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Best CBD Oil for Thyroid Health

Weight issues, anxiety, and sleep problems are common symptoms of thyroid disease. If you are experiencing these symptoms and want to try CBD to achieve better thyroid health, CBD Clinicals has all the information you need regarding CBD for improved wellbeing.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Compare the Best CBD Oil for Thyroid Health in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5

Best CBD Oil for Thyroid Health

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How CBD May Help With the Thyroid

The endocrine system refers to a series of glands in the body that creates hormones, which help cells communicate with each other. 

When these glands fail to produce the right amount of hormones that the body needs, diseases may develop and affect many aspects of life(1).  

One of the main glands that produce hormones is the thyroid gland. It is a butterfly-shaped gland in front of the neck and is responsible for how the body uses energy(2)

A 2018 study mentioned that there have been interrelations between the activity of the endocrine system and the ECS (endocannabinoid system)(3)

Found in mammals, the ECS is a system responsible for maintaining bodily balance or homeostasis. The cannabinoid receptors, namely CB1 and CB2, enable the ECS to regulate various functions in the body, including thyroid functions

Research from the European Journal of Endocrinology identified CB1 receptors on the thyroid gland of rat models. These receptors modulate the hormone production of two types of thyroid hormones, T3 (triiodothyronine) and T4 (thyroxine)(4)

Thyroid hormones regulate the rate at which calories are burned, affecting weight gain or weight loss. These hormones can also speed up or slow down the heart rate(5).

A study from BioMed Research International stated that thyroid glands have significant concentrations of CB1 and CB2 receptors(6)

These cannabinoid receptors have been associated with the diminution of thyroid tumors, showing promise as prospective blockers of the spread of malignant cells on the glands(7)

Cannabidiol, popularly known as CBD, is a cannabinoid present in the cannabis plant. 

Although this non-psychoactive compound has low-affinity binding for CB1 and CB2 receptors, CBD may antagonize them in the presence of THC (tetrahydrocannabinol)(8)

It is unclear how CBD’s interaction with the cannabinoid receptors may affect thyroid conditions. Still, CBD is thought to have potential health benefits, such as analgesic and anti-inflammatory properties, without the psychoactive effects of THC(9)

These characteristics make CBD a promising therapy for various medical conditions, including thyroid diseases

For instance, hypothyroidism or underactive thyroid is a condition where the thyroid does not create sufficient thyroid hormones into one’s bloodstream, leading to a slower metabolism.

Individuals with an underactive thyroid may consult their healthcare provider if they want to use CBD oil and other CBD-derived products to manage their symptoms.

Hair loss is a symptom of hypothyroidism(10). In a study involving patients with alopecia, the subjects reported a 93.5% increase in hair regrowth following six months of CBD-rich hemp extract administration(11)

Meanwhile, swelling in the neck from goiter or enlarged thyroid gland, difficulty sleeping, anxiety, and irritability are symptoms of an overactive thyroid(12)

Aside from having anti-inflammatory properties, CBD may also help with sleep and anxiety-related disorders(13-14)

Although these potential health benefits seem promising for managing various thyroid conditions like an underactive thyroid, a direct study examining how CBD may help with thyroid is warranted. 

Benefits of Using CBD for Thyroid

The ATA (American Thyroid Association) said that individuals with thyroid disease choose complementary and alternative medicine to avoid dealing with the side effects of thyroid medications, such as dry mouth, weight gain, fatigue, and mental fogginess(15).  

CBD, for instance, is an alternative medicine with a good safety profile(16). It also has pain-relieving effects(17).    

Some people with hypothyroidism may experience joint pain and muscle problems like tenderness and overall muscle weakness(18). People with such a condition may also have a higher risk of developing autoimmune diseases, like rheumatoid arthritis. 

A 2020 research article from Nature suggested that CBD may help with inflammatory rheumatoid arthritis(19)

Hypothyroidism commonly causes dry skin. The dryness of hypothyroid skin results from sweat gland changes(20)

A 2020 study from Clinical, Cosmetic and Investigational Dermatology suggested that the topical application of CBD may help with skin disorders such as eczema, which has symptoms that include dry skin(21)

Meanwhile, Graves’ disease is a form of autoimmune disorder that may trigger overactive thyroid. The condition is more common among women and individuals over 30(22).   

People are more likely to develop Graves’ disease when they have other autoimmune disorders, such as type 1 diabetes(23). This condition occurs when one’s blood sugar is too high.

In a randomized controlled trial, CBD was shown to lower incidences of diabetes in non-obese diabetic mice, an animal model of spontaneous type 1 diabetes development(24).  

These studies may look promising. However, some of them were conducted on animals. Still, researchers who want to explore the benefits of CBD for the thyroid may find these findings useful. 

Longitudinal research is warranted to determine how CBD oil helps individuals with thyroid issues.  

How to Take CBD Oil for Thyroid Disorders

There are several ways to take CBD to manage symptoms associated with thyroid disorders. Here are the common routes of administration to benefit from the effects of CBD:

  • Inhalation
  • Ingestion
  • Topical administration
  • Sublingual (under the tongue) route
  • Transdermal administration (active ingredients delivered across the skin for systematic distribution)

The fastest way to benefit from CBD is by inhaling the compound using vape pens(25). When inhaled, CBD may take effect between two to 15 minutes(26).

However, an article from Harvard Health Publishing stated that vaping may cause lung disorders(27). Hence, smoking CBD may not be an option for others. 

If you want to try this administration route to benefit from the effects of CBD, it is best to consult your doctor. 

Meanwhile, if you opt for the ingestion route, CBD gummies may be a good option, especially if you do not like the natural grassy taste of CBD oil (hemp oil). 

Tinctures, which are alcohol-based, are generally taken sublingually. However, CBD oils can also be ingested(28)

You may add CBD oil to your food or beverages. Researchers from the University of Minnesota hypothesized that high-fat foods may increase oral CBD absorption into the body(29).

CBD Dosage

The FDA (Food and Drug Administration) does not recognize CBD as thyroid medication. Therefore, there is no standard CBD dosage for certain thyroid conditions

In a 2017 study, researchers suggested that chronic CBD use and high doses of up to 1,500mg daily may be well tolerated in humans(30)

In addition, doses between 10mg and 100mg of CBD daily may help with pain, inflammation, and autoimmune disorders(31)

Autoimmune disorders refer to problems with the body’s immune system response. Such conditions usually cause inflammation(32)

Hashimoto’s thyroiditis is a common autoimmune disorder(33). It refers to the inflammation of the thyroid gland and is the most prevalent cause of hypothyroidism in the U.S(34).   

The doses previously mentioned may be effective for some people. Still, it is suggested that patients work with a healthcare professional experienced in recommending cannabidiol for the appropriate dosage and delivery method. 

How Long Does CBD Take to Help With Thyroid Conditions?

How long CBD takes to help with thyroid issues depends on the route of administration and several other factors like CBD potency, the severity of one’s condition, and individual body weight

CBD’s onset via the ingestion route is between 30 to 90 minutes(35). Remember that your liver will process anything that goes into your stomach(36).

For instance, when taking CBD orally, your liver performs a first-pass metabolism on the compound before it enters your bloodstream(37). Hence, the onset of action is much longer than other delivery methods. 

Meanwhile, an International Journal of Pharmacy and Pharmaceutical Sciences review stated that peak blood vessels of most substances taken under the tongue are achieved in 10 to 15 minutes(38).   

However, CBD, in particular, has a 15 to 30-minute onset and a four to six-hour duration via the sublingual route(39).

How Long Will CBD Help With Thyroid Conditions?

How long CBD’s effects will last after the compound starts to help depends on its bioavailability and half-life.

The sublingual route relies on the mucous membrane under the tongue to absorb cannabidiol. The capillaries in the connective tissues diffuse the compound, which then enters the bloodstream(40)

The sublingual method avoids the stomach and liver. Hence, CBD’s bioavailability is between 6% and 20%(41)

Bioavailability refers to the amount of a substance that reaches circulation in the body and can provide an active effect. 

Meanwhile, the bioavailability of CBD via the ingestion route is between 6% and 15%(42)

A 2018 systematic review from Frontiers in Pharmacology mentioned that the half-life of CBD was reported between 1.4 and 10.9 hours after oromucosal spray use and two to five days after chronic oral administration(43).  

Half-life means the time needed for the concentration of a specific substance to decrease by 50% of its starting dose in the body.

It is believed that 94% to 97% of a substance will have been eliminated following four to five half-lives(44)

How to Choose the Right CBD for Thyroid Health

Choosing the best CBD oil for your thyroid health from various CBD products in the market can be challenging. 

Below are some essential factors to consider to help you choose a high-quality CBD oil product:

1. Make sure that the CBD online stores or dispensaries you choose are authorized to manufacture, distribute, and sell CBD products, like CBD oil

If possible, look for any disclaimers usually found on company websites or read customer feedback to get more insights into the brand. 

2. Verify if the CBD brand you choose has enlisted the services of a third-party laboratory to test all its products.

The lab report and COA (certificate of analysis) must be easily accessible. This way, consumers like you can check the accuracy of the advertised CBD potency and whether the products contain residual solvents. 

3. Find a CBD brand that uses all-natural, non-GMO hemp. Reputable CBD companies produce hemp plants or purchase from other manufacturers that practice sustainable farming. 

4. Familiarize yourself with the different CBD extracts and extraction methods used. 

Full-spectrum CBD oil products contain all compounds of the cannabis plant. It also has less than 0.3% THC concentration. This CBD variant is known to produce the entourage effect due to the presence of all cannabis compounds.

The entourage effect refers to the phenomenon when biologically active compounds of cannabis work better when administered together. 

Meanwhile, broad-spectrum CBD is similar to the full-spectrum variant. It also contains all the natural compounds of cannabis except for THC

Lastly, CBD isolate is a type of CBD that only contains pure cannabidiol. It undergoes an extraction and refinement process that removes all cannabis compounds, leaving CBD in its purest form.   

As for cannabis extraction, some standard methods include ethanol, solvent, and carbon dioxide (CO2) extraction techniques(45).  

In carbon dioxide extraction, compressed CO2 is used as the extraction solvent instead of flammable and toxic chemical solvents(46)

The Potential Side Effects and Risks of Using CBD for Thyroid

According to the WHO (World Health Organization), CBD is relatively safe and well tolerated in humans and animals(47). Still, CBD may induce risks and minor side effects, such as(48)

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue 

If you have thyroid disease, your healthcare provider aims to normalize your thyroid hormone levels(49)

For a patient with hyperthyroidism or a high level of thyroid hormones, treatment options may include beta-blockers, which help control symptoms(50)

However, beta-blockers use the cytochrome P450 enzyme system and may interact with CBD(51). The cytochrome P450 is a family of liver enzymes that metabolize around 60% of the pharmaceutical drugs people consume. 

At high doses, CBD may inhibit the activity of these enzymes, increasing the effect or duration of prescription drugs metabolized by cytochrome P450(52)

Another cause for concern is the labeling inaccuracy of most CBD products sold online. 

A study from the Journal of the Americal Medical Association examined 84 products from 31 companies(53). Of the tested products, about 26% contained less CBD than labeled, possibly negating any potential clinical response. 

Legality of CBD

The U.S. Congress ratified the 2018 Farm Bill, legalizing the commercial use of industrial hemp and products obtained from hemp plants(54)

The Farm Bill states that Cannabis sativa L. and other derivatives of cannabis with less than 0.3% of THC content on a dry weight basis are deemed legal under federal law(55)

Some states like Colorado have passed laws permitting recreational and medical marijuana use. Still, these state laws do not alter the fact that marijuana is still listed as a Schedule I drug under federal law(56-57)

Substances listed as Schedule I drugs have a high abuse potential with no accepted medical use. For this reason, medications under this category may not be administered, prescribed, or dispensed under federal law. 

However, the U.S. Attorney General, who works with the Secretary of the Department of Health and Human Services to determine a medication’s Schedule, has the authority to remove, add, or switch medications from one Schedule to another(58)

Since rules and regulations regarding medical cannabis are confusing, consumers should learn more about the various state laws to avoid possible legal repercussions. 

Product Frequently
Asked Questions

  • How can CBD help with thyroid problems?

    There is no direct study examining how CBD can help with the thyroid, a gland that regulates body temperature and controls heart rate and metabolism. 

    However, the non-psychoactive compound has potential anti-anxiety effects and anti-inflammatory properties(59-60). These purported health benefits may help with symptoms associated with a particular thyroid disease

    For instance, swelling in the neck from goiter, difficulty sleeping, anxiety, and irritability are symptoms of an overactive thyroid(61)

  • What evidence or research exists to say that CBD helps with thyroid issues?

    Some people with hypothyroidism may experience joint pain and muscle aches(62). CBD is known for its pain-relieving effects(63). Hence, CBD may help with pain management.

  • Is there any evidence that CBD can make thyroid diseases worse?

    No evidence suggests that CBD can make thyroid diseases worse. 

    However, a 2017 study indicated that cannabis-based products were not associated with thyroid dysfunction. Still, cannabis use was linked to significantly low levels of thyroid-stimulating hormones(64).

  • Will CBD interact with any current medication I may be taking for my thyroid?

    Some people with hypothyroidism take levothyroxine, a thyroid hormone used with surgery and radioactive iodine therapy, to treat thyroid cancer(65).  

    Radioactive iodine therapy is used for the treatment of overactive thyroid and certain types of thyroid cancer. It is a safe and reliable treatment that targets thyroid cells(66). 

    Still, the best therapy for thyroid depends on your doctor’s recommendation. Always consult your healthcare provider for medication or therapy options to help with your thyroid issues. 

    Levothyroxine has a broad drug-to-drug interaction spectrum, including inhibitions of cytochrome P450(67). Cytochrome P450 is a family of liver enzymes. At high doses, CBD may also inhibit these enzymes(68)

    Hence, taking CBD with levothyroxine simultaneously may cause drug interactions. 

  • Are there other treatments I should consider alongside CBD to help with thyroid issues?

    For overactive thyroid, your healthcare provider may prescribe radioactive iodine and anti-thyroid medications to reduce the production of thyroid hormones(69)

    However, make sure to talk with your healthcare provider if you consider using CBD alongside other treatments to help with specific thyroid issues. This way, they can advise you regarding possible risks and adverse reactions.

  • Can I fail a drug test if I use CBD for my thyroid?

    No. CBD is non-psychoactive. Hence, it will not cause a euphoric effect. However, some CBD products contain traces of THC that may build up in the body when taken regularly in a span of four to six days(70).

    An increased THC level in the bloodstream may result in a positive drug test.  

  • What is the dosage for thyroid diseases?

    There is no standard CBD dosage for thyroid diseases. However, doses between 10mg and 100mg of CBD daily may help with pain, inflammation, and autoimmune disorders(71).

    Hashimoto’s thyroiditis is an autoimmune disorder(72). It is an inflammation of the thyroid glands(73)

    Hence, individuals with such a condition may find the suggested dosage helpful. Still, it is best to talk with a healthcare professional experienced in cannabis use, especially if you will be using CBD for the first time. 

    This way, they can recommend an appropriate dosage for your specific thyroid problem.  

  • How is thyroid disease diagnosed?

    Thyroid disease is diagnosed through blood tests. The specific blood test used is the TSH (thyroid-stimulating hormone). TSH is the first test your healthcare provider will do to check for thyroid hormone imbalance(74).


  1. Your Health and Hormones
    https://www.endocrine.org/patient-engagement
  2. Endocrine System
    https://my.clevelandclinic.org/health/articles/21201-endocrine-system
  3. The Effects of Cannabinoids on the Endocrine System
    https://pubmed.ncbi.nlm.nih.gov/30618031/
  4. Evidence for Functional CB1 Cannabinoid Receptor Expressed in the Rat Thyroid
    https://pubmed.ncbi.nlm.nih.gov/12153749/
  5. Thyroid Hormone Production and Function
    https://www.uofmhealth.org/health-library/ug1836#:~:text=Thyroid%20hormones%20affect%20every%20cell,or%20speed%20up%20the%20heartbeat.
  6. Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619873/
  7. Ibid.
  8. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  9. Ibid.
  10. Thyroid Disease
    https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease
  11. Hair Regrowth With Cannabidiol (CBD)-Rich Hemp Extract –A Case Series 
https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
  12. Overactive Thyroid (Hyperthyroidism)
    https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/
  13. Antioxidative and Anti Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  14. Cannabidiol in Anxiety and Sleep: A Large Case Series
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/
  15. Complementary and Alternative Medicine in Thyroid Disease (CAM)
    https://www.thyroid.org/thyroid-disease-cam/
  16. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  17. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  18. Hypothyroidism: Does It Cause Joint Pain?
    https://www.mayoclinic.org/diseases-conditions/hypothyroidism/expert-answers/hypothyroidism/faq-20057789
  19. Cannabidiol (CBD): A Killer for Inflammatory Rheumatoid Arthritis Synovial Fibroblasts
    https://www.nature.com/articles/s41419-020-02892-1
  20. Thyroid Hormone Action on Skin
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219173/
  21. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  22. Graves’ Disease
    https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease#:~:text=Graves’%20disease%20is%20an%20autoimmune,the%20way%20your%20heart%20beats.
  23. Ibid.
  24. Experimental Cannabidiol Treatment Reduces Early Pancreatic Inflammation in Type 1 Diabetes
    https://pubmed.ncbi.nlm.nih.gov/27767974/#:~:text=Cannabidiol%20(CBD)%2C%20a%20phytocannabinoid,model%20of%20spontaneous%20T1D%20development.
  25. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  26. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  27. Can Vaping Damage Your Lungs? What We Do (and Don’t) Know
    https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  28. Healing With CBD, page 205.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  29. High-Fat Foods Can Increase Oral Cannabidiol Absorption Into the Body
    https://www.sciencedaily.com/releases/2019/08/190813130426.htm
  30. Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  31. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  32. CBD: A Patient’s Guide to Medicinal Cannabis, page 204.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  33. Ibid
  34. Hashimoto’s Thyroiditis (Lymphocytic Thyroiditis)
    https://www.thyroid.org/hashimotos-thyroiditis/#:~:text=Hashimoto’s%20thyroiditis%2C%20also%20known%20as,tends%20to%20run%20in%20families.
  35. Healing With CBD, page 191.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  36. Healing With CBD, page 202.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  37. Ibid.
  38. Sublingual Mucosa as a Route for Systemic Drug Delivery
    https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1092.pdf
  39. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  40. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  41. Ibid.
  42. Healing With CBD, page 191.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  43. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  44. Half-Life
    https://www.ncbi.nlm.nih.gov/books/NBK554498/
  45. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  46. Ibid.
  47. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  48. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700#:~:text=Though%20it’s%20often%20well%2Dtolerated,dosage%20of%20CBD%20in%20products.
  49. Thyroid Disease
    https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease
  50. Ibid.
  51. Healing With CBD, pages 114-116
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  52. Ibid.
  53. Labeling Accuracy of Cannabidiol Extracts Sold Online
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818782/
  54. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  55. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  56. HOUSE BILL 21-1317
    https://leg.colorado.gov/sites/default/files/2021a_1317_signed.pdf
  57. The Federal Controlled Substances Act: Schedules and Pharmacy Registration
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839489/#:~:text=The%20Federal%20Comprehensive%20Drug%20Abuse,effective%20on%20May%201%2C%201971.&text=The%20goal%20of%20the%20Controlled,and%20dispensing%20of%20controlled%20substances.
  58. Ibid.
  59. Cannabidiol as a Potential Treatment for Anxiety Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/#:~:text=We%20found%20that%20existing%20preclinical,have%20investigated%20chronic%20CBD%20dosing.
  60. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#:~:text=Therefore%2C%20it%20has%20been%20suggested,of%20immune%20cells%20%5B66%5D.
  61. Overactive Thyroid (Hyperthyroidism)
    https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/
  62. Hypothyroidism: Does It Cause Joint Pain?
    https://www.mayoclinic.org/diseases-conditions/hypothyroidism/expert-answers/hypothyroidism/faq-20057789
  63. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  64. Effect of Marijuana Use on Thyroid Function and Autoimmunity
    https://pubmed.ncbi.nlm.nih.gov/27799014/
  65. Levothyroxine
    https://medlineplus.gov/druginfo/meds/a682461.html
  66. Radioiodine (Radioactive Iodine) Therapy
    https://my.clevelandclinic.org/health/treatments/16477-radioiodine-radioactive-iodine-therapy
  67. No Effect of Levothyroxine and Levothyroxine-Induced Subclinical Thyrotoxicosis on the Pharmacokinetics of Sorafenib in Healthy Male Subjects
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646750/#:~:text=Levothyroxine%20has%20a%20wide%20drug,tyrosine%20kinase%20inhibitors%20(15).
  68. Healing With CBD, page 114.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  69. Hyperthyroidism (overactive thyroid)
    https://www.mayoclinic.org/diseases-conditions/hyperthyroidism/symptoms-causes/syc-20373659
  70. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  71. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  72. CBD: A Patient’s Guide to Medicinal Cannabis, page 204.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  73. Hashimoto’s Thyroiditis (Lymphocytic Thyroiditis)
    https://www.thyroid.org/hashimotos-thyroiditis/#:~:text=Hashimoto’s%20thyroiditis%2C%20also%20known%20as,tends%20to%20run%20in%20families.
  74. Thyroid Disease
    https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease
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