Best CBD Oil for the Immune System
Are you searching for a natural remedy that may provide beneficial effects for your immune system? This article reviews the promising health benefits of CBD oils and how this product may help improve your body’s immunity.
Best CBD Oil for the Immune System 2024
- Spruce 750mg Lab Grade CBD Oil Editor's Pick
- NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil Best Organic
- Spruce 2400mg Lab Grade CBD Oil Editor's Pick
- Avida Full Spectrum CBD Oil Tincture 500mg Best Seller
- cbdMD CBD Oil Tincture Natural 1500mg Best Natural Alternative
- CBDistillery THC Free CBD Oil Tinctures Best THC-Free
- cbdMD CBD Oil Tincture Natural 750mg Best Customer Rated
- NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil Best Starter
- Hemp Bombs 750mg CBD Oil Best Flavor Range
Compare the Best CBD Oil for the Immune System in 2022
Best CBD Oil for the Immune System
1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Mid-strength |
No other flavors |
Natural peppermint flavor |
|
Made from 100% organic and natural ingredients |
Overview
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Pure CBD hemp |
No other flavors |
All natural |
|
Approximately 300 drops total |
Overview
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Extra Strength |
Tastes bitter |
No artificial flavoring or colors |
No THC-free option |
Made from 100% organic and natural ingredients |
Overview
The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.
4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Light Spearmint flavor |
No other flavor |
Non-THC, Non-detected in drug test |
Overview
Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.
5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Various delicious flavors to choose from |
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options |
Has vegan, organic, and gluten-free ingredients |
|
Free shipping for this particular product within USA |
|
World-class customer service team |
Overview
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
60-Day Satisfaction Guarantee |
Dropper is a bit shaky |
Various strengths |
|
Oil extracted from aerial plant parts of US grown industrial hemp |
|
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices |
Overview
CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.
7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Pure CBD hemp |
No other flavors |
All natural |
A bit pricey compared to competitors |
Approximately 100 drops total |
Overview
This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.
8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Vegan and Gluten free |
Does not ship internationally |
Has a third-party lab test |
|
Wide variety of CBD strengths and sizes |
Overview
A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.
9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Wide variety of flavors |
Incomplete information about the product |
Lab test results are complete |
Does not ship to all international countries |
30-day money-back guarantee |
Overview
Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.
How CBD Helps With the Immune System
Studies showed that cannabidiol (CBD) has anti-inflammatory, antioxidant, antipsychotic, antinausea, and anti-anxiety effects(1).
CBD engages the endocannabinoid system (ECS) of the body. The ECS contains receptors responsible for regulating various body functions involved with systems like the central nervous system, cardiovascular system, and immune system(2).
The immune system provides your body with protection against foreign entities like bacteria, toxins, viruses, and fungi(3). The immune system is a network of white blood cells, proteins, organs, and chemicals(4).
A 2020 study published in Cannabis and Cannabinoid Research stated that CBD has promising anti-inflammatory and immunosuppressive properties(5).
Immunosuppressants prevent the immune system from mistaking healthy cells and tissue for foreign entities like germs or bacteria. By holding back the immune system, immunosuppressants can help prevent inflammation and cell damage(6).
Benefits of Using CBD for the Immune System
Studies showed that the anti-inflammatory properties of cannabis may be beneficial under certain conditions because inflammation is considered a key event associated with various diseases(7).
For example, chronic inflammation has a significant role in a person’s decreased mental function associated with the human immunodeficiency virus (HIV).
CBD as an immunosuppressant may help prevent various autoimmune diseases and provide chronic pain relief. These diseases include inflammatory bowel disease, lupus, multiple sclerosis, psoriasis, and rheumatoid arthritis(8).
How Long Does CBD Take to Help the Immune System?
Different types of CBD products may have varying onset times. Here are facts about CBD products and their onset duration(9):
- CBD oil tinctures applied directly under the tongue may take about 15 minutes to an hour.
A sublingual application usually allows the dose of CBD to be absorbed immediately into the bloodstream rather than passing through the digestive system.
- CBD capsules and edibles are taken orally and pass through the digestive system and may take up to 60 minutes before the body absorbs them.
- Topicals are applied to the exterior part of the body, like the skin. CBD absorption depends on how much fat is stored under the skin and the amount of hair present on the skin’s surface.
- CBD inhalant products like vapes are absorbed through the lungs. These products usually take effect within minutes.
Many reports have associated vaping with lung disease(10). Caution needs to be taken before using CBD oil vapes. Individuals must consult a health professional before considering vaping as an option to take CBD.
CBD Dosage Guide
The Food and Drug Administration (FDA), to date, does not consider CBD an approved treatment method except for Epidiolex, a cannabis-based medication for epilepsy(11). To date, there is currently no generally accepted dosage for taking CBD.
Several studies have been conducted to determine accepted dosage schemes for different types of disorders. The lab test results varied because those studies employed considerable variations in dosage levels and methods of administration(12).
Since CBD has not been approved as medication, doctors cannot provide prescriptions involving CBD or cannabinoids. Thus, there are no recommended CBD doses, and existing guides are for informational purposes only.
To date, clinical data is insufficient to determine a standard CBD dosage that may help benefit the immune system. However, there have been suggestions that taking small doses may be effective, especially for beginners(13).
CBD Usage Guide
CBD oil products come in different types and, thus, may be taken through various methods, such as the following(14):
- CBD oil tinctures are taken sublingually or under the tongue using a dropper. CBD is often blended with a carrier oil, like coconut or hemp seed oil. Some oil drops are flavored, like citrus or mint chocolate.
- Edibles are administered orally, and CBD effects ingested through this method may last longer than other product types. Some examples include CBD gummies, cookies, and chewable candies.
- CBD capsules are another orally administered product. Capsules usually contain medium-chain triglycerides or MCT oil to provide additional volume.
Additionally, softgel capsules may use olive oil as an ingredient for the casing.
- Topicals are applied externally to the body, usually on the affected area, such as the skin. Examples include lotions and creams. CBD is absorbed through the skin and bypasses liver metabolism.
- Vapes are smoked and inhaled and considered the fastest method to deliver CBD into the body. CBD oil can be unflavored or added with natural ingredients and flavoring to suit a person’s preferences.
Smoking or vaping has adverse health effects associated with lung disease(15). Professional opinion from a physician or health worker is recommended before using CBD vapes.
How Long Will CBD Help With the Immune System?
The duration of a CBD product’s effectiveness may vary depending on the product type, ingestion method, and dosage size.
Edibles and capsules have slow onset times. However, they may maintain their effectiveness for about 6 to 12 hours. Tinctures have an estimated duration of six to eight hours(16).
The effects of topicals like lotions and creams may last for five hours or more, while transdermal patches, which have long onsets, may last for a day or two.
Vapes commonly have fast onset times. However, their effects usually last for only two to three hours.
Risks and Side Effects of Using CBD for the Immune System
Despite various studies suggesting CBD’s promising benefits, research on CBD’s safety and efficacy is still ongoing.
Additionally, CBD still has side effects, although most of these effects are well-tolerated(17), even at high doses of around 1,500 mg of CBD per day(18).
These side effects include diarrhea, drowsiness, fatigue, loss of appetite, and dry mouth.
CBD may also react with certain medicines, such as blood thinners. These medications are broken down in the body by liver enzymes. Taking CBD together with these medications may cause the drugs to compete for these enzymes(19).
CBD products may come with a grapefruit warning. This warning means that the effects of CBD may block certain enzymes from breaking down other medications, increasing the drugs in the body that may cause other side effects(20).
Some studies suggested that CBD use may have adverse effects on the immune status of individuals(21). However, the findings are insufficient to support or refute this claim.
As stated by a 2017 report by the World Health Organization (WHO), CBD is not associated with any public health risks despite its side effects. These risks include comorbidities or driving under the influence(22).
In 2018, the FDA approved using CBD as a way to treat epilepsy(23). Other than that, the FDA has not approved the drug to help treat autoimmune diseases.
Ask for recommendations from a physician or health professional if you are considering CBD to help with wellness and manage health issues concerning the immune system.
Legality of CBD
The enactment of the 2018 Farm Bill took away hemp and hemp seeds from the Controlled Substances list of the Drug Enforcement Administration (DEA)(24).
The Farm Bill defines hemp as a Cannabis sativa plant containing no more than 0.3% of the delta 9-tetrahydrocannabinol (Δ9-THC), the psychoactive component that gives a high feeling.
This law allows the U.S. Department of Agriculture (USDA) to authorize and regulate hemp production. Under this law, hemp oil products are legal at the federal level. However, the regulation and legalization of hemp products will vary by state.
How to Choose the Best CBD Oil for the Immune System
CBD is a component of the Cannabis plant that does not have the same psychoactive properties as THC. Thus, CBD may be more appealing to use if you consider it for helping manage your immune system without altering your state of mind.
CBD is usually sourced from hemp plants because the plant only has trace amounts of THC content. Colorado is one of the U.S. states that supply most of the grown hemp required for CBD production(25).
There are several extraction methods to generate high-quality CBD from hemp. One of the most preferred methods is CO2 extraction, which uses high-pressure CO2 at fluctuating temperatures to extract CBD oil from the plant(26).
After extraction, CBD oil may be classified as full-spectrum, broad-spectrum, or CBD isolate.
Aside from CBD, full-spectrum CBD oil contains other cannabinoids and compounds like cannabichromene (CBC), cannabinol (CBN), cannabigerol (CBG), THC, and terpenes. These compounds are connected with various health benefits similar to that of CBD.
CBD users may prefer full-spectrum CBD oil because of the so-called “entourage effect.” Researchers believe that CBD provides more benefits when more cannabinoids and plant derivatives are present to attain maximal pharmacological effect(27).
Broad-spectrum CBD oil also has most cannabinoids present, like in full-spectrum hemp. However, it does not have THC content.
CBD isolates are products that contain pure CBD. Aside from being THC-free, isolates also do not contain cannabinoids other than CBD only.
Some CBD products originate from organic hemp extract and are turned into non-GMO or gluten-free products.
After CBD’s extraction and classification process, reputable brands that sell CBD products must send their product samples to a third-party lab for analysis.
The purpose of this analysis is to check for the amount of CBD concentrations and other ingredients.
Another purpose of third-party tests is to ensure that the products are safe and free of contaminants like pesticides, solvents, and heavy metals.
Many companies are selling CBD products these days. However, some of these CBD companies may be more trusted than others. Anecdotal online reviews suggested that these CBD oil brands are reputable and well-known:
- cbdMD – North Carolina
- CBDistillery – Colorado
- Joy Organics – Colorado
- Charlotte’s Web – Colorado
- MedTerra – California
Product Frequently
Asked Questions
-
How can CBD help with the immune system?
CBD may have immunosuppressant properties(28). The effects may help manage the immune system to prevent various autoimmune diseases and provide pain relief.
-
What evidence or research exists to say that CBD helps with the immune system?
A study published in Cannabis and Cannabinoid Research in 2020 mentioned that CBD has promising potential to provide anti-inflammatory and immunosuppressive effects(29).
-
Is there evidence that CBD can make the immune system worse?
There is insufficient evidence that CBD has any adverse effects on the immune system(30). However, CBD use may still have side effects, like drowsiness, diarrhea, and dry mouth(31).
-
Will CBD interact with any current supplements I may be taking for the immune system?
If you take other medications, CBD products may interact with those drugs and prevent those drugs from breaking down(32).
-
Are there other supplements I should consider alongside CBD to help with the immune system?
Consult a doctor or health professional regarding what supplements or medication you can take together with CBD to improve your well-being.
-
Can I fail a drug test if I use CBD for the immune system?
Drug tests do not test for CBD since CBD is not on the DEA’s list of controlled substances(33).
Some CBD products contain THC, which is a controlled substance. As long as THC levels are below the legal limit of 0.3%, you should pass the drug test.
-
What is the dosage for the immune system?
There are currently no generally accepted CBD doses for the immune system. Since the FDA has not approved CBD as medication, existing dosage guides are only informational.
-
How do you take CBD?
CBD tinctures are taken sublingually using a dropper, while edibles and capsules are ingested orally. Topicals are applied onto the skin, and vapes are taken by inhalation.
Vaping may cause lung damage. Thus, caution is advised when considering vaping as a method to take CBD.
-
Are there any side effects to CBD?
CBD does not contain any psychoactive effects associated with THC. However, CBD use may cause side effects like diarrhea, fatigue, and loss of appetite.
If you are under medication, like blood thinners, CBD may also interact with the medicines you are taking. Such interaction may cause additional side effects(34).
-
Is it legal to use CBD oil?
CBD use is legal within the U.S. at the federal level. Most U.S. states have authorized and regulated the production and selling of CBD products. However, the levels of restriction vary per state(35).
Check with your state’s laws to determine if your CBD product is legal. Additionally, review your product’s THC levels if they are below the legal limit of 0.3%.
- The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412000/ - Ibid.
- The immune system
https://www.hopkinsmedicine.org/health/conditions-and-diseases/the-immune-system - Immune system
https://my.clevelandclinic.org/health/articles/21196-immune-system - Immune Responses Regulated by Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/ - Immunosuppressants
https://my.clevelandclinic.org/health/drugs/10418-immunosuppressants - The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
https://www.ncbi.nlm.nih.gov/books/NBK425755/ - Immunosuppressants
https://my.clevelandclinic.org/health/drugs/10418-immunosuppressants - Best way to take CBD
https://www.projectcbd.org/guidance/best-way-take-cbd - Can vaping damage your lungs? What we do (and don’t) know
https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734 - FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy
https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms - Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092763/ - CBD dosing
https://www.projectcbd.org/guidance/cbd-dosing - Best way to take CBD
https://www.projectcbd.org/guidance/best-way-take-cbd - Can vaping damage your lungs? What we do (and don’t) know
https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734 - Best way to take CBD
https://www.projectcbd.org/guidance/best-way-take-cbd - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 - An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/ - Cannabidiol (CBD)-what we know and what we don’t
https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476 - Grapefruit Juice and Some Drugs Don’t Mix
https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix - The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
https://www.ncbi.nlm.nih.gov/books/NBK425755/ - Cannabidiol (CBD) pre-review report – agenda item 5.2
https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf - FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy
https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms - Hemp
https://www.usda.gov/topics/hemp - Hope for hemp: New opportunities and challenges for an old crop
https://www.ers.usda.gov/amber-waves/2020/june/hope-for-hemp-new-opportunities-and-challenges-for-an-old-crop/ - CBD oil: An introduction
https://www.projectcbd.org/wellness/cbd-oil-introduction - The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324885/ - Immune Responses Regulated by Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/ - Ibid.
- The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
https://www.ncbi.nlm.nih.gov/books/NBK425755/ - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 - Grapefruit Juice and Some Drugs Don’t Mix
https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix - FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 - State Medical Marijuana Laws
https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx