'

Best CBD Oil for Back Pain

Are you considering CBD to help alleviate back pain episodes? CBD Clinicals has the information you need about the compound so you can choose the best CBD oil for back pain.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil


3.5 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the Best CBD Oil for Back Pain in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

1.0 out of 5

5.0 out of 5

Best CBD Oil for Back Pain

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score
3.5
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes  Shipping not specified on website
 More flavors to choose from  3rd party lab result is currently not available on website
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Pros
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes
 More flavors to choose from
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Cons
 Shipping not specified on website
 3rd party lab result is currently not available on website
Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With Back Pain

Back pain is a medical problem affecting eight out of ten people at some point in their lives(1). The pain can start from a muscle aching to a stabbing sensation that may radiate down one’s leg(2)

Cannabidiol, also known as CBD, is an active compound of cannabis. While CBD is an essential substance of medical marijuana, the compound is mainly derived from hemp plants

Currently, there is limited research regarding CBD and its effects on back pain. However, CBD’s pain-relieving properties(3) and its activity in the ECS (endocannabinoid system) may elucidate how CBD may help with back pain

The ECS is responsible for maintaining bodily balance or homeostasis. 

The system regulates various functions, such as emotional processing, learning, memory, sleep, appetite, temperature control, inflammatory and immune response, and pain control(4).  

The ECS is composed of a vast network of cellular receptors and chemical signals present throughout the brain and body. 

The cannabinoid receptors type 1 (CB1 receptors) found within the pain pathways of the central nervous system may affect CBD-induced analgesia (loss of pain perception)(5)

In addition, CB1 receptors are also responsible for the psychoactive effects of THC (tetrahydrocannabinol)(6), which is the mind-altering chemical constituent of cannabis plants

CBD is believed to behave as a non-competitive negative allosteric modulator of CB1 receptors and thus may reduce THC’s efficacy and potency(7). THC may act as a partial agonist at cannabinoid receptors

A study suggests that allosteric modulators of CB1 receptors like CBD may potentially treat central nervous system diseases and peripheral disorders while helping avoid the adverse effect linked to the agonism of CB1 receptors(8)

Agonism is a process where a particular drug activates specific receptors in the brain. 

Meanwhile, CB2 receptors mainly present in immune cells may affect CBD-induced anti-inflammatory properties(9)

The therapeutic potential of CBD and its activity in the ECS are promising. However, since CBD and back pain research are still in their infancy, more studies are needed to substantiate reports that CBD may help with back pain. 

Benefits of Using CBD for Back Pain

A 2020 review from the Journal of Opioid Management suggested that hemp-derived CBD in transdermal creams may provide significant symptomatic and pain relief from acute and chronic back pain(10)

Transdermal refers to the administration route where active ingredients like CBD are delivered across the skin for systematic distribution. 

Research regarding the benefits of using CBD for back pain management is still in its infancy. However, there are available studies regarding the effects of CBD on various medical conditions related to pain. 

Some individuals have tried CBD for arthritis pain and reported noticeable pain relief(11). Arthritis causes joint pain(12)

Meanwhile, a study from Cell Death and Disease suggested CBD’s potential as an adjuvant treatment in rheumatoid arthritis(13).

Rheumatoid arthritis is an autoimmune disease that causes inflammation and pain in and around the joints, affecting other body organs. 

Meanwhile, an adjuvant refers to a substance that enhances the immune response to an antigen. 

Fibromyalgia, a condition that causes pain all over the body, affects 4 million adults in the United States(14)

 An extensive online survey published in the Journal of Pain suggested that CBD use is common among individuals with fibromyalgia(15)

The 2021 survey consisted of 2,701 participants with fibromyalgia, mainly from the U.S. Overall, 32.4% reported current CBD use, while 29.4% reported past CBD use to help manage fibromyalgia symptoms, particularly pain(16).   

More importantly, CBD is relatively safe(17), making it a potential therapeutic candidate for various diseases. 

A review from Current Drug Safety reported that humans may tolerate high doses of up to 1,500 mg of CBD daily(18)

Although these findings seem promising, they are inconclusive. Therefore, more longitudinal research is warranted to determine the benefits of using CBD oil for pain, particularly back pain

How to Use CBD Oil for Back Pain

One of the purported health benefits of CBD is its potential to alleviate chronic pain(19). If you want to use CBD oil and other CBD-derived products for back pain and overall wellness, below are important details to consider: 

Administration Methods

The most common CBD administration methods are as follows:

  • Inhalation
  • Ingestion
  • Sublingual (under the tongue) route
  • Topical absorption 

Inhaling CBD using vape pens is the fastest way to benefit from the compound(20). The onset time of CBD via the inhalation route is between 2 to 15 minutes, and its effects usually last for 2 to 4 hours(21)

However, Mayo Clinic says that smokers are at a high risk of experiencing back pain because smoking prompts more coughing and can decrease blood flow to the spine(22)

In addition, it is reported that most lung injury cases in the U.S. are linked to vaping(23)

Unlike smoking, taking CBD sublingually does not expose the lungs to heat. Hence, you can avoid dealing with a smoky taste, dry mouth, and throat irritation(24).

The capillaries under the tongue and within the mouth absorb CBD into the bloodstream before being swallowed(25)

You may use a dropper to dispense CBD oil straight into your mouth. 

Usually, the onset time of CBD via the sublingual route is between 15 and 30 minutes, and the effect of CBD may last from 2 to 4 hours(26).   

Using CBD oil topically may also provide localized relief. The onset time of CBD via the topical route is between 15 and 30 minutes, and its effects may last for 2 to 4 hours(27)

CBD Dosage

The FDA (Food and Drug Administration) has not approved CBD as a medical treatment for back pain. Thus, there is no standard CBD dosage for such a condition.

However, mid-range doses between 10mg and 100mg of CBD daily may be effective for pain(28)

Meanwhile, a case series and literature review from the Journal of Opioid Management hypothesized that hemp-derived CBD in transdermal creams may provide pain relief for acute and chronic back pain(29)

The study involved two opioid-naive patients with neuropathic and radicular pain. 

Neuropathic pain is experienced when there is damage to the nerves, whereas radicular pain is a sensation radiating from the back and hip into the legs and through the spine.  

The patients used CBD cream containing 400mg of CBD per two ounces and reported symptomatic improvement and pain relief(30)

Still, it is best to talk with a healthcare professional experienced in cannabis use for accurate dosing. 

How Long Does CBD Take to Help With Back Pain?

How long CBD takes to help with back pain depends on several factors, including the administration route, the individual’s body weight, and CBD type. 

For instance, you may feel the effect of CBD via the sublingual route within 15 to 30 minutes(31). For topical absorption, CBD’s onset time is also between 15 and 30 minutes(32)

How Long Will CBD Help With Back Pain?

How long CBD’s effects will last after the compound starts to help with back pain depends on its bioavailability.

Bioavailability is the extent to which a particular substance becomes entirely available to its intended biological destinations. 

With high bioavailability, the body absorbs more of the appropriate compound without you having to take higher doses.

The bioavailability of CBD via the sublingual route is between 6% and 20%(33).

Meanwhile, since CBD does not enter the bloodstream when applied to the skin, its bioavailability is zero via topical application(34)

How to Choose the Right CBD Product

Various CBD companies like NuLeaf Naturals, Medterra, CBDistillery, and Charlotte’s Web are dedicated to offering the best CBD product for their customers. 

However, with so many CBD brands promising the best CBD products in the market, it can be challenging to choose the right one for your specific needs. 

Below are a few pertinent factors to consider that may help you sort through CBD items to find the right quality products: 

CBD Extracts

A full-spectrum CBD product contains all compounds of the cannabis plant, including CBD and other cannabinoids, essential oils, flavonoids, and terpenes

Full-spectrum CBD oil also has less than 0.3% THC. Additionally, this CBD variant is known to provide the entourage effect due to the presence of all cannabis compounds. 

The entourage effect is a theory where the biologically active compounds of cannabis work better when administered together. 

A Frontiers in Plant Science study hypothesized that, due to the entourage effect,  full-spectrum hemp extracts may produce better therapeutic benefits than pure CBD(35)

Full-spectrum CBD oil has all the cannabis plant compounds, including flavonoids and terpenes.

Flavonoids are active compounds found in cannabis that are believed to have antioxidant, anti-inflammatory, and antiviral actions(36)

On the other hand, terpenes are the components of essential oils responsible for the aroma of cannabis(37).

Broad-spectrum CBD oil also has all of the natural compounds of cannabis. However, it is THC-free. Lastly, CBD isolates refer to the type of CBD that contains cannabidiol in its pure form.

Extraction Method 

The extraction method is the process where CBD oil is derived from cannabis

Ethanol, solvent, or CO2 extraction (carbon dioxide extraction method) is preferred to create a safe CBD product(38). Meanwhile, extraction techniques utilizing hexane or butane may leave harmful residues, like heavy metals and pesticides.

Other Ingredients 

Always opt for CBD products made from U.S.-grown hemp or organic hemp, if possible. Make sure to choose CBD formats made with natural ingredients, non-GMO hemp, or free from gluten.  

Most CBD formats available in the market include tinctures, vapes, CBD topicals, like salves and lotions, and edibles like CBD gummies

Carrier Oils 

After extracting CBD from the hemp plant, CBD manufacturers infuse cannabidiol into a carrier oil. 

The most commonly utilized carrier oils are MCT oil (medium-chain triglyceride oil), coconut oil, and hempseed oil(39). Although most people interchangeably use hempseed oil and hemp oil, they are different from each other.

Hemp oil is an essential oil that comes from the flowers and leaves of hemp plants, while hempseed oil is made from the pressed seeds of hemp.

Hempseed oil is packed with nutrients and fatty acids. However, it does not contain CBD(40).  

Third-Party Lab Testing

The best way to check whether a CBD product contains what the brand says it does is to look at the lab reports and COAs (certificates of analysis).   

The COAs or lab test results must be up-to-date and come from a trusted third-party laboratory. Therefore, ensure that the information on the COA matches the claims on the product label.  

Brand Reputation

Many CBD brands are dedicated to offering only high-quality CBD products to their customers. 

Still, make sure to research the CBD company to verify if it is a trusted brand. Read customer reviews to get more insights into the manufacturer and its products. 

Risks and Side Effects of Using CBD for Back Pain

Although CBD has numerous therapeutic potential(41), this non-psychoactive compound may also carry some risks and induce minor side effects, such as(42)

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue 

Another cause for concern is the probability of drug interactions. CBD at high doses may inhibit the activity of cytochrome P450(43), a family of liver enzymes that metabolize most pharmaceutical drugs. 

Over-the-counter pain relievers, including NSAIDs (nonsteroidal anti-inflammatory drugs), may help relieve back pain(44)

Meanwhile, antidepressants like duloxetine and tricyclic drugs may be effective with chronic back pain independent of their effect on depression(45)

However, NSAIDs use the cytochrome P450 enzyme system and may interact with CBD(46). 

On the other hand, CYP2D6, an enzyme primarily expressed in the liver, metabolizes antidepressants like tricyclic drugs(47). Since CBD is a potent inhibitor of this particular enzyme, the compound may increase the serum concentrations of substances that CYP2D6 metabolizes. 

Legality of CBD

The United States Congress ratified the 2018 Farm Bill, decriminalizing the commercial use of industrial hemp and products obtained from hemp plants(48).

The Farm Bill states that Cannabis sativa L. and other derivatives of cannabis with less than 0.3% THC content on a dry weight basis are considered legal under federal law(49).

Some states have passed laws allowing the use of recreational and medical marijuana. Nevertheless, these state laws do not change that, under federal law, marijuana is still deemed as a drug with high abuse potential with no accepted medicinal use(50)

Rules and regulations regarding medical cannabis may be confusing. Hence, consumers should read various state laws. 

Take California, for example. In October 2021, California Governor Gavin Newsom signed Assembly Bill No. 45 into law(51)

The bill allows the inclusion of hemp and cannabinoids, extracts, or hemp derivatives in dietary supplements, food and beverages, cosmetics, and processed pet food, provided that they contain no more than 0.3% THC(52).

Meanwhile, in Texas, the local government passed laws in June 2019, creating a state industrial hemp program(53). 

Under House Bill 1325, the Texas Department of State Health Services is in charge of issuing licenses to people who want to manufacture or sell consumable hemp-derived products in the Lone Star State(54)

Colorado is another state that permits recreational and medical marijuana use(55). The local government decriminalized the use of marijuana by passing Amendment 64 to the Colorado Constitution in November 2012.    

Still, even if a specific state law indicates that CBD use is legal, the only FDA-approved CBD drug is Epidiolex, used to treat rare and severe forms of epilepsy.

Product Frequently
Asked Questions

  • How can CBD help with back pain?

    CBD has purported pain-relieving effects(56). Such benefits may help with common medical problems like back pain.

  • What evidence or research exists to say that CBD helps with back pain?

    A 2020 study showed that CBD may help with chronic and acute back pain(57).

  • Is there any evidence that CBD can make back pain worse?

    No evidence suggests that CBD can make back pain worse. However, some types of back pain may worsen and be accompanied by unexplained weight loss(58). Thus, it is best to consult a doctor versed in cannabis use before using CBD. 

    One of the side effects of CBD is reduced appetite(59), which is also a physiologic factor associated with unexplained weight loss(60).

  • Will CBD interact with any current medication I may be taking for back pain?

    NSAIDs may help relieve back pain(61). However, NSAIDs may interact with CBD(62)

    Cytochrome P450, a family of liver enzymes, metabolizes NSAIDs. At high doses, CBD may potently inhibit these enzymes’ activities(63).

  • Are there other treatments I should consider alongside CBD to help with back pain?

    Aside from NSAIDs, your doctor may also recommend muscle relaxants, topical pain relievers, narcotics like opioids, and antidepressants, depending on the type of back pain you have(64)

    Hence, be sure to talk with your doctor before you use other treatments alongside CBD to help with back pain. This way, they can advise you regarding risks and possible drug interactions.

  • Can I fail a drug test if I use CBD for back pain?

    You will not get a positive drug test if you use CBD topicals for back pain. CBD topicals do not enter the bloodstream(65)

    Additionally, CBD does not cause a euphoric effect(66). However, some CBD products have trace amounts of THC that may build up in your body when taken frequently via ingestion or inhalation(67)

    An increased THC level in the bloodstream may result in a positive drug test.

  • What is the dosage for back pain?

    The FDA does not recognize CBD as a medical treatment for back pain. Thus, there is no standard CBD dosage for such a condition.

    However, doses between 10mg and 100mg of CBD daily may be effective for pain(68).

  • Is CBD legal?

    CBD and other derivatives of cannabis with less than 0.3% THC content on a dry weight basis are deemed legal under federal law(69).

    Still, state laws vary. For this reason, it is essential to learn various rules and regulations regarding CBD use for back pain and other medical conditions.

  • Is CBD safe to use?

    According to the WHO (World Health Organization), cannabidiol is generally well tolerated. The compound also has a good safety profile(70).


  1. Back Pain
    https://medlineplus.gov/backpain.html
  2. Back pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/symptoms-causes/syc-20369906
  3. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  4. The Endocannabinoid System: Essential and Mysterious
    https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
  5. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  6. Healing With CBD, page 279.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  7. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  8. Cannabidiol Is a Negative Allosteric Modulator of the Cannabinoid CB1 Receptor
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621983/
  9. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  10. Cannabidiol (CBD) as a Treatment of Acute and Chronic Back Pain: A Case Series and Literature Review
    https://pubmed.ncbi.nlm.nih.gov/32421842/
  11. CBD for Arthritis Pain: What You Should Know
    https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain
  12. Arthritis
    https://my.clevelandclinic.org/health/diseases/12061-arthritis
  13. Cannabidiol (CBD): A Killer for Inflammatory Rheumatoid Arthritis Synovial Fibroblasts
    https://www.nature.com/articles/s41419-020-02892-1
  14. Fibromyalgia
    https://www.cdc.gov/arthritis/basics/fibromyalgia.htm
  15. Cannabidiol Use for Fibromyalgia: Prevalence of Use and Perceptions of Effectiveness in a Large Online Survey
    https://pubmed.ncbi.nlm.nih.gov/33400996/
  16. Ibid.
  17. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  18. Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  19. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  20. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  21. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  22. Back pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/symptoms-causes/syc-20369906
  23. Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products
    https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html
  24. CBD: A Patient’s Guide to Medicinal Cannabis, page. 105.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  25. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  26. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  27. Healing With CBD, page 193.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  28. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  29. Cannabidiol (CBD) as a Treatment of Acute and Chronic Back Pain: A Case Series and Literature Review
    https://pubmed.ncbi.nlm.nih.gov/32421842/
  30. Ibid.
  31. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  32. Healing With CBD, page 193.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  33. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  34. Healing With CBD, page 210.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  35. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain
    https://www.frontiersin.org/articles/10.3389/fpls.2018.01969/full
  36. Flavonoids As Antioxidants
    https://pubmed.ncbi.nlm.nih.gov/10924197/
  37. The Cannabis Terpenes
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763918/
  38. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  39. Healing With CBD, page 205.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  40. Hemp Seed Oil Properties
    https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
  41. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  42. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  43. Healing With CBD, page 114.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  44. Back pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/diagnosis-treatment/drc-20369911
  45. Ibid.
  46. Healing With CBD, pages 115-116
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  47. Medical Cannabis: Adverse Effects & Drug Interactions
    https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  48. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  49. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  50. The Federal Controlled Substances Act: Schedules and Pharmacy Registration
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839489/
  51. Assembly Bill No. 45
    https://leginfo.legislature.ca.gov/faces/billTextClient.xhtml?bill_id=202120220AB45
  52. Ibid.
  53. Cannabis and the Law
    https://guides.sll.texas.gov/cannabis/cbd
  54. Ibid.
  55. Legal Marijuana Use in Colorado
    https://cannabis.colorado.gov/legal-marijuana-use-in-colorado
  56. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  57. Cannabidiol (CBD) as a Treatment of Acute and Chronic Back Pain: A Case Series and Literature Review
    https://pubmed.ncbi.nlm.nih.gov/32421842/
  58. Back Pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/symptoms-causes/syc-20369906
  59. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  60. Unintentional Weight Loss in Older Adults
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050948/
  61. Back Pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/diagnosis-treatment/drc-20369911
  62. Healing With CBD, pages 115-116
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  63. Healing With CBD, page 114.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  64. Back Pain
    https://www.mayoclinic.org/diseases-conditions/back-pain/diagnosis-treatment/drc-20369911
  65. Healing With CBD, page 210.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  66. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  67. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  68. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  69. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  70. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
Featured Brands
What’s new

Why Trust CBD Clinicals?

Our Medical Team

The following medical professionals are part of the CBD Clinicals’ medical review team. We focus on ensuring our content is accurate, evidence-based, current and trustworthy.

Read more

Our Editorial Process

The CBD Clinicals Team is committed to producing CBD-related content that is current, factual, unbiased, evidence-based, and medically reviewed.

Read more

Our Ethical Principles

We are committed to helping individual consumers realize the full benefits of CBD to improve their health and that of their families (including their dogs, cats & other pets).

Read more

Our mission at CBD Clinicals is to provide the most applicable, medically reviewed CBD content on the web.

Scroll to Top