Best CBD Oil for BPD
Are you considering cannabidiol (CBD) as a way to manage symptoms of borderline personality disorder (BPD) such as mood swings, anxiety, and depression? CBD Clinicals has information that can help you choose the best CBD oil for BPD.
Best CBD Oil for BPD 2024
- Spruce 750mg Lab Grade CBD Oil Editor's Pick
- NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil Best Organic
- Spruce 2400mg Lab Grade CBD Oil Editor's Pick
- Avida Full Spectrum CBD Oil Tincture 500mg Best Seller
- cbdMD CBD Oil Tincture Natural 1500mg Best Natural Alternative
- CBDistillery THC Free CBD Oil Tinctures Best THC-Free
- cbdMD CBD Oil Tincture Natural 750mg Best Customer Rated
- NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil Best Starter
- Hemp Bombs 750mg CBD Oil Best Flavor Range
Compare the Best CBD Oil for BPD in 2022
Best CBD Oil for BPD
1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Mid-strength |
No other flavors |
|
Natural peppermint flavor |
|
|
Made from 100% organic and natural ingredients |
Overview
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Pure CBD hemp |
No other flavors |
|
All natural |
|
|
Approximately 300 drops total |
Overview
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Extra Strength |
Tastes bitter |
|
No artificial flavoring or colors |
No THC-free option |
|
Made from 100% organic and natural ingredients |
Overview
The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.
4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Light Spearmint flavor |
No other flavor |
|
Non-THC, Non-detected in drug test |
Overview
Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.
5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Various delicious flavors to choose from |
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options |
|
Has vegan, organic, and gluten-free ingredients |
|
|
Free shipping for this particular product within USA |
|
|
World-class customer service team |
Overview
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
60-Day Satisfaction Guarantee |
Dropper is a bit shaky |
|
Various strengths |
|
|
Oil extracted from aerial plant parts of US grown industrial hemp |
|
|
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices |
Overview
CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.
7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Pure CBD hemp |
No other flavors |
|
All natural |
A bit pricey compared to competitors |
|
Approximately 100 drops total |
Overview
This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.
8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Vegan and Gluten free |
Does not ship internationally |
|
Has a third-party lab test |
|
|
Wide variety of CBD strengths and sizes |
Overview
A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.
9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
| Pros | Cons |
|---|---|
|
Wide variety of flavors |
Incomplete information about the product |
|
Lab test results are complete |
Does not ship to all international countries |
|
30-day money-back guarantee |
Overview
Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.
How CBD May Help With BPD
Studies suggest that CBD (cannabidiol) oil creates chemical changes in the brain that may help individuals with borderline personality disorder (BPD) gain stability over their emotions(1).
Researchers have theorized that CBD contains mood-regulating properties that interact with the body’s endocannabinoid system (ECS)(2). The ECS controls vital body functions such as mood, memory, sleep, cognition, appetite, and immune system.
Results of a study suggested that depression can develop as a result of chronic exposure to elevated inflammatory cytokines(3).
Cytokines refer to the hormones produced by the immune system. These hormones can affect bodily tissue and brain function.
Inflammatory cytokines can lead to neuropsychiatric disorders and depression(4). Depression is a symptom of BPD(5).
Meanwhile, research suggests that CBD has anti-inflammatory properties and reduces neuropathic pain(6). CBD’s anti-inflammatory properties were also highlighted in a 2018 study (7).
Benefits of Using CBD for BPD
CBD works with the body’s endocannabinoid system by interacting with its receptors(8). Serotonin receptors 5-TH1A are one of the endocannabinoid receptors activated by CBD(9).
Serotonin is a hormone and neurotransmitter that stabilizes mood and causes the feeling of happiness. Most antidepressants and anti-anxiety medications also target these serotonin receptors to regulate mood.
BPD patients who suffer from anxiety and depression may have lowered serotonin levels(10). CBD may help regulate mood by reversing anxiety-like behavior(11).
CBD may also help improve the hippocampus’ functions by acting as a stimulant. The hippocampus is part of the central nervous system that regenerates neurons(12).
Individuals with symptoms of BPD like depression often have a smaller hippocampus(13). Thus, this behavior will be reduced by stimulating and regenerating its neurons.
Additionally, CBD products with or made from hemp oil may help individuals deal with BPD. Hemp oil contains omega-3 fatty acids(14) that support cognitive function and has anti-inflammatory effects on the brain(15).
Studies reveal that supplementing with omega-3 fatty acids can be an effective way to treat children and adults with mental health issues such as BPD(16).
How to Take CBD Oil for BPD
CBD products can be taken in different ways for BPD and other medical conditions, including:
- Oral ingestion for gummies and edibles
- Vaping
- Sublingual (under the tongue) administration for CBD oils and CBD tinctures
- Topical administration
Smoking CBD with a vape can be the fastest way to feel its benefits due to vapors leading straight to your bloodstream. You can usually feel its effects within 10 minutes(17).
However, vaping may cause lung damage(18).
Additionally, CBD oil is unregulated by the Food and Drug Administration (FDA) in the United States(19).
Ingredients from cannabis without CBD or THC may be used in foods and dietary supplements only if FD&C Act (Federal Food, Drug, and Cosmetic Act) requirements are met.
What Is the Best CBD Dosage for BPD?
There are currently no approved guidelines on CBD dosing(20). External factors such as age, weight, and severity of symptoms can affect the dosage.
Individuals should consult a doctor before using CBD oil or any CBD product. Medical professionals can recommend the best dosage for BPD and other medical conditions.
How Long Does CBD Take to Help With BPD?
The CBD form, administration, and dosage can influence how quickly CBD affects your body.
In general, users may feel the benefits of vaping CBD after 2 to 15 minutes of vaping(21). Meanwhile, CBD edibles such as gummies and capsules usually take effect within 30 to 90 minutes.
How Long Will CBD Help With BPD?
There are no current studies on the long-term effects of CBD oil for BPD. However, CBD may last in your system depending on the dosage and the frequency of consumption.
Generally, CBD remains in your system for two to five days and can extend to a few weeks(22).
How to Determine the Quality of CBD Oil for BPD
In choosing CBD products, look at product labels and specifications carefully. To get the full benefits of CBD oil, consider the following elements:
Hemp Source
Cannabis plants, including marijuana and hemp plants, may yield weak or strong extracts depending on the environment where they were cultivated.
If you want a potent CBD oil, purchase it from companies that produce organic non-GMO CBD products from hemp plants. Using low potent CBD oils may not effectively deal with your health or medical conditions(23).
Most hemp brands usually source their products from Colorado, Montana, Kentucky, and California.
Full-Spectrum CBD or Whole Plant CBD
Good quality CBD oil is manufactured using the entire plant, so all the natural compounds of the cannabis plant are present in the extract.
A study in 2020 has found that full-spectrum CBD oil is more effective in dealing with medical issues like neuropathic pain(24).
Third-Party Lab Tests
An independent laboratory test is solid evidence of a CBD product’s quality. Reliable CBD oil brands publish their third-party lab results on their product packaging or websites.
Third-party testing thoroughly analyzes the potency of CBD, searching for any contaminants in the products, like preservatives, metals, solvents, and pesticides.
Labeling Accuracy
Double-check the concentration of CBD and THC on the certificate of analysis (COA). The figures should match the ones indicated on the product label.
Labeling inaccuracy is a common issue with CBD products.
One study revealed that only around 31% of CBD products have accurate labels(25). Eighty-four CBD products sold online were analyzed, and researchers discovered that 43% of brands have a higher CBD concentration than stated.
Risks and Side Effects of Using CBD for BPD
Using CBD is relatively safe for humans and animals(26). If administered and used correctly, it may not have any adverse side effects.
CBD is a non-psychoactive cannabinoid, unlike tetrahydrocannabinol (THC), which is responsible for activating the feeling of being high.
In a 2017 pre-review report by the World Health Organization (WHO), it was stated that CBD is not addicting and does not have any potential for abuse(27).
However, using CBD may cause minor side effects if taken simultaneously with certain prescription medications such as antidepressants(28). These side effects may include:
- Sleepiness
- Fatigue
- Nausea
- Dry mouth
- Diarrhea
Talking to your doctor before considering using CBD products with antidepressants and other prescription drugs is the best course of action.
Legality of CBD
CBD oils and products with less than 0.3% THC are legal in the United States, as stated in the 2018 Farm Bill(29).
However, marijuana-derived CBD products are still illegal in many states(30). Be sure to check your state laws when planning to use CBD or travel with it.
Product Frequently
Asked Questions
-
How can CBD help with BPD?
CBD has mood-regulating properties that work with the body’s endocannabinoid system, allowing people with BPD to better deal with their symptoms(31).
-
What evidence or research exists to say that CBD helps with BPD?
CBD interacts with the endocannabinoid system(32). One ECS receptor is the 5-TH1A serotonin receptor for serotonin, the happy chemical.
Individuals with BPD also suffer from anxiety and depression caused by lowered serotonin levels(33).
CBD may help activate the brain’s 5-TH1A serotonin receptors and regulate mood(34).
-
Is there any evidence that CBD can make BPD worse?
CBD is generally safe and well tolerated by the body(35). It is also non-addictive based on a report by the WHO(36).
However, CBD may yield side effects like drowsiness, lightheadedness, nausea and diarrhea(37). CBD also interacts with other medications taken for BPD, like antidepressants(38).
If you plan to use CBD products with any of these medications, consult your doctor or medical health professional first.
-
Will CBD interact with any current medication I will be taking for BPD?
Using CBD products with prescription medicines like antipsychotics and antidepressants may cause side effects like sleepiness and fatigue(39). Antidepressants have been prescribed to BPD patients(40).
Consulting your doctor before using any CBD product is crucial if you are using it simultaneously with other medications.
-
Are there other treatments I should consider alongside CBD to help with BPD?
BPD is generally treated through psychotherapy and medication(41). Although the FDA has not officially authorized any drugs to treat BPD, certain medications like antidepressants can help cope with its symptoms(42).
CBD oil may be another method of treatment to regulate the different symptoms of BPD, such as anxiety, depression, and mood swings(43).
-
Can I fail a drug test if I use CBD for BPD?
Full-spectrum CBD contains THC, which is illegal in the United States if over 0.3%(44). When taken regularly over time, the accumulation of THC in the blood may lead to a positive drug test(45).
-
What is the dosage for BPD?
There are no set guidelines on the dosage of CBD for BPD(46). However, factors such as your weight, diet, and age can determine its effects.
Talk to your doctor before using CBD products for BPD, so they may recommend the right dosage for you.
-
Are there side effects to CBD oil for BPD?
There is no current study on the potential side effects of CBD oil for BPD.
However, taking CBD oil or any CBD products alongside medications such as antidepressants used to treat BPD can cause minor side effects to the body(47).
-
How can I take CBD oil for BPD?
CBD oil or any CBD products for BPD can be taken in numerous ways, depending on your preference. It can be taken orally, topically, or through vaping.
Consult your doctor for recommendations on what CBD oil and product is best for your needs.
-
Can CBD oil for BPD be legally purchased?
CBD oil is legal in the United States as long as it has less than 0.3% THC content(48).
However, some states have different laws regarding CBD use and selling. Check these laws before purchasing CBD products(49).
- Targeting the Endocannabinoid System in Borderline Personality Disorder: Corticolimbic and Hypothalamic Perspectives
https://pubmed.ncbi.nlm.nih.gov/32351183/#:~:text=Extensive%20expression%20of%20CB1%20and,the%20BPD%20population%20to%20date. - Cannabidiol for Mood Disorders: A Call for More Research
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918874/ - Inflammatory Cytokines in Depression: Neurobiological Mechanisms and Therapeutic Implications
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741070/ - Cytokines in Neuropathic Pain and Associated Depression
https://pubmed.ncbi.nlm.nih.gov/26437375/ - Borderline Personality Disorder
https://www.nimh.nih.gov/health/topics/borderline-personality-disorder - Antioxidative and Anti-Inflammatory Properties of Cannabidiol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/ - Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis
https://pubmed.ncbi.nlm.nih.gov/29632236/ - Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877694/ - Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/ - What has serotonin to do with depression?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471964/ - Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/ - Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908414/ - Depression and the Hippocampus: Cause or Effect?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733566/ - The cardiac and haemostatic effects of dietary hempseed
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868018/ - The Anti-Inflammatory Role of Omega-3 Polyunsaturated Fatty Acids Metabolites in Pre-Clinical Models of Psychiatric, Neurodegenerative, and Neurological Disorders
https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00122/full - omega-3 Fatty acid treatment of women with borderline personality disorder: a double-blind, placebo-controlled pilot study
https://pubmed.ncbi.nlm.nih.gov/12505817/ - Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers
https://www.tandfonline.com/doi/full/10.3109/03639041003657295 - Is It Safe to Vape CBD?
https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/ - FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd - CBD Dosage: Figuring Out How Much to Take
https://www.healthline.com/health/cbd-dosage#how-much-to-take - CBD for Arthritis Pain: What You Should Know
https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain - How Long Does CBD Stay in Your System?
https://www.healthline.com/health/how-long-does-cbd-stay-in-your-system#:~:text=CBD%20typically%20stays%20in%20your,in%20their%20system%20for%20weeks. - Mapping cannabis potency in medical and recreational programs in the United States
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230167 - The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281216/ - Labeling Accuracy of Cannabidiol Extracts Sold Online
https://jamanetwork.com/journals/jama/fullarticle/2661569 - Cannabidiol (CBD), page 5.
https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf - Cannabinoid (CBD) Pre-Review Report, page 14.
https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf - CBD and other medications: Proceed with caution
https://www.health.harvard.edu/blog/cbd-and-other-medications-proceed-with-caution-2021011121743#:~:text=In%20other%20words%2C%20taking%20CBD,increased%20sleepiness%2C%20fatigue%2C%20and%20possibly - Hemp Production and the 2018 Farm Bill
https://www.fda.gov/news-events/congressional-testimony/hemp-production-and-2018-farm-bill-07252019 - State Medical Cannabis Laws
https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx - Updated: CBD and THC combine antidepressant and antipsychotic actions, suggesting a therapeutic potential in mood and related disorders.
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0447.2011.01687.x - Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877694/ - Serotonin, personality and borderline personality disorder
https://pubmed.ncbi.nlm.nih.gov/26983967/ - Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/ - Cannabidiol (CBD), page 5.
https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf - Cannabinoid (CBD) Pre-Review Report, page 14.
https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700#:~:text=Though%20it’s%20often%20well%2Dtolerated,dosage%20of%20CBD%20in%20products. - CBD and other medications: Proceed with caution
https://www.health.harvard.edu/blog/cbd-and-other-medications-proceed-with-caution-2021011121743#:~:text=In%20other%20words%2C%20taking%20CBD,increased%20sleepiness%2C%20fatigue%2C%20and%20possibly - ibid.
- Borderline personality disorder: current drug treatments and future prospects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513859/ - Borderline personality disorder
https://www.mayoclinic.org/diseases-conditions/borderline-personality-disorder/diagnosis-treatment/drc-20370242 - ibid
- The Endocannabinoid System, Aggression, and the Violence of Synthetic Cannabinoid Use, Borderline Personality Disorder, Antisocial Personality Disorder, and Other Psychiatric Disorders
https://pubmed.ncbi.nlm.nih.gov/29636670/ - Hemp Production and the 2018 Farm Bill
https://www.fda.gov/news-events/congressional-testimony/hemp-production-and-2018-farm-bill-07252019 - Can You Take CBD and Pass a Drug Test?
https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/ - CBD Dosage: Figuring Out How Much to Take
https://www.healthline.com/health/cbd-dosage#how-much-to-take - CBD and other medications: Proceed with caution
https://www.health.harvard.edu/blog/cbd-and-other-medications-proceed-with-caution-2021011121743#:~:text=In%20other%20words%2C%20taking%20CBD,increased%20sleepiness%2C%20fatigue%2C%20and%20possibly - Hemp Production and the 2018 Farm Bill
https://www.fda.gov/news-events/congressional-testimony/hemp-production-and-2018-farm-bill-07252019 - State Medical Cannabis Laws
https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx
Featured Brands
What’s new
Why Trust CBD Clinicals?
Our Medical Team
The following medical professionals are part of the CBD Clinicals’ medical review team. We focus on ensuring our content is accurate, evidence-based, current and trustworthy.
Read more
Our Editorial Process
The CBD Clinicals Team is committed to producing CBD-related content that is current, factual, unbiased, evidence-based, and medically reviewed.
Read more
Our Ethical Principles
We are committed to helping individual consumers realize the full benefits of CBD to improve their health and that of their families (including their dogs, cats & other pets).
Read more