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Best CBD Oil for HIV

While HIV has no cure, increasing access to effective HIV prevention, diagnosis, treatment, and care has made HIV infection manageable(1). CBD Clinicals gives you the information you need to determine how CBD may help improve the quality of life of individuals with HIV.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil


3.5 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the Best CBD Oil for HIV in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

1.0 out of 5

5.0 out of 5

Best CBD Oil for HIV

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score
3.5
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes  Shipping not specified on website
 More flavors to choose from  3rd party lab result is currently not available on website
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Pros
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes
 More flavors to choose from
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Cons
 Shipping not specified on website
 3rd party lab result is currently not available on website
Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With HIV

HIV (human immunodeficiency virus) attacks CD4 cells (T cells), which are white blood cells that play a crucial role in the immune system by fighting infections(2).

It is worth noting that most people with HIV do not have AIDS (acquired immunodeficiency syndrome). AIDS is a severe form of HIV infection and is only diagnosed when a person’s CD4 count becomes extremely low(3)

CBD (cannabidiol) is an active cannabinoid present in the cannabis plant. This non-psychoactive compound has shown promise as a pharmaceutical and therapeutic drug target of several scientific investigations(4)

CBD and THC (tetrahydrocannabinol), the principal psychoactive constituent of cannabis, has been shown to interact with the endocannabinoid system’s cannabinoid receptors (CB1 and CB2)(5)

The endocannabinoid system (ECS) is responsible for maintaining balance in the body. CB1 and CB2 are involved in numerous physiological processes.

CB2 receptors have been shown to modulate immune cell functions, likely affecting CBD-induced anti-inflammatory effects(6). The compound is also believed to have immunosuppressive mechanisms(7)

The major challenges of the modern HIV treatment period are persistent inflammation and immune activation(8). CBD’s therapeutic potential may help with these challenges.   

A study from the journal Cellular Immunology indicated that CBD may maintain its immunosuppressive activity under low-level stimulation through the induction of functional regulatory T cells(9)

Regulatory T cells, also known as Tregs, are a specialized subpopulation of T cells that suppresses immune responses, maintaining homeostasis or balance. 

Tregs may prevent autoimmunity(10), a form of immune response of a particular organism against its healthy cells. 

These findings are not focused on CBD and its effect on HIV. Still, CBD’s therapeutic potential and activity in the ECS may help future researchers conducting longitudinal studies about CBD and how it may help with HIV. 

Benefits of Using CBD for HIV

Chronic pain in HIV patients is multifactorial and may be influenced by HIV-induced peripheral neuropathy (nerve damage), drug-induced peripheral neuropathy, and chronic inflammation(11)

Meanwhile, an experimental pain study suggested that CBD pain relief may be driven by its pharmacological action and psychological placebo effects(12)

The placebo effect creates a stronger connection between the brain and the body and how they work together(13)

Meanwhile, a systematic review and meta-analysis hypothesized that CBD may help with chronic neuropathic pain (nerve pain) by looking at 11 randomized controlled trials involving 1,219 participants(14)

A study led by Ethan B. Russo, MD, a psychopharmacology researcher and neurologist, mentioned that CBD appears to act as an inhibitor of glutamate neurotoxicity and seems to display antioxidant activity greater than vitamins C and E(15)

CBD may reduce the toxic levels of glutamate-induced neurotoxicity by 40%(16). Glutamate neurotoxicity refers to increasing damage of cell components, leading to cell death. HIV, in particular, induces cell death in T cells(17)

A clinical trial from Annals of Internal Medicine examined the short-term effect of cannabinoids in patients with HIV-1 infection(18)

Sixty-seven patients with HIV-1 infection were randomly assigned to a 3.95% THC-marijuana cigarette, a 2.5mg dronabinol (a manufactured form of THC capsule), or a placebo capsule three times per day before meals. 

The results showed that inhaled and ingested cannabinoids may not seem unsafe in individuals with HIV infection based on protease inhibitor levels, HIV RNA levels, and CD4+ and CD8+ cell counts over a 21-day treatment(19).  

Protease inhibitors are meds that may interact with enzymes that cleave protein. Meanwhile, CD4 is known as helper T cells that assist other blood cells in producing an immune response. CD8 induces cell death. 

Another thing that adds to CBD’s appeal as a therapeutic drug is its purported ability to offset the psychiatric side effects of THC(20)

Still, more longitudinal research is needed to elucidate the benefits of using CBD for HIV symptoms.

How to Take CBD Oil for HIV

There are various ways to take CBD oil for HIV. Below are commonly used administration routes to benefit from CBD:

  • Inhalation
  • Ingestion
  • Sublingual (under the tongue) route
  • Topical absorption 

Remember that these delivery methods have their pros and cons. 

For instance, inhaling CBD using vape pens is the fastest delivery method(21)

The onset time of CBD via the inhalation route is between 2 and 15 minutes, and its effect usually lasts from 2 to 4 hours(22)

However, most e-cigarette users report that they experience a dry mouth and throat following vaping(23). Individuals with primary infections of HIV may develop common symptoms, such as sore throat and painful mouth sores(24)

Therefore, vaping may not be safe for some HIV patients. In addition, vaping may damage the lungs(25)

Meanwhile, taking CBD under the tongue may ensure prompt compound delivery into one’s system(26)

Unlike smoking, the sublingual route does not expose the lungs to heat. Hence, you can avoid dealing with a smoky taste, dry mouth, and throat irritation(27)

The capillaries under the tongue and within the mouth absorb CBD into the bloodstream before being swallowed(28)

 If you choose to take CBD sublingually, you will feel its effect within 15 to 30 minutes, and it may last from 2 to 4 hours(29)

CBD Dosage for HIV

The FDA (Food and Drug Administration) has not approved CBD as a medical treatment for HIV. Therefore, there is no standard CBD dosage for such a condition.

HIV infection can damage lymphoid and mucosa tissues, resulting in progressive immunodeficiency excess levels of pathogens (disease-causing organisms) and inflammation(30)

Mid-range doses of CBD between 10mg and 100mg per day may help with inflammation, pain, weight loss, and several medical conditions, such as autoimmune disorders, anxiety, and multiple sclerosis(31)

Multiple sclerosis is a disabling disease of the central nervous system

Still, it is best to consult a doctor experienced in cannabis use to determine the proper CBD dose for HIV. 

How Long Does CBD Take to Help With HIV?

How long CBD takes to help with HIV symptoms depends on several factors, including the administration route, individual body weight, the type of CBD, and CBD potency.

For instance, the onset time of CBD via the sublingual route is between 15 and 30 minutes(32)

How Long Will CBD Help With HIV?

How long CBD will last after it starts to help with HIV symptoms depends on its bioavailability and half-life.

Bioavailability is the extent to which a particular substance becomes entirely available to its intended biological destinations. 

Meanwhile, half-life refers to the length of time needed for the concentration of a specific drug to decrease by 50% of its starting dose. 

About 94% to 97% of a substance will have been eliminated after four to five half-lives(33)

CBD’s bioavailability via the sublingual route is between 6% and 20%(34). In addition, CBD is reported to have a half-life between 1.4 and 10.9 hours following oromucosal spray(35)

How to Choose the Right CBD for HIV

CBD brands aim to offer various CBD products in different formats, potencies, and concentrations. However, HIV patients should consider the following when choosing the best CBD oil products for their condition:

  1. Always seek medical advice from a licensed doctor versed in cannabis use
  2. Choose a CBD brand that is transparent with its farming practices. Legitimate producers grow hemp in accordance with the United States Department of Agriculture (USDA), state, and tribal plans.
  3. Make sure that the company has enlisted the services of a third-party laboratory to test all of its products. 
  4. Opt for CBD brands that include a disclaimer label on their products. For instance, the FDA does not advertise cannabidiol as a dietary supplement(36).
  5.  Learn about the different CBD extracts. A full-spectrum CBD product contains all compounds of the cannabis plant, including essential oils. It also has less than 0.3% of THC

Moreover, this CBD variant is known to provide the entourage effect due to the presence of all cannabis compounds. 

The entourage effect is a concept wherein the biologically active compounds of cannabis work better when administered together. 

The Frontiers in Plant Science study hypothesized that the entourage effect in full-spectrum hemp extracts may produce better therapeutic benefits than pure CBD(37)

Meanwhile, broad-spectrum CBD also contains all of the natural compounds of cannabis except for THC. Lastly, CBD isolates are made of pure cannabidiol

Is CBD Safe for HIV?

The WHO (World Health Organization) has reported that cannabidiol has a good safety profile(38).

Moreover, a review from Current Drug Safety stated that chronic use and high doses of CBD up to 1,500mg per day are well tolerated in humans(39)

Still, you should consult a doctor versed in cannabis use, primarily if you are considering using CBD for HIV for the first time. Doctors can advise HIV patients whether CBD can benefit them.

Risks and Side Effects of Using CBD for HIV

CBD may carry some risks and induce minor side effects, including(40)

  • Fatigue 
  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness 

However, individuals diagnosed with HIV may experience diarrhea(41). Since one of the side effects of CBD is diarrhea(42), make sure to consult your healthcare provider before you take CBD for HIV. 

Another cause for concern is the inaccuracy of labeling of CBD extracts sold online. 

In 2019, about 70% of 240 CBD-infused products commercially available online and in retail stores were reported to be highly contaminated with heavy metals(43).  

In addition, the FDA warns against the use of unapproved CBD products with unproven medical claims. The agency stresses that these items could be produced with unsafe manufacturing practices(44)

More importantly, since the FDA has not evaluated these products to determine their proper dosage, the unapproved CBD items may interact with other drugs and cause detrimental side effects or other safety concerns(45)

Legality of CBD

The United States Congress ratified the 2018 Farm Bill, decriminalizing the commercial use of industrial hemp and products obtained from hemp plants(46)

The bill indicates that Cannabis sativa L. and other derivatives of cannabis with no more than 0.3% THC content on a dry weight basis are deemed legal under federal law(47).

Some states have passed laws allowing the use of recreational and medical cannabis

In New York, adults 21 years and older can buy up to three ounces or 85 grams of cannabis flower and 24 grams of concentrated cannabis(48). Edibles like CBD gummies and other CBD formats like oils, tinctures, and vapes can also be acquired. However, they can only buy cannabis products from a state-licensed dispensary.

You may also check government reports and journals online using a digital object identifier (DOI) to know more about CBD and various state laws. 

Still, remember that even if a specific state law indicates that CBD is legal, the only FDA-approved CBD drug is Epidiolex, used to treat rare and severe forms of epilepsy and seizures associated with tuberous sclerosis complex (TSC) in patients one year of age and older(49).

Product Frequently
Asked Questions

  • How can CBD help with HIV?

    Research regarding the effects of CBD on HIV is limited. However, a study suggests that CBD may help with chemotherapy-induced neuropathy and that Sativex, a 1:1 CBD to THC ratio, may effectively treat neuropathy associated with HIV/AIDs and multiple sclerosis(50)

    Meanwhile, a 2020 research article mentioned an anecdotal report on CBD’s purported antiviral properties, saying it may help manage HIV symptoms(51).

  • What evidence or research exists to say that CBD helps with HIV?

    There is limited research saying that CBD helps with HIV. However, sleep disturbances are common among people with HIV(52).

    Preliminary research suggests that CBD may have therapeutic potential for the treatment of insomnia(53). 

    The non-psychoactive compound may also hold promise for excessive daytime sleepiness and REM (rapid eye movement) sleep behavior disorder(54).

  • Is there any evidence that CBD can make HIV worse?

    No evidence suggests that CBD can make HIV worse. However, as the virus multiplies and destroys one’s immune cells, the cells in the body may not fight off germs anymore, leading to symptomatic HIV infection like diarrhea, fatigue, and weight loss(55)

    Fatigue and diarrhea are minor side effects of CBD(56).

  • Will CBD interact with any current medication I may be taking for HIV?

    CBD may interact with HIV antivirals because these substances use the cytochrome P450 enzyme system(57)

    Cytochrome P450 is a family of liver enzymes that metabolizes most pharmaceutical drugs. 

    CBD at high doses may inhibit the activity of these enzymes, increasing the prescription drugs’ effect and duration of action(58).

  • Are there other treatments I should consider alongside CBD to help with HIV?

    ART or antiretroviral therapy involves taking a combination of HIV treatment regimens each day. 

    No medicine can heal HIV. Although ART does not cure HIV, it may help HIV patients live longer, healthier lives. It also lessens the risk of HIV transmissions(59).

    However, if you plan to take HIV medications simultaneously with CBD, make sure to ask your doctor’s permission. They may also recommend the best medicine for HIV positive. 

    Remember that CBD is not a biologically inert (not generally reactive) compound, meaning CBD may trigger drug interactions when administered with other medications(60)

  • Can I fail a drug test if I use CBD for HIV?

    CBD does not induce a euphoric high(61). Nevertheless, some CBD products have traces of THC that may build up in the body when taken regularly in a span of four to six days(62)

    An increased THC level in the bloodstream may result in a positive drug test.

  • What is the dosage for HIV?

    The FDA has not recognized CBD as a medical treatment for HIV. Hence, there is no standard CBD dosage for such a condition. 

    However, doses between 10mg and 100mg per day may help with inflammation(63). Inflammation is also associated with HIV infection(64)


  1. HIV/AIDS
    https://www.who.int/news-room/fact-sheets/detail/hiv-aids
  2. CD4 Lymphocyte Count
    https://medlineplus.gov/lab-tests/cd4-lymphocyte-count/
  3. Ibid.
  4. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  5. Ibid.
  6. Ibid.
  7. Immune Responses Regulated by Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/
  8. HIV and Inflammation: Mechanisms and Consequences
    https://link.springer.com/article/10.1007/s11904-012-0118-8
  9. Cannabidiol (CBD) Induces Functional Tregs in Response to Low-Level T Cell Activation
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327652/
  10. Regulatory T Cells (TREG) and Their Roles in Immune System With Respect to Immunopathological Disorders
    https://pubmed.ncbi.nlm.nih.gov/20672742/
  11. Chronic Pain in HIV
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252379/
  12. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  13. The Power of the Placebo Effect
    https://www.health.harvard.edu/mental-health/the-power-of-the-placebo-effect
  14. Selective Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta-analysis
    https://journals.lww.com/anesthesia-analgesia/Fulltext/2017/11000/Selective_Cannabinoids_for_Chronic_Neuropathic.32.aspx
  15. Cannabinoids in the Management of Difficult to Treat Pain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/
  16. Neuroprotective Effect of Cannabidiol Against Hydrogen Peroxide in Hippocampal Neuron Culture
    https://www.liebertpub.com/doi/10.1089/can.2019.0102
  17. Making Sense of How HIV Kills Infected CD4 T Cells: Implications for HIV Cure
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452072/
  18. Short-Term Effects of Cannabinoids in Patients With HIV-1 Infection: A Randomized, Placebo-Controlled Clinical Trial
    https://pubmed.ncbi.nlm.nih.gov/12965981/
  19. Ibid.
  20. Cannabis Study Reveals How CBD Offsets the Psychiatric Side-Effects of THC
    https://www.sciencedaily.com/releases/2019/09/190930131115.htm
  21. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  22. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  23. Toxicology of E-Cigarette Constituents
    https://www.ncbi.nlm.nih.gov/books/NBK507184/
  24. HIV/AIDS
    https://www.mayoclinic.org/diseases-conditions/hiv-aids/symptoms-causes/syc-20373524
  25. Is It Safe to Vape CBD?
    https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/
  26. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964757/
  27. CBD: A Patient’s Guide to Medicinal Cannabis, page. 105.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  28. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  29. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  30. Systemic Effects of Inflammation on Health during Chronic HIV Infection
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012895/
  31. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  32. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  33. Half-Life
    https://www.ncbi.nlm.nih.gov/books/NBK554498/
  34. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  35. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  36. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  37. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain
    https://www.frontiersin.org/articles/10.3389/fpls.2018.01969/full
  38. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  39. Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  40. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  41. HIV/AIDS
    https://www.mayoclinic.org/diseases-conditions/hiv-aids/symptoms-causes/syc-20373524
  42. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  43. Report: Majority Of Commercially Available CBD Products “Contaminated” With Heavy Metals
    https://norml.org/news/2019/05/23/report-majority-of-commercially-available-cbd-products-contaminated-with-heavy-metals
  44. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
    https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
  45. Ibid.
  46. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  47. Ibid.
  48. Social Equity and Responsible Access to Adult-Use Cannabis for New Yorkers Ages 21 and Over
    https://cannabis.ny.gov/adult-use
  49. FDA Approves New Indication for Drug Containing an Active Ingredient Derived from Cannabis to Treat Seizures in Rare Genetic Disease
    https://www.fda.gov/news-events/press-announcements/fda-approves-new-indication-drug-containing-active-ingredient-derived-cannabis-treat-seizures-rare
  50. Oral Cannabinoids In People Living With Hiv On Effective Antiretroviral Therapy: Ctn Pt028—Study Protocol For A Pilot Randomised Trial To Assess Safety, Tolerability And Effect On Immune Activation
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340429/
  51. Cannabidiol for Viral Diseases: Hype or Hope?
    https://www.liebertpub.com/doi/10.1089/can.2019.0060
  52. Sleep Disturbances in Persons Living with HIV
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543776/
  53. Cannabis, Cannabinoids, and Sleep: a Review of the Literature
    https://pubmed.ncbi.nlm.nih.gov/28349316/
  54. Ibid.
  55. HIV/AIDS
    https://www.mayoclinic.org/diseases-conditions/hiv-aids/symptoms-causes/syc-20373524
  56. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  57. Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497396/
  58. Healing With CBD, pages 114-115.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  59. HIV Treatment: The Basics
    https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-treatment-basics
  60. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  61. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  62. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  63. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  64. Systemic Effects of Inflammation on Health during Chronic HIV Infection
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012895/
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