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Best CBD Oil for Stress

Want to buy CBD for stress relief but uncertain about which product is the best? Choose from this list of high-quality CBD products for stress, and see which one suits your needs.

Rating
Highlights

Editor's Pick

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best Organic

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Editor's Pick

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Seller

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. made using only CBD sourced from medical hemp
  2. available in many flavours
  3. safe for daily use

Best THC-Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best Starter

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Compare the Best CBD Oil for Stress in 2021

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5

Best CBD Oil for Stress

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

Benefits of CBD for Stress

Stress is the body’s natural reaction when changes occur(1). When you are faced with danger, stress signals the body to prepare to face a threat or flee for safety.

As a result, your pulse quickens, breathing becomes faster, muscles become tense, and the brain uses more oxygen and increases survival activity.

Meanwhile, in non-life-threatening situations, stress can motivate you, such as when taking tests or undergoing job interviews.

However, prolonged, unchecked, and unmanaged stress may be detrimental to your health(2). It can contribute to various medical conditions, like high blood pressure, heart disease, obesity, and diabetes.

CBD for Stress

Cannabidiol (CBD), a phytocompound found in cannabis plants, is becoming known for its potential therapeutic benefits in various health issues. A 2018 study of cannabidiol users from Cannabis and Cannabinoid Research showed that CBD may have health benefits that may help with pain, anxiety, depression, and sleep disorders(3).

A 2019 study from The Permanente Journal measured sleep and anxiety scores in 72 adults(4). Results revealed that CBD may hold benefits for anxiety-related disorders.

According to a 2015 review, animal studies showed that CBD may reduce anxiety behaviors linked to multiple disorders(5). These include panic disorder (PD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).

The review also noted that these findings were backed by human experimental results, which suggested CBD’s minimal sedative effects and excellent safety profile.

Unlike tetrahydrocannabinol (THC), cannabidiol (CBD) is non-addictive and does not make users feel high(6). This characteristic makes CBD a viable option for individuals dealing with anxiety.

A 2018 study from the Brazilian Journal of Psychiatry investigated the acute effects of different CBD doses and placebo in healthy volunteers performing a simulated public speaking test(7). Results showed that 300 to 600mg of CBD significantly reduced anxiety symptoms in 57 adult males.

Another study published in Neuropsychopharmacology examined CBD’s effects on anxiety induced by simulated public speaking(8). Results revealed that CBD may significantly reduce anxiety, cognitive impairment, and discomfort in people with social anxiety disorders

A 2019 study also examined the effects of repeated cannabidiol treatment in teenagers with social anxiety disorders(9). Results indicated that CBD may be a useful option to treat social anxiety.

CBD for Post-Traumatic Stress Disorder

Approximately 3.5% of adults in the United States (US) get PTSD every year, while 1 in 11 people may be diagnosed with PTSD in their lifetime(10).

Post-traumatic stress disorder (PTSD) is a mental health condition that may occur in individuals who have experienced traumatic events, such as a natural disaster, a severe injury, a terrorist act, war or combat, or sexual violence. 

CBD may have therapeutic benefits for PTSD. A review of various animal studies showed that cannabidiol may facilitate the extinction of aversive memories and block their reconsolidation(11). Researchers linked these effects to CBD’s interaction with the endocannabinoid system.

The ECS regulates biological functions, including mood and pain perception(12).

A 2013 study provided the first evidence that CBD may enhance extinction learning consolidation in humans(13). Extinction learning is defined as the gradual decrease in response to a conditioned stimulus, frequently linked to PTSD therapy.

The participants received 32mg of CBD, and results showed successful conditioning, extinction, and recall in the subjects.

Consistent with animal studies’ findings, these results indicated that CBD may be beneficial when used alongside exposure therapy. This type of treatment is a psychological approach developed to help individuals face their fears.

Moreover, a 2019 case study published in the Journal of Alternative and Complementary Medicine examined the effects of oral CBD administration on the symptoms of PTSD in 11 adult patients at an outpatient psychiatry clinic(14). Results showed that CBD may decrease PTSD-related symptoms.

How CBD Helps With Stress

CBD’s potential benefits for stress, anxiety, depression, and other medical conditions may be attributed to the compound’s interaction with the endocannabinoid system (ECS). 

The ECS is a complex system that maintains homeostasis or balance in different biological functions(15). These include mood, pain perception, and immune response.

The ECS also consists of two main types of cannabinoid receptors: CB1 receptors and CB2 receptors. Located on cells throughout the body, both receptors interact with cannabinoids or natural compounds in the body.

CB1 receptors can be found in the brain and central nervous system, liver, lungs, and kidney(16). They regulate bodily functions, such as memory processing, appetite, pain sensation, mood, and sleep.

Meanwhile, CB2 receptors lie in cells within the immune system and its associated structures(17). Once activated, these receptors stimulate a response that helps fight inflammation.

Research also showed that CBD may produce anxiolytic effects by indirectly activating other receptors, like 5-HT1A serotonin receptors(18).

Serotonin is a neurotransmitter that results in feelings of wellness and happiness(19)

A 2005 study also indicated that cannabidiol may inhibit serotonin’s reuptake in the brain, making serotonin more available for the body(20). With better regulation of serotonin, CBD may help stabilize mood and reduce anxiety.

How Soon Can CBD’s Effects Be Felt?

CBD’s potential benefits for stress may be felt immediately or delayed depending on several factors. These include the CBD administration method, your body weight, metabolism, the CBD potency, and product quality.

CBD oil tinctures facilitate direct absorption of CBD into the bloodstream(21). Effects may be evident within 15 to 45 minutes.

CBD oil vapes also allow CBD to enter the bloodstream through the lungs. Effects may be felt within 20 minutes.

Moreover, you can easily take CBD edibles for stress. However, unlike tinctures and vapes, CBD edibles may take longer to work as CBD needs to pass through the digestive system. 

The effects of CBD edibles, like gummies, may kick in within 30 to 60 minutes(22).

The duration of CBD’s potential therapeutic effects for stress may depend on the form of CBD used.

While CBD tinctures may provide immediate relief, effects may last for four to six hours only. 

Meanwhile, CBD edibles’ effects may last for over six hours(23). For CBD vapes, results may last for 30 minutes to two hours at most.

Other factors, like CBD dosage, metabolism, the frequency of use, and product quality, affect how long CBD may help with stress.

Possible Side effects of Using CBD for Stress

Despite CBD’s potential therapeutic benefits, the compound may also induce some side effects. According to Mayo Clinic, these include(24):

  • Diarrhea
  • Dry mouth
  • Drowsiness
  • Fatigue
  • Tiredness
  • Reduced appetite
  • Changes in weight

CBD may also interact with other drugs, like blood thinners. 

According to a 2011 review, other side effects of CBD include the decreased activities of p-glycoprotein and other drug transporters, inhibition of hepatic drug metabolism, and reduced fertilization capacity(25).

You must consult a healthcare professional knowledgeable about CBD use for proper guidance.

How to Choose the Best CBD for Stress

You can buy various forms of CBD for stress, including CBD tinctures, edibles, capsules, and vapes. However, to pick the best CBD oil products for stress, you must observe the following steps:

  1. To ensure proper CBD use, consult healthcare professionals, especially when purchasing CBD products for the first time or taking other medications.
  2. Check whether the CBD product uses non-GMO, organic hemp. CBD brands, like CBDistillery, Nuleaf Naturals, and Charlotte’s Web, use GMO-free hemp plants grown from Colorado.
  3. Choose quality products that use CO2 extraction methods to maximize the benefits of hemp extracts.
  4. Verify whether the product undergoes third-party lab testing. The certificate of analysis (COA), often available on the brand’s website, should show the product’s actual CBD content and the absence of pesticides, heavy metals, residual solvents, and other harmful contaminants.
  5. Compare product label claims with the COA. Third-party lab results of high-quality products with great value for money show accurate or higher CBD content than their product label claims.
  6. Select CBD brands with certifications, memberships to hemp organizations, or accreditation from the Better Business Bureau (BBB). The highest quality CBD companies often meet these criteria as they demonstrate strict compliance with industry standards, transparency, excellent customer service, and ethical business practices.
  7. Research on state laws regarding cannabis use to legally buy CBD products for stress online or from different CBD retail stores. Most stores have an age requirement of 18 or 21 years old.
  8. Pick CBD brands that do not have unsupported health claims, provide disclaimers on their websites, and offer a full money-back guarantee.
  9. Know the difference between full-spectrum CBD, broad-spectrum CBD, and CBD isolates.

Full-spectrum hemp extracts have a complete range of phytocannabinoids or naturally occurring compounds in cannabis plants, including CBD, THC, terpenes, flavonoids, fatty acids, essential oils, and other minerals.

Terpenes provide cannabis plants’ unique aroma, while flavonoids provide vivid colors to most plants.

These compounds produce the entourage effect, which implies that they provide more benefits when combined than when they are used as isolated elements(26). Thus, full-spectrum CBD oil suits users who want to maximize all the cannabis compounds’ benefits.

Meanwhile, broad-spectrum CBD also contains all compounds in cannabis plants, except THC. Consumers who want THC-free products may use broad-spectrum CBD and CBD isolates.

CBD isolates are pure CBD extracted in isolation from all other compounds. These CBD products allow you to maximize the benefits of CBD.

How to Use CBD for Stress

With the growing research on CBD’s potential health benefits for various medical conditions, CBD attracts several consumers. Thus, the CBD industry produces different types of CBD oil products to match each user’s needs and preferences.

Common CBD products for stress include CBD tinctures, CBD capsules, CBD edibles, CBD topicals, and CBD vapes.

CBD Tinctures

CBD tincture is the most common CBD product format. It usually has carrier oils, like medium-chain triglyceride or MCT oil, peppermint oil, and hemp oil.

You can conveniently apply CBD tinctures sublingually or directly under the tongue to allow faster absorption of CBD directly into the bloodstream(27).

Moreover, you can let the desired quantity of drops stay under your tongue for 60 to 120 seconds before swallowing(28). CBD tinctures’ effects may be experienced within 15 to 45 minutes.

CBD tinctures are also arguably the best delivery method for self-titration because you can adjust on a drop-by-drop or milligram-by-milligram basis if needed(29).

Reliable CBD tinctures have labeled droppers for exact dosing. However, it helps to know that the standard dropper size is 1 milliliter, and there are about 20 drops in 1 dropper/milliliter(30).

Generally, the effects of CBD tinctures may last for four to six hours. Still, results depend on different factors, like the CBD administration method, your body weight, metabolism, and the CBD potency.

One drawback of CBD tinctures is their unpleasant, earthy taste. Fortunately, other CBD brands offer CBD tinctures in different flavors. However, be cautious of artificial flavors or additives.

You can also add CBD tinctures to your food, smoothie, or coffee.

Furthermore, CBD tinctures may be used with CBD lotions and creams and applied transdermally for site-specific pain relief.

An animal study showed that CBD topicals may reduce inflammation and arthritis-pain related symptoms without evident side effects(31).

CBD Capsules

Another convenient way to take CBD oil for stress is through CBD capsules. However, CBD capsules may take longer to work than oral CBD drops as they have to pass through the digestive system(32).

Moreover, dosing is tricky because of the delayed onset of effect (one to two hours), unknown effects of stomach acids, recent meals, and other factors(33).

Thus, CBD capsules may not be suitable for those needing immediate relief from stress and related symptoms.

CBD Edibles

Those who do not want the earthy, grassy taste of pure CBD hemp extract can take CBD edibles for stress, like CBD gummies and CBD chocolate bars. Several CBD brands offer these CBD edibles in various flavors.

CBD gummies and CBD chocolate bars suit those who find it hard to swallow pills and prefer a discreet way to take CBD for stress. However, CBD edibles may take 30 to 60 minutes to work(34). CBD must be digested first before entering into the bloodstream, where it interacts with the endocannabinoid system.

You should seek professional help first before taking CBD products for stress to ensure safety.

CBD Topicals

You can also apply topical CBD products for stress, like CBD creams, CBD lotions, CBD salves, and CBD bath bombs.

As CBD topicals are absorbed into the skin’s surface, you may apply a more significant amount of CBD to your skin. However, start at low doses to observe how your skin reacts to CBD.

Once you see positive changes after several days of use, you may gradually increase the dosage.

Effects of topical CBD products may be felt after an hour or two and may last for six hours or even several days.

However, results may vary based on the CBD administration method, your body weight, metabolism, CBD potency, and product quality.

You can also check the product labels or the brand’s official website to see whether products use nanotechnology, encapsulation, or CBD micellization.

These terms indicate that the product’s solution can carry CBD through the dermal layers instead of staying on the skin’s surface.

According to research from the International Journal of Molecular Sciences, nanotechnology may help increase drug bioavailability, permit a site-specific targeted delivery, and reduce toxic side effects(35).

Still, it is best to consult a healthcare provider knowledgeable about CBD to determine the right dosage based on your needs and preferences.

CBD Vapes

CBD oil vapes may also provide fast results as CBD enters the bloodstream through the lungs without going through the digestive system.

However, effects may last for 30 minutes to an hour or two only. It is also hard to determine precisely how much CBD is in each draw.

While CBD oil vape products often indicate the CBD amount per inhale, the amount may vary per person.

Furthermore, the Food and Drug Administration (FDA), Centers for Disease Control and Prevention, and other state and local health departments have conducted investigations regarding a national outbreak of e-cigarette or vaping product use-associated lung injury (EVALI)(36).

As of February 2020, there were 2,807 hospitalized EVALI reported cases or deaths. Thus, the CDC and FDA do not recommend the use of vapes.

CBD Dosage for Stress

Current evidence shows that a CBD dosage of up to 1,500 mg/day is well tolerated in humans(37).

However, the only FDA-approved CBD product is Epidiolex, which is used to treat rare cases of epilepsy in children(38). The drug’s recommended starting dosage is 2.5mg of CBD per kilogram of body weight, taken twice daily. 

After a week, users can increase the dosage to 5mg of CBD per kilogram of body weight maintenance dosage, taken twice daily(39). Other than this, there is no official recommended CBD dosage for stress.

However, the general rule is to start low and slow. You can begin taking at least 5 mg of CBD and increase the dosage once you achieve your desired results.

You should also consult a healthcare professional knowledgeable about CBD use to determine the right CBD dosage based on your needs and preferences.

Legality of CBD

Due to the 2018 Farm Bill, hemp-derived CBD products containing 0.3% or less THC became legal at the federal level(40).

Tetrahydrocannabinol is a psychoactive compound in cannabis plants that produces a euphoric feeling among users. While hemp-derived CBD products are no longer under the Controlled Substances Act (CSA), marijuana remains a Schedule 1 controlled drug(41).

Schedule 1 drugs refer to substances that are not allowed for medical use and have a high potential for abuse(42).

According to the Food and Drug Administration, marijuana has a high risk of abuse because of THC’s psychoactive effects(43). The 2018 Farm Bill also preserves the FDA’s right to regulate products with cannabis or cannabis-derived compounds.

According to the FDA, products with CBD or THC should not be sold legally as dietary supplements(44). Currently, the agency has approved one cannabis-derived drug product: Epidiolex (cannabidiol), and three synthetic cannabis-related drug products: Marinol (dronabinol), Syndros (dronabinol), and Cesamet (nabilone) only(45).

Epidiolex is a purified form of CBD derived from cannabis. The product is approved to help treat seizures linked to Lennox-Gastaut syndrome and Dravet syndrome, two rare cases of epilepsy in children.

Meanwhile, Marinol and Syndros are approved to treat anorexia associated with weight loss in patients with acquired immunodeficiency syndrome (AIDS).

Cesamet is approved for the alleviation of nausea linked to cancer chemotherapy.

As these are the only FDA-approved cannabis products, consumers should research state laws and purchase CBD in areas that allow recreational use or medical use of marijuana.

Product Frequently
Asked Questions

  • How can CBD help with stress?

    CBD’s potential benefits for stress may be associated with the compound’s interaction with the endocannabinoid system. This system helps maintain balance in various bodily functions, such as mood, pain perception, and immune response(46).

  • What evidence or research exists to say that CBD helps with stress?

    Current research suggested that CBD may produce anti-anxiety effects that may reduce the response to stressful environmental factors(47).

  • Is there any evidence that CBD can make stress worse?

    While research on CBD for stress remains inconclusive, no studies showed that CBD may worsen stress. Current evidence indicated that CBD may have anxiolytic (anxiety-reducing) effects(48).

  • Will CBD interact with any current medication I may be taking for stress?

    CBD may interact with other drugs you are taking for stress and alter how the body breaks down these medications(49). Thus, you should seek medical advice to use CBD safely.

  • Are there other treatments I should consider alongside CBD to help with stress?

    Other treatments for stress include prescription medications, antidepressants, and aromatherapy. You should seek medical advice on CBD use to avoid adverse effects from drug interactions.

  • Can I fail a drug test if I use CBD for stress?

    CBD is a non-psychoactive compound, so it does not give you a euphoric high(50). However, there are CBD products with small levels of THC, the psychoactive compound in cannabis plants. Frequent usage of these products may give you a false-positive drug test result.

  • What is the CBD dosage for stress?

    There is no official dosage available for CBD for stress. However, the general rule is to start taking CBD at lower doses, around 5mg of CBD. Then, you can gradually increase the dosage once you see positive effects after several days of use.

  • Is CBD good for anxiety?

    Current evidence suggests that CBD may have anxiolytic effects, making it a potential treatment for anxiety-related disorders(51).

  • Which CBD brand is best for anxiety?

    The best CBD oil for anxiety usually comes from brands that use organic industrial hemp, adopt the CO2 extraction process, have CBD content accurate with the product label, and possess certifications or accreditations from the BBB or hemp organizations.


  1. National Institute of Mental Health. 5 Things You Should Know About Stress. Retrieved from https://www.nimh.nih.gov/health/publications/stress/index.shtml
  2. Mayo Clinic. Stress symptoms: Effects on your body and behavior. Retrieved from https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress-symptoms/art-20050987 
  3. Corroon, J., & Phillips, J. A. (2018). A Cross-Sectional Study of Cannabidiol Users. Cannabis and cannabinoid research, 3(1), 152–161. doi.org/10.1089/can.2018.0006. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/#:~:text=Results%3A%20Almost%2062%25%20of%20CBD,reported%20%E2%80%9Cnot%20very%20well.%E2%80%9D 
  4. Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal, 23, 18–041. doi.org/10.7812/TPP/18-041. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/ 
  5. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics: the journal of the American Society for Experimental NeuroTherapeutics, 12(4), 825–836. doi.org/10.1007/s13311-015-0387-1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/ 
  6. National Institute on Drug Abuse. (2015, Jul. 20). Researching Marijuana for Therapeutic Purposes: The Potential Promise of Cannabidiol (CBD). Retrieved from https://archives.drugabuse.gov/about-nida/noras-blog/2015/07/researching-marijuana-therapeutic-purposes-potential-promise-cannabidiol-cbd 
  7. Linares, I. M., Zuardi, A. W., Pereira, L. C., Queiroz, R. H., Mechoulam, R., Guimarães, F. S., & Crippa, J. A. (2019). Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Revista brasileira de psiquiatria (Sao Paulo, Brazil: 1999), 41(1), 9–14. doi.org/10.1590/1516-4446-2017-0015. https://pubmed.ncbi.nlm.nih.gov/30328956/ 
  8. Bergamaschi, M. M., Queiroz, R. H., Chagas, M. H., de Oliveira, D. C., De Martinis, B. S., Kapczinski, F., Quevedo, J., Roesler, R., Schröder, N., Nardi, A. E., Martín-Santos, R., Hallak, J. E., Zuardi, A. W., & Crippa, J. A. (2011). Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 36(6), 1219–1226. doi.org/10.1038/npp.2011.6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079847/ 
  9. Masataka N. (2019). Anxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders. Frontiers in psychology, 10, 2466. doi.org/10.3389/fpsyg.2019.02466. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856203/ 
  10. American Psychiatric Association. What Is Posttraumatic Stress Disorder? Retrieved from https://www.psychiatry.org/patients-families/ptsd/what-is-ptsd#:~:text=Posttraumatic%20stress%20disorder%20(PTSD)%20is,sexual%20violence%20or%20serious%20injury 
  11. Bitencourt, R. M., & Takahashi, R. N. (2018). Cannabidiol as a Therapeutic Alternative for Post-traumatic Stress Disorder: From Bench Research to Confirmation in Human Trials. Frontiers in neuroscience, 12, 502. doi.org/10.3389/fnins.2018.00502. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066583/ 
  12. Education Collaboration Hope. (2017, Apr. 18). A Look at the Endocannabinoid System’s CB1 and CB2 Receptors. Retrieved from https://echoconnection.org/look-endocannabinoid-systems-cb1-cb2-receptors/
  13. Das, R. K., Kamboj, S. K., Ramadas, M., Yogan, K., Gupta, V., Redman, E., Curran, H. V., & Morgan, C. J. (2013). Cannabidiol enhances consolidation of explicit fear extinction in humans. Psychopharmacology, 226(4), 781–792. doi.org/10.1007/s00213-012-2955-y. https://pubmed.ncbi.nlm.nih.gov/23307069/#:~:text=No%20acute%20effects%20of%20CBD,based%20therapies%20for%20anxiety%20disorders
  14. Elms, L., Shannon, S., Hughes, S., & Lewis, N. (2019). Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series. Journal of alternative and complementary medicine (New York, N.Y.), 25(4), 392–397. doi.org/10.1089/acm.2018.0437. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482919/ 
  15. Education Collaboration Hope. (2017, Apr. 18). Op Cit.
  16. Ibid. 
  17. Ibid. 
  18. Linares, I. M. (2019). Op Cit.
  19. Education Collaboration Hope. (2017, Mar. 29). What Are the Differences Between CBD and THC? Retrieved from https://echoconnection.org/differences-cbd-thc/ 
  20. Russo, E. B., Burnett, A., Hall, B., & Parker, K. K. (2005). Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochemical research, 30(8), 1037–1043. doi.org/10.1007/s11064-005-6978-1. https://pubmed.ncbi.nlm.nih.gov/16258853/ 
  21. Arthritis Foundation. CBD for Arthritis Pain: What You Should Know. Retrieved from https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain 
  22. Borodovsky, J. T., Crosier, B. S., Lee, D. C., Sargent, J. D., & Budney, A. J. (2016). Smoking, vaping, eating: Is legalization impacting the way people use cannabis? The International journal on drug policy, 36, 141–147. doi.org/10.1016/j.drugpo.2016.02.022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010515/ 
  23. Ibid. 
  24. Bauer, B. A. (2018, Dec. 20). What are the benefits of CBD — and is it safe to use? Retrieved from https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 
  25. Bergamaschi, M. M., Queiroz, R. H., Zuardi, A. W., & Crippa, J. A. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current drug safety, 6(4), 237–249. doi.org/10.2174/157488611798280924. https://pubmed.ncbi.nlm.nih.gov/22129319/ 
  26. Russo E. B. (2019). The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain. Frontiers in plant science, 9, 1969. doi.org/10.3389/fpls.2018.01969. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/ 
  27. Arthritis Foundation. CBD for Arthritis Pain. Op Cit. 
  28. Ibid. 
  29. Konieczny, E., & Wilson, L. (2018). Healing with CBD: how cannabidiol can transform your health without the high. Berkeley, California: Ulysses Press. 
  30. Ibid. 
  31. Hammell, D. C., Zhang, L. P., Ma, F., Abshire, S. M., McIlwrath, S. L., Stinchcomb, A. L., & Westlund, K. N. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. European journal of pain (London, England), 20(6), 936–948. doi.org/10.1002/ejp.818. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/ 
  32. Arthritis Foundation. CBD for Arthritis Pain. Op Cit. 
  33. Ibid. 
  34. Borodovsky, J. T. (2016). Op Cit. 
  35. Conte, R., Marturano, V., Peluso, G., Calarco, A., & Cerruti, P. (2017). Recent Advances in Nanoparticle-Mediated Delivery of Anti-Inflammatory Phytocompounds. International journal of molecular sciences, 18(4), 709. doi.org/10.3390/ijms18040709. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412295/ 
  36. Centers for Disease Control and Prevention. (2020, Feb. 25). Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products. Retrieved from https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html 
  37. Bergamaschi, M. M. (2011). Op Cit. 
  38. U.S. Food and Drug Administration. Epidiolex (cannabidiol) oral solution. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210365lbl.pdf 
  39. Ibid. 
  40. U.S. Food and Drug Administration. (2020, Oct. 1). FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). Retrieved from https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd 
  41. Ibid. 
  42. Drug Enforcement Administration. Drug Scheduling. Retrieved from https://www.dea.gov/drug-scheduling#:~:text=for%20the%20schedule
  43. U.S. Food and Drug Administration. (2020, Oct. 1). FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). Op Cit.
  44. Ibid. 
  45. U.S Food and Drug Administration. (2020, Oct. 1). FDA and Cannabis: Research and Drug Approval Process. Retrieved from https://www.fda.gov/news-events/public-health-focus/fda-and-cannabis-research-and-drug-approval-process 
  46. Education Collaboration Hope. (2017, Apr. 18). Op Cit. 
  47. Linares, I. M. (2019). Op Cit.
  48. Ibid.
  49. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154. doi.org/10.1089/can.2016.0034. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/ 
  50. Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S., & Corsi, L. (2018). Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer. BioMed research international, 2018, 1691428. doi.org/10.1155/2018/1691428. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304621/ 
  51. Shannon, S. (2019). Op Cit.
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