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Best CBD Oil for Menopause

Managing menopausal symptoms can be challenging. If you want to try cannabidiol (CBD) products, here is some pertinent information to help you find the best CBD oil for menopause.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Sunsoil CBD Oil Drops, Chocolate Mint Flavor


3.6 out of 5
  1. Tastes great
  2. Uses hemp grown organically
  3. Laboratory tests done by a third party

Compare the best CBD Oil for Menopause in 2021

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Sunsoil CBD Oil Drops, Chocolate Mint Flavor
3.6 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

3.5 out of 5

5.0 out of 5

Best CBD Oil for Menopause

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Sunsoil CBD Oil Drops, Chocolate Mint Flavor
cbdc overall score
3.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.  Product selection is limited.
 The company tests its products thrice before making them available to the public.  The company uses lipid extraction methods.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Pros
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.
 The company tests its products thrice before making them available to the public.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Cons
 Product selection is limited.
 The company uses lipid extraction methods.
Overview

The flavor profile is refreshingly sweet, and it balances well with the higher CBD concentration. Promotes the absorption of CBD into your blood circulation.

How CBD Helps With Menopause

Cannabidiol (CBD) is an active element of cannabis. While CBD is a vital substance of medical marijuana, the compound is derived from hemp plants(1)

CBD is a plant-based cannabinoid (phytocannabinoid) with anti-inflammatory properties(2)

Menopause is linked with an abundance of additional changes, including inflammation(3). CBD’s antioxidative and anti-inflammatory properties(4) may help alleviate symptoms of menopause

CBD has structural similarities to tetrahydrocannabinol (THC), the primary psychotropic congener in the cannabis plant that produces a high. However, cannabidiol is non-psychoactive(5)

CBD works by interacting with the ECS or the endocannabinoid system. The ECS is present nearly in all parts of the body and functions by maintaining homeostasis(6)

Homeostasis is a process by which biological systems maintain stability while adapting to changing external environments(7)

This self-regulating system is achieved through a negative feedback loop that releases the endocannabinoids as they target the cannabinoid (CB) receptors(8)

Cannabinoid receptors CB1 and CB2 can be found on cells throughout the body(9).

 CB1 receptors play a significant role in motor regulation, memory processing, sleep, appetite, and pain sensation. Meanwhile, when activated, CB2 receptors stimulate a response that fights inflammation(10).  

The human body naturally produces endocannabinoids that interact with the CB receptors(11)

In case there is a shortage of endocannabinoids, phytocannabinoids may mimic their actions(12). Therefore, administering CBD and THC may help the endocannabinoid system retain its proper function(13)

However, it is difficult to measure how many CB receptors are stimulated and how much plant-based cannabinoids enter the bloodstream(14).  

Hence, significant studies must still be conducted to understand the impact of the interaction between CB receptors and cannabinoids

In addition, more research is also needed to verify CBD’s therapeutic effects and ability to help manage menopausal symptoms.    

Benefits of Using CBD for Menopause

Women experience physical and physiological changes as a result of hormonal alterations. 

Anxiety, mood swings, forgetfulness, stress, and sexual dysfunction are a few symptoms of menopause(15). Women also complain of sleep disturbances during menopause(16)

A study from the journal Neuropharmacology examined the effects of cannabidiol on sleep quality and the sleep cycle on animal models(17)

The study determined that CBD may block anxiety-induced rapid eye movement (REM) sleep alteration through its anxiolytic (anti-anxiety) effects(18)

Another research hypothesized that CBD may promote anti-anxiety effects in humans(19)

The results showed that cannabidiol’s anxiolytic effects are dose-dependent and may affect the function of brain structures associated with the control of anxiety-like states.

Aside from sleep disorders and anxiety, women undergoing menopause may also experience inflammation that may increase their health issues. 

For example, individuals going through menopause are at an increased risk of having Alzheimer’s disease. 

Research published in the Frontiers in Aging Neuroscience stated that estrogen is a potent anti-inflammatory agent(20)

Inflammation increases when estrogen levels decline, resulting in the possible onset and progression of Alzheimer’s disease (AD). 

Moreover, estrogen is deemed to protect the brain from cognitive decline. Thus, women going through menopause may experience changes in their cognition at this stage(21).

Due to cannabidiol’s antioxidative and anti-inflammatory properties, CBD may prevent inflammation usually accompanied by pain(22)

In addition, a 2019 study from the Journal of Pharmacopuncture implied that the CBD components of marijuana may help with Alzheimer’s disease(23)

Based on the research, CBD components may suppress the primary causal factors of AD. The researchers also suggested that using CBD with THC may be more beneficial than utilizing either compound alone(24)

Another study showed that women lose approximately 50% of their cancellous (trabecular) bone and 30% of their cortical bone during their lifetime. Moreover, about 40% of all postmenopausal women may also experience fractures(25)

Osteoporosis is one of the main public health problems in the U.S.A. It causes the bone to become weak and brittle(26)

The condition affects over 20 million people in the United States and leads to approximately 1.5 million fractures yearly. 

For midlife women, a risk factor for osteoporosis is menopause(27).

An animal study from the journal Cell Metabolism determined that cannabinoid receptor type one (CB1) may protect against age-related osteoporosis by regulating peak bone mass through a reaction to osteoclast activity(28)

Osteoclasts are cell types responsible for bone resorption in which the bones are absorbed and broken down by the body(29).     

All these studies may be promising and indicate CBD’s potential in managing menopausal symptoms. However, these studies are inconclusive. 

More research is required to determine cannabidiol’s therapeutic effect on menopause. 

How Long After Taking CBD Will It Start to Help With Menopause?

Inhaling cannabidiol using vape pens is the fastest way to benefit from the effects of CBD(30). However, vaping may cause damage to the lungs(31)

Meanwhile, a sublingual method of ingestion is the second quickest way to absorb CBD. Taking cannabidiol under the tongue ensures prompt delivery of the compound into your system(32)

You may also use a dropper for CBD oil or CBD tinctures to dispense the content straight into your mouth. Usually, CBD takes 15 to 30 minutes to take effect via this method(33)

On the other hand, topical CBD products may not take effect quickly since they are not absorbed only in targeted areas of the body. However, since information about cannabidiol’s long-term safety is limited, CBD topicals may be a safer choice(34)

After CBD Starts to Help, How Long Will It Last? 

Bioavailability refers to measuring the rate and fraction of a drug’s initial dose(35)

A systematic review published in Frontiers Pharmacology indicated that CBD’s bioavailability after smoking is 31%(36)

A half-life refers to the time it takes for a substance in your system to be reduced by 50%(37)

Results of a study showed that CBD’s half-life is between 1.4 and 10.9 hours after an oromucosal spray, two to five days after chronic oral administration, and 24 hours after intravenous medications(38).   

Risks and Side Effects of Using CBD for Menopause

The U.S. Food and Drug Administration (USFDA) does not regulate the production of CBD products. Before using CBD to manage menopause symptoms, you must first consult with a physician experienced in cannabis use. 

Although CBD is relatively safe(39), the non-psychoactive cannabinoid may still have a few side effects, including(40):

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue 

CBD Dosage for Menopause

There is no standard dose for menopause. However, most CBD brands may provide a recommended dosage for every product they have.

You may either start with a low dose or follow the recommended dosage by the CBD supplier and adjust it accordingly until you achieve your desired results. 

A review from Current Drug Safety suggested that humans can tolerate up to 1,500mg of CBD per day(41)

Still, it would help if you spoke with a physician before trying any CBD product to manage menopausal symptoms.  

CBD Usage Guide for Menopause

Menopausal women must choose high-quality CBD products if they want to maximize the benefits of CBD

However, with so many CBD brands in the market, you may have a hard time finding the best product for your needs. 

When choosing the best CBD oil for menopause, below are a few things you need to consider:

  1. Always check the ingredient list. You may opt for a full-spectrum CBD oil or CBD isolates. A CBD product is considered full-spectrum if all extracts of the cannabis plant, like terpenes and essential oils, are present. Full-spectrum CBD oil has a THC level of not more than 0.3%(42).Meanwhile, CBD isolates are a pure form of CBD(43).
  2. Support CBD brands that are transparent with their farming practices. A third-party laboratory must have tested all their products for consistency and potency. A certificate of analysis (CoA), which determines whether the product contains contaminants, is also necessary.
  3. There are many ways to administer CBD. You may try CBD edibles, topicals, or vapes.However, if you want to ingest CBD through vaping, make sure to do it with caution. Although vaping may provide immediate relief, this method of ingestion can trigger pulmonary illnesses(44).  It is always best to talk to a physician knowledgeable in cannabis product use before trying any CBD ingestion method to manage menopausal symptoms.   

Legality of CBD 

The U.S. Congress ratified the 2018 Farm Bill, legalizing the commercial use of industrial hemp and products obtained from the hemp plant(45)

About 36 states in the U.S. have legalized medical marijuana. Meanwhile, the remaining 14 states have passed laws allowing the use of CBD extracts, typically in oil form, with minimal or no THC content(46).

Product Frequently
Asked Questions

  • How can CBD help with menopause?

    Menopausal women may experience sleep disturbances and fluctuations in estrogen levels. CBD’s purported therapeutic effects on sleep and hormones(47) may help women trying high-quality CBD brands for wellness.

    Several studies have determined the various health benefits of cannabidiol in menopause symptoms. However, while results may be promising, they are inconclusive.   

  • What evidence of research exists to say that CBD helps with menopause?

    There is no direct evidence that demonstrates how CBD helps with menopause. However, several studies show how CBD may help with symptoms related to menopause.

    For instance, CBD’s antioxidative and anti-inflammatory properties may help prevent inflammation usually accompanied by pain(48).

  • Is there any evidence that CBD can make menopause worse?

    There is no direct link between cannabidiol and worsening symptoms of menopause. However, using CBD may induce side effects, such as irritability and drowsiness(49).

  • Will CBD interact with any current medications I may be taking for menopause?

    Based on a Journal of Clinical Medicine study, CBD may interact with other medications, including antipsychotics and antidepressants(50).

  • Are there other treatments I should consider alongside CBD to help with menopause?

    Physicians can prescribe hormone replacement therapy or the use of medical treatments to replace progesterone and estrogen in the body during menopause(51)

    However, ensure to speak with your healthcare provider before using cannabidiol along with other treatments to avoid possible side effects.

  • Can I fail a drug test if I use CBD for menopause?

    Based on clinical trials, the oral administration of CBD does not result in detectable THC blood concentrations(52). Using CBD for menopause may not result in a positive drug test.

  • What is the CBD dosage for menopause?

    CBD as medication has not been approved by the U.S. Food and Drug Administration (FDA). There are no official dosage guidelines for CBD. 

    The general rule is to go slow and start low. For menopause, you may begin with a low CBD concentration and potency and gradually increase the dose until you get the desired effects.

  • What are the common menopausal symptoms?

    Menopause is an aspect of a woman’s life that marks the end of her menstrual cycle.  In the months leading up to perimenopause (around menopause), you may experience these symptoms(53):

    • Hot flashes (sudden rise of body temperature
    • Vaginal dryness
    • Night sweats
    • Sleep problems 
    • Weight gain
  • What are the causes of menopause?

    Menopause can result from hormonal changes. When you reach your late 30s, your ovaries start making less progesterone and estrogen, the hormones that regulate menstruation(54)

    After menopause, your risk of various health conditions may increase, such as high blood pressure, bone loss or loss of bone density, and joint pain(55)

    However, there is no direct evidence linking CBD’s benefits in menopause. You should consult with your physician before using CBD oil products in managing menopausal symptoms.


  1. Cannabidiol (CBD)-what we know and what we don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  2. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  3. Menopause, obesity and inflammation: interactive risk factors for Alzheimer’s disease
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493396/
  4. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  5. Immune Responses Regulated by Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/
  6. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  7. Homeostasis: The Underappreciated and Far Too Often Ignored Central Organizing Principle of Physiology
    https://www.frontiersin.org/articles/10.3389/fphys.2020.00200/full
  8. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  9. A Look at the Endocannabinoid System’s CB1 and CB2 Receptors
    https://echoconnection.org/look-endocannabinoid-systems-cb1-cb2-receptors/
  10. Ibid.
  11. Ibid.
  12. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  13. A Look at the Endocannabinoid System’s CB1 and CB2 Receptors
    https://echoconnection.org/look-endocannabinoid-systems-cb1-cb2-receptors/
  14. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  15. Mood, depression, and reproductive hormones in the menopausal transition
    https://pubmed.ncbi.nlm.nih.gov/16414327/
  16. Sleep Disorders and Menopause
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718648/
  17. Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats
    https://pubmed.ncbi.nlm.nih.gov/21867717/
  18. Ibid.
  19. The Anxiolytic Effects of Cannabidiol (CBD)
    https://www.elsevier.com/__data/assets/pdf_file/0003/259068/CHe13.pdf
  20. Menopause, obesity, and inflammation: interactive risk factors for Alzheimer’s disease
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493396/
  21. Ibid.
  22. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  23. A Review on Studies of Marijuana for Alzheimer’s Disease – Focusing on CBD, THC
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970569/
  24. Ibid.
  25. Bone Mineral Density Changes During the Menopause Transition in a Multiethnic Cohort of Women
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266953/
  26. Ibid.
  27. Ibid.
  28. Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells
    https://pubmed.ncbi.nlm.nih.gov/19656492/
  29. Regulation of osteoclast activity
    https://pubmed.ncbi.nlm.nih.gov/10503925/
  30. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  31. Is It Safe to Vape CBD?
    https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/
  32. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  33. Ibid.
  34. Ibid.
  35. Drug Bioavailability
    https://www.ncbi.nlm.nih.gov/books/NBK557852/
  36. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  37. Half-Life
    https://www.ncbi.nlm.nih.gov/books/NBK554498/
  38. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  39. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  40. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700#
  41. Safety and side effects of cannabidiol, a Cannabis sativa constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  42. Cannabidiol primer for healthcare professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  43. Ibid.
  44. Vaping: An Emerging Health Hazard
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186084/
  45. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  46. States with Legal Cannabidiol (CBD)
    https://medicalmarijuana.procon.org/states-with-legal-cannabidiol-cbd/
  47. Why are women using CBD products — and do they work?
    https://www.health.harvard.edu/blog/why-are-women-using-cbd-products-and-do-they-work-2019111818317
  48. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  49. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
    https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
  50. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  51. Hormone therapy: Is it right for you?
    https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372
  52. FAQs About Cannabidiol (CBD)
    https://norml.org/marijuana/fact-sheets/faqs-about-cannabidiol-cbd/
  53. Menopause
    https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397
  54. Ibid.
  55. Ibid.
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