Can CBD Help Boost Fertility?

  • Infertility is a common problem with men and women in the US. Around 6% to 12% of coupled women aged 15 to 44 have difficulty carrying pregnancy(1). About 8% of the male population also experience the same condition.
  • CBD has anti-inflammatory and pain relief properties that may help with issues linked to the female reproductive system(2).
  • However, CBD may bring negative effects to the male reproductive system(3). These effects include changes in sexual behavior, reduced testosterone levels, and decreased fertilization rates.
  • Taking alternative treatments, like CBD, should be prescribed by an obstetrician-gynecologist before administration.

Best CBD Oils for Fertility

Editor's Pick

Spruce 750mg Lab Grade CBD Oil

Specifically formulated to be more palatable to CBD users
Spruce 750mg Lab Grade CBD Oil Bottle
  • Overall Clinical Score
    99%
    Editor's Pick
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

    Pro's
    Cons's
    •  Mid-strength
    •  Natural peppermint flavor
    •  Made from 100% organic and natural ingredients
    •  No other flavors
  • Features
    Discount pricing available?20% Off Coupon Code: CBDCLINICALS
    Source
    Source of Hemp
    Kentucky, USA & North Carolina, USA
    FormOil Tincture
    IngredientsOrganic Hemp Seed Oil, Full Spectrum CBD Oil
    Type
    Type of CBD
    Full Spectrum
    Extraction
    Extraction Method
    Moonshine extraction method
    How to take itUnder tongue
    Potency
    Potency - CBD Per Bottle
    750 mg per bottle
    Carrier OilOrganic Hemp Seed Oil
    Concentration
    CBD Concentration Per Serving
    25mg of CBD per dropper full (1ml)
    Drug TestContains 0.3% THC but there is a chance you may test positive for marijuana
    FlavoursPeppermint
    Price Range$89 ($75.65 for subscriptions, 15% discount from regular price)
    $/mg CBD
    Price ($/mg)
    $0.12/mg ($0.10/mg with subscription)
    Shipping
    Shipping/Time to delivery
    2-4 business days (first class USPS)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsOrganic, Non-GMO, no pesticides, no herbicides, no solvents or chemical fertilizers, No preservatives or sweeteners
    AllergensVegan, Gluten free
    Refund policyWithin 30 days
    Recommended forNew CBD users
    Countries servedUSA only (all 50 states)
Check Latest Prices

Best Organic

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  • Overall Clinical Score
    99%
    Best Organic
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

    Pro's
    Cons's
    •  Pure CBD hemp
    •  All natural
    •  Approximately 300 drops total
    •  No other flavors
  • Features
    Discount pricing available?20% Off Coupon Code: CBDCLINICALS20
    Source
    Source of Hemp
    Colorado, USA
    FormOil Tincture
    IngredientsFull Spectrum Hemp Extract, Organic Virgin Hemp Seed Oil
    Type
    Type of CBD
    Full Spectrum CBD
    Extraction
    Extraction Method
    CO2 Method
    How to take itUnder the tongue for approximately 30 seconds before swallowing
    Potency
    Potency - CBD Per Bottle
    900mg per bottle
    Carrier OilOrganic Hemp Oil
    Concentration
    CBD Concentration Per Serving
    60mg per dropper full (1ml)
    Drug TestContains 0.3% THC but there is a chance you may test positive for marijuana
    FlavoursNatural
    Price Range$99 - $434
    $/mg CBD
    Price ($/mg)
    $0.08 - $0.13
    Shipping
    Shipping/Time to delivery
    2-3 Days via USPS
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsNo additives or preservatives, Non-GMO, NO herbicides, pesticides, or chemical fertilizers
    AllergensNot specified
    Refund policyWithin 30 days
    Recommended forHealth-conscious persons
    Countries servedUSA (all 50 states) and over 40 countries including Australia, Azerbaijan, Beliza, Bosnia & Herzegovina, Brazil, Chile, China, Croatia, Czech Republic, Estonia, France, Hong Kong, Hungary, Ireland, Israel, Japan, Latvia, Lebanon, Lithuania, Macao, Malaysia, Malta, Netherlands, New Zealand, Oman, Paraguay, Poland, Portugal, Saudi Arabia, Serbia, Singapore, South Korea, Sweden, Switzerland, United Arab Emirates, United Kingdom, Uruguay, and many more.
Check Latest Prices

Best Customer Service

Sabaidee Super Good Vibes CBD Oil

4x the strength of a regular cbd oil
Sabaidee Super Good Vibes CBD Oil
  • Overall Clinical Score
    99%
    Best Customer Service
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.

    Pro's
    Cons's
    •  Extra strong
    •  Significant benefits with just a few drops
    •  100% Natural ingredients
    •  No other flavors
  • Features
    Discount pricing available?15% Off Coupon Code: CBDCLINICALS15
    Source
    Source of Hemp
    Colorado, USA
    FormOil Tincture
    IngredientsCannabidiol (CBD), Coconut Medium-chain triglycerides (MCT) Oil, Peppermint oil
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2-extraction
    How to take itUsing 1-3 servings per day as needed is a good start to determine how much you need
    Potency
    Potency - CBD Per Bottle
    1000 mg per bottle
    Carrier OilCoconut MCT Oil
    Concentration
    CBD Concentration Per Serving
    33.5 mg per dropper (1ml)
    Drug TestContains 0.3% THC but there is a chance you may test positive for marijuana
    FlavoursPeppermint
    Price RangeSingle Bottle - $119.95, 2-Pack - $109.97 each, 3-Pack - $98.31 each, 6-Pack - $79.99 each
    $/mg CBD
    Price ($/mg)
    Single bottle - $0.010, 2-Pack - $0.011, 3-Pack - $0.009, 6-Pack - $0.007
    Shipping
    Shipping/Time to delivery
    3-5 Business days
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    ContaminantsContaminant-free
    AllergensVegan and Gluten-free
    Refund policyWithin 30 days
    Recommended forPatients who are looking for serious CBD oil support
    Countries servedUSA only (all 50 states)
Check Latest Prices

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg

Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
cbdMD CBD Oil Tincture Natural 1500mg
  • Overall Clinical Score
    99%
    Best Natural Alternative
  • Score breakdown
    Value
    Quality
    Strength
    Customer Service
    Lab Testing Transparency
    Effectiveness
  • Summary

    cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

    Pro's
    Cons's
    •  Various delicious flavors to choose from
    •  Has vegan, organic, and gluten-free ingredients
    •  Free shipping for this particular product within USA
    •  World-class customer service team
    •  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
  • Features
    Discount pricing available?15% Off Coupon Code: cbdMD15
    Source
    Source of Hemp
    Kentucky, USA
    FormOil Tincture
    IngredientsCannabidiol (CBD), MCT Oil, and Flavoring
    Type
    Type of CBD
    Broad Spectrum
    Extraction
    Extraction Method
    CO2 extraction method
    How to take itUnder tongue
    Potency
    Potency - CBD Per Bottle
    1500mg per bottle
    Carrier OilOrganic Coconut MCT Oil
    Concentration
    CBD Concentration Per Serving
    50mg per dropper full (1ml)
    Drug TestContaining less than 0.3% THC, there are still trace amounts
    FlavoursNatural, Berry, Orange and Mint
    Price Range$99.99
    $/mg CBD
    Price ($/mg)
    $0.07
    Shipping
    Shipping/Time to delivery
    2-5 Business days (via Fedex)
    Lab Tests
    Lab Testing Transparency
    Third Party Lab Tested post formulation for safety and potency, available on website
    Contaminants100% organic, non-GMO, and vegan-certified
    AllergensVegan, Gluten free
    Refund policyWithin 30 days
    Recommended forDaily CBD oil users
    Countries servedUSA only (all 50 states)
Check Latest Prices

Why People Are Taking CBD for Fertility

Fertility is the reproductive capability of a person. The current fertility rate in the US is 1.77 births per woman(4). Infertility is a common problem with men and women in the US. 

Approximately 6% to 12% of coupled women aged 15 to 44 have difficulty carrying a pregnancy to term(5). Men also sometimes have infertility issues.

Fertility treatments address these issues. These treatments include fertility drugs, assisted reproductive technologies (ART), and surgical treatments. However, while these treatments may boost fertility, they may also cause potential side effects.

A study showed a heightened risk of maternal death among pregnant women who used ART, specifically in vitro fertilization (IVF)(6). Unfortunately, the specific components of the treatment that may have increased the risks were not determined.

Treatments for male infertility also displayed side effects. Clomiphene citrate is a drug that can help increase sperm production in men. However, it may cause gastrointestinal distress, hair loss, gynecomastia (enlargement of male breasts), and weight gain(7)

CBD may attenuate infertility. The compound has shown its analgesic, anti-inflammatory, antiemetic, and anxiolytic (anti-anxiety) properties in different research findings(8). These properties may aid in alleviating the symptoms of gynecological disorders that may cause infertility.

How CBD Oil Works to Help with Reproductive Issues

CBD interacts with the body’s endocannabinoid system (ECS). This system plays an essential role in the body’s psychological functions, including reproduction(9).

The ECS has three main components: endocannabinoids, cannabinoid receptors, and enzymes. Endocannabinoids bind with the receptors and can elicit a specific response. Enzymes then break down the endocannabinoids after their function has been carried out.

CBD and THC are phytocannabinoids that can bind with receptors and activate their functions.

In a study on the male reproductive system, researchers noted that G-protein coupled receptors (GPR18) could activate an acrosome reaction(10). The reaction allows the sperm cell to penetrate the egg, allowing fertilization to happen. 

Meanwhile, some female reproductive issues linked to infertility may be addressed with CBD’s impact on the ECS(11)

Polycystic ovarian syndrome (PCOS) can be linked with how the ECS works(12). In the condition, the uterus shows a decrease in fatty acid amide hydrolase (FAAH), the enzyme that breaks down the endocannabinoid anandamide (AEA). 

AEA may aid in production of immature eggs leading to ovulation(13). AEA continues to produce eggs because FAAH levels are too low to function. Overproduction of immature eggs may appear as multiple cysts inside the ovaries, hence the condition.

PCOS is an ovulation disorder that causes hormonal imbalance in women. This condition is a common cause of a woman’s infertility(14)

Endometriosis is another reproductive issue that may account for a woman’s infertility. It occurs when the endometrium tissues, the lining of the uterus, grow out of the womb. This condition is characterized by chronic pain and inflammation.

CBD has anti-inflammatory and pain relief properties that may help in pain management in the female reproductive tract(15)

On the other hand, using CBD may negatively impact the male reproductive system(16). These effects include changes in sexual behavior, reduced sperm count, and decreased fertilization rates.

The mixed results of whether CBD can affect both sexes’ fertility may be best discussed with an obstetrician and gynecologist (ob/gyn).

The Pros and Cons of CBD Oil for Fertility

The Pros

  • CBD may help with pain and inflammation in the female reproductive system. These symptoms may contribute to female fertility issues.
  • CBD may be purchased without a doctor’s prescription in states and territories where it is legalized.
  • The World Health Organization (WHO) stated that CBD has no potential for abuse and dependence, making it a substance with a good safety profile(17).

The Cons

  • No direct studies have shown that CBD use can increase fertility. However, the US Food and Drug Administration (FDA) warns people about the compound’s use during pregnancy and breastfeeding(18). Using cannabis during pregnancy can cause problems with the fetus, like low birth weight(19) and abnormal brain development(20).
  • CBD may decrease male fertility and cause changes in sexual behavior and sperm concentration
  • CBD can cause side effects, like diarrhea, fatigue, nausea, and drowsiness(21).

How CBD Oil Compares to Alternative Treatments for Fertility Issues

Treatment options, such as acupuncture and meditation, are widely practiced to increase fertility rates. Other herbal medicines and dietary supplements, like chasteberry extract, may be taken to improve the condition.

These practices are still subject to medical review to prove their contribution to the fertility rates(22).

CBD oil has no guaranteed effect on fertility rates. 

How to Choose the Right CBD Oil 

There are three types of CBD oil to choose from when it comes to CBD concentration.

The purest form of CBD are the isolates. Isolates are made of 99% pure CBD derived from hemp plants.

Broad-spectrum CBD oil contains all the cannabinoids in hemp without THC. It creates an entourage effect that gives the maximum health benefits of the compounds working together.

Full-spectrum CBD oil has all the compounds present in the hemp plant, including THC. Unlike CBD, THC causes psychoactive effects.

Although CBD products do not have a guaranteed effect on a person’s fertility, they can be used to ease pain and inflammation as studies suggest.

CBD Dosage for Fertility

CBD dosage varies depending on the severity of the condition, body weight, and body chemistry. 

As a precautionary measure, CBD should be taken in small doses, around 12mg to 25mg per day. It may be increased gradually until the desired effect is achieved. 

How to Take CBD Oil for Reproductive Issues

CBD products come in various forms. 

CBD vape pens are used for a direct impact on the circulatory system. Vaping CBD oil is the fastest method that can be used to alleviate pain and inflammatory symptoms.

CBD suppositories can also be used for pain that concerns the uterus. These treatments are taken intravaginally and may target cramp relief and muscle relaxation. 

Ingestibles, such as CBD gummies, oils, and tinctures, can be options for users who want a traditional administration. Tinctures can also be used sublingually for more direct absorption.

Conclusion

Infertility is a common problem for couples. It is a reproductive issue that can be found in both men and women.

While CBD is not a proven solution to increase fertility rates, it may alleviate pain and inflammatory symptoms of health conditions that may cause infertility. 

Taking alternative treatments, like CBD, should be prescribed by an ob/gyn before administration. 


  1. Centers for Disease Control and Prevention. (n.d.). Infertility | Reproductive Health | CDC. https://www.cdc.gov/reproductivehealth/infertility/index.htm
  2. P Cavner, J. (2019). Is CBD A Viable Option for Menstrual Symptoms? Online Journal of Complementary & Alternative Medicine, 2(5), 1–3. 
  3. Carvalho, R. K., Andersen, M. L., & Mazaro‐Costa, R. (2019). The effects of cannabidiol on male reproductive system: A literature review. Journal of Applied Toxicology, 40(1), 132–150. https://doi.org/10.1002/jat.3831
  4. World Bank. (2018). Fertility rate, total (births per woman) – United States. https://data.worldbank.org/indicator/SP.DYN.TFRT.IN?locations=US
  5. Centers for Disease Control and Prevention. op. cit.
  6. Dayan, N., Joseph, K. S., Fell, D. B., Laskin, C. A., Basso, O., Park, A. L., Luo, J., Guan, J., & Ray, J. G. (2019). Infertility treatment and risk of severe maternal morbidity: a propensity score-matched cohort study. CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne, 191(5), E118–E127. https://doi.org/10.1503/cmaj.181124
  7. Khourdaji, I., Lee, H., & Smith, R. P. (2018). Frontiers in hormone therapy for male infertility. Translational Andrology and Urology, 7(S3), S353–S366. https://doi.org/10.21037/tau.2018.04.03
  8. Zhornitsky, S., & Potvin, S. (2012). Cannabidiol in humans-the quest for therapeutic targets. Pharmaceuticals (Basel, Switzerland), 5(5), 529–552. https://doi.org/10.3390/ph5050529
  9. Meccariello, R., Battista, N., Bradshaw, H. B., & Wang, H. (2014). Updates in Reproduction Coming from the Endocannabinoid System. International Journal of Endocrinology, 2014, 1–16. https://doi.org/10.1155/2014/412354
  10. Flegel, C., Vogel, F., Hofreuter, A. et al. Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18. Sci Rep 6, 32255 (2016). https://doi.org/10.1038/srep32255
  11. Luschnig, P., & Schicho, R. (2019). Cannabinoids in Gynecological Diseases. Medical Cannabis and Cannabinoids, 2(1), 14–21. https://doi.org/10.1159/000499164
  12. Walker, O. S., Holloway, A. C., & Raha, S. (2019). The role of the endocannabinoid system in female reproductive tissues. Journal of ovarian research, 12(1), 3. https://doi.org/10.1186/s13048-018-0478-9
  13. Ibid.
  14. Melo, A. S., Ferriani, R. A., & Navarro, P. A. (2015). Treatment of infertility in women with polycystic ovary syndrome: approach to clinical practice. Clinics (Sao Paulo, Brazil), 70(11), 765–769. https://doi.org/10.6061/clinics/2015(11)09
  15. P Cavner, J. op. cit. 
  16. Cacciola, G., Chianese, R., Chioccarelli, T., Ciaramella, V., Fasano, S., Pierantoni, R., Meccariello, R., & Cobellis, G. (2010). Cannabinoids and Reproduction: A Lasting and Intriguing History. Pharmaceuticals, 3(10), 3275–3323. https://doi.org/10.3390/ph3103275
  17. World Health Organization. (2018). Cannabidiol (CBD) Critical Review Report. https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  18. U.S. Food and Drug Administration. (2019, October 16). What You Should Know About Using CBD When Pregnant or Breastfeeding. https://www.fda.gov/consumers/consumer-updates/what-you-should-know-about-using-cannabis-including-cbd-when-pregnant-or-breastfeeding#2
  19. Gunn JK, Rosales CB, Center KE, Nuñez A, Gibson SJ, Christ C, Ehiri JE.”Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis.” 2016 Apr 5;6(4):e009986. doi: 10.1136/bmjopen-2015-009986.
  20. Chia-Shan Wu, Christopher P Jew, and Hui-Chen Lu. “Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain.” Future Neurol. 2011 Jul 1; 6(4): 459–480.
  21. Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects and Toxicity. Current neuropharmacology, 17(10), 974–989. https://doi.org/10.2174/1570159X17666190603171901
  22. Miner, S. A., Robins, S., Zhu, Y. J., Keeren, K., Gu, V., Read, S. C., & Zelkowitz, P. (2018). Evidence for the use of complementary and alternative medicines during fertility treatment: a scoping review. BMC complementary and alternative medicine, 18(1), 158. https://doi.org/10.1186/s12906-018-2224-7
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