Can CBD Be Taken With Alcohol? Can CBD Help Curb Alcoholism?

Alcohol is a drug categorized as a depressant, according to the Alcohol and Drug Foundation (ADF)(1). Alcohol impacts the central nervous system (CNS), slowing down the messages between the brain and the body. 

Alcohol can also affect coordination and concentration, slowing down one’s ability to respond to unexpected situations. 

In small doses, alcohol can cause an individual to feel more relaxed and less inhibited. In larger doses, it can cause drowsiness, vomiting, unconsciousness, and death(2).

CBD and Alcohol Interaction

CBD (cannabidiol) is non-psychoactive, making it favorable to those who want to experience the health benefits of cannabis plants without the high induced by tetrahydrocannabinol (THC). 

A level of about 1% THC is generally considered the threshold for cannabis to have an intoxicating effect(3).

With the rise of alcoholic beverages, like CBD-infused beers and cocktails, it is essential to examine whether or not mixing CBD oil and alcohol is safe and whether it is beneficial or detrimental to health.

A clinical trial published in the Psychopharmacology journal examined ten volunteers under the influence of placebo, CBD, alcohol, and CBD mixed with alcohol(4).

The researchers found that the consumption of CBD and alcohol together resulted in significantly lower blood alcohol levels compared to that of alcohol consumption alone. 

Meanwhile, significant impairments in both motor (muscle movement) and psychomotor (mentally-conscious movement) performance, regardless of CBD intake, were noted.

The results of the study suggested that the reduced level of alcohol in the blood when taking CBD was an indication that CBD can alter the process of alcohol metabolism. 

This impact was confirmed by a study published in Reviews on Environmental Health which demonstrated that cannabinoids might affect the enzymes responsible for metabolizing alcohol(5).

Long-Term Health Risks of Excessive Alcohol Use

In an article on alcohol use disorder, Mayo Clinic explains that alcoholism is a physical and emotional dependence on alcohol(6). 

Over time, excessive alcohol use can result in the development of chronic diseases and other severe problems, including:

  • High blood pressure, stroke, heart disease, digestive problems, and liver disease, such as fatty liver disease(7);
  • Cancer of the breast, throat, mouth, esophagus, liver, and colon(8);
  • Learning and memory problems, such as dementia and poor school performance(9);
  • Mental health problems, including depression and anxiety(10);
  • Social problems, including lost productivity, family problems, and unemployment(11);
  • Alcohol dependence or alcoholism(12).

Excessive alcohol use or excessive drinking includes binge drinking, heavy drinking, and any drinking by pregnant women or people younger than age 21(13). 

How CBD May Help Curb Alcoholism

CBD can function as an antioxidant while also preventing the alcohol-induced decrease in self-detox processes.

A 2014 review published in the Free Radical Biology and Medicine journal demonstrated that CBD protected the liver of animal subjects from binge alcohol-induced steatosis (fatty liver) by reducing oxidative stress and by increasing the autophagy self-detox process(14). 

Autophagy is the body’s way of cleaning out damaged cells to regenerate newer, healthier cells.

Prolonged exposure to alcohol, together with genetic factors, may also lead to irregularities in the functioning of the endocannabinoid system (ECS), which in turn can lead to addictive behavior. 

A study published in the Alcohol journal showed that CB1 receptors play a significant role in the reinforcing and motivating attributes of alcohol(15).

Research showed that CBD might help individuals overcome addictive behaviors, such as alcoholism.

In a 2017 study published in Addiction Biology, results indicated that the administration of CBD reduced the reinforcing properties, motivation, and relapse for alcohol in animal subjects(16). In addition, the authors proposed CBD as a potentially useful treatment of alcohol use disorders.

A review in the Neurotoxicity Research journal presented several studies focused on the effects of cannabinoids during chronic alcohol consumption(17).

Results of the preclinical animal studies suggested that THC encouraged alcohol consumption, while CBD reduced alcohol consumption.

THC, or tetrahydrocannabinol, is known to have an affinity for the CB1 receptors, whereas CBD is a CB1 receptor antagonist. 

An antagonist is a component that prevents or weakens a biological reaction. Upon binding to the receptor, it does not activate.

Results of another study, which was published in the Experimental and Clinical Psychopharmacology in 2019, also suggested CBD could attenuate alcohol consumption and potentially protect against specific harmful effects of alcohol(18).

Conclusion

The consumption of CBD and alcohol together resulted in significantly lower alcohol levels in the blood compared to taking alcohol alone. 

Preliminary research demonstrates CBD decreases alcohol consumption and generally reduces the motivation and relapse for alcohol. 

However, there has been no study that indicates the specific dosage of CBD to curb alcoholism. Neither is there a study that recommends explicitly taking CBD oil or tincture with alcohol.

While the long-term effects of alcohol taken in excess may include the development of chronic diseases, the long-term side effects of CBD use are still unknown.

Further longitudinal studies are needed to understand how CBD may help with alcoholism fully. 

Always consult with a doctor experienced in cannabis use before deciding to mix CBD products and alcohol or using CBD products to help with alcoholism or alcohol addiction. 


  1. ADF. (2020, Jan 28). What are depressants? Retrieved from https://adf.org.au/drug-facts/depressants/.
  2. Ibid. 
  3. E. Small and D. Marcus, “Hemp: A New Crop with New Uses for North America,” in Trends in New Crops and New Uses, ed. J. Janick and A. Whipkey (Alexandria, VA: American Society for Horticultural Science Press, 2002.
  4. Consroe P, Carlini EA, Zwicker AP, Lacerda LA. Interaction of cannabidiol and alcohol in humans. Psychopharmacology (Berl). 1979;66(1):45–50. doi:10.1007/bf00431988. 
  5. Marselos M, Vasiliou V, Malamas M, Alikaridis F, Kefalas T. Effects of cannabis and tobacco on the enzymes of alcohol metabolism in the rat. Rev Environ Health. 1991;9(1):31–37. doi:10.1515/reveh.1991.9.1.31.
  6. Mayo Clinic. (2018, July 11). Alcohol use disorder. Retrieved from https://www.mayoclinic.org/diseases-conditions/alcohol-use-disorder/symptoms-causes/syc-20369243.
  7. World Health Organization. Global status report on alcohol and health—2014. Geneva, Switzerland: World Health Organization; 2014; Rehm J, Baliunas D, Borges GL, Graham K, Irving H, Kehoe T, et al. The relation between different dimensions of alcohol consumption and burden of disease: an overview. Addiction. 2010;105(5):817-43.
  8. World Health Organization. Global status report on alcohol and health—2014. Geneva, Switzerland: World Health Organization; 2014; International Agency for Research on Cancer. Personal Habits and Indoor Combustions: A Review of Human Carcinogens, Volume 100E 2012. Available from: http://monographs.iarc.fr/ENG/Monographs/vol100E/index.php.
  9. World Health Organization. Global status report on alcohol and health—2014. Geneva, Switzerland: World Health Organization; 2014; Miller JW, Naimi TS, Brewer RD, Jones SE. Binge drinking and associated health risk behaviors among high school students. Pediatrics. 2007;119(1):76-85.
  10. World Health Organization. Global status report on alcohol and health—2014. Geneva, Switzerland: World Health Organization; 2014; Castaneda R, Sussman N, Westreich L, Levy R, O’Malley M. A review of the effects of moderate alcohol intake on the treatment of anxiety and mood disorders. J Clin Psychiatry 1996;57(5):207–212.
  11. World Health Organization. Global status report on alcohol and health—2014. Geneva, Switzerland: World Health Organization; 2014; Booth BM, Feng W. The impact of drinking and drinking consequences on short-term employment outcomes in at-risk drinkers in six southern states. J Behavioral Health Services and Research 2002;29(2):157–166; Leonard KE, Rothbard JC. Alcohol and the marriage effect. J Stud Alcohol Suppl 1999;13:139–146.
  12. Esser MB, Hedden SL, Kanny D, Brewer RD, Gfroerer JC, Naimi TS. Prevalence of Alcohol Dependence Among US Adult Drinkers, 2009–2011. Prev Chronic Dis 2014;11:140329.
  13. Centers for Disease Control and Prevention (CDC). (2019, Dec.30). What is Excessive Alcohol Use? Retrieved from https://www.cdc.gov/alcohol/onlinemedia/infographics/excessive-alcohol-use.html.
  14. Yang L, Rozenfeld R, Wu D, Devi LA, Zhang Z, Cederbaum A. Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy. Free Radic Biol Med. 2014;68:260–267. DOI:10.1016/j.freeradbiomed.2013.12.026.
  15. Pava MJ, Woodward JJ. A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research. Alcohol. 2012;46(3):185–204. DOI:10.1016/j.alcohol.2012.01.002.
  16. Viudez-Martínez A, García-Gutiérrez MS, Navarrón CM, et al. Cannabidiol reduces ethanol consumption, motivation and relapse in mice. Addict Biol. 2018;23(1):154–164. DOI:10.1111/adb.12495.
  17. Kleczkowska P, Smaga I, Filip M, Bujalska-Zadrozny M. Cannabinoid Ligands and Alcohol Addiction: A Promising Therapeutic Tool or a Humbug?. Neurotox Res. 2016;29(1):173–196. DOI:10.1007/s12640-015-9555-7.
  18. Nona, C. N., Hendershot, C. S., & Le Foll, B. (2019). Effects of cannabidiol on alcohol-related outcomes: A review of preclinical and human research. Experimental and Clinical Psychopharmacology, 27(4), 359–369. https://doi.org/10.1037/pha0000272

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DISULFIRAM ICSC: 1438

Date of Peer Review: October 2002

Tetraethylthiuramdisulfide 1,1′-Dithiobis(N,N-diethylthioformamide) bis-(N,N-Diethylthiocarbamoyl)disulfide TETD

CAS # 97-77-8 C10H20N2S4 / ((C2H5)2NCS)2S2 RTECS # JO1225000 Molecular mass: 269.6 UN #

EC # 006-079-00-8

TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING FIRE Combustible. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).

EXPOSURE

PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!

Inhalation

Ventilation, local exhaust, or breathing protection.

Skin

Protective gloves. Rinse skin with plenty of water or shower. Eyes

Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. Ingestion Confusion. Headache. Nausea. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.

SPILLAGE DISPOSAL PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Do NOT let this chemical enter the environment. Personal protection: P2 filter respirator for harmful particles. EU Classification Symbol: Xn, N R: 22-43-48/22-50/53 S: (2-)-24-37-60-61 UN Classification

EMERGENCY RESPONSE SAFE STORAGE

Separated from strong oxidants.

IPCS International Programme on Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

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DISULFIRAM ICSC: 1438

IMPORTANT DATA PHYSICAL STATE; APPEARANCE: WHITE TO GREY POWDER, WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides, sulfur oxides. Reacts violently with strong oxidants. Attacks copper. OCCUPATIONAL EXPOSURE LIMITS: TLV: 2 mg/m as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004). MAK: (Inhalable fraction) 2 mg/m; sensitization of skin (Sh); Peak limitation category: II(8); Pregnancy risk group: D; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of dust and by ingestion. INHALATION RISK: Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the endocrine system, liver, nervous system and thyroid, resulting in impaired functions. Animal tests show that this substance possibly causes toxicity to human reproduction or development. PHYSICAL PROPERTIES Boiling point at 2.3kPa: 117C Melting point: 71C Density: 1.3 g/cm Solubility in water, g/100 ml: 0.02 Octanol/water partition coefficient as log Pow: 3.9 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. NOTES In combination with alcohol the substance causes effects on cardiovascular and central nervous systems resulting in palpitation, hypotension and hyperventilation. The effects may be delayed. Do NOT take working clothes home. Antabuse and Rosulfiram are trade names. Card has been partly updated in April 2005. See section Occupational Exposure Limits. ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

1-HEPTANOL ICSC: 1082

Date of Peer Review: April 2005

Heptane-1-ol n-Heptyl alcohol 1-Hydroxyheptane n-Heptanol

CAS # 111-70-6 C7H16O / CH3(CH2)6OH RTECS # MK0350000 Molecular mass: 116.2 UN # 2810

EC #

TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING FIRE Combustible. NO open flames. Alcohol-resistant foam. Dry powder. Carbon dioxide. EXPLOSION Above 70C explosive vapour/air mixtures may be formed. Above 70C use a closed system, ventilation.

EXPOSURE

Inhalation Cough. Sore throat. Ventilation. Fresh air, rest. Skin Redness. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap. Eyes Redness. Pain. Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. Ingestion Burning sensation. Headache. Dizziness. Nausea. Drowsiness. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL PACKAGING & LABELLING Personal protection: filter respirator for organic gases and vapours. Do NOT let this chemical enter the environment. Cover the spilled material with absorbent. Collect leaking liquid in sealable containers. Do not transport with food and feedstuffs. EU Classification UN Classification UN Hazard Class: 6.1 UN Pack Group: III EMERGENCY RESPONSE STORAGE Transport Emergency Card: TEC (R)-61GT1-III Separated from strong acids, oxidants, food and feedstuffs.

IPCS International Programme on Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

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1-HEPTANOL ICSC: 1082

IMPORTANT DATA PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS: Reacts with oxidants and strong acids.

OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C; on spraying or dispersing, however, much faster.
EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the respiratory tract, and is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. At high levels the substance may cause effects on the central nervous system.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 175C Melting point: -34C Density: 0.82 g/cm Solubility in water, g/100 ml at 20C: 0.1 Vapour pressure, Pa at 20C: 15 Relative vapour density (air = 1): 4.01 Relative density of the vapour/air-mixture at 20C (air = 1): 1.01 Flash point: 70C c.c. Auto-ignition temperature: 275C Explosive limits, vol% in air: 0.9-? Octanol/water partition coefficient as log Pow: 2.62 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms.

NOTES

ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

1-HEXANOL ICSC: 1084

Date of Peer Review: October 2002

Hexyl alcohol n-Hexanol n-Hexyl alcohol 1-Hydroxyhexane Amyl carbinol Caproyl alcohol

CAS # 111-27-3 C6H14O / CH3(CH2)4CH2OH RTECS # MQ4025000 Molecular mass: 102.2 UN #

EC # 603-059-00-6

TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING FIRE Combustible. NO open flames. Alcohol-resistant foam, dry powder, carbon dioxide. EXPLOSION Above 63C explosive vapour/air mixtures may be formed. Above 63C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE

Inhalation Cough. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Skin Dry skin. Protective gloves. Rinse and then wash skin with water and soap. Eyes Redness. Pain. Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. Ingestion Burning sensation. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink.

SPILLAGE DISPOSAL PACKAGING & LABELLING Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: filter respirator for organic gases and vapours.) EU Classification Symbol: Xn R: 22 S: (2-)-24/25 UN Classification

EMERGENCY RESPONSE STORAGE NFPA Code: H1; F2; R0; Separated from strong oxidants.

IPCS International Programme on Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK

1-HEXANOL ICSC: 1084

IMPORTANT DATA PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS: Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the respiratory tract and the skin. The substance is severely irritating to the eyes. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 157C Melting point: -44.6C Relative density (water = 1): 0.82 Solubility in water, g/100 ml at 20C: 0.59 Vapour pressure, kPa at 25C: 0.124 Relative vapour density (air = 1): 3.52 Relative density of the vapour/air-mixture at 20C (air = 1): 1 Flash point: 63C c.c. Auto-ignition temperature: 290C Explosive limits, vol% in air: 1.2-7.7 calculated Octanol/water partition coefficient as log Pow: 2.03 ENVIRONMENTAL DATA

NOTES

ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

1-OCTANOL ICSC: 1030

Date of Peer Review: October 2002

n-Caprylic alcohol n-Octanol Heptyl carbinol 1-Hydroxyoctane n-Octyl alcohol

CAS # 111-87-5 C8H18O / CH3(CH2)6CH2OH RTECS # RH6550000 Molecular mass: 130.2 UN #

EC #

TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING FIRE Combustible. NO open flames. Alcohol-resistant foam, dry powder, carbon dioxide. EXPLOSION Above 81C explosive vapour/air mixtures may be formed. Above 81C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE

Inhalation Cough. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Skin Dry skin. Protective gloves. Rinse and then wash skin with water and soap. Eyes Redness. Pain. Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. Ingestion Burning sensation. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink.

SPILLAGE DISPOSAL PACKAGING & LABELLING Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: filter respirator for organic gases and vapours.) EU Classification UN Classification

EMERGENCY RESPONSE STORAGE NFPA Code: H1; F2; R0; Separated from strong oxidants.

IPCS International Programme on Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999 SEE IMPORTANT INFORMATION ON BACK

1-OCTANOL ICSC: 1030

IMPORTANT DATA PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS: Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes, the respiratory tract and is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 194-195C Melting point: -15.5C Relative density (water = 1): 0.83 Solubility in water: very poor (0.30 mg/l) at 20 C Vapour pressure, Pa at 8.7C: 20 Relative vapour density (air = 1): 4.5 Relative density of the vapour/air-mixture at 20C (air = 1): 1 Flash point: 81C c.c. Auto-ignition temperature: 253C Explosive limits, vol% in air: 0.2-30 Octanol/water partition coefficient as log Pow: 3.0 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. Do not to let this chemical enter the environment. NOTES

ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

1-DECANOL ICSC: 1490

Date of Peer Review: April 2005

Decane-1-ol n-Decyl alcohol Capric alcohol Nonyl carbinol n-Decanol

CAS # 112-30-1 C10H22O / CH3(CH2)9OH RTECS # HE4375000 Molecular mass: 158.28 UN # 3082

EC #

TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING FIRE Combustible. NO open flames. Water spray. Carbon dioxide. Alcohol-resistant foam. Dry powder. EXPLOSION

EXPOSURE

Inhalation Cough. Sore throat. Ventilation. Fresh air, rest. Skin Dry skin. Redness. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap. Eyes Redness. Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. Ingestion Abdominal pain. Burning sensationin the throat and chest. Nausea. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink.

SPILLAGE DISPOSAL PACKAGING & LABELLING Personal protection: filter respirator for organic gases and vapours. Do NOT let this chemical enter the environment. Cover the spilled material with absorbent. Collect leaking liquid in sealable containers. Marine pollutant. EU Classification UN Classification UN Hazard Class: 9 UN Pack Group: III EMERGENCY RESPONSE STORAGE Transport Emergency Card: TEC (R)-90GM6-III NFPA Code: H0; F2; R0; Separated from strong oxidants, acid anhydrides and acid chlorides. Store in an area without drain or sewer access.

IPCS International Programme on Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK

1-DECANOL ICSC: 1490

IMPORTANT DATA PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS: The substance decomposes on burning producing irritating fumes. Reacts violently with acid anhydrides, acid chlorides and strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol.

INHALATION RISK: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the skin. The substance may cause effects on the central nervous system at high levels.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 230C Melting point: 7C Density: 0.83 g/cm Solubility in water, g/100 ml at 20C: 0.37 (very poor) Vapour pressure, Pa at 20C: 1 Relative vapour density (air = 1): 5.5 Relative density of the vapour/air-mixture at 20C (air = 1): 1.01 Flash point: 108C c.c. Auto-ignition temperature: 255C Explosive limits, vol% in air: 0.7-5.5 Octanol/water partition coefficient as log Pow: 4.23 (calculated) ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. NOTES

ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

IPCS, CEC 1999

DISULFIRAM ICSC: 1438
Date of Peer Review: October 2002

Tetraethylthiuramdisulfide 1,1′-Dithiobis(N,N-diethylthioformamide) bis-(N,N-Diethylthiocarbamoyl)disulfide TETD

CAS # 97-77-8 C10H20N2S4 / ((C2H5)2NCS)2S2 RTECS # JO1225000 Molecular mass: 269.6 UN #

EC # 006-079-00-8

PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS: The substance decomposes on burning producing irritating fumes. Reacts violently with acid anhydrides, acid chlorides and strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol.

INHALATION RISK: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the skin. The substance may cause effects on the central nervous system at high levels.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 230C Melting point: 7C Density: 0.83 g/cm Solubility in water, g/100 ml at 20C: 0.37 (very poor) Vapour pressure, Pa at 20C: 1 Relative vapour density (air = 1): 5.5 Relative density of the vapour/air-mixture at 20C (air = 1): 1.01 Flash point: 108C c.c. Auto-ignition temperature: 255C Explosive limits, vol% in air: 0.7-5.5 Octanol/water partition coefficient as log Pow: 4.23 (calculated) ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. NOTES

ADDITIONAL INFORMATION

LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

IPCS, CEC 1999

DISULFIRAMICSC: 1438
Date of Peer Review: October 2002

Tetraethylthiuramdisulfide

1,1′-Dithiobis(N,N-diethylthioformamide)

bis-(N,N-Diethylthiocarbamoyl)disulfide

TETD

CAS #97-77-8C10H20N2S4 / ((C2H5)2NCS)2S2
RTECS #JO1225000Molecular mass: 269.6
UN #
EC #006-079-00-8

 

PHYSICAL STATE; APPEARANCE:

WHITE TO GREY POWDER, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:

Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.

CHEMICAL DANGERS:

The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides, sulfur oxides. Reacts violently with strong oxidants. Attacks copper.

OCCUPATIONAL EXPOSURE LIMITS:

TLV: 2 mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).

MAK: (Inhalable fraction) 2 mg/m³; sensitization of skin (Sh); Peak limitation category: II(8); Pregnancy risk group: D; (DFG 2004).

ROUTES OF EXPOSURE:

The substance can be absorbed into the body by inhalation of dust and by ingestion.

INHALATION RISK:

Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the endocrine system, liver, nervous system and thyroid, resulting in impaired functions. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

PHYSICAL PROPERTIES
Boiling point at 2.3kPa: 117°C

Melting point: 71°C

Density: 1.3 g/cm³

Solubility in water, g/100 ml: 0.02

Octanol/water partition coefficient as log Pow: 3.9
ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
In combination with alcohol the substance causes effects on cardiovascular and central nervous systems resulting in palpitation, hypotension and hyperventilation. The effects may be delayed. Do NOT take working clothes home. Antabuse and Rosulfiram are trade names.

Card has been partly updated in April 2005. See section Occupational Exposure Limits.

ADDITIONAL INFORMATION
LEGAL NOTICENeither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

 

1-HEPTANOLICSC: 1082
Date of Peer Review: April 2005

Heptane-1-ol

n-Heptyl alcohol

1-Hydroxyheptane

n-Heptanol

CAS #111-70-6C7H16O / CH3(CH2)6OH
RTECS #MK0350000Molecular mass: 116.2
UN #2810
EC #

 

PHYSICAL STATE; APPEARANCE:

COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:

Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:

TLV not established.

ROUTES OF EXPOSURE:

The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:

No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:

The substance is irritating to the respiratory tract and the skin. The substance is severely irritating to the eyes. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

The liquid defats the skin.

PHYSICAL PROPERTIES
Boiling point: 157°C

Melting point: -44.6°C

Relative density (water = 1): 0.82

Solubility in water, g/100 ml at 20°C: 0.59

Vapour pressure, kPa at 25°C: 0.124

Relative vapour density (air = 1): 3.52

Relative density of the vapour/air-mixture at 20°C (air = 1): 1

Flash point: 63°C c.c.

Auto-ignition temperature: 290°C

Explosive limits, vol% in air: 1.2-7.7 calculated

Octanol/water partition coefficient as log Pow: 2.03

ENVIRONMENTAL DATA
NOTES
ADDITIONAL INFORMATION
LEGAL NOTICENeither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

 

1-OCTANOLICSC: 1030
Date of Peer Review: October 2002

n-Caprylic alcohol

n-Octanol

Heptyl carbinol

1-Hydroxyoctane

n-Octyl alcohol

CAS #111-87-5C8H18O / CH3(CH2)6CH2OH
RTECS #RH6550000Molecular mass: 130.2
UN #
EC #

 

PHYSICAL STATE; APPEARANCE:

COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:

Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:

TLV not established.

ROUTES OF EXPOSURE:

The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:

A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:

The substance is irritating to the eyes, the respiratory tract and is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

The liquid defats the skin.

PHYSICAL PROPERTIES
Boiling point: 194-195°C

Melting point: -15.5°C

Relative density (water = 1): 0.83

Solubility in water: very poor (0.30 mg/l) at 20 °C

Vapour pressure, Pa at 8.7°C: 20

Relative vapour density (air = 1): 4.5

Relative density of the vapour/air-mixture at 20°C (air = 1): 1

Flash point: 81°C c.c.

Auto-ignition temperature: 253°C

Explosive limits, vol% in air: 0.2-30

Octanol/water partition coefficient as log Pow: 3.0

ENVIRONMENTAL DATA
The substance is harmful to aquatic organisms. Do not to let this chemical enter the environment.
NOTES
ADDITIONAL INFORMATION
LEGAL NOTICENeither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

 

1-DECANOLICSC: 1490
Date of Peer Review: April 2005

Decane-1-ol

n-Decyl alcohol

Capric alcohol

Nonyl carbinol

n-Decanol

CAS #112-30-1C10H22O / CH3(CH2)9OH
RTECS #HE4375000Molecular mass: 158.28
UN #3082
EC #

 

PHYSICAL STATE; APPEARANCE:

COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:

The substance decomposes on burning producing irritating fumes. Reacts violently with acid anhydrides, acid chlorides and strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:

TLV not established.

MAK not established.

ROUTES OF EXPOSURE:

The substance can be absorbed into the body by inhalation of its aerosol.

INHALATION RISK:

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:

The substance is irritating to the eyes and the skin. The substance may cause effects on the central nervous system at high levels.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

The liquid defats the skin.

PHYSICAL PROPERTIES
Boiling point: 230°C

Melting point: 7°C

Density: 0.83 g/cm³

Solubility in water, g/100 ml at 20°C: 0.37 (very poor)

Vapour pressure, Pa at 20°C: 1

Relative vapour density (air = 1): 5.5

Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01

Flash point: 108°C c.c.

Auto-ignition temperature: 255°C

Explosive limits, vol% in air: 0.7-5.5

Octanol/water partition coefficient as log Pow: 4.23 (calculated)

ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
ADDITIONAL INFORMATION
LEGAL NOTICENeither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
© IPCS, CEC 1999

 

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