Best CBD Oil for Appetite Management

CBD oil is often marketed for its potential health benefits. If you are curious whether this cannabis product may help with appetite, CBD Clinicals gives you CBD information that may help with overall wellness.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil

4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil

5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg

4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg

4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures

4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil

3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil

3.7 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the best CBD Oil for Appetite Management in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 750mg Lab Grade CBD Oil
4.8 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5
5.0 out of 5
3.5 out of 5
3.0 out of 5
5.0 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5
5.0 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5
4.5 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5
2.5 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5
4.5 out of 5
3.5 out of 5
2.5 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.7 out of 5
2.5 out of 5
3.5 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
1.0 out of 5
5.0 out of 5

The Best CBD Oil for Appetite Management

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score

4.8

CBDC Evaluation Table/Score
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Mid-strength

No other flavors

Natural peppermint flavor

Made from 100% organic and natural ingredients

Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Pure CBD hemp

No other flavors

All natural

Approximately 300 drops total

Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Extra Strength

Tastes bitter

No artificial flavoring or colors

No THC-free option

Made from 100% organic and natural ingredients

Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score

4.6

CBDC Evaluation Table/Score
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Light Spearmint flavor

No other flavor

Non-THC, Non-detected in drug test

Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score

4.7

CBDC Evaluation Table/Score
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Various delicious flavors to choose from

cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options

Has vegan, organic, and gluten-free ingredients

Free shipping for this particular product within USA

World-class customer service team

Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score

4.4

CBDC Evaluation Table/Score
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60-Day Satisfaction Guarantee

Dropper is a bit shaky

Various strengths

Oil extracted from aerial plant parts of US grown industrial hemp

Sourced from non-GMO industrial hemp grown in the USA through natural farming practices

Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score

4.6

CBDC Evaluation Table/Score
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Customer Service

Type

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Pros Cons

Pure CBD hemp

No other flavors

All natural

A bit pricey compared to competitors

Approximately 100 drops total

Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score

4.4

CBDC Evaluation Table/Score
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Vegan and Gluten free

Does not ship internationally

Has a third-party lab test

Wide variety of CBD strengths and sizes

Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score

3.9

CBDC Evaluation Table/Score
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Pros Cons

Wide variety of flavors

Incomplete information about the product

Lab test results are complete

Does not ship to all international countries

30-day money-back guarantee

Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score

3.7

CBDC Evaluation Table/Score
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Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes

Shipping not specified on website

More flavors to choose from

3rd party lab result is currently not available on website

Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate

Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With Appetite

CBD (cannabidiol) and THC (tetrahydrocannabinol) are cannabinoids naturally present in the resin of the cannabis plant. These chemical substances interact with the cannabinoid receptors found throughout the body(1)

Cannabinoid receptors, namely CB1 and CB2, are part of the endocannabinoid system’s components. 

The endocannabinoid system or ECS is responsible for maintaining homeostasis or balance. It regulates various bodily functions, including(2):

  • Learning and memory
  • Temperature and pain control
  • Inflammatory and immune responses
  • Sleep 
  • Appetite  

Another component of the ECS is the endogenous cannabinoids (endocannabinoids), which are naturally occurring chemical substances that bind to cannabinoid receptors to elicit a response. 

Endocannabinoids may interact with the CB1 receptors in the brain, stimulating appetite and ingestive behaviors(3)

A study from the journal Molecules stated that plant-based cannabinoids (phytocannabinoids) like CBD and THC may mimic the activity of endocannabinoids through the activation of CB1 and CB2 receptors(4)

Although CBD has a low affinity for cannabinoid receptors, the non-psychoactive compound displays a high potency as an antagonist(5)

An antagonist blocks a biological response by binding to and blocking a receptor instead of activating it. 

Recent developments suggest that cannabinoid receptor antagonists like CBD have the potential to manage obesity(6).

A study about obesity and appetite control mentioned that serotonin, a chemical nerve cell that helps regulate body temperature, behavior, and attention, may have a role in appetite suppression(7).

A 2020 study from Frontiers in Behavioral Neuroscience hypothesized that CBD may act at 5-HT1A receptors in the human brain(8)

5-HT1A receptors are a subtype of serotonin receptors that help with body functions like neuromodulation.

Serotonin’s suppressive effects on appetite appear to be driven by 5-HTR2C(9)  (5-hydroxytryptamine receptor 2C), which regulates energy balance, including glucose metabolism and feeding(10).  

Tecott and colleagues observed that mice with insufficient 5-HTR2C had increased appetite and were prone to obesity(11)

Activation of 5-HTR2C by serotonin may also inhibit dopamine release in some regions of the brain(12)

Dopamine, which helps a person feel pleasure, along with serotonin, opioids, and cannabinoids, like CBD and THC, are implicated in the rewarding effects of food(13)

Although CBD does not directly affect dopamine production, the compound may increase the levels of anandamide(14), a fatty acid neurotransmitter, which appears to raise dopamine levels in the brain(15)

CBD’s activity in the endocannabinoid system seems promising. Still, current research does not show CBD’s apparent effect on appetite. 

Until more conclusive studies are done, always consult your doctor before using CBD to lose weight or help with weight gain and improve overall well-being.    

Benefits of Using CBD for Managing One’s Appetite

Existing studies regarding CBD focus on its potential to provide pain relief for certain conditions associated with chronic pain(16). Meanwhile, research about the benefits of CBD on appetite is still lacking. 

However, a study suggests that CBD may promote fat browning, turning fat white cells to brown cells or BAT (brown adipose tissue)(17)

BAT may use regular fat as fuel during activity or exercise(18). The mitochondria in BAT are engines that burn calories to produce heat. 

For this reason, the fat browning process has become a key focus area in research due to its potential to help with obesity(19)

The Molecular and Cellular Biochemistry study suggests that since CBD promotes fat browning, the compound may be a promising therapeutic agent for preventing obesity(20)

Meanwhile, an animal study hypothesized that exposure to CBD may reduce rats’ appetites(21)

Research from Frontiers in Endocrinology stated a close link between metabolic disorders like diabetes and obesity(22)

A randomized controlled trial from Clinical Hemorheology and Microcirculation suggested that CBD may reduce early pancreatic inflammation in type 1 diabetes(23).

Meanwhile, about 30% of parents who administered CBD to their children with epilepsy reported increased appetite(24).   

Existing studies regarding CBD’s potential benefits on appetite are mixed. In addition, most research on other related medical conditions is done on animals. 

Still, researchers who want to explore the benefits of CBD oil in an individual’s appetite may find the studies mentioned useful.  

How to Use CBD Oil for Appetite Management

First-pass metabolism is a metabolic process by which any active compounds pass through the gastrointestinal system and are metabolized by the liver before entering the bloodstream. 

Researchers from the University of Minnesota suggested that high-fat foods may improve CBD absorption into the body(25). Compared to fasting, taking cannabidiol with food may increase the amount of CBD in the body by four times. 

The onset time of CBD via the ingestion route is between 30 and 90 minutes(26)

Meanwhile, the sublingual method relies on the mucous membrane under the tongue to absorb CBD. 

Since this administration route avoids the liver and stomach, its bioavailability is between 6% and 20%(27)

Bioavailability is the extent to which a particular substance becomes entirely available to its intended biological destination. 

CBD via the sublingual route has an onset time of 15 to 30 minutes(28)

Generally, CBD oil and tinctures come with a calibrated dropper. You can use that tool to dispense the oil straight into your mouth. 

What Is the CBD Dosage Optimal for Appetite Management?

The FDA (Food and Drug Administration) does not approve CBD as a supplement to either suppress or increase appetite

However, 23 patients with Dravet syndrome were treated for three months with increasing doses of up to 25 mg of CBD per kilogram of body weight in addition to their usual medication(29).  

Dravet syndrome is a severe and rare form of epilepsy that starts in infancy and causes hard-to-control seizures. 

About 39% of the patients administered with CBD reported a reduction in seizure frequency and experienced changes in appetite(30)

Still, it is best to talk with a healthcare professional experienced in cannabis use to determine the proper CBD dosage for managing one’s appetite. 

How Long Does CBD Take to Help With Appetite Issues?

How long CBD takes to help with appetite problems depends on several factors, including the administration route and body weight

You will feel the effects of CBD via the ingestion route between 30 and 90 minutes. Usually, the compound’s effects will last for 6 to 8 hours(31).

Meanwhile, taking CBD under the tongue has an onset time of 15 to 30 minutes, and the effect of CBD typically lasts for 2 to 4 hours(32).  

How Long Will CBD Help With Appetite Problems

How long CBD will last after it takes effect to help with appetite issues depends on its half-life.

The half-life of a particular drug is the time taken for its plasma concentration to reduce by 50% of its original value. 

CBD’s half-life was reported between 1.4 and 10.9 hours following oromucosal spray use and two to five days after chronic oral administration(33)

Choosing the Best CBD Oil for Appetite Management

Various CBD brands in the market promise to offer high-quality CBD oil (hemp oil) to help with appetite. Below are a few pertinent factors to consider that may help you sort through products to find the right CBD oil for your needs: 

  • CBD Extracts

Full-spectrum CBD oil contains all compounds of the cannabis plant, including CBD and other cannabinoids, essential oils, flavonoids, and terpenes. This CBD variant also has less than 0.3% THC

Flavonoids are active compounds found in cannabis with purported antioxidant, anti-inflammatory, and antiviral actions(34)

Meanwhile, terpenes are the components of essential oils responsible for the aroma of cannabis(35)

Broad-spectrum CBD oil also contains all of the natural compounds of cannabis. However, it is THC-free. Lastly, CBD isolates refer to the type of CBD that contains pure cannabidiol only.

  • Source of Hemp  

Opt for a CBD brand that is transparent with its farming practices. If possible, always opt for gluten-free CBD products or CBD oil from organic hemp.    

Legitimate producers grow hemp in accordance with the programs of the United States Department of Agriculture (USDA), the state, and tribal plans.

  • Extraction Method 

The extraction method is the process where CBD oil is derived from cannabis

Carbon dioxide, ethanol, or solvent extraction is preferred to create a safe CBD product(36). The CBD extract may then be diluted with oils, such as olive oil

  • Types of CBD Products 

Most CBD-derived products available in the market are:

  • Vapes
  • CBD oils and CBD tinctures 
  • Edibles like CBD gummies and capsules
  • Topicals like CBD creams, salves, and lotions

The type of CBD products you choose will depend on your lifestyle, preferences, specific conditions, and expected CBD effects. 

  • Carrier Oils 

After extracting CBD from the hemp plant, CBD manufacturers infuse cannabidiol into a carrier oil. 

The most commonly utilized carrier oils are MCT oil (medium-chain triglycerides oil), coconut oil, and hempseed oil.

Hempseed oil is sufficient in nutrients and fatty acids, although it does not contain CBD(37).  

The Risks and Side Effects of Using CBD for Appetite Issues

Any illness can decrease appetite, leading to weight loss(38). CBD may also cause reduced appetite(39)

Hence, seeking medical advice is necessary before taking CBD. Such a measure helps avoid potential risks for people with eating disorders like anorexia(40) or other medical conditions like colon cancer or chronic liver disease(41)

Other reported side effects of using cannabidiol include drowsiness, low blood pressure, and dry mouth(42)

Is CBD Completely Safe When Used for Appetite Problems?

Aside from potential risks and side effects, another cause for concern is the lack of regulation of CBD products marketed as supplements(43)

The FDA has limited scientific data about CBD’s safety(44). Hence, the agency will constantly update the public as it learns more about the compound.

CBD’s safety profile has been established in numerous ways(45). Still, some knowledge gaps should be closed by further clinical trials for a completely well-tested pharmaceutical compound. 

Legality of CBD

At the federal level, cannabis (sometimes called marijuana) remains a Schedule I substance under the Controlled Substances Act(46)

The United States Drug Enforcement Administration or DEA said that substances listed in the Schedule I drugs category have a high abuse potential with no accepted medical use(47)

As a protective measure, states with medical marijuana laws have a patient registry to protect individuals against arrest for possessing up to a certain amount of cannabis-derived products for personal medicinal use(48)

Colorado permits recreational and medical marijuana use. The local government decriminalized the use of marijuana by passing Amendment 64 to the Colorado Constitution in November 2012(49).

In Indiana, Gov. Eric Holcomb signed Senate Enrolled Act No. 52 into law, allowing distribution and retail sale of “low-THC hemp extract(50)The Farm Bill states that Cannabis sativa L. and other derivatives of cannabis with no more than 0.3% THC content on dry weight are legal under federal law(51).

Product Frequently
Asked Questions

  • How can CBD help with appetite?

    No research directly suggests that CBD helps with human appetite. However, a study suggests that CBD exposure may curb rats’ appetites(52).

  • What evidence or research exists to say that CBD helps with one’s appetite?

    No research exists directly suggesting that CBD helps with an individual’s appetite. However, CBD may attenuate the appetitive effects of THC(53). CB1 antagonists may reduce the desire to eat(54)

    CBD is an antagonist of cannabinoid receptors(55).

  • Is there any evidence that CBD can make appetite worse?

    No evidence suggests that CBD can make appetite worse. However, CBD may reduce one’s appetite(56). Therefore, the compound may not be advisable for people with eating disorders.

  • Will CBD interact with any current medications I may be taking for appetite improvement?

    CBD is not a biologically inert compound. Hence, it may interact with other medications(57)

    For instance, CBD may have an interaction with opioids, which are common cancer treatments.

    Opioids are usually part of pain relief plans for cancer patients(58). However, CBD may increase serum concentrations of opioids(59)

    Aside from this interaction, appetite loss is a common side effect of cancer and its treatments(60).

  • Are there other treatments I should consider alongside CBD to help with appetite problems?

    Peppermint oil may help reduce appetite(61). Still, it is best to talk with a doctor versed in cannabis use before taking CBD simultaneously with other treatments and supplements for appetite issues.

  • Can I fail a drug test if I use CBD for my appetite issues?

    CBD does not induce a psychoactive effect(62). Nevertheless, some CBD products have small amounts of THC that may build up in the body when taken regularly in four to six days(63)

    An increased THC level in the bloodstream may result in a positive drug test.

  • What is the CBD dosage for appetite management? How much should I take?

    There is no standard CBD dosage for appetite. However, about 23 patients with Dravet syndrome were treated for three months with increasing doses of up to 25 mg of CBD per kilogram of body weight. Some also reported changes in appetite(64).

  • Is CBD safe to use to help with my appetite problems?

    CBD has a good safety profile(65). However, more research is warranted to elucidate its long-term safety on appetite issues.

  • Is CBD legal to take for appetite management?

    The legality of CBD varies from state to state. So be aware of your current state laws regarding the use of CBD to help with appetite and other health-related issues.

  • Does the FDA approve CBD?

    The only FDA-approved CBD drug is Epidiolex. Epidiolex is utilized to treat rare and severe epilepsy and seizures associated with tuberous sclerosis complex in children aged one year and older(66).

  • What are the side effects of CBD on appetite?

    CBD may reduce appetite(67). Other side effects of using CBD include drowsiness and low blood pressure(68).


  1. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  2. The Endocannabinoid System: Essential and Mysterious
    https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
  3. Endocannabinoids in the Regulation of Appetite and Body Weight
    https://journals.lww.com/behaviouralpharm/Abstract/2005/09000/Endocannabinoids_in_the_regulation_of_appetite_and.4.aspx
  4. Cancer Initiation, Progression and Resistance: Are Phytocannabinoids from Cannabis sativa L. Promising Compounds?
    https://www.mdpi.com/1420-3049/26/9/2668/htm
  5. The Diverse CB1 and CB2 Receptor Pharmacology of Three Plant Cannabinoids: Δ9-Tetrahydrocannabinol, Cannabidiol and Δ9-Tetrahydrocannabivarin
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
  6. Endocannabinoids in the Regulation of Appetite and Body Weight
    https://journals.lww.com/behaviouralpharm/Abstract/2005/09000/Endocannabinoids_in_the_regulation_of_appetite_and.4.aspx
  7. Obesity and Appetite Control
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415214/
  8. Cannabidiol Acts at 5-HT1A Receptors in the Human Brain: Relevance for Treating Temporal Lobe Epilepsy
    https://www.frontiersin.org/articles/10.3389/fnbeh.2020.611278/full
  9. Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule
    https://academic.oup.com/edrv/article/40/4/1092/5406261
  10. Central 5-HTR2C in the Control of Metabolic Homeostasis
    https://www.frontiersin.org/articles/10.3389/fendo.2021.694204/full
  11. Eating Disorder and Epilepsy in Mice Lacking 5-HT2c Serotonin Receptors
    https://pubmed.ncbi.nlm.nih.gov/7700379/
  12. Administration of Cannabis Causes Alterations in Monoamine Oxidase B and Serotonin Receptor 2c Gene Expressions in Wistar Rats
    https://publisher.medfak.ni.ac.rs/AFMN_1/2021/1-2021/full%20text/4Administration%20of%20Cannabis%20O.Dosumu.pdf
  13. Reward, Dopamine and the Control of Food Intake: Implications for Obesity
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124340/
  14. Cannabinoid Regulation of Fear and Anxiety: an Update
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486906/
  15. Anandamide Administration Alone and After Inhibition of Fatty Acid Amide Hydrolase (FAAH) Increases Dopamine Levels in the Nucleus Accumbens Shell in Rats
    https://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2006.03880.x
  16. A Balanced Approach for Cannabidiol Use in Chronic Pain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204604/
  17. Cannabidiol Promotes Browning in 3T3-L1 Adipocytes
    https://pubmed.ncbi.nlm.nih.gov/27067870/
  18. What Is Brown Fat? How Is It Different From Other Body Fat?
    https://www.mayoclinic.org/healthy-lifestyle/weight-loss/expert-answers/brown-fat/faq-20058388
  19. The Browning of White Fat
    https://www.endocrinology.org/endocrinologist/126-winter17/features/the-browning-of-white-fat/
  20. Cannabidiol Promotes Browning in 3T3-L1 Adipocytes
    https://pubmed.ncbi.nlm.nih.gov/27067870/
  21. Cannabinol and Cannabidiol Exert Opposing Effects on Rat Feeding Patterns
    https://pubmed.ncbi.nlm.nih.gov/22543671/
  22. LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920035/
  23. Experimental Cannabidiol Treatment Reduces Early Pancreatic Inflammation in Type 1 Diabetes
    https://pubmed.ncbi.nlm.nih.gov/27767974/
  24. Perceived Efficacy of Cannabidiol-Enriched Cannabis Extracts for Treatment of Pediatric Epilepsy: A Potential Role for Infantile Spasms and Lennox-Gastaut Syndrome
    https://pubmed.ncbi.nlm.nih.gov/25935511/
  25. High-Fat Foods Can Increase Oral Cannabidiol Absorption Into the Body
    https://www.sciencedaily.com/releases/2019/08/190813130426.htm
  26. Healing With CBD, page 191.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  27. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  28. Ibid.
  29. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  30. Ibid.
  31. Healing With CBD, page 191.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  32. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  33. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01365/full
  34. Flavonoids in Cannabis sativa: Biosynthesis, Bioactivities, and Biotechnology
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931196/
  35. The Cannabis Terpenes
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763918/
  36. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  37. Hemp Seed Oil Properties
    https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
  38. Appetite – Decreased
    https://www.mountsinai.org/health-library/symptoms/appetite-decreased
  39. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  40. Anorexia Nervosa
    https://www.mayoclinic.org/diseases-conditions/anorexia-nervosa/symptoms-causes/syc-20353591
  41. Appetite – Decreased
    https://www.mountsinai.org/health-library/symptoms/appetite-decreased
  42. CBD: What You Need to Know Before You Try
    https://www.cedars-sinai.org/blog/cbd-safe.html
  43. Ibid.
  44. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
    https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
  45. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  46. State Medical Cannabis Laws
    https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx
  47. Drug Scheduling
    https://www.dea.gov/drug-information/drug-scheduling
  48. State Medical Cannabis Laws
    https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx
  49. Legal Marijuana Use in Colorado
    https://cannabis.colorado.gov/legal-marijuana-use-in-colorado
  50. Senate Enrolled Act No. 52
    https://medicalmarijuana.procon.org/wp-content/uploads/sites/37/indiana-sb52.pdf
  51. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  52. Cannabinol and Cannabidiol Exert Opposing Effects on Rat Feeding Patterns
    https://pubmed.ncbi.nlm.nih.gov/22543671/
  53. Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906701/
  54. Ibid.
  55. The Diverse CB1 and CB2 Receptor Pharmacology of Three Plant Cannabinoids: Δ9-Tetrahydrocannabinol, Cannabidiol and Δ9-Tetrahydrocannabivarin
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
  56. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  57. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  58. Opioids for Cancer Pain
    https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/pain/opioid-pain-medicines-for-cancer-pain.html
  59. Medical Cannabis: Adverse Effects and Drug Interactions, page 11.
    https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  60. Loss of Appetite
    https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/eating-problems/poor-appetite.html
  61. Effect of Acute Peppermint Oil Administration on Gastric Sensorimotor Function and Nutrient Tolerance in Health
    https://pubmed.ncbi.nlm.nih.gov/23489975/
  62. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  63. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  64. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  65. Ibid.
  66. FDA Approves New Indication for Drug Containing an Active Ingredient Derived from Cannabis to Treat Seizures in Rare Genetic Disease
    https://www.fda.gov/news-events/press-announcements/fda-approves-new-indication-drug-containing-active-ingredient-derived-cannabis-treat-seizures-rare
  67. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  68. CBD: What You Need to Know Before You Try
    https://www.cedars-sinai.org/blog/cbd-safe.html

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