Can CBD Help With Insomnia?

  • A study showed CBD’s potential in reducing anxiety, sleep latency in insomniacs, and promoting quality of sleep[1].
  • Researchers found that CBD indirectly increases adenosine, a chemical responsible for decreasing wakefulness and signaling the brain to sleep[2]
  • Recent clinical trials suggested that CBD might provide temporary insomnia relief. However, the results may not be sustained[3].
  • Studies have noted that both CBD and THC affect the modulation of the body’s circadian rhythm[4]
  • While studies highlight CBD’s potential in promoting and maintaining sleep, more research is required on the long-term effects of CBD in regulating the sleep cycle

Best CBD Oils for Insomnia

Editor's Pick

Spruce 750mg Lab Grade CBD Oil

Specifically formulated to be more palatable to CBD users
Spruce 750mg Lab Grade CBD Oil Bottle
  • Overall Clinical Score
    99%
    Editor's Pick
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

    Pros
    Cons
    •  Mid-strength
    •  Natural peppermint flavor
    •  Made from 100% organic and natural ingredients
    •  No other flavors
  • Features
    Discount pricing available? 20% Off Coupon Code: CBDCLINICALS
    Source
    Source of Hemp
    Kentucky, USA & North Carolina, USA
    Form Oil Tincture
    Ingredients Organic Hemp Seed Oil, Full Spectrum CBD Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    Moonshine extraction method
    How to take it Under tongue
    Potency
    Potency - CBD Per Bottle
    750 mg per bottle
    Carrier Oil Organic Hemp Seed Oil
    Concentration
    CBD Concentration Per Serving
    25mg of CBD per dropper full (1ml)
    Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana
    Flavours Peppermint
    Price Range $89 ($75.65 for subscriptions, 15% discount from regular price)
    $/mg CBD
    Price ($/mg)
    $0.12/mg ($0.10/mg with subscription)
    Shipping
    Shipping/Time to delivery
    2-4 business days (first class USPS)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants Organic, Non-GMO, no pesticides, no herbicides, no solvents or chemical fertilizers, No preservatives or sweeteners
    Allergens Vegan, Gluten free
    Refund policy Within 30 days
    Recommended for New CBD users
    Countries served USA only (all 50 states)
Check Latest Prices

Best Organic

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  • Overall Clinical Score
    99%
    Best Organic
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

    Pros
    Cons
    •  Pure CBD hemp
    •  All natural
    •  Approximately 300 drops total
    •  No other flavors
  • Features
    Discount pricing available? 20% Off Coupon Code: CBDCLINICALS20
    Source
    Source of Hemp
    Colorado, USA
    Form Oil Tincture
    Ingredients Full Spectrum Hemp Extract, Organic Virgin Hemp Seed Oil
    Type
    Type of CBD
    Full Spectrum CBD
    Extraction
    Extraction Method
    CO2 Method
    How to take it Under the tongue for approximately 30 seconds before swallowing
    Potency
    Potency - CBD Per Bottle
    900mg per bottle
    Carrier Oil Organic Hemp Oil
    Concentration
    CBD Concentration Per Serving
    60mg per dropper full (1ml)
    Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana
    Flavours Natural
    Price Range $99 - $434
    $/mg CBD
    Price ($/mg)
    $0.08 - $0.13
    Shipping
    Shipping/Time to delivery
    2-3 Days via USPS
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants No additives or preservatives, Non-GMO, NO herbicides, pesticides, or chemical fertilizers
    Allergens Not specified
    Refund policy Within 30 days
    Recommended for Health-conscious persons
    Countries served USA (all 50 states) and over 40 countries including Australia, Azerbaijan, Beliza, Bosnia & Herzegovina, Brazil, Chile, China, Croatia, Czech Republic, Estonia, France, Hong Kong, Hungary, Ireland, Israel, Japan, Latvia, Lebanon, Lithuania, Macao, Malaysia, Malta, Netherlands, New Zealand, Oman, Paraguay, Poland, Portugal, Saudi Arabia, Serbia, Singapore, South Korea, Sweden, Switzerland, United Arab Emirates, United Kingdom, Uruguay, and many more.
Check Latest Prices

Best Value

Sabaidee Super Good Vibes CBD Oil

4x the strength of a regular cbd oil
Sabaidee Super Good Vibes CBD Oil
  • Overall Clinical Score
    99%
    Best Value
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.

    Pros
    Cons
    •  Extra strong
    •  Significant benefits with just a few drops
    •  100% Natural ingredients
    •  No other flavors
  • Features
    Discount pricing available? 15% Off Coupon Code: CBDCLINICALS15
    Source
    Source of Hemp
    Colorado, USA
    Form Oil Tincture
    Ingredients Cannabidiol (CBD), Coconut Medium-chain triglycerides (MCT) Oil, Peppermint oil
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2-extraction
    How to take it Using 1-3 servings per day as needed is a good start to determine how much you need
    Potency
    Potency - CBD Per Bottle
    1000 mg per bottle
    Carrier Oil Coconut MCT Oil
    Concentration
    CBD Concentration Per Serving
    33.5 mg per dropper (1ml)
    Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana
    Flavours Peppermint
    Price Range Single Bottle - $119.95, 2-Pack - $109.97 each, 3-Pack - $98.31 each, 6-Pack - $79.99 each
    $/mg CBD
    Price ($/mg)
    Single bottle - $0.010, 2-Pack - $0.011, 3-Pack - $0.009, 6-Pack - $0.007
    Shipping
    Shipping/Time to delivery
    3-5 Business days
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants Contaminant-free
    Allergens Vegan and Gluten-free
    Refund policy Within 30 days
    Recommended for Patients who are looking for serious CBD oil support
    Countries served USA only (all 50 states)
Check Latest Prices

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg

Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
cbdMD CBD Oil Tincture Natural 1500mg
  • Overall Clinical Score
    99%
    Best Natural Alternative
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

    Pros
    Cons
    •  Various delicious flavors to choose from
    •  Has vegan, organic, and gluten-free ingredients
    •  Free shipping for this particular product within USA
    •  World-class customer service team
    •  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
  • Features
    Discount pricing available? 15% Off Coupon Code: cbdMD15
    Source
    Source of Hemp
    Kentucky, USA
    Form Oil Tincture
    Ingredients Cannabidiol (CBD), MCT Oil, and Flavoring
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2 extraction method
    How to take it Under tongue
    Potency
    Potency - CBD Per Bottle
    1500mg per bottle
    Carrier Oil Organic Coconut MCT Oil
    Concentration
    CBD Concentration Per Serving
    50mg per dropper full (1ml)
    Drug Test Containing less than 0.3% THC, there are still trace amounts
    Flavours Natural, Berry, Orange and Mint
    Price Range $99.99
    $/mg CBD
    Price ($/mg)
    $0.07
    Shipping
    Shipping/Time to delivery
    2-5 Business days (via Fedex)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants 100% organic, non-GMO, and vegan-certified
    Allergens Vegan, Gluten free
    Refund policy Within 30 days
    Recommended for Daily CBD oil users
    Countries served USA only (all 50 states)
Check Latest Prices

Why People Are Turning to CBD for Insomnia

About 4% of people regularly use sleeping agents to alleviate sleep disruptions, like insomnia[5]. However, some of these treatments may have adverse effects, and others may take time before producing the desired outcome.

The prevalence of insomnia in the general population ranges between 8-40%. While up to 30% of the population reports experiencing some symptoms of insomnia, another 8-10% suffers from chronic insomnia[6].

Among the more natural supplements to conventional insomnia treatments, a possible alternative that has emerged at the forefront is CBD (cannabidiol).

Numerous studies have shown how CBD might potentially help with sleep problems, such as insomnia and its symptoms. 

A study was conducted on the effects of CBD on the sleep-wake cycle of rats[7]

It was found that CBD oil increased the duration of the “deep sleep” phase while reducing rapid eye movement or REM sleep. Rapid eye movement is the phase of sleep in which dreaming occurs. 

A 2014 research on patients with Parkinson’s disease also showed how CBD might affect the sleep cycle[8].

The research concluded that CBD improved the symptoms of RBD (REM sleep behavior disorder). RBD is associated with nightmares and poor sleep. 

In a 2016 case study, researchers administered 25mg CBD plus a 3mg spray to a 10-year girl with post-traumatic stress disorder (PTSD). It was reported that CBD helped reduce insomnia and sleep disturbances in the subject[9]

In another research, scientists noted that when given a higher dose of CBD per day, a significant increase in the subjects’ sleep quality can be observed, along with a decrease in dream recollection. 

Reports of increased total sleep time and less sleep fragmentation were also documented in the research. No adverse effects were observed on the following day[10].

These findings support the hypothesis that low-dose CBD may have stimulating effects while higher doses may act as sedatives[11].    

According to a review in Frontiers in Pharmacology, there is a fair amount of evidence to support the claim that CBD soothes pain[12]. The authors noted that by reducing chronic pain, CBD also improves sleep. 

Chronic insomnia is often closely linked to anxiety. People who have trouble staying asleep, or experience sleeplessness, are often anxious about aspects of their waking life or their poor sleep patterns[13]

A 2019 case series in The Permanente Journal looked into CBD’s effects on sleep and anxiety[14]. The subjects were given 25mg of CBD in capsule form each day.

After the first month, 66.7% of the patients reported better sleep and 79.2% reported lower anxiety levels.

Evidence also pointed out that CBD has a calming effect in the central nervous system and helps aid neuropsychiatric disorders[15]

It means that CBD acts as a natural sleep aid without the side effects of over-the-counter drugs or prescribed sleep medications. 

However, these results fluctuated over time, prompting researchers to conclude that people might achieve short-term results with CBD intake. The effects may not be sustained[16].

The current studies available for CBD and sleep are promising, but more research needs to be conducted to determine its long-term effects.

How CBD Oil Works to Help with Insomnia

Understanding how CBD may help with insomnia requires understanding how the endocannabinoid system (ECS) functions.

The ECS is responsible for keeping the body’s state of homeostasis, allowing proper enzyme action and cell function. 

To keep the body in a homeostatic or balanced state, the ECS regulates pain sensation, metabolism, and memory. It also plays a role in regulating mood, sleep, and appetite.

The ECS functions via its two central receptors, CB1 and CB2. These receptors connect with chemical messengers or endocannabinoids in the body, and signal the ECS to perform its functions. 

Each receptor can be found in specific parts of the human body and plays a particular role in the ECS.

The CB1 and CB2 receptors also bind with compounds from outside the body, called phytocannabinoids. 

Phytocannabinoids are abundant in the plant Cannabis sativa, and two of the most well-studied are CBD and THC.

CBD (cannabidiol) is a natural compound derived from the cannabis plant. It has been linked to multiple health benefits, such as relief from pain and anxiety[17]

Unlike marijuana, most CBD oils contain only trace amounts of THC (less than 0.3%). THC (tetrahydrocannabinol) is another well-known cannabinoid that produces psychoactive effects.

Endocannabinoids through the CB1 receptor regulate the stability of non-REM sleep[18]

Studies on both CBD and THC observed that both cannabinoids affect the ECS components involved in the modulation of the body’s circadian rhythm, including the promotion and maintenance of sleep.

Researchers attributed this modulation on both cannabinoids‘ relationship with CB1 and CB2 receptors[19]

For example, THC binds with and partially affects CB1 receptors. Meanwhile, CBD binds with and indirectly affects CB1 and CB2 receptors.

CBD’s binding to CB1 receptors has been noted to increase the concentration of anandamide in the body by moderately inhibiting its degradation[20]

Anandamide, also known as the “bliss molecule,” is a naturally-occurring cannabinoid in the body that helps regulate the “reward” circuitry of the brain.

In a 2003 study, scientists observed that anandamide’s presence gradually increases the brain’s adenosine level[21]. Adenosine is a chemical that decreases wakefulness and signals the brain to sleep. 

The results of the study suggested that CBD might help reduce sleep latency on insomniacs[22]. Sleep latency is the amount of time it takes to go from being fully awake to sleeping. 

The Pros and Cons of CBD for Insomnia

The Pros

  • A study on rats found that CBD increased the duration of the “deep sleep” phase while reducing REM sleep[23].
  • In a 2014 research, it was found that CBD improved RBD (REM sleep behavior disorder) symptoms[24].
  • Patients who took CBD reported better sleep and lower anxiety levels[25]
  • Evidence pointed out that CBD acts as a natural sleep aid without the side effects of prescribed sleep medications[26]
  • CBD shows promise in reducing sleep latency in insomniacs while promoting quality of sleep[27].
  • CBD has been shown to produce little to no side effects that can affect subjects’ daytime activities[28].
  • According to the World Health Organization (WHO), CBD “is generally well-tolerated with a good safety profile[29].”
  • The National Institute on Drug Abuse (NIDA) classified CBD as “non-addictive[30].”

The Cons

  • Evidence suggests CBD’s limitation as an insomnia treatment in the long-term.
  • Studies on CBD’s efficacy as a treatment for conditions, such as insomnia, are still limited.
  • The US Food and Drug Administration (FDA) has yet to approve the use of CBD on insomnia.
  • Side effects of CBD may include diarrhea, dry mouth, reduced appetite, fatigue, and drowsiness[31].
  • CBD may adversely interact with patients’ medications[32].

How CBD Oil Compares to Alternative Treatments for Insomnia

People commonly use sleeping pills and other prescribed medications for their sleep issues. However, these treatments offer a short-term solution and often come with unpleasant side effects[33].

There are alternative and holistic treatments an individual may try to help with insomnia. 

Some studies have suggested that herbal supplements, like valerian root, may help with the onset of sleep and sleep maintenance[34]

Chamomile is another commonly used alternative for insomnia. The FDA has considered this herb as safe without known adverse effects[35]

Essential oils used in aromatherapy are also found to be beneficial in promoting and sustaining sleep. A study reported that a mixture of essential oils, like lavender,  reduced sleep disturbances and increased well-being in older adults[36].

Melatonin is a hormone that plays a vital role in regulating the sleep-wake cycle and other circadian rhythms[37]. It may be used as a supplement to help an individual fall asleep more quickly.

According to a study, melatonin may also be a possible treatment for circadian rhythm disorders. It may also help decrease sleep disturbances caused by jet lag[38]

Acupuncture is another treatment for insomnia that is often used in traditional Chinese medicine[39]. This procedure involves the insertion of fine needles through the skin to target strategic points in the body.

Although commonly used for pain relief, acupuncture may help improve the sleep quality of people with insomnia, as preliminary clinical trials have indicated[40].

CBD oil has also shown the potential to relieve symptoms of insomnia[41]. Some CBD teas or topicals contain chamomile, lavender, and valerian root to produce calming and relaxing effects.

Several CBD gummies and capsules are also infused with melatonin to promote restful sleep. 

How to Choose the Right CBD for Insomnia 

There are three types of CBD oil to choose from: full-spectrum, broad-spectrum, and CBD isolates.

Full-spectrum CBD oil contains different plant-based compounds, including phytocannabinoids, terpenes, and other phytonutrients. These compounds work together to create an “entourage effect.”

Broad-spectrum CBD contains multiple cannabinoids found in the hemp plant but does not contain THC

CBD isolates contain pure CBD with no other cannabinoids

In choosing the best CBD oil for sleep, there are different factors to consider.

Source of Hemp – The hemp extract may come from Colorado or some parts of Europe, for instance. One should look for CBD products derived from non-GMO, organic hemp to ensure that it is free from pesticides or harmful contaminants. 

Extraction Method – The extraction process involves the separation of the CBD extract from the hemp plant. It may be through CO2 extraction or ethanol extraction. 

Carrier Oil – Carrier oils help increase the bioavailability or absorption rate of CBD in the body. The most common carrier oils used in CBD products are hempseed oil, coconut oil or MCT oil, and olive oil

Lab Testing – Reliable CBD companies get their products tested by a third-party lab to ensure the highest quality, potency, and safety of their products. They must also post the lab results of their CBD products on their website. 

Taste – CBD hemp oil may be unflavored or come in various flavors, such as peppermint or chocolate, to help mask the strong taste of hemp.

Company Policies – Some CBD brands, such as NuLeaf Naturals, Charlotte’s Web, and Fab CBD, provide some of the best CBD oils for sleep. Check if they offer a money-back guarantee and research on their policies on shipping, returns, and refund. 

Legality – The use of medical marijuana is illegal on the federal level but is legal under some state laws. 

Hemp-derived CBD products with less than 0.3 percent THC are legal under federal laws but are still illegal under some state laws.

In the United States, the use of cannabis is allowed for specific medical conditions, such as epilepsy. 

Epidiolex is the first and only CBD treatment for seizures approved by the FDA[42]

There are different places where one can buy CBD products:

Dispensaries – It is advisable to purchase CBD in local dispensaries cannabis shops. The employees are more likely to be knowledgeable about the CBD products, its ingredients, and benefits.

Health Shops – Nowadays, many health shops or retail pharmacies also sell CBD products. However, keep in mind that products found in dispensaries are more likely to be tested by third-party labs than those sold in other stores. 

Official Online Stores – When buying CBD products online, it is recommended to purchase directly from the brand’s official website. One should also research about the brand’s reliability and its products.

CBD Dosage for Insomnia 

CBD dosage varies from person to person. It depends on different factors, including age, height, weight, and genetics.

A study has found that 25mg to 75mg of CBD per day produced significant effects on human adults with insomnia and anxiety[43].

First-time CBD users are advised to start with low daily doses of CBD between 1 milligram CBD per kilogram of body weight to 50 milligrams CBD per kilogram of body weight (< 1 mg/kg to 50 mg/kg per day)[44]

Once the body gets used to the CBD in their system, the dosage can be gradually increased.

Before taking CBD, it is recommended to consult a medical professional to find a suitable starting dosage. 

How to Take CBD for Insomnia

CBD oils may be taken as tinctures, capsules, gummies, topicals, or vapes

CBD tinctures are taken sublingually by using a dropper to place the oil under the tongue. The oil tincture can also be added to food and drinks, but it may affect CBD absorption.

CBD capsules are recommended for those who want to know exactly how much they are taking. These supplements are sometimes formulated with ingredients like melatonin, to act as a natural sleep aid.

CBD may also be consumed through edibles, such as CBD gummies or mints. In these forms, CBD’s effects may take a while to kick in, so it is best to take one around 30 minutes before bedtime[45]

Some CBD gummies are also infused with melatonin to support a good night’s sleep. However, be wary of products containing added sugar, which may make it difficult to fall asleep. 

Topicals include CBD-infused lotions, creams, balms, and salves, which are applied directly to the skin. These CBD products are often mixed with essential oils to promote calm, relaxation, and better sleep. 

Lastly, vaping provides faster effects and better absorption of CBD into the body, among other methods[46]. However, it is found that vape use may cause several lung diseases and injuries[47]

What is Insomnia?

Insomnia is the most common among all sleep disorders. According to the American Psychiatric Association (APA), about one-third of all adults report symptoms of insomnia[48].

It is associated with difficulty falling asleep, frequent night-time awakenings with difficulty returning to sleep, and awakening earlier than desired.

This sleep disorder is also characterized by dissatisfaction with sleep quantity or quality, often leading to significant distress or impairment in functioning. 

Insomnia symptoms can manifest in the daytime. These symptoms include fatigue, mood disturbances, daytime sleepiness, and cognitive impairment.  

On its own, insomnia may be a result of stress, abrupt changes in work schedule, jetlag, and poor sleeping and eating habits. Consuming stimulants, as well as certain medications, may also cause insomnia.

Medical conditions, such as sleep apnea, arthritis, restless leg syndrome (RLS), allergies, or congestive heart failure, may also lead to insomnia. In postpartum and premenopausal women, hormonal shifts are highlighted as causes of insomnia[49].

According to the National Alliance on Mental Illness (NAMI), about 50% of insomnia cases are related to mental conditions, such as psychological stress, anxiety, and depression[50].

Insomnia has been found to increase an individual’s risk for multiple conditions[51]. These conditions include a weak immune system, stroke, high blood pressure, asthma attacks, and heart disease.

The Importance of Sleep

Sleep is necessary for optimal health, as it directly affects an individual’s physical, mental, and emotional balance. 

Recent studies have shown robust and objective proof that sleep serves an essential function in weight, mood, and hormone levels[52]

In contrast, sleep deprivation may result in irritability, difficulty concentrating, and lapses in memory[53]. It may also affect different areas in the body, such as the heart, muscles, and digestive organs. 

Getting the right amount of sleep every night has been observed to produce short-term and long-term health consequences.

According to the American Academy of Sleep Medicine (AASM) and Sleep Research Society (SRS), the recommended amount of sleep for adults is seven to nine hours per night[54]

A 2010 review also reported that sufficient sleep duration at night decreases the risk of early death[55]

The National Sleep Foundation advises on developing good sleep hygiene, which includes one’s bedroom setting and sleep-related habits[56]

Here are some ways an individual can sleep better:

  • Stick to a consistent sleep schedule every day, even on weekends. 
  • Practice a relaxing pre-bedtime routine to prepare the mind and body for sleep.
  • Disconnect from electronic devices, like mobile phones and laptops, and keep them out of bed.
  • Carefully monitor the intake of stimulants, such as caffeine and alcohol. Avoid consuming them hours before going to sleep. 
  • Minimize potential light and sound disruptions while optimizing bedroom temperature and environment.  
  • Choose a comfortable and supportive mattress with quality pillows and bedding.

Conclusion

Insomnia is a common sleep disorder characterized by difficulty falling asleep, frequent night-time awakenings with difficulty returning to sleep, and early morning wakefulness. 

Its symptoms can also affect daytime activities, causing fatigue, mood disturbances, daytime sleepiness, and cognitive impairment.

People regularly use sleeping pills and prescription medications to alleviate symptoms of insomnia. However, some of these treatments may have adverse side effects and may take time to work.

CBD is generally a safe alternative to insomnia treatments. Multiple studies have highlighted CBD’s effects on the body’s sleep-wake cycle. 

CBD showed potential in reducing sleep latency and improving the sleep quality of people with sleep disorders, such as insomnia, and RBD (REM sleep behavior disorder). 

In these clinical trials, patients who took CBD reported lower anxiety levels and better sleep. However, the results may not be sustained. 

Studies have noted that both CBD and THC affect the modulation of the body’s circadian rhythm. 

Researchers also found that CBD indirectly increases adenosine to decrease wakefulness and signal the brain to sleep.

Although there is plenty of supporting evidence that suggests how CBD may improve sleep and relieve insomnia symptoms, the results are not conclusive. More research is still required to determine the long-term effects of CBD in regulating the sleep cycle

CBD products come in different forms to help with insomnia. CBD capsules, gummies, and topicals are often infused with melatonin and essential oils to promote calm and better sleep. 

Before buying CBD, it is recommended to seek medical advice on proper usage and dosage. 


  1. Gates, P. J., Albertella, L., & Copeland, J. (2014). The effects of cannabinoid administration on sleep: a systematic review of human studies. Sleep medicine reviews, 18(6), 477-487.
  2. Murillo-Rodriguez, E., Blanco-Centurion, C., Sanchez, C., Daniele, P., & Shiromani, P. J. (2003). Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. Sleep, 26(8), 943-947.
  3. Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in anxiety and sleep: a large case series. The Permanente Journal, 23.
  4. Suraev, Anastasia, Ronald R Grunstein, Nathaniel S Marshall, Angela L D’rozario, Christopher J Gordon, Delwyn J Bartlett, Keith Wong, et al. “Cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (THC) for Chronic Insomnia Disorder (‘CANSLEEP’ Trial): Protocol for a Randomised, Placebo-Controlled, Double-Blinded, Proof-of-Concept Trial.” BMJ Open 10, no. 5 (2020). https://doi.org/10.1136/bmjopen-2019-034421.
  5. Fernandez-Mendoza, Julio, and Alexandros N. Vgontzas. “Insomnia and Its Impact on Physical and Mental Health.” Current Psychiatry Reports 15, no. 12 (2013). https://doi.org/10.1007/s11920-013-0418-8.
  6. Ibid. 
  7. Chagas, M. H. N., Crippa, J. A. S., Zuardi, A. W., Hallak, J. E., Machado-de-Sousa, J. P., Hirotsu, C., … & Andersen, M. L. (2013). Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats. Journal of Psychopharmacology, 27(3), 312-316.
  8. Chagas, M. H., Eckeli, A. L., Zuardi, A. W., Pena‐Pereira, M. A., Sobreira‐Neto, M. A., Sobreira, E. T., … & Tumas, V. (2014). Cannabidiol can improve complex sleep‐related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients: a case series. Journal of clinical pharmacy and therapeutics, 39(5), 564-566.
  9. Shannon, S., & Opila-Lehman, J. (2016). Effectiveness of cannabidiol oil for pediatric anxiety and insomnia as part of posttraumatic stress disorder: a case report. The Permanente Journal, 20(4).
  10. Carlini, Elisaldo A., and Jomar M. Cunha. “Hypnotic and Antiepileptic Effects of Cannabidiol.” The Journal of Clinical Pharmacology 21, no. S1 (1981). https://doi.org/10.1002/j.1552-4604.1981.tb02622.x.
  11. Babson, Kimberly A., James Sottile, and Danielle Morabito. “Cannabis, Cannabinoids, and Sleep: a Review of the Literature.” Current Psychiatry Reports 19, no. 4 (2017). https://doi.org/10.1007/s11920-017-0775-9.
  12. Vučković, S., Srebro, D., Vujović, K. S., Vučetić, Č., & Prostran, M. (2018). Cannabinoids and pain: new insights from old molecules. Frontiers in pharmacology, 9, 1259.
  13. Molen, Y. F., Carvalho, L. B. C., Prado, L. B. F. D., & Prado, G. F. D. (2014). Insomnia: psychological and neurobiological aspects and non-pharmacological treatments. Arquivos de neuro-psiquiatria, 72(1), 63-71.
  14. Ibid.
  15. Ibid.
  16. Ibid.
  17. De Gregorio, D., McLaughlin, R. J., Posa, L., Ochoa-Sanchez, R., Enns, J., Lopez-Canul, M., … & Gobbi, G. (2019). Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain, 160(1), 136.
  18. Pava, M. J., Makriyannis, A., & Lovinger, D. M. (2016). Endocannabinoid signaling regulates sleep stability. PloS one, 11(3), e0152473.
  19. Ibid.
  20. Ibid.
  21. Ibid.
  22. Ibid.
  23. Ibid.
  24. Ibid.
  25. Ibid.
  26. Ibid.
  27. Ibid.
  28. Carlini, E. A. (1981). Cunha. JA, Hypnotic and anti-epileptic effects of CBD. Journal of Clinical Pharmacology, 21, 4178-4278.
  29. World Health Organization (WHO). (2018). Cannabidiol (CBD) Critical Review Report. https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  30. NIDA. Researching Marijuana for Therapeutic Purposes: The Potential Promise of Cannabidiol (CBD). National Institute on Drug Abuse website. https://www.drugabuse.gov/about-nida/noras-blog/2015/07/researching-marijuana-therapeutic-purposes-potential-promise-cannabidiol-cbd. July 20, 2015. Accessed July 21, 2020.
  31. Machado Bergamaschi, M., Helena Costa Queiroz, R., Waldo Zuardi, A., & Crippa, A. S. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current drug safety, 6(4), 237-249.
  32. Brown, J. D., & Winterstein, A. G. (2019). Potential adverse drug events and drug–drug interactions with medical and consumer cannabidiol (CBD) use. Journal of clinical medicine, 8(7), 989.
  33. Lemmer, B. (2007). The sleep–wake cycle and sleeping pills. Physiology & behavior, 90(2-3), 285-293.
  34. Bent, S., Padula, A., Moore, D., Patterson, M., & Mehling, W. (2006). Valerian for sleep: a systematic review and meta-analysis. The American journal of medicine, 119(12), 1005-1012.
  35. Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: a herbal medicine of the past with a bright future. Molecular medicine reports, 3(6), 895-901.
  36. Chien, L. W., Cheng, S. L., & Liu, C. F. (2012). The effect of lavender aromatherapy on autonomic nervous system in midlife women with insomnia. Evidence-based complementary and alternative medicine, 2012.
  37. Cagnacci, A., Elliott, J. A., & Yen, S. S. (1992). Melatonin: a major regulator of the circadian rhythm of core temperature in humans. The Journal of Clinical Endocrinology & Metabolism, 75(2), 447-452.
  38. Arendt, J., Skene, D. J., Middleton, B., Lockley, S. W., & Deacon, S. (1997). Efficacy of melatonin treatment in jet lag, shift work, and blindness. Journal of biological rhythms, 12(6), 604-617.
  39. Sok, S. R., Erlen, J. A., & Kim, K. B. (2003). Effects of acupuncture therapy on insomnia. Journal of Advanced Nursing, 44(4), 375-384.
  40. Cao, H., Pan, X., Li, H., & Liu, J. (2009). Acupuncture for treatment of insomnia: a systematic review of randomized controlled trials. The journal of alternative and complementary medicine, 15(11), 1171-1186.
  41. Ibid.
  42. Rubin, R. (2018). The path to the first FDA-approved cannabis-derived treatment and what comes next. Jama, 320(12), 1227-1229.
  43. Ibid.
  44. Millar, S. A., Stone, N. L., Bellman, Z. D., Yates, A. S., England, T. J., & O’Sullivan, S. E. (2019). A systematic review of cannabidiol dosing in clinical populations. British journal of clinical pharmacology, 85(9), 1888–1900. https://doi.org/10.1111/bcp.14038
  45. Paudel, K. S., Hammell, D. C., Agu, R. U., Valiveti, S., & Stinchcomb, A. L. (2010). Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. Drug development and industrial pharmacy, 36(9), 1088-1097. https://doi.org/10.3109/03639041003657295 
  46. Ibid.
  47.  Broderick, S. (2020). What Does Vaping Do to Your Lungs? Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/wellness-and-prevention/what-does-vaping-do-to-your-lungs
  48. Buysse, D. J. (2008). Chronic insomnia. American journal of psychiatry, 165(6), 678-686.
  49. Ibid. 
  50. NAMI. “Sleep Disorders.”  Accessed July 21, 2020. https://www.nami.org/About-Mental-Illness/Common-with-Mental-Illness/Sleep-Disorders.
  51. Taylor, D. J., Lichstein, K. L., & Durrence, H. H. (2003). Insomnia as a health risk factor. Behavioral sleep medicine, 1(4), 227-247.
  52. Cirelli, Chiara, and Giulio Tononi. “Is Sleep Essential?” PLoS Biology 6, no. 8 (2008). https://doi.org/10.1371/journal.pbio.0060216.
  53. Hughes, R. G., & Rogers, A. E. (2004). Are You Tired?: Sleep deprivation compromises nurses’ health—and jeopardizes patients. AJN The American Journal of Nursing, 104(3), 36-38.
  54. Consensus Conference Panel, Watson, N. F., Badr, M. S., Belenky, G., Bliwise, D. L., Buxton, O. M., … & Kushida, C. (2015). Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. Journal of Clinical Sleep Medicine, 11(6), 591-592.
  55. Cappuccio, F. P., D’Elia, L., Strazzullo, P., & Miller, M. A. (2010). Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep, 33(5), 585-592.
  56. Suni, E. (2020). How Much Sleep Do We Really Need? National Sleep Foundation.org. https://www.sleepfoundation.org/articles/how-much-sleep-do-we-really-need
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