Can CBD Help Boost Fertility?
- Infertility is a common problem with men and women in the US. Around 6% to 12% of coupled women aged 15 to 44 have difficulty carrying pregnancy(1). About 8% of the male population also experience the same condition.
- CBD has anti-inflammatory and pain relief properties that may help with issues linked to the female reproductive system(2).
- However, CBD may bring negative effects to the male reproductive system(3). These effects include changes in sexual behavior, reduced testosterone levels, and decreased fertilization rates.
- Taking alternative treatments, like CBD, should be prescribed by an obstetrician-gynecologist before administration.
Best CBD Oils for Fertility
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD. Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes. Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits. cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
Specifically formulated to be more palatable to CBD users
Check Latest Prices
Overall Clinical Score 99%
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS Source Kentucky, USA & North Carolina, USA Form Oil Tincture Ingredients Organic Hemp Seed Oil, Full Spectrum CBD Oil Type Full Spectrum Extraction Moonshine extraction method How to take it Under tongue Potency 750 mg per bottle Carrier Oil Organic Hemp Seed Oil Concentration 25mg of CBD per dropper full (1ml) Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana Flavours Peppermint Price Range $89 ($75.65 for subscriptions, 15% discount from regular price) $/mg CBD $0.12/mg ($0.10/mg with subscription) Shipping 2-4 business days (first class USPS) Lab Tests Third Party Lab Tested post formulation for safety and potency, available on website Contaminants Organic, Non-GMO, no pesticides, no herbicides, no solvents or chemical fertilizers, No preservatives or sweeteners Allergens Vegan, Gluten free Refund policy Within 30 days Recommended for New CBD users Countries served USA only (all 50 states)
Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
Check Latest Prices
Overall Clinical Score 99%
Discount pricing available? 20% Off Coupon Code: CBDCLINICALS20 Source Colorado, USA Form Oil Tincture Ingredients Full Spectrum Hemp Extract, Organic Virgin Hemp Seed Oil Type Full Spectrum CBD Extraction CO2 Method How to take it Under the tongue for approximately 30 seconds before swallowing Potency 900mg per bottle Carrier Oil Organic Hemp Oil Concentration 60mg per dropper full (1ml) Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana Flavours Natural Price Range $99 - $434 $/mg CBD $0.08 - $0.13 Shipping 2-3 Days via USPS Lab Tests Third Party Lab Tested post formulation for safety and potency, available on website Contaminants No additives or preservatives, Non-GMO, NO herbicides, pesticides, or chemical fertilizers Allergens Not specified Refund policy Within 30 days Recommended for Health-conscious persons Countries served USA (all 50 states) and over 40 countries including Australia, Azerbaijan, Beliza, Bosnia & Herzegovina, Brazil, Chile, China, Croatia, Czech Republic, Estonia, France, Hong Kong, Hungary, Ireland, Israel, Japan, Latvia, Lebanon, Lithuania, Macao, Malaysia, Malta, Netherlands, New Zealand, Oman, Paraguay, Poland, Portugal, Saudi Arabia, Serbia, Singapore, South Korea, Sweden, Switzerland, United Arab Emirates, United Kingdom, Uruguay, and many more.
4x the strength of a regular cbd oil
Check Latest Prices
Overall Clinical Score 99%
Discount pricing available? 15% Off Coupon Code: CBDCLINICALS15 Source Colorado, USA Form Oil Tincture Ingredients Cannabidiol (CBD), Coconut Medium-chain triglycerides (MCT) Oil, Peppermint oil Type Broad Spectrum Extraction CO2-extraction How to take it Using 1-3 servings per day as needed is a good start to determine how much you need Potency 1000 mg per bottle Carrier Oil Coconut MCT Oil Concentration 33.5 mg per dropper (1ml) Drug Test Contains 0.3% THC but there is a chance you may test positive for marijuana Flavours Peppermint Price Range Single Bottle - $119.95, 2-Pack - $109.97 each, 3-Pack - $98.31 each, 6-Pack - $79.99 each $/mg CBD Single bottle - $0.010, 2-Pack - $0.011, 3-Pack - $0.009, 6-Pack - $0.007 Shipping 3-5 Business days Lab Tests Third Party Lab Tested post formulation for safety and potency, available on website Contaminants Contaminant-free Allergens Vegan and Gluten-free Refund policy Within 30 days Recommended for Patients who are looking for serious CBD oil support Countries served USA only (all 50 states)
Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
Check Latest Prices
Overall Clinical Score 99%
Discount pricing available? 15% Off Coupon Code: cbdMD15 Source Kentucky, USA Form Oil Tincture Ingredients Cannabidiol (CBD), MCT Oil, and Flavoring Type Broad Spectrum Extraction CO2 extraction method How to take it Under tongue Potency 1500mg per bottle Carrier Oil Organic Coconut MCT Oil Concentration 50mg per dropper full (1ml) Drug Test Containing less than 0.3% THC, there are still trace amounts Flavours Natural, Berry, Orange and Mint Price Range $99.99 $/mg CBD $0.07 Shipping 2-5 Business days (via Fedex) Lab Tests Third Party Lab Tested post formulation for safety and potency, available on website Contaminants 100% organic, non-GMO, and vegan-certified Allergens Vegan, Gluten free Refund policy Within 30 days Recommended for Daily CBD oil users Countries served USA only (all 50 states)
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
Why People Are Taking CBD for Fertility
Fertility is the reproductive capability of a person. The current fertility rate in the US is 1.77 births per woman(4). Infertility is a common problem with men and women in the US.
Approximately 6% to 12% of coupled women aged 15 to 44 have difficulty carrying a pregnancy to term(5). Men also sometimes have infertility issues.
Fertility treatments address these issues. These treatments include fertility drugs, assisted reproductive technologies (ART), and surgical treatments. However, while these treatments may boost fertility, they may also cause potential side effects.
A study showed a heightened risk of maternal death among pregnant women who used ART, specifically in vitro fertilization (IVF)(6). Unfortunately, the specific components of the treatment that may have increased the risks were not determined.
Treatments for male infertility also displayed side effects. Clomiphene citrate is a drug that can help increase sperm production in men. However, it may cause gastrointestinal distress, hair loss, gynecomastia (enlargement of male breasts), and weight gain(7).
CBD may attenuate infertility. The compound has shown its analgesic, anti-inflammatory, antiemetic, and anxiolytic (anti-anxiety) properties in different research findings(8). These properties may aid in alleviating the symptoms of gynecological disorders that may cause infertility.
How CBD Oil Works to Help with Reproductive Issues
CBD interacts with the body’s endocannabinoid system (ECS). This system plays an essential role in the body’s psychological functions, including reproduction(9).
The ECS has three main components: endocannabinoids, cannabinoid receptors, and enzymes. Endocannabinoids bind with the receptors and can elicit a specific response. Enzymes then break down the endocannabinoids after their function has been carried out.
CBD and THC are phytocannabinoids that can bind with receptors and activate their functions.
In a study on the male reproductive system, researchers noted that G-protein coupled receptors (GPR18) could activate an acrosome reaction(10). The reaction allows the sperm cell to penetrate the egg, allowing fertilization to happen.
Meanwhile, some female reproductive issues linked to infertility may be addressed with CBD’s impact on the ECS(11).
Polycystic ovarian syndrome (PCOS) can be linked with how the ECS works(12). In the condition, the uterus shows a decrease in fatty acid amide hydrolase (FAAH), the enzyme that breaks down the endocannabinoid anandamide (AEA).
AEA may aid in production of immature eggs leading to ovulation(13). AEA continues to produce eggs because FAAH levels are too low to function. Overproduction of immature eggs may appear as multiple cysts inside the ovaries, hence the condition.
PCOS is an ovulation disorder that causes hormonal imbalance in women. This condition is a common cause of a woman’s infertility(14).
Endometriosis is another reproductive issue that may account for a woman’s infertility. It occurs when the endometrium tissues, the lining of the uterus, grow out of the womb. This condition is characterized by chronic pain and inflammation.
CBD has anti-inflammatory and pain relief properties that may help in pain management in the female reproductive tract(15).
On the other hand, using CBD may negatively impact the male reproductive system(16). These effects include changes in sexual behavior, reduced sperm count, and decreased fertilization rates.
The mixed results of whether CBD can affect both sexes’ fertility may be best discussed with an obstetrician and gynecologist (ob/gyn).
The Pros and Cons of CBD Oil for Fertility
- CBD may help with pain and inflammation in the female reproductive system. These symptoms may contribute to female fertility issues.
- CBD may be purchased without a doctor’s prescription in states and territories where it is legalized.
- The World Health Organization (WHO) stated that CBD has no potential for abuse and dependence, making it a substance with a good safety profile(17).
- No direct studies have shown that CBD use can increase fertility. However, the US Food and Drug Administration (FDA) warns people about the compound’s use during pregnancy and breastfeeding(18). Using cannabis during pregnancy can cause problems with the fetus, like low birth weight(19) and abnormal brain development(20).
- CBD may decrease male fertility and cause changes in sexual behavior and sperm concentration.
- CBD can cause side effects, like diarrhea, fatigue, nausea, and drowsiness(21).
How CBD Oil Compares to Alternative Treatments for Fertility Issues
Treatment options, such as acupuncture and meditation, are widely practiced to increase fertility rates. Other herbal medicines and dietary supplements, like chasteberry extract, may be taken to improve the condition.
These practices are still subject to medical review to prove their contribution to the fertility rates(22).
CBD oil has no guaranteed effect on fertility rates.
How to Choose the Right CBD Oil
There are three types of CBD oil to choose from when it comes to CBD concentration.
The purest form of CBD are the isolates. Isolates are made of 99% pure CBD derived from hemp plants.
Broad-spectrum CBD oil contains all the cannabinoids in hemp without THC. It creates an entourage effect that gives the maximum health benefits of the compounds working together.
Full-spectrum CBD oil has all the compounds present in the hemp plant, including THC. Unlike CBD, THC causes psychoactive effects.
Although CBD products do not have a guaranteed effect on a person’s fertility, they can be used to ease pain and inflammation as studies suggest.
CBD Dosage for Fertility
CBD dosage varies depending on the severity of the condition, body weight, and body chemistry.
As a precautionary measure, CBD should be taken in small doses, around 12mg to 25mg per day. It may be increased gradually until the desired effect is achieved.
How to Take CBD Oil for Reproductive Issues
CBD products come in various forms.
CBD vape pens are used for a direct impact on the circulatory system. Vaping CBD oil is the fastest method that can be used to alleviate pain and inflammatory symptoms.
CBD suppositories can also be used for pain that concerns the uterus. These treatments are taken intravaginally and may target cramp relief and muscle relaxation.
Ingestibles, such as CBD gummies, oils, and tinctures, can be options for users who want a traditional administration. Tinctures can also be used sublingually for more direct absorption.
Infertility is a common problem for couples. It is a reproductive issue that can be found in both men and women.
While CBD is not a proven solution to increase fertility rates, it may alleviate pain and inflammatory symptoms of health conditions that may cause infertility.
Taking alternative treatments, like CBD, should be prescribed by an ob/gyn before administration.
- Centers for Disease Control and Prevention. (n.d.). Infertility | Reproductive Health | CDC. https://www.cdc.gov/reproductivehealth/infertility/index.htm
- P Cavner, J. (2019). Is CBD A Viable Option for Menstrual Symptoms? Online Journal of Complementary & Alternative Medicine, 2(5), 1–3.
- Carvalho, R. K., Andersen, M. L., & Mazaro‐Costa, R. (2019). The effects of cannabidiol on male reproductive system: A literature review. Journal of Applied Toxicology, 40(1), 132–150. https://doi.org/10.1002/jat.3831
- World Bank. (2018). Fertility rate, total (births per woman) – United States. https://data.worldbank.org/indicator/SP.DYN.TFRT.IN?locations=US
- Centers for Disease Control and Prevention. op. cit.
- Dayan, N., Joseph, K. S., Fell, D. B., Laskin, C. A., Basso, O., Park, A. L., Luo, J., Guan, J., & Ray, J. G. (2019). Infertility treatment and risk of severe maternal morbidity: a propensity score-matched cohort study. CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne, 191(5), E118–E127. https://doi.org/10.1503/cmaj.181124
- Khourdaji, I., Lee, H., & Smith, R. P. (2018). Frontiers in hormone therapy for male infertility. Translational Andrology and Urology, 7(S3), S353–S366. https://doi.org/10.21037/tau.2018.04.03
- Zhornitsky, S., & Potvin, S. (2012). Cannabidiol in humans-the quest for therapeutic targets. Pharmaceuticals (Basel, Switzerland), 5(5), 529–552. https://doi.org/10.3390/ph5050529
- Meccariello, R., Battista, N., Bradshaw, H. B., & Wang, H. (2014). Updates in Reproduction Coming from the Endocannabinoid System. International Journal of Endocrinology, 2014, 1–16. https://doi.org/10.1155/2014/412354
- Flegel, C., Vogel, F., Hofreuter, A. et al. Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18. Sci Rep 6, 32255 (2016). https://doi.org/10.1038/srep32255
- Luschnig, P., & Schicho, R. (2019). Cannabinoids in Gynecological Diseases. Medical Cannabis and Cannabinoids, 2(1), 14–21. https://doi.org/10.1159/000499164
- Walker, O. S., Holloway, A. C., & Raha, S. (2019). The role of the endocannabinoid system in female reproductive tissues. Journal of ovarian research, 12(1), 3. https://doi.org/10.1186/s13048-018-0478-9
- Melo, A. S., Ferriani, R. A., & Navarro, P. A. (2015). Treatment of infertility in women with polycystic ovary syndrome: approach to clinical practice. Clinics (Sao Paulo, Brazil), 70(11), 765–769. https://doi.org/10.6061/clinics/2015(11)09
- P Cavner, J. op. cit.
- Cacciola, G., Chianese, R., Chioccarelli, T., Ciaramella, V., Fasano, S., Pierantoni, R., Meccariello, R., & Cobellis, G. (2010). Cannabinoids and Reproduction: A Lasting and Intriguing History. Pharmaceuticals, 3(10), 3275–3323. https://doi.org/10.3390/ph3103275
- World Health Organization. (2018). Cannabidiol (CBD) Critical Review Report. https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
- U.S. Food and Drug Administration. (2019, October 16). What You Should Know About Using CBD When Pregnant or Breastfeeding. https://www.fda.gov/consumers/consumer-updates/what-you-should-know-about-using-cannabis-including-cbd-when-pregnant-or-breastfeeding#2
- Gunn JK, Rosales CB, Center KE, Nuñez A, Gibson SJ, Christ C, Ehiri JE.”Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis.” 2016 Apr 5;6(4):e009986. doi: 10.1136/bmjopen-2015-009986.
- Chia-Shan Wu, Christopher P Jew, and Hui-Chen Lu. “Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain.” Future Neurol. 2011 Jul 1; 6(4): 459–480.
- Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects and Toxicity. Current neuropharmacology, 17(10), 974–989. https://doi.org/10.2174/1570159X17666190603171901
- Miner, S. A., Robins, S., Zhu, Y. J., Keeren, K., Gu, V., Read, S. C., & Zelkowitz, P. (2018). Evidence for the use of complementary and alternative medicines during fertility treatment: a scoping review. BMC complementary and alternative medicine, 18(1), 158. https://doi.org/10.1186/s12906-018-2224-7