Best CBD Oil for Dogs With Arthritis

Does your dog have arthritis? Find out how you can choose the best cannabidiol (CBD) products to help your arthritic dog improve its overall wellness and quality of life

Rating
Highlights

Editor's Choice

Spruce Dog CBD Oil 750mg

4.8 out of 5
  1. Has coconut oil as carrier which is generally easier on dogs
  2. Has milder taste and no flavorings
  3. Easy to use just sprinkle on dog’s food twice daily

Best CBD OIl For Dogs

Honest Paws Wellness Oil for Dogs

4.1 out of 5
  1. Calming,
  2. Full Spectrum
  3. Contains other natural ingredients to boost immunity

Best High Potency

Nuleaf Naturals Pet CBD Oil

5 out of 5
  1. Concentrated to approximately 50mg CBD per ml of oil
  2. Great for cats, dogs and other four-legged friends
  3. Can also be used by humans

Best High Potency

4 Corners Cannabis Pet Tincture

5 out of 5
  1. Generous on their options
  2. Different sizes and strengths available for your needs
  3. The flavor peanut butter is available perfect for pets who are picky when it comes to eating

Best Transparency

cbdMD Pet CBD Oil Tincture for Dogs

3.6 out of 5
  1. Uses hemp grown through organic farming methods.
  2. Contains CBD Oil and MCT Oil only
  3. With two yummy flavors
Show Pros and Cons Ezoicreport this ad

Best CBD Oil for Dogs with Arthritis 2022

  1. Spruce Dog CBD Oil 750mg Best Overall
  2. Honest Paws Wellness Oil for Dogs Best Immunity Support for Dogs
  3. Nuleaf Naturals Pet CBD Oil Best Organic
  4. 4 Corners Cannabis Pet Tincture Best High Potency
  5. cbdMD Pet CBD Oil Tincture for Dogs Best Range


Compare the Best CBD for Dogs with Arthritis in 2022

ProductPotencyPurityCustomer ServiceTypeExtractionTransparencyAbsorption
Spruce Dog CBD Oil 750mg
4.8 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Honest Paws Wellness Oil for Dogs
4.1 out of 5
1.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Nuleaf Naturals Pet CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
4 Corners Cannabis Pet Tincture
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
3.0 out of 5
5.0 out of 5
cbdMD Pet CBD Oil Tincture for Dogs
3.6 out of 5
1.0 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5

Best CBD Oil for Dogs With Arthritis

1. Spruce Dog CBD Oil 750mg
cbdc overall score

4.8

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Same as human lab grade, full spectrum CBD oil

No other flavors

Easier on Dog's digestion

Made from 100% organic and natural ingredients

Overview

Spruce’s dog-friendly CBD has been specially formulated for dogs. Instead of hemp seed oil for the carrier oil, the product contains coconut oil, which is generally easier on the digestion for dogs. The taste is also milder with no flavorings, making it more likely that dogs will eat it with their food.

Using Spruce CBD for dogs is simple. All owners have to do is sprinkle the desired dose on the dog’s food at mealtime once or twice a day. Each dose should consist of about two to three drops per 20 pounds of dog weight.

2. Honest Paws Wellness Oil for Dogs
cbdc overall score

4.1

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Product offering is extensive

Most products were not tested for solvents or mycotoxins

Products are made from 100% organic, non-GMO, and locally grown hemp

Limited information on the company

30-day money-back guarantee

Available in the US only

Free shipping for orders over $49.95

Expedited delivery option is available

Overview

A calming full-spectrum hemp oil that combines naturally occurring CBD with other ingredients for healthy immunity, calm moods, and a healthy brain.

3. Nuleaf Naturals Pet CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Pure CBD hemp

No other flavors

All natural

Overview

CBD for dogs, cats and other four-legged friends! Our product is concentrated to approximately 50mg cannabinoids per milliliter of oil. While this product is designed for pets, it’s great for humans, too.

4. 4 Corners Cannabis Pet Tincture
cbdc overall score

5.0

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Has a wide variety of CBD strengths

A bit expensive

Free shipping on $100 and up

Incomplete lab test results

Overview

4 Corners Cannabis Pet Tinctures are generous on their options since there are different sizes and strengths available for you exact needs. The flavor peanut butter is available perfect for pets who are picky when it comes to eating.

5. cbdMD Pet CBD Oil Tincture for Dogs
cbdc overall score

3.6

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Same CBD Oil benefits as for humans

Low terpene and cannabinoid profile

No THC Animal-specific products (dogs, cats, horses)

Made from premium CBD from non-GMO USA hemp

Overview

With nothing but MCT oil combined with CBD oil sourced from U.S. hemp that is grown using organic farming methods, these CBD Oil Tinctures for Dogs can be added to their favorite foods while still providing the same effects that you enjoy. We have two flavors to choose from: Natural and Peanut Butter.

How CBD Helps Dogs With Arthritis 

A study from the Frontiers in Veterinary Science hypothesized that CBD may help with canine osteoarthritis (OA)(1). Osteoarthritis is a type of arthritis common in canines(2)

Cannabidiol or CBD is a compound found in hemp and cannabis(3). It has combined anti-inflammatory and immunosuppressive actions(4). Thus, it may be promising for chronic pain such as dog’s arthritis

CBD has structural similarities to tetrahydrocannabinol (THC). Nonetheless, CBD is non-psychoactive. Thus, it does not cause euphoria, unlike THC(5)

Cannabidiol interacts with the endocannabinoid system (ECS). The ECS is pervasive in mammalian species and is responsible for maintaining homeostasis(6)

Homeostasis is a process that living things use to sustain a stable condition while adjusting to changing external environments(7)

The process is done through a negative feedback loop that releases the endocannabinoids as they target the cannabinoid (CBD) receptors(8)

These cannabinoid receptors, known as CB1 and CB2, are found on cells throughout the body(9).

 CB2 receptors function primarily to modulate a healthy response to inflammation by regulating multiple anti-inflammatory pathways(10).  

An animal study posted in the Proceedings of the National Academy of Sciences of the United States of America examined cannabidiol’s effect on murine collagen-induced arthritis (CIA).  

The animal study results showed that cannabidiol, combined with anti-inflammatory and immunosuppressive actions, may have a potent anti-arthritic effect on CIA(11)

Meanwhile, Cornell University examined CBD’s effect on dogs with osteoarthritis. The study involved a small number of canines with OA that received 2mg of CBD per kilogram of body weight(12).  

The result showed that the dogs administered with CBD were perceived to be more comfortable and active than those given a placebo.  

Thus, the researchers hypothesized that cannabidiol may improve the level of comfort and morbidity of osteoarthritic dogs(13).   

The short-term effects of CBD appear to be positive in this particular study. Still, further long-term research with a larger population is necessary to determine CBD’s therapeutic effect on canine arthritis.  

Benefits of Using CBD on Dogs With Arthritis 

A 2019 animal study published in Multidisciplinary Digital Publishing Institute (MDPI) determined that an oral CBD-rich hemp supplement may not be detrimental to dogs(14)

Thus, you may administer CBD to your canine companion. 

Another research from the Pain Management in Veterinary Clinical Practice featured dogs administered with oral transmucosal cannabidiol with an anti-inflammatory substance. The animal subjects exhibited an improved canine BPI or canine brief pain inventory score(15).  

Canine BPI allows pet parents to measure their dog’s pain(16)

When your dog develops osteoarthritis, the treatment usually focuses on controlling pain, reducing inflammation, and improving your dog’s quality of life(17).

According to Jerry Klein, the chief veterinary officer at American Kennel Club (AKC), cannabidiol is used in dogs due to its potential anti-inflammatory properties, cardiac benefits, anti-nausea effects, anti-anxiety impact, and appetite stimulation(18).   

A study published in 2021 provided the first evidence of the immunomodulatory effect of cannabidiol in stimulated whole dog blood(19).

The result of the study demonstrated that CBD may reduce the inflammatory response induced by lipopolysaccharides (LPS). 

LPS is a glycolipid produced by most Gram-negative bacteria that can stimulate the immune system. 

LPS creates a permeability barrier at the cell surface. Furthermore, it is the main contributor to the innate resistance that Gram-negative bacteria exhibit against numerous antimicrobials(20)

The researchers of the 2021 study hypothesized that CBD may modulate cytokine production stimulated by LPS. 

Cytokines are the small glycoproteins essential in the inflammatory process.

Thus, cannabidiol may reduce the inflammatory response of dogs, as seen in the group administered with 50 and 100ml of CBD(21)

However, due to the lack of information and research on the use of cannabidiol in canines, the researchers suggested further studies to fully comprehend the possible therapeutic role of CBD in veterinary medicine(22)

Osteoarthritis is common among senior dogs and large breeds(23)

When your dog has OA, its cartilage cushion that allows joints to move smoothly begins to break down. It may be due to certain factors, such as age, repetitive stress, or injury. 

The deterioration of this protective cushion usually results in pain and inflammation(24)

CBD has purported anti-inflammatory properties(25). Therefore, the compound may have a good effect on dogs with osteoarthritis. 

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate chronic pain triggered by OA. However, these substances have significant side effects with continued use(26).  

On the other hand, a study from the American Journal of Veterinary Research noted that CBD administration was well tolerated by canines(27).  

Still, for your dog’s safety, make sure to speak with your veterinarian first. Generally, veterinarians in the U.S. are not allowed to prescribe CBD to their patients(28)

However, if you are from Nevada, licensed veterinarians can assist you in knowing the right amount of CBD appropriate for your arthritic dog.

Nevada is the first state to recognize cannabinoids, such as CBD, as a veterinary treatment(29).  

How Long Does CBD Take to Help Dogs With Arthritis?

The simplest way to administer CBD to your dog with arthritis is by adding CBD oil to its food or drinks(30).

Most CBD oil tincture products come with calibrated droppers. You may use them to dispense the oil or tincture on your dog’s food

Generally, the onset of CBD takes about 30 minutes. Your dog should feel the effects of CBD between four and six hours(31).    

On the contrary, CBD dog treats, such as biscuits and soft chews, have an average onset time of 30 to 90 minutes after consumption(32).   

If you own a larger dog, you may need to administer higher doses of cannabidiol for the compound to take effect(33)

How Long Will CBD Help Dogs With Arthritis?  

No study has determined how long cannabidiol takes to help dogs with arthritis.

Nevertheless, reports indicated that CBD has low bioavailability when administered orally to dogs and humans alike. This phenomenon is due to the high first-pass effect through the liver(34)

Bioavailability is the extent to which a substance becomes entirely available to one’s system(35). In this case, CBD’s intended biological destination is a dog’s body

A study from the Canadian Journal of Veterinary Research demonstrated that a CBD-infused oil formulation had the highest systemic exposures and half-life after administering 75mg and 150mg doses to healthy dogs(36)

The other delivery methods involved in the study include the administration of oral microencapsulated oil beads and CBD-infused transdermal cream.

Half-life is the length of time required for a drug concentration to decrease by 50% of its starting dosage in the body(37).   

Risks and Side Effects of Using CBD on Dogs With Arthritis

According to American Kennel Club, CBD may cause some side effects on dogs, such as(38):

  1. Dry mouth: cannabidiol may decrease saliva production. Thus, dogs may become thirstier.
  2. Drowsiness: CBD’s calming effects may cause your dog to be slightly drowsy, especially when you administer high doses.
  1. Lowered blood pressure: High doses of cannabidiol may cause a temporary drop in blood pressure, resulting in light-headedness. 

Ways to Choose the Best CBD Oil for Dogs With Arthritis

Most CBD companies advertise the best CBD products to their customers. Some even offer a money-back guarantee if their products do not deliver as promised.

On the other hand, other CBD brands promote CBD as a product for pain relief and even claim that it can improve joint health.  

If you are eager in finding the best CBD oils for dogs with arthritis, below are some pertinent information to help you select the appropriate CBD hemp oil product:

  1. If you know veterinarians experienced in cannabis use, make sure to consult them regarding CBD administration. Talking with an expert is necessary, especially if you consider giving your dog CBD for the first time. 

However, remember that most veterinarians in the U.S. cannot administer CBD to their patients under the current federal law. Still, you should be comfortable bringing it up(39)

  1. Opt for CBD oil products that are derived from organic hemp. If possible, go for products that are non-GMO, gluten-free, or contain natural ingredients

Most CBD companies grow hemp plants from their farms. Grown hemp must not contain more than 0.3% of THC(40)

Visit their website to verify if there is any information about their farming and CBD extraction methods

  1. Go for high-quality CBD oil products that utilize the CO2 extraction method. This process uses compressed carbon dioxide as the extraction solvent, avoiding flammable and toxic chemicals(41).   
  2. Make sure a third-party lab tests the brand’s CBD products. They should include the report on their website as well as the certificates of analysis (CoAs). 

Note that testing of CBD products is vital to ensure that they do not contain preservatives, heavy metals, pesticides, herbicides, residual solvents, and other harmful contaminants.

  1. Compare the CoA with the brand’s claims. Make sure that the amount of CBD in the product is accurate. 

Dogs have more endocannabinoid receptors in their cerebellum and brainstem than humans. These parts of the brain control heart and respiratory rates and coordination. 

Aside from having numerous endocannabinoid receptors, dogs are notably smaller than humans. Thus, they are more susceptible to toxicity from excessive THC consumption(42).  

For these reasons, go for THC-free CBD products if you think of giving CBD to your arthritic dog. 

  1. Make sure to understand different state laws regarding cannabis use. This way, you can avoid legal repercussions. 
  2. Know the different hemp extracts and decide which one suits your dog’s needs. The American Kennel Club suggested opting for broad-spectrum CBD oil over full-spectrum CBD oil for your pet(43)

The reason why you should avoid full-spectrum hemp extract for your dog is due to its THC content. 

Meanwhile, broad-spectrum products contain terpenes and cannabinoids found in the cannabis plant. However, they do not have THC(44)

Some brands may also offer CBD isolate, a pure form of cannabidiol. 

How Dogs With Arthritis Can Take CBD Oil 

Most CBD brands, such as Honest Paws and Holistapet, offer various dog products in different CBD extracts. These items include:

  • CBD tinctures
  • CBD dog treats
  • CBD topicals
  • CBD peanut butter
  • CBD soft chews
  • CBD capsules 
  • CBD pet oil  

CBD dog treats are orally ingested. However, if you want the most control in dosing, you may go for tinctures or oils instead. You can easily add tinctures and oils to your dog’s food or drink(45).  

You can also administer CBD tinctures and oil topically and sublingually (under your dog’s tongue). CBD topicals are available in salves and creams. 

Most CBD products may contain additives like carrier oils that contribute to its possible therapeutic effects. MCT oil and coconut oil are common carriers(46)

Remember that CBD oil is different from hempseed oil. Hempseed oil does not contain cannabinoids. Still, it is rich in nutrients and fatty acids(47)

CBD Dosage for Dogs With Arthritis

A 2018 study from the Frontiers in Veterinary Science examined the safety and pain-relieving effect of cannabidiol in dogs with osteoarthritis (joint pain).  

Researchers hypothesized that if dogs with osteoarthritis take 2mg of CBD per kilogram of body weight twice a day, they may have increased activity and comfort(48).  

However, the Food and Drug Administration or FDA in the USA has not approved cannabidiol as a medical treatment(49). Hence, there is no available dosage of CBD for dogs with arthritis. 

The only cannabis-derived medication recognized by the FDA is Epidiolex. It is used to manage seizures related to childhood epilepsy(50).

Epilepsy is occasionally seen in dogs. The seizures usually begin when the dog is still young, around two or three years old(51).  

However, you may start administering CBD oil to your dog at low doses and then slowly adjust the dosage until you see your desired results.  

Note that the amount of CBD your dog needs depends on its size. Generally, large dogs may require higher doses of CBD for the compound to take effect(52)

Legality of CBD 

Federal law may limit how veterinarians can discuss the use of CBD oil with dog owners. However, you should be comfortable initiating a discussion(53)

In Colorado, the local government expanded its state law on cannabis in 2012. The Centennial state legalized the adult use of recreational marijuana(54)

Adult Coloradans are also allowed to grow marijuana in their homes(55). However, it is not clear whether Colorado allows the use of CBD in dogs. 

On the other hand, licensed veterinarians in Nevada can recommend hemp and CBD products to their patients, provided that the THC level is not more than 0.3%(56)

If you are from South Dakota, the local government does not allow the possession of CBD products. Hemp and CBD oil are still illegal in Mount Rushmore state(57). Therefore, owning CBD pet products is deemed a violation of state law.  

Product Frequently
Asked Questions

  • How can CBD help with dogs with arthritis?

    A study from the Frontiers in Veterinary Science published in 2018 suggested that 2 mg of CBD administered twice daily may help increase comfort and activity in dogs with osteoarthritis(58).  

    Osteoarthritis is a common form of arthritis. Large breeds or older dogs usually experience this condition(59)

    OA is a progressively worsening joint inflammation triggered by the deterioration of cartilage(60)Based on an animal study, CBD’s combined anti-inflammatory and immunosuppressive actions may have an anti-arthritic effect in murine collagen-induced arthritis(61).

    Although the result is promising, the study is not specific to dogs with arthritis. Therefore, more studies are needed to determine CBD’s therapeutic effects on arthritic canines.

  • What evidence or research exists to say that CBD helps with dogs with arthritis?

    The studies about CBD’s health benefits on dogs with arthritis symptoms are limited. Nonetheless, there has been a growing interest in cannabidiol’s anti-inflammatory properties that may benefit dogs(62)

    A study from Veterinary Sciences published in 2021 examined the immuno-modulating and anti-inflammatory properties of CBD for the first time directly on canines.

    The results showed that CBD may reduce dogs’ inflammatory response. However, the researchers encourage more studies to understand the possible therapeutic role of cannabidiol in veterinary medicine(63)

    An animal study posted in the European Journal of Pain indicated that transdermal CBD application may attenuate arthritis pain-related behaviors and inflammation without detrimental side effects(64).  A transdermal route is a form of substance administration delivered through the skin(65).

  • Is there any evidence that CBD can make dogs with arthritis worse?

    No. There have been no direct studies on how CBD can worsen arthritic dogs’ conditions

  • Will CBD interact with any current medication given for dogs with arthritis?

    Researchers hypothesized that it may not be wise to give CBD concomitantly with other medications due to possible drug-to-drug interactions(66)

    Make sure to keep your veterinarian informed about your plan to administer CBD oil to your arthritic dog. 

    Under the current federal law, veterinarians are still not allowed to prescribe CBD to their patients. However, you can initiate a discussion about it with them(67).  

  • Are there other treatments I should consider alongside CBD to help dogs with arthritis?

    Prescription drugs for arthritic dogs include opioids and nonsteroidal anti-inflammatory drugs or NSAIDs. However, these substances raise safety concerns, especially for aging dogs(68)

    Therefore, as a pet parent, you must consult your veterinarian if you consider other treatments for your arthritic dog.

  • What is the dosage for dogs with arthritis?

    According to researchers, dogs with osteoarthritis may take 2mg of CBD per kilogram of body weight twice a day(69)

    However, the study is inconclusive, and the FDA has not approved cannabidiol as a medical treatment. 

    Therefore, there is no standard CBD dosage for dogs with arthritis.

  • Is CBD oil safe for dogs with arthritis?

    There have been limited studies examining CBD oil’s safety when used by arthritic dogs. However, CBD is generally safe to use(70)

    A 2019 research published in the Animals journal stated that the use of cannabidiol-rich hemp products is becoming popular among pet ownersFurthermore, the study showed that CBD use appeared to be safe in healthy adult dogs(71)

  • What are the benefits of CBD oil for dogs with arthritis?

    CBD oil may help with pain caused by arthritis. Research showed that cannabidiol may help increase the comfort and activity of dogs with osteoarthritis (72).

  • What happens if I give my dog an excessive amount of CBD?

    The American Kennel Club stated that since there have been no formal studies on how CBD affects dogs, they do not know what dosage would be toxic. 

    Any form of medication may carry a risk of reaction. Therefore, if you want to administer CBD to your arthritic dog, you should begin with a low CBD dosage and slowly increase it until you see the desired result(73).

    Most importantly, make sure to speak with your veterinarian. They may check your dog’s body weight and perform other physical tests to determine proper care for your dog with arthritis.

 


    1. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    2. Osteoarthritis in Dogs
      https://www.acvs.org/small-animal/osteoarthritis-in-dogs
    3. CBD Oil for Dogs: What You Need to Know
      https://www.akc.org/expert-advice/health/cbd-oil-dogs/
    4. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
      https://pubmed.ncbi.nlm.nih.gov/10920191/
    5. Immune Responses Regulated by Cannabidiol
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/
    6. The Endocannabinoid System of Animals
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770351/
    7. Homeostasis: The Underappreciated and Far Too Often Ignored Central Organizing Principle of Physiology
      https://www.frontiersin.org/articles/10.3389/fphys.2020.00200/full
    8. The Endocannabinoid System, Our Universal Regulator
      https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
    9. Ibid.
    10. Ibid.
    11. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
      https://pubmed.ncbi.nlm.nih.gov/10920191/
    12. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    13. Ibid.
    14. Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats
      https://www.mdpi.com/2076-2615/9/10/832
    15. Oral Transmucosal Cannabidiol Oil Formulation as Part of a Multimodal Analgesic Regimen: Effects on Pain Relief and Quality of Life Improvement in Dogs Affected by Spontaneous Osteoarthritis
      https://www.mdpi.com/2076-2615/10/9/1505
    16. The Canine Brief Pain Inventory
      http://www.vet.upenn.edu/docs/default-source/VCIC/canine-bpi-user%27s-guide-2017-07
    17. Osteoarthritis in Dogs — Signs and Treatment
      https://www.akc.org/expert-advice/health/osteoarthritis-signs-treatment/
    18. CBD Oil for Dogs: What You Need to Know
      https://www.akc.org/expert-advice/health/cbd-oil-dogs/
    19. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
      https://www.mdpi.com/2306-7381/8/9/185
    20. Function and biogenesis of lipopolysaccharides
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091223/
    21. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
      https://www.mdpi.com/2306-7381/8/9/185
    22. Ibid.
    23. Osteoarthritis in Dogs — Signs and Treatment
      https://www.akc.org/expert-advice/health/osteoarthritis-signs-treatment/
    24. Ibid.
    25. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
      https://www.mdpi.com/2306-7381/8/9/185
    26. Osteoarthritis in Dogs — Signs and Treatment
      https://www.akc.org/expert-advice/health/osteoarthritis-signs-treatment/
    27. Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs
      https://avmajournals.avma.org/doi/full/10.2460/ajvr.82.5.405
    28. How to Talk to Your Veterinarian About CBD Oil for Dogs
      https://www.akc.org/expert-advice/health/talk-veterinarian-cbd-oil/
    29. Nevada veterinarians can treat patients with certain cannabis products
      https://www.avma.org/javma-news/2021-10-01/nevada-veterinarians-can-treat-patients-certain-cannabis-products
    30. CBD: A Patient’s Guide to Medicinal Cannabis
      https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
    31. Is CBD safe for dogs? Guidelines from vets about giving your dog CBD
      https://www.insider.com/cbd-for-dogs
    32. CBD: A Patient’s Guide to Medicinal Cannabis
      https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
    33. Is CBD safe for dogs? Guidelines from vets about giving your dog CBD
      https://www.insider.com/cbd-for-dogs
    34. Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038832/#b14-cjvr_07_178
    35. Drug Bioavailability
      https://www.ncbi.nlm.nih.gov/books/NBK557852/
    36. Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038832/#b14-cjvr_07_178
    37. Half-Life
      https://www.ncbi.nlm.nih.gov/books/NBK554498/
    38. CBD Oil for Dogs: What You Need to Know
      https://www.akc.org/expert-advice/health/cbd-oil-dogs/
    39. How to Talk to Your Veterinarian About CBD Oil for Dogs
      https://www.akc.org/expert-advice/health/talk-veterinarian-cbd-oil/
    40. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
      https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
    41. Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing
      https://www.jstage.jst.go.jp/article/jts/40/6/40_797/_pdf/-char/en
    42. CBD: A Patient’s Guide to Medicinal Cannabis
      https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
    43. How to Choose CBD For Dogs?
      https://www.akc.org/expert-advice/health/does-cbd-work-for-dogs/
    44. Ibid.
    45. Healing with CBD
      https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
    46. Ibid.
    47. Hemp Seed Oil Properties
      https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
    48. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    49. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
      https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
    50. Epidiolex (cannabidiol) oral solution
      https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210365lbl.pdf
    51. CBD: A Patient’s Guide to Medicinal Cannabis
      https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
    52. Is CBD safe for dogs? Guidelines from vets about giving your dog CBD
      https://www.insider.com/cbd-for-dogs
    53. How to Talk to Your Veterinarian About CBD Oil for Dogs
      https://www.akc.org/expert-advice/health/talk-veterinarian-cbd-oil/
    54. Legal marijuana use in Colorado
      https://cannabis.colorado.gov/legal-marijuana-use-in-colorado
    55. Home grow laws
      https://cannabis.colorado.gov/legal-marijuana-use/home-grow-laws
    56. Nevada veterinarians can treat patients with certain cannabis products
      https://www.avma.org/javma-news/2021-10-01/nevada-veterinarians-can-treat-patients-certain-cannabis-products
    57. ATTORNEY GENERAL RAVNSBORG CLARIFIES QUESTIONS REGARDING INDUSTRIAL HEMP AND CBD (Cannabidiol) OIL
      https://atg.sd.gov/OurOffice/Media/pressreleasesdetail.aspx?id=2167
    58. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    59. Osteoarthritis in Dogs
      https://www.acvs.org/small-animal/osteoarthritis-in-dogs
    60. Osteoarthritis in Dogs — Signs and Treatment
      https://www.akc.org/expert-advice/health/osteoarthritis-signs-treatment/
    61. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
      https://pubmed.ncbi.nlm.nih.gov/10920191/
    62. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473042/
    63. Ibid.
    64. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/
    65. Transdermal drug delivery
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
    66. The Impact of Feeding Cannabidiol (CBD) Containing Treats on Canine Response to a Noise-Induced Fear Response Test
      https://www.frontiersin.org/articles/10.3389/fvets.2020.569565/full
    67. How to Talk to Your Veterinarian About CBD Oil for Dogs
      https://www.akc.org/expert-advice/health/talk-veterinarian-cbd-oil/
    68. Systematic review of nonsteroidal anti-inflammatory drug-induced adverse effects in dogs
      https://pubmed.ncbi.nlm.nih.gov/23782347/
    69. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    70. Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826847/
    71. Ibid.
    72. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065210/
    73. CBD Oil for Dogs: What You Need to Know
      https://www.akc.org/expert-advice/health/cbd-oil-dogs/

What’s new

Why Trust CBD Clinicals?

    Our Medical Team

    The following medical professionals are part of the CBD Clinicals’ medical review team. We focus on ensuring our content is accurate, evidence-based, current and trustworthy.

    Read more

    Our Editorial Process

    The CBD Clinicals Team is committed to producing CBD-related content that is current, factual, unbiased, evidence-based, and medically reviewed.

    Read more

    Our Ethical Principles

    We are committed to helping individual consumers realize the full benefits of CBD to improve their health and that of their families (including their dogs, cats & other pets).

    Read more

Our mission at CBD Clinicals is to provide the most applicable, medically reviewed CBD content on the web.

Ezoicreport this ad