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Best CBD Oil for Skin Disorders

Interested in trying CBD oil to help alleviate the symptoms of skin disorders? We reviewed the top CBD products to help you choose the best CBD oil for your skin problems.

Editor's Pick

Spruce 750mg Lab Grade CBD Oil

Best Organic

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Editor's Pick

Spruce 2400mg Lab Grade CBD Oil

Best Seller

Avida Full Spectrum CBD Oil Tincture 500mg

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg

Best THC-Free

CBDistillery THC Free CBD Oil Tinctures

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

Best Starter

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

Hemp Bombs 750mg CBD Oil

Best Allergy Friendly

Sunsoil CBD Oil Drops, Chocolate Mint Flavor

Rating
4.8 out of 5

5.0 out of 5

5.0 out of 5

4.6 out of 5

4.7 out of 5

4.4 out of 5

4.4 out of 5

4.6 out of 5

3.9 out of 5

3.6 out of 5
Highlights
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)
  1. made using only CBD sourced from medical hemp
  2. available in many flavours
  3. safe for daily use
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription
  1. Tastes great
  2. Uses hemp grown organically
  3. Laboratory tests done by a third party

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Compare the Best CBD Oil for Skin Disorders in 2021

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Sunsoil CBD Oil Drops, Chocolate Mint Flavor
3.6 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

3.5 out of 5

5.0 out of 5

Best CBD Oil for Skin Disorders

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pro's
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Con's
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pro's
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Con's
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pro's
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Con's
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pro's
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Con's
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pro's
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Con's
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pro's
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Con's
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pro's
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Con's
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pro's
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Con's
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pro's
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Con's
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Sunsoil CBD Oil Drops, Chocolate Mint Flavor
cbdc overall score
3.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.  Product selection is limited.
 The company tests its products thrice before making them available to the public.  The company uses lipid extraction methods.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Pro's
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.
 The company tests its products thrice before making them available to the public.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Con's
 Product selection is limited.
 The company uses lipid extraction methods.
Overview

The flavor profile is refreshingly sweet, and it balances well with the higher CBD concentration. Promotes the absorption of CBD into your blood circulation.

How CBD Helps With Skin Disorders

A study showed that topical cannabidiol (CBD) application may help improve the skin conditions of individuals with inflammatory skin disorders, like psoriasis and atopic dermatitis(1).

CBD works by interacting with the body’s endocannabinoid system (ECS) to help provide therapeutic relief for chronic skin problems(2).

The ECS maintains the body’s homeostasis or internal balance. It helps regulate our daily bodily functions, including our immune system, metabolism, and anti-inflammatory response(3).

The ECS has receptors that are spread throughout the body. These receptors may be stimulated or triggered by endocannabinoids (cannabinoids produced by the body)(4).

Phytocannabinoids (plant-based cannabinoids), such as CBD and tetrahydrocannabinol (THC), may also influence ECS receptors to trigger specific responses. 

The CB1 and CB2 receptors are the two main receptors of the ECS. These receptors are present in most body tissues(5).

CB1 receptors are abundantly found in the central nervous system. These receptors influence appetite, memory processing, sleep patterns, pain sensation, and motor function(6).

Meanwhile, CB2 receptors are more commonly found in the immune system. When CB2 receptors are activated, they may trigger anti-inflammatory effects and help relieve the symptoms of inflammation-related health issues(7).

Studies also noted the presence of the ECS and its receptors in the skin(8).

Moreover, findings showed that the ECS is involved in maintaining skin balance and forming the skin barrier, which may help treat skin health conditions(9).

CB1 and CB2 receptors are abundant in normal, healthy skin(10). These receptors are found in keratinocytes, sebaceous or oil glands, nerve fibers, and other parts of the skin.

Keratinocytes are the main type of skin cells found in the skin’s epidermis or outer layer(11).

Findings linked the dysregulation or abnormal expression of keratinocytes to chronic inflammatory skin diseases, like psoriasis, eczema, and allergic contact dermatitis(12).

Studies suggested that CBD may influence and trigger the ECS receptors in keratinocytes to prevent the excessive increase of these skin cells and help alleviate the symptoms of skin disorders(13).

Influencing and activating the skin’s CB2 receptors may also help stimulate sebum or oil production to combat dry skin(14).

Triggering the CB1 and CB2 receptors may also aid in inhibiting inflammation linked to dermatitis and help suppress skin tumors’ growth(15).

Benefits of CBD for Skin Disorders

Available studies suggested that the use of CBD oil and topical CBD products may help provide therapeutic relief for different symptoms of severe and common skin conditions.

Research also showed that CBD had high antioxidant properties(16). Antioxidants may help address several skin issues, such as melasma (a skin pigmentation disorder), skin aging, and psoriasis(17).

Findings also suggested that CBD had anti-bacterial benefits due to Cannabis sativa plants’ natural ability to help control bacterial infections(18).

CBD may also be used to help enhance the anti-bacterial effects of some antibiotics, which may help in treating skin problems and skin infections(19).

Psoriasis

Psoriasis is a common chronic skin disease characterized by patches of thick, raised lesions or plaques covered by silvery scales(20). Other symptoms of psoriasis include itchiness, dry skin, and swollen joints.

According to a study, keratinocytes (epidermal skin cells) may be a potential trigger for psoriasis(21).

The abnormal proliferation or increase of keratinocytes contributes to an accelerated skin cell turnover, which may then cause the formation of psoriatic plaques(22).

A 2020 study published in the journal Molecules suggested that CBD and THC may influence the ECS to help suppress the proliferation of keratinocytes(23).

The researchers also noted that CBD and THC may also help modulate the inflammatory component in keratinocytes and reduce skin inflammation(24).

Contact Dermatitis and Itchiness

The study in Molecules also suggested that CBD’s anti-inflammatory properties may also help suppress the inflammatory reaction caused by allergic contact dermatitis(25).

Allergic contact dermatitis is a skin condition marked by itchy rashes due to hypersensitivity to certain substances or allergens(26).

The researchers observed that CBD reduced inflammation from allergic contact dermatitis without being toxic to the cells(27).

A 2017 study published in the Journal of the American Academy of Dermatology showed that applying CBD cream helped eliminate pruritus or severe itching in 8 out of 21 study participants(28).

Dr. Robert Dellavalle, an author of the study and an associate professor at the University of Colorado School of Medicine, stated that the treatment of itch may be the most promising role for cannabinoids(29).

Acne and Dandruff

CBD oil may also help with bad skin and acne problems. Researchers noted that CBD may help regulate sebum or oil secretion(30). Excessive sebum production is one factor that increases the likelihood and severity of acne(31).

The combination of CBD’s sebostatic (sebum control) effect, anti-inflammatory properties, and anti-bacterial activity makes it a promising anti-acne agent(32).

Several skincare products containing CBD are currently available on the market, touting CBD’s alleged anti-acne and anti-inflammatory benefits to help calm the skin.

Findings indicated that influencing the CB2 receptors to inhibit sebum production may also help address seborrhea or seborrheic dermatitis, which causes redness and scaly skin patches(33)

Seborrheic dermatitis commonly affects the scalp and is also referred to as dandruff(34).

Epidermolysis Bullosa

A separate study noted that sublingual (under the tongue) intake of pharmaceutical-grade CBD helped improve the quality of life of patients suffering from epidermolysis bullosa(35).

Epidermolysis bullosa is a group of rare diseases characterized by fragile, blistering, painful, and irritated skin(36).

All three epidermolysis bullosa patients that took CBD sublingually for the study reported better pain scores, less itching, and reduced overall analgesic drug intake(37).

Another small observational study involving topical CBD use for epidermolysis bullosa showed similar positive results(38).

The three patients that used topical CBD reported pain improvement, less blistering, and faster wound healing. One of the patients also stopped taking opioid analgesics for pain(39).

Although CBD holds promise as a treatment for skin disorders, findings regarding the benefits of CBD remain inconclusive. Researchers continue to call for more studies to be conducted on CBD.

Possible Risks of Using CBD for Skin Disorders

A study on the therapeutic effects of topical CBD administration showed that CBD is safe and effective in improving the condition and quality of life of patients with certain skin disorders(40).

The researchers did not observe any allergic reactions or adverse effects on the study participants during the treatment duration(41).

However, other studies noted possible risks when using CBD, particularly when it is ingested or smoked.

The possible side effects of using CBD oil include the following(42):

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness or fatigue
  • Weight loss or weight gain

CBD may also adversely interact with other drugs, particularly blood thinners(43). CBD use may also affect the efficacy of some eczema medications.

Tacrolimus is an eczema ointment prescribed for patients whose eczema problems have not responded to other medications(44).

Using CBD together with tacrolimus may decrease the rate at which the body metabolizes the drug, possibly increasing the levels of tacrolimus in the body(45).

A high amount of tacrolimus in the body is ill-advised. Tacrolimus use has been linked to skin cancer and lymphoma cases, although there is no definitive proof that using tacrolimus causes cancer(46).

Another eczema medication that may interact with CBD is prednisone, an oral steroid prescribed for severe eczema flare-ups(47). Taking prednisone may affect how fast CBD gets broken down by the liver(48).

If you are taking other medications for your skin disorder, it is highly advised to consult your dermatologist before using oral or topical CBD.

Moreover, it is important to remember that CBD has not been approved by the US Food and Drug Administration (FDA) as a treatment for any health issue(49).

As of January 2021, the epilepsy medication Epidiolex is the only FDA-approved drug with CBD as a major component(50).

The FDA continues to warn consumers that extremely high CBD doses are linked to potential liver injury(51).

It is recommended to talk to a certified medical doctor or dermatologist familiar with CBD usage before taking CBD to help ensure optimal product effectiveness and your overall wellness.

How Soon Can CBD’s Effects Be Felt

You may start feeling the effects of CBD anywhere between a few minutes to a few hours, depending on the method of administration.

Different delivery methods, CBD potencies, and product formulations may affect the bioavailability of CBD.

Bioavailability is the speed and amount at which a product or drug gets absorbed into the bloodstream.

Inhaling or vaporizing CBD is generally regarded as the fastest delivery method for CBD. This method allows CBD to enter your bloodstream in as fast as 30 seconds(52).

The effects of vaping CBD may last from one to four hours, depending on the amount and potency of the CBD product. The fast onset (start of effect) and short efficacy duration make CBD inhalation advisable for acute issues, like nausea or acute pain(53).

However, take note that studies have associated vaping with cases of lung issues or respiratory complications(54).

While safety investigations are still ongoing, the FDA and the US Centers for Disease Control and Prevention also caution against vaping, particularly CBD products with THC(55).

Topical CBD administration is recommended for addressing skin problems and joint pain issues(56).

Online anecdotal accounts note that the effects of topical CBD products may take one or two hours to be felt.

The sublingual delivery method is also shown to be effective for some skin disorders(57).

Sublingual CBD administration requires letting the CBD oil sit underneath the tongue for 60 seconds or more before swallowing(58).

Users may start to feel the effects of CBD within 15 to 60 minutes, with the results possibly lasting between six and eight hours(59).

How to Use CBD for Skin Disorders

The rule of thumb for first-time CBD users is to start with a low CBD dosage and concentration. You may slowly increase the dosing until you achieve your desired effects.

More severe skin disorders may require a more potent CBD product, particularly CBD topicals. 

Always remember that CBD is not an approved FDA medication for any skin disorder. As such, there is no official dosage guideline.

It is highly advised to talk to a dermatologist knowledgeable on CBD use for a more accurate dosage recommendation.

Researchers suggested that topical CBD administration may be ideal for addressing localized symptoms of skin conditions, arthritis, and neuropathic pain(60).

A recent study published in October 2020 indicated that a hydrophilic gel consisting of propylene glycol was highly effective for CBD absorption and retention through the skin(61).

Other topical products, such as CBD lotions, CBD creams, CBD salves, and CBD balms, are also recommended for addressing skin disorders.

CBD skin care products, such as face creams and facial oils, are gaining popularity as companies and brands promote the purported anti-bacterial, anti-acne, and anti-inflammatory benefits of CBD oil.

When using topical CBD, it is recommended to apply the cream or gel liberally to help ensure that the affected area gets enough product(62).

Additionally, make sure to clean the affected area before applying topical CBD(63). Bacteria and other invisible contaminants on the skin may affect the product’s effectiveness.

How to Choose CBD Products for Skin Disorder

Full-spectrum CBD products have a complete range of phytocannabinoids naturally found in cannabis plants, including THC, terpenes, flavonoids, and fatty acids.

Terpenes (aromatic plant compounds) may offer added relaxation and therapeutic benefits(64). Meanwhile, flavonoids may provide additional antioxidant and anti-inflammatory relief(65).

Full-spectrum CBD produces an entourage effect, in which all the cannabinoids and compounds work together to enhance each other’s therapeutic effects.

Broad-spectrum CBD contains almost the full range of phytocannabinoids and other compounds, with the exception of the psychoactive (mind-altering) THC.

Meanwhile, CBD isolates contain pure CBD only.

People with skin disorders may benefit most from full-spectrum CBD, as studies showed that the combination of THC and CBD may help improve skin diseases(66).

Here are other tips when choosing high-quality CBD products for skin disorders:

  • Choose brands that are transparent about their hemp sources, extraction process, and third-party laboratory testing results.
  • Always make sure that the CBD products have certificates of analysis (COAs) and are tested for CBD potency and harmful contaminants, like pesticides and solvents.
  • Look for active ingredients offering additional moisturizing and hydrating benefits that may help reduce dryness and itchiness.
  • Essential oils and plant oils may help improve skin conditions. For instance, coconut oil has anti-bacterial properties, good moisturizing effects, and properties that help with eczema(67).
  • Aloe vera and omega-3 are also excellent skincare ingredients that may help improve skin elasticity and reverse the signs of skin aging(68).

Legality of CBD

The passage of the 2018 Farm Bill or Agriculture Improvement Act of 2018 legalized industrial hemp and hemp-derived products, including CBD oil, on a federal level in the USA(69).

The 2018 Farm Bill defined industrial hemp as Cannabis sativa plants that have less than 0.3% THC on a dry weight basis(70).

Any Cannabis sativa plant or product derivative with THC levels exceeding 0.3% is recognized as marijuana. Thus, it is still prohibited in most parts of the US.

Medical marijuana and THC-rich CBD products are available to patients with qualifying medical conditions, such as Parkinson’s disease or epilepsy, under some states’ medical cannabis programs.

The 2018 Farm Bill permits the cultivation, processing, handling, and selling of hemp plants and hemp derivatives, such as CBD products(71).

The bill also removed industrial hemp and CBD from the Schedule I drugs category(72). Schedule I drugs are substances with no approved medical use and a high possibility for abuse(73).

While CBD products are no longer restricted substances, the FDA still cautions consumers on buying and using CBD oil.

The FDA has approved one CBD-based medication (Epidiolex) only for treating seizures due to rare forms of epilepsy(74).

Moreover, the sale of any food products and beverages, including animal feed, with CBD additives are restricted under FDA regulations(75).

CBD use is legal on the federal level, though states may still impose their own rules and restrictions on the purchase and sale of CBD within their jurisdiction.

Some states, like South Dakota, continue to consider all forms of industrial hemp and CBD products as illegal substances(76).

There are also states, like Washington, that abide by the FDA’s regulations and restrict the sale of food and drinks infused with CBD(77).

CBD users who plan to travel and take their CBD oil with them are advised to read up on their destination state’s CBD laws to help avoid legal complications.

Product Frequently
Asked Questions

  • How can CBD help with skin disorders?

    Studies suggested that CBD interacts with and influences the body’s ECS, aiding in the regulation of daily bodily functions(78).

    Findings also showed that the ECS helps maintain skin homeostasis or balance and affects skin barrier formation and repair(79).

  • What evidence or research exists to say that CBD helps with skin disorders?

    A 2019 study published in the journal La Clinica Terapeutica investigated the therapeutic effects of THC-free CBD ointment on patients with inflammatory skin disorders and resulting scars(80).

    The researchers noted that applying topical CBD daily for three months helped improve the quality of life of patients with psoriasis and eczema(81).

  • Is there any evidence that CBD can make skin disorders worse?

    While more research is warranted on the effects of CBD on skin disorders, available findings showed that skin toxicity and other adverse events due to topical CBD application are sparse(82).

    CBD may induce some side effects, such as dry skin, itching, or hives, though these side effects were mostly due to inhaled or ingested CBD products rather than topical and transdermal CBD(83).

  • Will CBD interact with any current medication I may be taking for a skin disorder?

    CBD may interact with other medications for skin disorders, particularly those for eczema.

    Prednisone is an oral steroid that may be prescribed to help control severe cases of eczema inflammation or flare-ups(84). The drug may affect how quickly CBD is broken down by the liver(85).

    CBD may also interact with tacrolimus and reduce how fast the body breaks down the drug, thus raising tacrolimus levels in the body(86). Tacrolimus is an ointment medication also used to treat eczema(87).

  • Are there any other treatments I should consider alongside CBD to help with skin disorders?

    You may consider using pimecrolimus, a calcineurin inhibitor similar to tacrolimus that helps control eczema by affecting the immune system(88).

    Biologics (drugs made from or using living organisms), like dupilumab, may also help with severe atopic dermatitis or eczema(89).

    Consult your dermatologist before using any medication alongside CBD to avoid possible adverse interactions.

  • Can I fail a drug test if I use CBD for skin disorders?

    High doses and frequent ingestion of full-spectrum CBD products with trace amounts of THC may cause a false-positive drug test result.

    However, using topical CBD products, such as salves or lotions, may help you avoid failing a drug test.

    A small study found that participants received blood and urine tests negative for THC after extensive application of topical THC-rich salves(90).

  • What is the recommended amount of CBD to use for a skin disorder?

    When using CBD, the general rule is to start with a low dosage and potency, then increase the dosage as necessary based on its effects. At present, there are still no official CBD dosage recommendations or guidelines for skin disorders.

    You may start with a microdose of 0.5mg to 20mg of CBD per dose each day or a standard dosage of 10mg to 100mg of CBD per dose daily(91). A standard amount is usually recommended for inflammatory conditions and chronic pain.

  • Who can purchase CBD oil or CBD hemp products?

    States may impose restrictions on who can buy CBD products based on age and product type. For instance, New York requires consumers to be at least 21 years old to purchase inhalable or vape CBD and hemp products(92).

    Some states have no age restrictions for buying CBD, such as Colorado(93).

    CBD oil and CBD hemp products are legal on the federal level. They are commercially available in retail stores, supermarkets, and pharmacies in states that recognize the legality of CBD.

  • What is the best CBD oil for the skin?

    Full-spectrum CBD may be the best CBD oil for skin, as it contains a wide range of other phytocannabinoids that work together to enhance each other’s effectiveness for maximum therapeutic benefits.

    Check the ingredients before buying CBD oil to make sure you get the most out of the product. If possible, go for CBD oils that also contain other moisturizing ingredients to help soothe your skin.

    Shea butter, argan oil, and jojoba oil are good moisturizers that also possess anti-inflammatory properties(94).


  1. Palmieri, B., Laurino, C., & Vadalà, M. (2019). A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars. La Clinica terapeutica, 170(2), e93–e99. https://doi.org/10.7417/CT.2019.2116 
  2. Ibid.
  3. ECHO. (2017, April 18). A Look at the Endocannabinoid System’s CB1 and CB2 Receptors. Retrieved from https://echoconnection.org/look-endocannabinoid-systems-cb1-cb2-receptors/ 
  4. Ibid.
  5. Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends in pharmacological sciences, 30(8), 411–420. https://doi.org/10.1016/j.tips.2009.05.004 
  6. ECHO. (2017, April 18). Op. cit.
  7. Ibid.
  8. Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). Op. cit.
  9. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System. Molecules (Basel, Switzerland), 24(5), 918. https://doi.org/10.3390/molecules24050918 
  10. Scheau, C., Badarau, I. A., Mihai, L. G., Scheau, A. E., Costache, D. O., Constantin, C., Calina, D., Caruntu, C., Costache, R. S., & Caruntu, A. (2020). Cannabinoids in the Pathophysiology of Skin Inflammation. Molecules (Basel, Switzerland), 25(3), 652. https://doi.org/10.3390/molecules25030652
  11. Benhadou, F., Mintoff, D., & Del Marmol, V. (2019). Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?. Dermatology (Basel, Switzerland), 235(2), 91–100. https://doi.org/10.1159/000495291 https://www.karger.com/Article/Fulltext/495291 
  12. Albanesi, C., Scarponi, C., Giustizieri, M. L., & Girolomoni, G. (2005). Keratinocytes in inflammatory skin diseases. Current drug targets. Inflammation and allergy, 4(3), 329–334. https://doi.org/10.2174/1568010054022033 
  13. Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). Op. cit.
  14. Ibid.
  15. Ibid.
  16. Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland), 9(1), 21. https://doi.org/10.3390/antiox9010021
  17. Addor F. (2017). Antioxidants in dermatology. Anais brasileiros de dermatologia, 92(3), 356–362. https://doi.org/10.1590/abd1806-4841.20175697
  18. Kosgodage, U. S., Matewele, P., Awamaria, B., Kraev, I., Warde, P., Mastroianni, G., Nunn, A. V., Guy, G. W., Bell, J. D., Inal, J. M., & Lange, S. (2019). Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles. Frontiers in cellular and infection microbiology, 9, 324. https://doi.org/10.3389/fcimb.2019.00324
  19. Ibid.
  20. Mayo Clinic. (2020, May 2). Psoriasis. Retrieved from https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840
  21. Benhadou, F., Mintoff, D., & Del Marmol, V. (2019). Op. cit.
  22. Ibid.
  23. Scheau, C., Badarau, I. A., Mihai, L. G., Scheau, et. al. (2020). Op. cit.
  24. Ibid.
  25. Ibid.
  26. Mayo Clinic. (2020, June 19). Contact dermatitis. Retrieved from https://www.mayoclinic.org/diseases-conditions/contact-dermatitis/symptoms-causes/syc-20352742 
  27. Scheau, C., Badarau, I. A., Mihai, L. G., Scheau, et. al. (2020). Op. cit.
  28. University of Colorado Anschutz Medical Campus. (2017, April 18). Cannabinoids may soothe certain skin diseases, say researchers: Anti-inflammatory properties may be the key. ScienceDaily. Retrieved January 3, 2021 from www.sciencedaily.com/releases/2017/04/170418094315.htm 
  29. Ibid.
  30. Scheau, C., Badarau, I. A., Mihai, L. G., Scheau, et. al. (2020). Op. cit.
  31. Mayo Clinic. (2020, Sept, 12). Acne. Retrieved from https://www.mayoclinic.org/diseases-conditions/acne/symptoms-causes/syc-20368047 
  32. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478. https://doi.org/10.3390/molecules23102478 
  33. Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). Op. cit.
  34. Mayo Clinic. (2020, April 7). Seborrheic dermatitis. Retrieved from https://www.mayoclinic.org/diseases-conditions/seborrheic-dermatitis/symptoms-causes/syc-20352710
  35. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Op. cit.
  36. Mayo Clinic. (2020, July 29). Epidermolysis bullosa. Retrieved from https://www.mayoclinic.org/diseases-conditions/epidermolysis-bullosa/symptoms-causes/syc-20361062
  37. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Op. cit.
  38. Ibid.
  39. Ibid.
  40. Palmieri, B., Laurino, C., & Vadalà, M. (2019). Op. cit.
  41. Ibid.
  42. Bauer, B. A. (2018, Dec. 20). What are the benefits of CBD — and is it safe to use? Retrieved from https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700 
  43. Ibid.
  44. Medline Plus. (2016, Feb. 15). Tacrolimus Topical. Retrieved from https://medlineplus.gov/druginfo/meds/a602020.html 
  45. MedlinePlus. (2020, Aug. 31). Cannabidiol (CBD). Retrieved from https://medlineplus.gov/druginfo/natural/1439.html
  46. Medline Plus. (2016, Feb. 15). Op. cit.
  47. National Eczema Association. Prescription Oral – Immunosuppresants. Retrieved from https://nationaleczema.org/eczema/treatment/immunosuppressants/ 
  48. MedlinePlus. (2020, Aug. 31). Op. cit.
  49. U.S. Food and Drug Administration. (2020, Oct. 1). FDA regulation of cannabis and cannabis-derived products, including cannabidiol (CBD). https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd 
  50. U.S. Food and Drug Administration. (2018, March 27). FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms
  51. U.S. Food and Drug Administration. (2020, March 3). What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD. Retrieved from https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis 
  52. Gill, L. L. (2018, Aug. 26). How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?. Consumer Reports. Retrieved from https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  53. Devitt-Lee, A. What is the best way to take CBD? Project CBD. Retrieved from https://www.projectcbd.org/how-to/use-cbd-and-cannabis 
  54. Stanbrook M. B. (2019). Vaping-associated lung illnesses highlight risks to all users of electronic cigarettes. CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne, 191(48), E1319–E1320. https://doi.org/10.1503/cmaj.191503 
  55. U.S. Food & Drug Administration. (2020, April 13). Lung Injuries Associated with Use of Vaping Products. Retrieved from https://www.fda.gov/news-events/public-health-focus/lung-injuries-associated-use-vaping-products 
  56. Devitt-Lee, A. What is the best way to take CBD? Op. cit.
  57. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Op. cit.
  58. Devitt-Lee, A. What is the best way to take CBD? Op. cit.
  59. Ibid.
  60. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Op. cit.
  61. Casiraghi, A., Musazzi, U. M., Centin, G., Franzè, S., & Minghetti, P. (2020). Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process. Pharmaceuticals (Basel, Switzerland), 13(11), 337. https://doi.org/10.3390/ph13110337
  62. Bayle, A. (2018, June 29). CBD for the Skin – Topical Use. Hemppedia. Retrieved from https://hemppedia.org/cbd-oil-skin/ 
  63. Ibid.
  64. Ferber, S.G., Namdar, D., Hen-Shoval, D., Eger, G., Koltai, H., Shoval, G., Shbiro, L., Weller, A. (2020). The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324885/
  65. Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: an overview. Journal of nutritional science, 5, e47. https://doi.org/10.1017/jns.2016.41
  66. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Op. cit.
  67. Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International journal of molecular sciences, 19(1), 70. https://doi.org/10.3390/ijms19010070
  68. AlRasheed, M., Hammad, L., Altaweel, A., Assiri, A., Bin Ajlan, A., Almugbel, R., Aldukhail, S., Abanmy, N., Shazly, G. (2020). Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study. Journal of advanced Biomedical and Pharmaceutical Sciences, 3(2), 60-64. doi: 10.21608/jabps.2020.21568.1065 https://www.researchgate.net/publication/340259234_Improving_Skin_Hardness_and_Thickness_using_a_combination_of_Omega-3_Fatty_Acid_and_Aloe_Vera_Oil_Pilot_study 
  69. Congress.gov. H.R. 2 – Agricultural Improvement Act of 2018. Retrieved from https://www.congress.gov/bill/115th-congress/house-bill/2/text
  70. Ibid.
  71. Ibid.
  72. Hudak, J. (2018, Dec. 14). The Farm Bill, hemp legalization and the status of CBD: An explainer. Retrieved from https://www.brookings.edu/blog/fixgov/2018/12/14/the-farm-bill-hemp-and-cbd-explainer/ 
  73. United States Drug Enforcement Administration. Drug Scheduling. Retrieved from https://www.dea.gov/drug-scheduling   
  74. U.S. Food and Drug Administration. (2020, Oct. 1). Op. cit. 
  75. Ibid.
  76. South Dakota Office of the Attorney General. (2019, March 25). Attorney General Ravnsborg Clarifies Questions Regarding Industrial Hemp and CBD (Cannabidiol) Oil. https://atg.sd.gov/OurOffice/Media/pressreleasesdetail.aspx?id=2167
  77. Washington State Department of Agriculture. Restrictions on the Use of Hemp CBD as a Food Ingredient. https://agr.wa.gov/departments/food-safety/food-safety/hemp-cbd-in-food
  78. ECHO. (2017, April 18). Op. cit. 
  79. Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Op. cit.
  80. Palmieri, B., Laurino, C., & Vadalà, M. (2019). Op. cit.
  81. Ibid.
  82. Scheau, C., Badarau, I. A., Mihai, L. G., Scheau, et. al. (2020). Op. cit.
  83. Ibid.
  84. National Eczema Association. Prescription Oral – Immunosuppresants. Op. cit.
  85. MedlinePlus. (2020, Aug. 31). Op. cit.
  86. Ibid.
  87. Medline Plus. (2016, Feb. 15). Op. cit.
  88. Mayo Clinic. (2020, June 12). Atopic dermatitis (eczema). Retrieved from https://www.mayoclinic.org/diseases-conditions/atopic-dermatitis-eczema/diagnosis-treatment/drc-20353279
  89. National Eczema Association. Prescription Injectables – Biologics. Retrieved from https://nationaleczema.org/eczema/treatment/dupixent/ 
  90. Hess, C., Krämer, M., & Madea, B. (2017). Topical application of THC containing products is not able to cause positive cannabinoid finding in blood or urine. Forensic science international, 272, 68–71. https://doi.org/10.1016/j.forsciint.2017.01.008
  91. Bayle, A. (2018, July 31). CBD Dosage – How much CBD should I take?. Hemppedia. Retrieved from https://hemppedia.org/cbd-dosage/ 
  92. New York State Governor. (2020, Oct. 28). Governor Cuomo Announces Proposed Regulations for Cannabinoid Hemp Products. https://www.governor.ny.gov/news/governor-cuomo-announces-proposed-regulations-cannabinoid-hemp-products
  93. Colorado Department of Public Health and Environment. Hemp in food. Retrieved from https://cdphe.colorado.gov/hemp-food
  94. Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Op. cit. 
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