to help address toothache includes considering what extraction methods and the types of CBD products may work best for you.

High-quality CBD oil is extracted from the cannabis plant using CO2 (carbon dioxide), hydrocarbon, or ethanol extraction methods.

After the extraction process, CBD oil may be marketed as full-spectrum, broad-spectrum, or isolates.

Full-spectrum CBD oil has all the cannabinoids and compounds from the cannabis plant, including THC, terpenes, and flavonoids.

Combining these compounds creates an “entourage effect” wherein cannabinoids and other compounds work synergistically to enhance the purported health benefits of cannabis(23).

Broad-spectrum CBD oils contain most of the cannabinoids present in full-spectrum CBD oil except for THC. Individuals who prefer CBD without the psychoactive effects of THC may consider broad-spectrum CBD as a viable option.

Isolates contain pure CBD only. No other cannabinoids or compounds are included in this product.

Legality of CBD

The 2018 Farm Bill removed hemp-based CBD products from the Drug Enforcement Administration’s controlled substances list and legalized the cultivation of industrial hemp.

CBD products and supplements that contain more than 0.3% THC are prohibited under federal law(24).

The legal use of CBD may vary among states. Review your state’s laws and check your CBD product’s THC content to determine whether using CBD is legal in your area.

Product Frequently
Asked Questions

  • How can CBD help with toothache?

    CBD has analgesic, anti-anxiety, antimicrobial, and anti-inflammatory properties that may manage pain and inflammation associated with various tooth conditions related to toothache(25).

  • What evidence or research exists to say that CBD helps with toothache?

    There are currently no specific studies to determine whether CBD can help with toothaches. However, A 2021 study mentioned that cannabinoids like THC and CBD have analgesic properties that may help relieve pain caused by toothaches(26).

  • Is there any evidence that CBD can make toothaches worse?

    To date, no studies have been conducted specifically to determine if CBD worsens toothache.

    However, CBD may cause side effects, such as dry mouth, fatigue, appetite loss, drowsiness, and diarrhea(27).

  • Will CBD interact with any current medication I may be taking for toothaches?

    CBD may interact with other medications. If you are currently taking toothache medications, consult a pharmacist or dentist to know if your prescription may be affected.

    CBD products usually come with a grapefruit warning, meaning CBD may interfere with the effects of other medicines.

  • Are there other treatments I should consider alongside CBD to help with toothaches?

    Natural remedies like vanilla extract and clove oil may serve as painkillers(28). Baking soda may also be used as toothpaste for managing dentinal sensitivity(29).

    The purported benefits these natural compounds possess may be the reason some manufacturers of CBD toothpaste and CBD mouthwash include vanilla extract, clove oil, or baking soda in their products.

  • Can I fail a drug test if I use CBD for toothaches?

    Taking CBD products containing less than 0.3% THC usually does not cause a drug test failure. However, the regular use of CBD oil containing THC may cause THC levels to increase(30).

  • What is the dosage for toothaches?

    There is currently no FDA-approved CBD dosage for toothache.

    However, a 2021 study mentioned that a 15-30mg sublingual dose of CBD oil may help address dental anxiety and dental pain(31).

  • Can I put CBD oil on a toothache?

    To date, there has been no study mentioning that putting CBD oil on a tooth may help alleviate toothache.

    However, oral-based CBD topicals like toothpaste or mouthwash may be used to target the affected areas in the mouth.CBD’s anti-inflammatory and analgesic properties may help manage toothache(32).


  1. Antibacterial activity of Δ9-tetrahydrocannabinol and cannabidiol
    https://realmofcaring.org/wp-content/uploads/2020/12/Antibacterial-activity-of-D9_tetrahydrocannabinol-and-cannabidiol.pdf
  2. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  3. Ibid.
  4. Toothache
    https://my.clevelandclinic.org/health/diseases/10957-toothache
  5. Ibid.
  6. Toothache: Causes, symptoms, treatment, and prevention
    https://my.clevelandclinic.org/health/diseases/10957-toothache
  7. Ibid.
  8. Effectiveness of a baking soda toothpaste delivering calcium and phosphate in reducing dentinal hypersensitivity
    https://pubmed.ncbi.nlm.nih.gov/20128316/
  9. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  10. Evaluating the Suitability and Potential Efficiency of Cannabis sativa Oil for Patients with Primary Burning Mouth Syndrome: A Prospective, Open-Label, Single-Arm Pilot Study
    https://doi.org/10.1093/pm/pnaa318
  11. Ibid.
  12. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  13. Ibid.
  14. Ibid.
  15. CBD dosing
    https://www.projectcbd.org/guidance/cbd-dosing
  16. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  17. CBD dosing
    https://www.projectcbd.org/guidance/cbd-dosing
  18. Best way to take CBD
    https://www.projectcbd.org/guidance/best-way-take-cbd
  19. Can vaping damage your lungs? What we do (and don’t) know
    https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  20. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://doi.org/10.3389/fphar.2018.01365
  21. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  22. Grapefruit Juice and Some Drugs Don’t Mix
    https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix
  23. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  24. CBD & THC: Myths and misconceptions
    https://www.projectcbd.org/cbd-101/cbd-misconceptions
  25. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  26. Ibid.
  27. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  28. Toothache: Causes, symptoms, treatment, and prevention
    https://my.clevelandclinic.org/health/diseases/10957-toothache
  29. Effectiveness of a baking soda toothpaste delivering calcium and phosphate in reducing dentinal hypersensitivity
    https://pubmed.ncbi.nlm.nih.gov/20128316/
  30. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  31. The Current and Potential Application of Medicinal Cannabis Products in Dentistry
    https://doi.org/10.3390/dj9090106
  32. Ibid.
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