- Medical research suggested that tinnitus is a form of sensory epilepsy(1). Researchers mentioned that cannabinoid drugs, like products with CBD, may provide tinnitus relief(2).
- CBD or cannabidiol has purported antiepileptic properties(3). This therapeutic potential may help address one of the leading tinnitus causes, which is hyperactivity in the brain’s auditory areas.
- However, an animal study published in Frontiers in Neurology showed that CBD administration aggravated tinnitus in rat subjects and predisposed those with pre-existing ear damage to developing a hearing problem(4).
- Anxiety and stress also play a crucial role in tinnitus. Stress is known to worsen the symptom. Additionally, tinnitus patients often feel anxious and emotionally distressed due to their hearing problems(5).
CBD has putative antianxiety properties(6). This medical potential may help relieve the anxiety and stress tinnitus patients experience. However, more longitudinal, clinical research is necessary to determine how CBD may help with tinnitus.
Best CBD for Tinnitus
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This Spruce CBD gummies offers you a real relief from your exhausting day to day routine It comes in three different flavors that includes Mixed Berry, Orange and Strawberry. It is made from 100% all natural ingredients.
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The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.
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Why People Are Using CBD Oil for Tinnitus
Medical research has hypothesized tinnitus to be a form of epilepsy, a neurological disorder of the electrical impulses that travel in neurons(7).
Some individuals use CBD products like CBD oil to help with epilepsy due to cannabidiol’s antiepileptic potential(8).
Many CBD users have also claimed that CBD oil helped relieve symptoms of hearing disorders, such as tinnitus and hyperacusis (increased sensitivity to sound).
Despite public opinion being positive, most information supporting CBD oil as an effective treatment for tinnitus symptoms comes from anecdotal evidence.
Mayo Clinic defines tinnitus as a feeling of ringing or noise in the ears when nothing within the environment is causing these sounds to occur(9).
Tinnitus symptoms include hearing phantom sounds, such as ringing, buzzing, clicking, hissing, roaring, and even humming.
The noise varies in pitch from low to high. However, some tinnitus sufferers have severe cases, as they cannot concentrate or hear other sounds fully.
According to The American Academy of Audiology, around 30 million people in America have tinnitus(10).
Still, it is worth noting that tinnitus is not considered a disorder but a symptom that has some underlying causes. The causes of tinnitus include:
- Hearing loss (due to old age)
- Ear infection
- Ear injury
- Excessive earwax
- Constant exposure to loud noises
- Neck injuries
- Medical conditions, like circulatory system disorders, blood vessel disorders, or Meniere’s Disease (a disorder affecting the inner ear, caused by “triggers” such as stress, post-traumatic stress disorder (PTSD), and emotional distress(11)
Most people experience subjective tinnitus, in which they only hear phantom sounds(12).
On the other hand, cases of objective tinnitus allow patients to hear existing sounds, such as heart murmurs (a sound accompanying abnormal heartbeats)(13).
Tinnitus usually occurs when hair cells in the cochlea are damaged(14).
The cochlea is a spiral-shaped bone that plays an essential role in the body’s auditory process.
In the cochlea, the sounds humans hear become electric impulses or nerve signals, which the brain interprets as sound frequencies(15).
When the hair cells in the cochlea are damaged, the brain makes an increased effort to detect the nerve signals it cannot receive by increasing neuronal activity.
This action is equivalent to using more antennas to get a better signal for one’s radio.
Such a response is the brain’s way of compensating for hearing loss.
This hyperactivity in the auditory part of the brain leads to an excess of electrical noises that take the form of tinnitus.
Although most cases of tinnitus are caused by hearing loss at the cochlea, studies suggested that there may be a connection between epilepsy and tinnitus(16).
Research also suggested that tinnitus may be a form of sensory epilepsy(17). Tinnitus typically occurs when there is hyperactivity in the auditory areas of the brain.
Since tinnitus links to neural brain activity, researchers investigated whether the use of cannabinoids, like CBD, might be effective in lessening the symptoms of tinnitus.
Cannabinoids have exhibited therapeutic actions that could suppress epileptic and seizure activity in animals(18). CBD is one of the major cannabinoids.
Studies showed that CBD has well-known antiepileptic and anti-anxiety properties(19). These properties may prove to be an effective treatment for bringing tinnitus relief.
Epidiolex was the first approved antiepileptic drug to contain CBD in its active ingredients(20).
However, research examining the effects of CBD on tinnitus treatment is limited. Additionally, scientists have not conducted studies utilizing human subjects.
One significant research investigated whether cannabinoids, like CBD, may affect tinnitus(21).
The researchers administered a 1:1 ratio of cannabidiol (CBD) and tetrahydrocannabinol (THC) to lab rats with acoustic trauma-induced tinnitus.
THC is a cannabis-derived compound known to produce psychoactive effects, creating a feeling of “high” among marijuana users(22).
However, findings revealed that the administration of CBD and THC exacerbated tinnitus in rat models. These cannabinoids even caused tinnitus in the group of subjects that did not initially have a hearing problem.
The findings led researchers to believe that cannabinoids like CBD and/or THC may increase the development of tinnitus in subjects with pre-existing hearing damage.
However, other individuals assume that while CBD may not be an effective tinnitus treatment, the non-psychoactive compound may help alleviate the stress and anxiety that tinnitus patients experience due to their hearing problems.
CBD has purported antidepressant and antianxiety properties(23). These therapeutic potentials may help inhibit anxiety and depression, common among tinnitus sufferers(24). However, evidence to support this hypothesis is still developing.
While current research suggests that cannabinoid use may aggravate tinnitus, further studies are still needed to validate such findings.
Still, many individuals believe that CBD’s neuroprotective properties may help provide tinnitus sufferers a much needed anxiety relief due to emotional distress that accompanies the hearing problem.
Tinnitus patients should consult an audiologist, primary care doctor, ENT specialist, or other medical professional before administering or adding CBD oil to their current treatment.
How CBD Oil May Work for Tinnitus
Learning how the endocannabinoid system (ECS) interacts with CBD is key to understanding how CBD may work to relieve tinnitus.
The ECS is an essential biological system that regulates various bodily processes, such as sleep, memory, temperature control, immune response, pain control, and inflammatory reactions(25).
The ECS comprises endocannabinoids, cannabinoid receptors, and enzymes.
Endocannabinoids are cannabinoids created in the body naturally, while phytocannabinoids, like CBD, are plant-based cannabinoids present in the cannabis plant.
These cannabinoids act as signals for the body to take action. When they bind to cannabinoid receptors, a specific action may be triggered.
The two primary types of cannabinoid receptors are CB1 and CB2 receptors. While CB1 receptors are abundant in the brain and spinal cord, CB2 receptors are primarily present in immune cells and other organs.
CBD’s antiepileptic and antianxiety properties activate upon its binding with CB1 and CB2 receptors.
A study suggests that various forms of cannabinoids may prove beneficial for patients who have tinnitus(26).
The researchers attribute cannabinoid interactions with CB1 and CB2 receptors as a potential target for treating tinnitus.
Researchers claim that cannabinoids like CBD may decrease overactive neurons in the brain, giving rise to its antiepileptic and anxiety-inhibiting effects.
However, findings from other studies suggest that cannabinoids may do the opposite for auditory brain regions, which may explain why it aggravated tinnitus in one animal research(27).
Scientists must conduct further studies to fully illustrate how CBD or THC and its interactions with cannabinoid receptors may affect tinnitus in patients.
CBD is one of the hundred phytocannabinoids in the Cannabis sativa plant.
CBD oil, a popular CBD product, is produced from industrial hemp plants, one of the variants of the cannabis plant.
Unlike the marijuana plant, industrial hemp contains less than 0.3% THC. As a result, CBD and hemp products extracted from industrial hemp are nonpsychoactive and do not make their users high.
The Pros and Cons of CBD for Tinnitus
Pros
- The World Health Organization (WHO) states that CBD is generally well tolerated by its users and has a good safety profile(28).
- Federal law regulating CBD oil has become lax due to the recent legalization of the 2018 Farm Bill. Because of this, the cultivation and selling of CBD products have been authorized by the United States Food and Drug Administration (US FDA)(29). Still, CBD legality varies according to state law.
- Various CBD products in different formats now exist on the market, including CBD tinctures, oil drops, sprays, capsules, gummies, and vape. Individuals living with tinnitus may choose which CBD product best suits their lifestyle and needs.
- Unlike THC, CBD does not make its users high. As a result, individuals may experience the health benefits of CBD without this significant disadvantage.
- CBD has potential antianxiety and antidepressant benefits(30). These properties may help tinnitus patients relieve the stress and anxiety they feel due to their hearing problems.
Cons
- Tinnitus symptoms may become worse with cannabinoid use(31).
- One study found that CBD and THC worsened tinnitus in rat subjects. The study also found that subjects with pre-existing hearing damage were more prone to tinnitus after administering both cannabinoids.
- CBD may interact negatively with other drugs taken alongside it(32). Tinnitus patients who plan to use CBD for relief must consult a medical professional before initial administration.
- Individuals taking CBD oil may experience potential side effects, such as dry mouth, fatigue, drowsiness, diarrhea, and reduced appetite(33).
- Data on CBD’s ability to relieve tinnitus is still inconclusive. Further studies are needed to validate existing research findings.
How CBD Oil Compares to Alternative Treatment Options for Tinnitus
The recent hype around CBD oil as a possible tinnitus treatment may be explained by the lack of a proper cure for tinnitus.
The FDA has not approved any effective drug treatment for tinnitus. Clinical trials have not shown existing drugs, herbs, or supplements to be more effective than a placebo.
However, effective methods to manage tinnitus exist, such as hearing aids and behavioral strategies(34). These strategies include:
- Cognitive behavioral therapy (CBT): Uses relaxation and cognitive restructuring to change how individuals think about and respond to tinnitus.
- Tinnitus retraining therapy (TRT): Aims to habituate or accustom the individual’s auditory system to tinnitus signals and make these indicators less noticeable or bothersome.
Medical professionals and audiologists recommend the combined use of sound-generating devices and behavioral strategies, such as CBT, TRT, and stress management.
These behavioral strategies all function to put individuals living with tinnitus in a relaxed state, as stress may worsen the symptom in patients.
In particular, the behavioral strategies commonly used to manage tinnitus let patients restructure their thoughts and change how they respond to the symptom.
In the case of tinnitus retraining therapy, patients’ minds are rehabilitated to the point where they no longer notice or are bothered by the phantom sounds.
CBD’s anxiety-inhibiting properties may serve a similar function.
However, it is essential to remember that CBD oil is not a cure for tinnitus or its underlying causes.
Individuals with tinnitus should seek the advice of an audiologist or medical professional before using CBD oil as an alternative treatment for tinnitus relief.
How to Choose the Best CBD Oil for Tinnitus
Keep in mind the following factors when choosing high quality CBD products for tinnitus:
- Full-spectrum CBD oil contains most of the active cannabinoids, minerals, compounds, flavonoids, terpenes, and fatty acids in the hemp plant.
Flavonoids are plant-based compounds that function as antimicrobials and antioxidants(35). Meanwhile, terpenes are essential oil constituents that give the cannabis plant its distinct aroma(36).
Full-spectrum CBD oil is often recommended for individuals who want to try CBD oil for the first time.
In full-spectrum CBD oil, all the ingredients interact synergistically for a more actualized effect, resulting in the entourage effect(37).
- Broad-spectrum CBD oil products contain almost all of the cannabinoids in full-spectrum products. However, broad-spectrum CBD items do not have THC.
- CBD isolates contain only pure CBD. These products do not have THC or any other cannabinoids.
- Although the 2018 Farm Bill has legalized the production and sale of industrial hemp products, individuals should still research the legal provisions of the state where the CBD product will be purchased.
- Consumers must also prioritize buying only organic, non-GMO CBD products, as these are indicative of a product’s quality. Buyers may also choose gluten-free products as a lifestyle preference.
- Legitimate CBD companies and sellers should have a COA (certificate of analysis) and third-party lab testing reports for every batch of oil produced.
- Checking the product’s ingredients for any THC content is also necessary. THC should be less than 0.3%.
- Consumers should always check for product reviews and customer feedback of both the CBD product and CBD brand to gather information about the quality of the item.
- Customers must also consult a medical professional before adding CBD to their existing tinnitus treatment.
CBD Dosage for Tinnitus
There is no existing standard dosage chart or guidelines for CBD oil.
In several CBD studies, differing CBD dosage was also given to human subjects.
However, researchers noted that humans may tolerate a high dose (1500mg) of daily CBD(38).
The common practice among CBD users is to start with a small dose and gradually increase until the desired effect is reached.
Each CBD company has its dosage chart. When in doubt, individuals should follow the dosage instructions as provided in the CBD product. They should also consult a doctor, especially if they are first-time CBD users.
Specifically, tinnitus patients should also seek professional medical advice before administering CBD oil for tinnitus relief, as the product may interact negatively with other drugs taken alongside it.
How to Take CBD Oil for Tinnitus
Various CBD products are now available on the market, with each item having a different method of administration.
CBD oil tinctures, oil drops, and sprays are administered under the tongue. These products may also be mixed into food or drinks.
Individuals who are not fond of CBD’s natural and earthy taste can try flavored CBD oil products.
Manufacturers formulate CBD oil tinctures with carrier oils such as hempseed oil or coconut oil. Hempseed oil typically comes from hemp seeds and contain virtually no cannabinoids or CBD.
Edibles such as CBD gummies, chews, candies, and capsules are also available for those who want to explore other CBD administration methods.
When buying the best CBD gummies online, such as on Amazon, the customer should check the product’s COA and the brand’s authenticity to ensure the item is not fake or the transaction is not a scam.
Some CBD companies sell CBD vape juice and promote these products as an alternative to smoking. However, users should be wary of the health risks accompanying vaping(39).
As for the frequency of use, CBD oil is generally taken twice a day.
However, CBD oil, even those of the highest quality, is by no means a miracle cure or approved treatment for tinnitus and may not bring the expected tinnitus relief.
The best approach would be to consult with a medical professional before adding CBD oil as part of one’s daily regimen.
Conclusion
Tinnitus patients may look to CBD oil for tinnitus relief after recent human studies have shown tinnitus to be a form of sensory epilepsy.
However, there is a lack of scientific evidence to support CBD as an effective treatment for tinnitus.
One study has shown a 1:1 CBD and THC combination to aggravate tinnitus and not alleviate the hearing problem.
However, other medical professionals have recommended the use of CBD oil to mitigate feelings of anxiety and stress known to worsen tinnitus.
Further studies are needed to explore the effects of CBD on patients with tinnitus.
Individuals who have tinnitus or other health issues, such as migraines or chronic pain, should first seek the advice of a medical professional before the initial administration of CBD oil. Consumers planning to use CBD for weight loss, smoking cessation, or overall health and wellness should consult a fitness expert or dietician.
- Cannabinoids, Cannabinoid Receptors and Tinnitus https://doi.org/10.1016/j.heares.2015.09.014
- Ibid.
- Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials https://doi.org/10.3390/molecules24081459
- Cannabinoid CB1 Receptor Agonists Do Not Decrease, but may Increase Acoustic Trauma-Induced Tinnitus in Rats https://doi.org/10.3389/fneur.2015.00060
- Anxiety and depression in tinnitus patients: 5-year follow-up assessment after completion of habituation therapy https://doi.org/10.1155/2012/375460
- Cannabidiol as a Potential Treatment for Anxiety Disorders https://doi.org/10.1007/s13311-015-0387-1
- Tinnitus: Facts, Theories, and Treatments https://www.ncbi.nlm.nih.gov/books/NBK217855/
- Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials https://doi.org/10.3390/molecules24081459
- Tinnitus: Symptoms & Causes https://www.mayoclinic.org/diseases-conditions/tinnitus/symptoms-causes/syc-20350156
- Tinnitus https://www.audiology.org/consumers-and-patients/hearing-and-balance/tinnitus/
- MÉNIÈRE’S DISEASE https://vestibular.org/menieres-disease
- Tinnitus: Ringing in the Ears and What to Do About It https://www.health.harvard.edu/diseases-and-conditions/tinnitus-ringing-in-the-ears-and-what-to-do-about-it
- Ibid.
- Ibid.
- Physiology, Cochlear Function https://www.ncbi.nlm.nih.gov/books/NBK531483/
- Potent KCNQ2/3-Specific Channel Activator Suppresses In Vivo Epileptic Activity and Prevents the Development of Tinnitus https://doi.org/10.1523/JNEUROSCI.5176-14.2015
- Cannabinoids, Cannabinoid Receptors and Tinnitus https://doi.org/10.1016/j.heares.2015.09.014
- The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy https://doi.org/10.1124/jpet.103.051920
- Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials https://doi.org/10.3390/molecules24081459
- FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms
- Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective https://www.frontiersin.org/articles/10.3389/fneur.2020.505995/full
- Tetrahydrocannabinol https://www.sciencedirect.com/topics/neuroscience/tetrahydrocannabinol
- Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis sativa https://doi.org/10.2174/1871527313666140612114838
- Anxiety and Depression in Tinnitus Patients: 5-Year Follow-Up Assessment After Completion of Habituation Therapy https://doi.org/10.1155/2012/375460
- The Endocannabinoid System: Essential and Mysterious https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
- Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective https://www.frontiersin.org/articles/10.3389/fneur.2020.505995/full
- Cannabinoid CB1 Receptor Agonists Do Not Decrease, but may Increase Acoustic Trauma-Induced Tinnitus in Rats https://doi.org/10.3389/fneur.2015.00060
- WHO Expert Committee on Drug Dependence: Fortieth Report https://apps.who.int/iris/bitstream/handle/10665/279948/9789241210225-eng.pdf
- FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD) https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
- Cannabidiol as a Potential Treatment for Anxiety Disorders https://doi.org/10.1007/s13311-015-0387-1
- Cannabinoid CB1 Receptor Agonists Do Not Decrease, but May Increase Acoustic Trauma-Induced Tinnitus in Rats https://doi.org/10.3389/fneur.2015.00060
- An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies https://doi.org/10.1089/can.2016.0034
- What Are the Benefits of CBD — And Is It Safe to Use? https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
- Tinnitus: Ringing in the Ears and What to Do About It https://www.health.harvard.edu/diseases-and-conditions/tinnitus-ringing-in-the-ears-and-what-to-do-about-it
- Flavonoids as Antioxidants https://pubmed.ncbi.nlm.nih.gov/10924197/
- The Cannabis Terpenes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763918/
- CBD & Its Entourage https://www.projectcbd.org/cbd-its-entourage
- An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies https://doi.org/10.1089/can.2016.0034
- Can Vaping Damage Your Lungs? What We Do (and Don’t) Know https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
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