Best CBD Oil for Cerebral Palsy
While scientists are still looking for a potential cure for cerebral palsy, some treatments and remedies may help address its symptoms. Find out how CBD oil may help manage some of the symptoms and complications associated with CP.
Best CBD Oil for Cerebral Palsy 2024
- Spruce 750mg Lab Grade CBD Oil Editor's Pick
- NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil Best Organic
- Spruce 2400mg Lab Grade CBD Oil Editor's Pick
- Avida Full Spectrum CBD Oil Tincture 500mg Best Seller
- cbdMD CBD Oil Tincture Natural 1500mg Best Natural Alternative
- CBDistillery THC Free CBD Oil Tinctures Best THC-Free
- cbdMD CBD Oil Tincture Natural 750mg Best Customer Rated
- NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil Best Starter
- Hemp Bombs 750mg CBD Oil Best Flavor Range
- Royal CBD Full Spectrum CBD Oil Most Transparent
Compare the best CBD Oil for Cerebral Palsy in 2022
Best CBD Oil for Cerebral Palsy
1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Mid-strength |
No other flavors |
Natural peppermint flavor |
|
Made from 100% organic and natural ingredients |
Overview
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Pure CBD hemp |
No other flavors |
All natural |
|
Approximately 300 drops total |
Overview
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Extra Strength |
Tastes bitter |
No artificial flavoring or colors |
No THC-free option |
Made from 100% organic and natural ingredients |
Overview
The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.
4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Light Spearmint flavor |
No other flavor |
Non-THC, Non-detected in drug test |
Overview
Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.
5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Various delicious flavors to choose from |
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options |
Has vegan, organic, and gluten-free ingredients |
|
Free shipping for this particular product within USA |
|
World-class customer service team |
Overview
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
60-Day Satisfaction Guarantee |
Dropper is a bit shaky |
Various strengths |
|
Oil extracted from aerial plant parts of US grown industrial hemp |
|
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices |
Overview
CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.
7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Pure CBD hemp |
No other flavors |
All natural |
A bit pricey compared to competitors |
Approximately 100 drops total |
Overview
This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.
8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Vegan and Gluten free |
Does not ship internationally |
Has a third-party lab test |
|
Wide variety of CBD strengths and sizes |
Overview
A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.
9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Wide variety of flavors |
Incomplete information about the product |
Lab test results are complete |
Does not ship to all international countries |
30-day money-back guarantee |
Overview
Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.
10. Royal CBD Full Spectrum CBD Oil
cbdc overall score
3.7
CBDC Evaluation Table/Score
Pros | Cons |
---|---|
Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes |
Shipping not specified on website |
More flavors to choose from |
3rd party lab result is currently not available on website |
Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate |
Overview
Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.
While scientists are still looking for a potential cure for cerebral palsy, some treatments and remedies may help address its symptoms. Find out how CBD oil may help manage some of the symptoms and complications associated with CP.
How CBD Helps With Cerebral Palsy
Cannabidiol or CBD is a cannabis plant compound that works through the body’s endocannabinoid system (ECS)(1).
The ECS consists of essential components like the CB1 and CB2 cannabinoid receptors. CB1 and CB2 receptors are responsible for regulating many bodily functions like learning, sleep, pain control, eating, and inflammatory and immune responses(2).
When activated, these receptors modulate essential functions in the central nervous system (CNS)(3).
In particular, there is a high density of cannabinoid receptors in specific parts of the brain like the cerebellum and basal ganglia that control motor function(4).
One study stated that CB1 expression may affect spasticity and motor function among individuals with neurodegenerative disorders(5).
While the study mentioned above was focused mainly on rats, the ECS is found in all mammals, including humans(6). ECS-related studies in animals may be helpful as a reference for human studies.
Spasticity is characterized by muscle spasms, muscle stiffness, and involuntary contractions. These symptoms are usually associated with neurological conditions like cerebral palsy, stroke, multiple sclerosis, and traumatic brain injury(7).
Another study, published in Therapeutic Advances in Neurological Disorders, mentioned that CB1 receptors are the primary targets in the CNS pathways to deliver antispastic effects(8).
Seizures and spasms are cerebral palsy symptoms similar to those of epilepsy. Epileptic seizures are common in patients with cerebral palsy and tend to have an earlier onset in children with cerebral palsy(9).
To date, Epidiolex is the only cannabis-based CBD treatment approved by the FDA to treat seizures associated with epilepsy.
Benefits and Uses of CBD for Cerebral Palsy
Research shows around 23-46% of children with CP experience sleeping difficulties, possibly caused by immobility and pain(10).
The effects of medical cannabis on pediatric patients with complex motor disorders were examined by researchers led by pediatric neurologist Lubov Blumkin in 2018(11).
The researchers performed a clinical trial using two CBD products with a CBD-to-THC ratio of 20:1 and 6:1 on children with CP.
The study showed that the CBD products may help manage sleep difficulties, pain severity, spasticity, and dystonia (involuntary contraction of muscles) associated with CP.
Additionally, CBD’s interaction with the CB1 and CB2 receptors, including the 5-HT1A neuroreceptor, may have the potential to help manage depression and anxiety in humans(12).
The 5-HT1A serotonin receptor is associated with the mediation of anxiety and depression-like behaviors in people.
In another study in The Permanente Journal in 2019, researchers suggested CBD may help address insomnia and reduce anxiety scores among adults(13).
Results from a placebo-controlled study suggested that CBD may have the potential to help manage chronic pain in patients with rheumatoid arthritis(14).
CBD Dosage for Cerebral Palsy
Currently, there is no FDA-approved CBD dosage guide for cerebral palsy. However, people may take CBD starting with a lower dose(15).
Exercise, diet, genetics, health conditions, and stress levels may affect CBD dosage(16).
The FDA has not currently approved CBD as a treatment for CP. If you know someone with CP or has symptoms indicative of CP, recommend them for a scheduled appointment with a doctor first.
How to Take CBD for Cerebral Palsy
Several methods of taking CBD oil to help manage symptoms of CP and improve quality of life include:
- Sublingual administration – This method delivers CBD oil directly into the bloodstream, bypassing the digestive tract.
CBD oil tinctures delivered using droppers or oromucosal sprays are standard methods to administer CBD sublingually or under the tongue.
- Oral administration – CBD administered orally passes through the digestive tract before being carried into the bloodstream.
Some products taken orally include CBD capsules and edibles. Examples of edibles are gummies and candies.
- Topical application – CBD products like creams, balms, or lotions are applied to the skin.
- Vaping – Vaping involves administering CBD by inhalation. This method may be considered one of the fastest ways to deliver CBD into the body(17).
If you consider vaping as a method to take CBD, be aware that vaping has potential health risks related to lung disease(18).
Individuals with health issues must consult their doctor before vaping or smoking CBD.
How Long Does CBD Oil Take to Help With Cerebral Palsy?
There is currently no specific study on onset times of CBD for cerebral palsy.
One reference mentioned that onset times for CBD oral ingestion may take around 30 to 90 minutes.
Generally, CBD administered through a sublingual application, topicals, and transdermal administration may take 15 to 30 minutes to take effect. Meanwhile, the onset time of CBD by inhalation is 2 to 15 minutes(19).
How Long Will CBD Oil Help With Cerebral Palsy?
To date, there is insufficient scientific data on the duration of CBD’s effects on cerebral palsy.
A review published in Frontiers of Pharmacology in 2018 stated that CBD oromucosal sprays applied at 5mg to 20mg doses may have a half-life of 1.4 and 10.9 hours(20).
Half-life is the period a drug takes to reduce its quantity or concentration within the body by 50%.
Side Effects and Risks of Using CBD for Cerebral Palsy
Side effects of CBD use include appetite loss, drowsiness, dry mouth, diarrhea, and fatigue(21).
Check the CBD product’s label for a grapefruit warning. A grapefruit warning means CBD may interact with other drugs, preventing them from metabolizing and getting absorbed by the body.
The warning comes from the effects of grapefruit juice on other substances. Grapefruit juice blocks the CYP3A4 enzymes needed for drug metabolization(22).
Unmetabolized drugs may remain in the body longer. Too much drug in the system can lead to more side effects.
Choosing the Best CBD Oil for Cerebral Palsy
There are several considerations to determine the best CBD oil to help with cerebral palsy, such as extraction methods and CBD product types.
Cannabis oil can be extracted from the cannabis plant using carbon dioxide (CO2), ethanol, or hydrocarbon extraction methods.
The extracted CBD oil may be classified as full-spectrum, broad-spectrum, or isolates.
Full-spectrum CBD oil contains all the cannabinoids and compounds from the cannabis plant, including tetrahydrocannabinol (THC), terpenes, and flavonoids.
Terpenes give off an aromatic effect, while flavonoids have antioxidant properties.
Combining these compounds creates an “entourage effect,” where the effects of cannabinoids and other compounds are greater than the sum of the benefits of each contributing part(23).
Broad-spectrum CBD oils have similar contents as full-spectrum CBD oil except for THC. On the other hand, isolates only contain pure CBD without other cannabinoids or compounds.
Consider broad-spectrum or isolates if you prefer CBD products without the psychoactive effects of THC.
When choosing a CBD product, most consumers prefer those that are non-GMO, gluten-free, or made from organic hemp.
Legality of CBD
When the 2018 Farm Bill was enacted, it removed hemp-based CBD products containing less than 0.3% THC from the Drug Enforcement Administration’s controlled substances list. The law also legalized the cultivation of industrial hemp.
CBD products containing more than 0.3% THC are still prohibited under federal law(24).
The legal use of CBD oil and medical marijuana may vary among states. Review your state’s laws and check your CBD product’s THC content to determine whether using CBD is legal in your area.
An important disclaimer on CBD products is that you should not use them for treating any illness or disease. Consult your physician about your current medical condition before purchasing CBD products from a website, pharmacy, or dispensary.
A Close Look at Cerebral Palsy
Cerebral palsy is a group of health disorders commonly associated with childhood motor disability. CP affects movement, balance, and posture.
Some symptoms of cerebral palsy include(25):
- Spasticity (muscle stiffness or reflex exaggeration)
- Jerky involuntary movements or tremors
- Ataxia (lack of muscle coordination or balance)
- Muscle tone variations (too stiff or too floppy)
- Walking difficulties
Spastic cerebral palsy is the most common form of cerebral palsy, affecting around 80% of individuals with CP. A person with spastic CP may have stiff muscles, increased muscle tone (hypertonia), and awkward movements(26).
Other complications associated with CP include muscle tissue shortening (contracture), malnutrition, mental health conditions, sleep disorders, chronic pain, and oral health issues(27).
One study stated that several chronic conditions may be associated with CP among middle-aged adults. These conditions include diabetes, osteoporosis, stroke, hypertension, and rheumatoid arthritis(28).
Another study mentioned that adults with CP may have a high risk of developing anxiety and depression(29).
Doctors have a variety of methods to diagnose individuals who may have CP, such as physical tests, laboratory tests, magnetic resonance imaging (MRI), and electroencephalogram (EEG).
The Centers for Disease Control and Prevention states that there is currently no cure for CP. However, various treatments are available that may improve the lives of people experiencing CP(30).
Current medications for CP symptoms include muscle relaxants like diazepam (Valium) or tizanidine (Zanaflex) and nerve injections like Botox. Other treatment options include physiotherapy, speech therapy, and orthopedic surgeries(31).
Product Frequently
Asked Questions
-
How can CBD help with cerebral palsy?
CBD helps by interacting with the body’s endocannabinoid system(32). The ECS contains cannabinoid receptors that help regulate learning, sleep, pain control, appetite, and inflammatory and immune responses(33).
The CB1 cannabinoid receptor may affect spasticity and motor function among individuals with neurodegenerative disorders(34). Cerebral palsy affects spasticity and motor functions.
-
What evidence or research exists to say that CBD helps with cerebral palsy?
A 2018 study suggests that CBD products may help manage sleep difficulties, pain severity, spasticity, and involuntary muscle contraction in individuals with a complex motor disorder(35). These symptoms are associated with CP.
Another study showed that CBD may help manage chronic pain in patients with rheumatoid arthritis(36). Rheumatoid arthritis is a chronic condition associated with CP.
-
Is there any evidence that CBD can make cerebral palsy worse?
Currently, there is no direct evidence showing CBD worsens cerebral palsy.
However, CBD may cause side effects, including appetite loss, drowsiness, dry mouth, diarrhea, and fatigue(37).
-
Will CBD interact with any current medication I may be taking for cerebral palsy?
Look for the grapefruit warning on CBD product labels. This warning means CBD may interact with other drugs, preventing them from metabolizing and getting absorbed by the body.
Ask your doctor before deciding to take CBD, especially if you are currently taking other medications for cerebral palsy.
-
Are there other treatments I should consider alongside CBD to help with cerebral palsy?
Inform your physician first if you plan to take CBD together with other treatment options.
Your physician may recommend some treatment methods like physiotherapy, occupational therapy, or speech therapy(38).
-
Can I fail a drug test if I use CBD for cerebral palsy?
CBD products that contain less than 0.3% THC do not usually lead to a failed drug test. However, your THC levels may increase with frequent and prolonged CBD oil use(39).
-
What is the dosage for cerebral palsy?
The FDA has not approved any specific dosage for cerebral palsy.
However, some studies suggest 1 to 50 milligrams of CBD per kilogram of body weight per day may be a viable dosage range(40).
- page 103 of Healing With CBD
https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view - The endocannabinoid system: Essential and mysterious
https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569 - Endocannabinoids in nervous system health and disease: the big picture in a nutshell
https://doi.org/10.1098/rstb.2012.0313 - Temporal changes of CB1 cannabinoid receptor in the basal ganglia as a possible structure-specific plasticity process in 6-OHDA lesioned rats
https://doi.org/10.1371/journal.pone.0076874 - Ibid.
- The Endocannabinoid System of Animals
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770351/ - Spasticity
https://www.hopkinsmedicine.org/health/conditions-and-diseases/spasticity - Evidence for the efficacy and effectiveness of THC-CBD oromucosal spray in symptom management of patients with spasticity due to multiple sclerosis
https://doi.org/10.1177%2F1756285615612659 - Cerebral palsy and epilepsy
https://pubmed.ncbi.nlm.nih.gov/21446143/ - Sleep and Children with Cerebral Palsy: A Review of Current Evidence and Environmental Non-Pharmacological Interventions
https://doi.org/10.3390/children2010078 - Medical Cannabis for Pediatric Moderate to Severe Complex Motor Disorders
http://dx.doi.org/10.1177/0883073818773028 - Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis sativa
https://doi.org/10.2174/1871527313666140612114838 - Cannabidiol in Anxiety and Sleep: A Large Case Series
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/ - Efficacy and safety of cannabidiol followed by an open label add-on of tetrahydrocannabinol for the treatment of chronic pain in patients with rheumatoid arthritis or ankylosing spondylitis: protocol for a multicentre, randomised, placebo-controlled study
https://doi.org/10.1136/bmjopen-2018-028197 - CBD dosing
https://www.projectcbd.org/guidance/cbd-dosing - Ibid.
- Best way to take CBD
https://www.projectcbd.org/guidance/best-way-take-cbd - Can vaping damage your lungs? What we do (and don’t) know
https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734 - page 190-195 of Healing With CBD
https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view - A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
https://doi.org/10.3389/fphar.2018.01365 - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 - Grapefruit Juice and Some Drugs Don’t Mix
https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix - The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324885/ - CBD & THC: Myths and misconceptions
https://www.projectcbd.org/cbd-101/cbd-misconceptions - Cerebral palsy: Symptoms and causes
https://www.mayoclinic.org/diseases-conditions/cerebral-palsy/symptoms-causes/syc-20353999 - What is Cerebral Palsy?
https://www.cdc.gov/ncbddd/cp/facts.html - Cerebral palsy: Symptoms and causes
https://www.mayoclinic.org/diseases-conditions/cerebral-palsy/symptoms-causes/syc-20353999 - Multimorbidity in Middle-Aged Adults with Cerebral Palsy
https://pubmed.ncbi.nlm.nih.gov/28065772/ - Risk of Depression and Anxiety in Adults With Cerebral Palsy
https://doi.org/10.1001/jamaneurol.2018.4147 - What is Cerebral Palsy?
https://www.cdc.gov/ncbddd/cp/facts.html - Cerebral palsy: Diagnosis and treatment
https://www.mayoclinic.org/diseases-conditions/cerebral-palsy/diagnosis-treatment/drc-20354005 - page 103 of Healing With CBD
https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view - The endocannabinoid system: Essential and mysterious
https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569 - Temporal changes of CB1 cannabinoid receptor in the basal ganglia as a possible structure-specific plasticity process in 6-OHDA lesioned rats
https://doi.org/10.1371/journal.pone.0076874 - Medical Cannabis for Pediatric Moderate to Severe Complex Motor Disorders
http://dx.doi.org/10.1177/0883073818773028 - Efficacy and safety of cannabidiol followed by an open label add-on of tetrahydrocannabinol for the treatment of chronic pain in patients with rheumatoid arthritis or ankylosing spondylitis: protocol for a multicentre, randomised, placebo-controlled study
https://doi.org/10.1136/bmjopen-2018-028197 - What are the benefits of CBD — and is it safe to use?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 - Cerebral palsy: Diagnosis and treatment
https://www.mayoclinic.org/diseases-conditions/cerebral-palsy/diagnosis-treatment/drc-20354005 - Can You Take CBD and Pass a Drug Test?
https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/ - A systematic review of cannabidiol dosing in clinical populations
https://doi.org/10.1111/bcp.14038