Best CBD Oil for Hashimoto’s Disease

Are you looking for natural alternatives to help with symptoms of Hashimoto’s disease? Read about how cannabidiol or CBD may help with symptoms of thyroid problems like Hashimoto’s disease.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil

4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil

5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg

4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg

4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures

4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil

3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Compare the Best CBD Oil for Hashimoto’s Disease in 2022

ProductPotencyPurityCustomer ServiceTypeExtractionTransparencyAbsorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5
5.0 out of 5
3.5 out of 5
3.0 out of 5
5.0 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5
5.0 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5
4.5 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5
2.5 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5
4.5 out of 5
3.5 out of 5
2.5 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5

Best CBD Oil for Hashimoto’s Disease

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score

4.8

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Mid-strength

No other flavors

Natural peppermint flavor

Made from 100% organic and natural ingredients

Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Pure CBD hemp

No other flavors

All natural

Approximately 300 drops total

Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Extra Strength

Tastes bitter

No artificial flavoring or colors

No THC-free option

Made from 100% organic and natural ingredients

Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score

4.6

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Light Spearmint flavor

No other flavor

Non-THC, Non-detected in drug test

Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score

4.7

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Various delicious flavors to choose from

cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options

Has vegan, organic, and gluten-free ingredients

Free shipping for this particular product within USA

World-class customer service team

Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score

4.4

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

60-Day Satisfaction Guarantee

Dropper is a bit shaky

Various strengths

Oil extracted from aerial plant parts of US grown industrial hemp

Sourced from non-GMO industrial hemp grown in the USA through natural farming practices

Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score

4.6

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Pure CBD hemp

No other flavors

All natural

A bit pricey compared to competitors

Approximately 100 drops total

Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score

4.4

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Vegan and Gluten free

Does not ship internationally

Has a third-party lab test

Wide variety of CBD strengths and sizes

Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score

3.9

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

ProsCons

Wide variety of flavors

Incomplete information about the product

Lab test results are complete

Does not ship to all international countries

30-day money-back guarantee

Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How CBD May Help With Hashimoto’s Disease

CBD is a nonintoxicating cannabis plant compound that may provide anti-inflammatory benefits(1).

The phytocannabinoid (plant-based cannabinoid) may help manage certain medical conditions(2). It works by engaging the body’s ECS or endocannabinoid system(3).

The ECS comprises several essential components, like the CB1 and CB2 cannabinoid receptors. These receptors help regulate many bodily functions like sleep, learning, eating, pain control, and immune and inflammatory responses(4).

Cannabinoids are chemical substances that may help suppress inflammatory cytokine production and immune activation(5).

Cytokines are proteins that help control the activity and growth of immune system cells, regulating the body’s inflammatory and immune responses(6).

One study mentioned that cytokines may help induce tolerance against autoimmune thyroid diseases, including Graves disease and Hashimoto’s thyroiditis(7).

Graves disease is an autoimmunity disorder caused by excessive thyroid production leading to hyperthyroidism(8)

Symptoms of hyperthyroidism include rapid heartbeat, weight loss, muscle weakness, and frequent bowel movements(9).

Benefits and Uses of CBD for Hashimoto’s Disease

There has been no conclusive clinical evidence indicating CBD directly helps with Hashimoto’s disease. Additional research is required to determine CBD’s potential in managing this autoimmune condition and other thyroid disorders.

Hashimoto’s thyroiditis causes the thyroid to become inflamed or enlarged(10). One primary benefit of CBD is as an anti-inflammatory agent(11). This may be one area of interest for research on the role of CBD in addressing Hashimoto’s disease.

Another symptom of Hashimoto’s disease is joint pain(12). Animal studies suggest CBD may have pain-relieving properties(13)

However, the results of animal studies still need to be validated in human studies.

CBD Dosage for Hashimoto’s Disease

There are currently no standard CBD dosage guides specific to Hashimoto’s disease. However, the general recommendation is to start with a lower dose when taking CBD(14).

Factors that may affect CBD dosage include diet, exercise, genetics, stress levels, and existing health conditions(15).

If you have symptoms of Hashimoto’s disease or other medical conditions, consult your doctor for proper diagnosis and treatment before taking CBD or deciding on a specific CBD dosage.

How to Take CBD Oil for Hashimoto’s Disease

There are various delivery methods to take CBD oil to help manage the symptoms of Hashimoto’s disease and other thyroid conditions. These methods are the following:

  • Sublingual administration: CBD oil is delivered sublingually or under the tongue, allowing CBD to bypass the digestive tract and enter the bloodstream directly.

Sublingual methods include CBD oil tinctures using droppers or oromucosal sprays.

  • Oral administration: CBD oil passes through the digestive tract before entering the bloodstream.

Some oral CBD products include capsules and edibles, such as CBD gummies and chews.

  • Topical application: CBD oil is applied directly to the skin. Topical products include creams, lotions, balms, and ointments.
  • Vaping: CBD is delivered into the body through inhalation. Vaping is considered one of the fastest ways to administer CBD into the body(16).

However, vaping can cause potential health risks related to lung disease(17). Consult your doctor before using vape products if you have existing health conditions.

How Long Does CBD Take to Help With Hashimoto’s Disease?

There are no specific studies to date that focus on onset times of CBD for Hashimoto’s disease.

Generally, the onset time for CBD oral ingestion is around 30 to 90 minutes. Meanwhile, CBD may take effect 15 to 30 minutes after application using sublingual and topical methods. For CBD inhalation, the onset time is about 2 to 15 minutes(18).

How Long Will CBD Help With Hashimoto’s Disease?

To date, conclusive scientific data is insufficient to determine the duration of CBD’s effects on Hashimoto’s disease.

A 2018 review stated that CBD administered at 5 milligrams (mg) and 20mg doses using oromucosal sprays has a half-life of 1.4 and 10.9 hours(19).

Half-life is the period a drug takes to decrease its concentration or quantity within the body by 50%.

Side Effects and Risks of Using CBD for Hashimoto’s Disease

At present, no specific studies determining CBD’s side effects on individuals with Hashimoto’s disease have been conducted.

In general, CBD’s side effects include diarrhea, fatigue, appetite loss, drowsiness, and dry mouth(20).

Choosing the Right CBD for Hashimoto’s Disease

To choose the right CBD product to help manage the symptoms of Hashimoto’s disease and maintain thyroid function, you must consider various factors, such as extraction methods or types of CBD products.

Manufacturers extract CBD from the cannabis plant using extraction methods such as carbon dioxide (CO2), hydrocarbon, or ethanol. Afterward, CBD is categorized as full-spectrum, broad-spectrum, or isolate.

Full-spectrum CBD oil contains all the cannabis plant compounds and cannabinoids, such as tetrahydrocannabinol (THC), flavonoids, and terpenes.

Flavonoids give plants their distinct colors, while terpenes produce an aromatic effect in plants(21).

Broad-spectrum CBD oil also contains most compounds in full-spectrum CBD oil. However, broad-spectrum CBD products do not contain THC.

Meanwhile, isolates contain pure CBD only. No other cannabinoids or compounds are included.

You may consider isolates or broad-spectrum products if you prefer to take CBD oil without THC’s psychoactive effects.

Legality of CBD

The 2018 Farm Bill removed hemp-based CBD products with less than 0.3% THC from the list of controlled substances.

Still, CBD products with more than 0.3% THC are illegal under federal law(22).

Check your state’s laws and review your CBD product’s THC content to determine whether CBD is legal in your area.

What Is Hashimoto’s Disease?

Hashimoto’s disease, sometimes called chronic lymphocytic thyroiditis, is an autoimmune disease that affects the thyroid gland. The thyroid gland produces thyroid hormones needed for metabolism.

The disease causes immune cells to attack thyroid hormone-producing cells, resulting in hypothyroidism or thyroid hormone production decline.

The progression of Hashimoto’s disease may lead to goiter or thyroid gland enlargement.

Symptoms of Hashimoto’s disease include(23):

  • Fatigue
  • Depression
  • Weight gain
  • Muscle pain
  • Hair loss
  • Dry skin
  • Constipation
  • Slow heart rate

Other signs of Hashimoto’s disease are muscle weakness, joint pain, increased sleepiness, and irregular menstrual bleeding(24).

Doctors diagnose Hashimoto’s disease using blood tests, thyroid-stimulating hormone (TSH) tests, or thyroid antibody tests.

If Hashimoto’s disease progresses to hypothyroidism, doctors may prescribe thyroid medications like levothyroxine (Synthroid, Levoxyl, Levothroid)(25).

Your doctor may recommend radioactive iodine in the case of hyperthyroidism.

Product Frequently
Asked Questions

  • How can CBD help with Hashimoto’s disease?

    CBD is a cannabinoid known to provide anti-inflammatory benefits(26). Cannabinoids may help suppress immune activation and inflammatory cytokine production(27).

    Cytokines play a role in managing autoimmune thyroid diseases, including Hashimoto’s thyroiditis(28).

  • What evidence or research exists to say that CBD oil helps with Hashimoto’s disease?

    Joint pain is one symptom of Hashimoto’s disease(29). Animal studies show CBD may help reduce pain(30). However, more studies are needed to validate the pain-relieving benefits on humans.

  • Is there any evidence that CBD can make Hashimoto’s disease worse?

    There is presently no direct evidence suggesting CBD worsens Hashimoto’s disease.

  • Will CBD interact with any current medication I may be taking for Hashimoto’s disease?

    CBD may prevent the activity of cytochrome P450 enzymes that metabolize various pharmaceutical drugs. Inhibiting these enzymes may cause the drugs to take longer to take effect(31).

  • Are there other treatments I should consider alongside CBD to help with Hashimoto’s disease?

    Exercising, eating a balanced diet, and sleeping well can help manage the symptoms of Hashimoto’s disease and maintain thyroid health.

    Ask your doctor for more information about other remedies, nutrients, supplements, or alternative meds you may take with CBD.

  • Can I fail a drug test if I use CBD for Hashimoto’s disease?

    CBD products with less than 0.3% THC do not cause a drug test failure. However, frequent and prolonged CBD oil use may cause THC levels in your body to increase(32), increasing the probability of a positive result.

  • What is the dosage for Hashimoto’s disease?

    To date, there are no standard CBD dosage guides for Hashimoto’s disease. In general, users may start taking CBD at a lower dose(33).

  • What are the possible side effects of CBD for Hashimoto’s disease?

    CBD’s known side effects include drowsiness, appetite loss, dry mouth, fatigue, and diarrhea(34).


  1. Page 102-103 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  2. Acute inflammation and pathogenesis of SARS-CoV-2 infection: Cannabidiol as a potential anti-inflammatory treatment?
    https://doi.org/10.1016/j.cytogfr.2020.05.008
  3. Page 103 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  4. The endocannabinoid system: Essential and mysterious
    https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
  5. Acute inflammation and pathogenesis of SARS-CoV-2 infection: Cannabidiol as a potential anti-inflammatory treatment?
    https://doi.org/10.1016/j.cytogfr.2020.05.008
  6. Cytokines and Their Side Effects
    https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/immunotherapy/cytokines.html
  7. Role of Cytokines in the Pathogenesis and Suppression of Thyroid Autoimmunity
    https://doi.org/10.1089/jir.2011.0049
  8. Ibid.
  9. Hyperthyroidism (Overactive Thyroid)
    https://www.niddk.nih.gov/health-information/endocrine-diseases/hyperthyroidism
  10. Hashimoto’s disease
    https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease
  11. Page 103 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  12. Hashimoto’s disease: Symptoms & causes
    https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855
  13. CBD for Arthritis Pain: What You Should Know
    https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain
  14. CBD dosing
    https://www.projectcbd.org/guidance/cbd-dosing
  15. Ibid.
  16. Best way to take CBD
    https://www.projectcbd.org/guidance/best-way-take-cbd
  17. Can vaping damage your lungs? What we do (and don’t) know
    https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  18. Page 190-193 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  19. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://doi.org/10.3389/fphar.2018.01365
  20. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  21. Page 121 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  22. CBD & THC: Myths and misconceptions
    https://www.projectcbd.org/cbd-101/cbd-misconceptions
  23. Hashimoto’s Disease
    https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease
  24. Hashimoto’s disease: Symptoms & causes
    https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855
  25. Hashimoto’s Disease
    https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease
  26. Page 102-103 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  27. Acute inflammation and pathogenesis of SARS-CoV-2 infection: Cannabidiol as a potential anti-inflammatory treatment?
    https://doi.org/10.1016/j.cytogfr.2020.05.008
  28. Role of Cytokines in the Pathogenesis and Suppression of Thyroid Autoimmunity
    https://doi.org/10.1089/jir.2011.0049
  29. Hashimoto’s disease: Symptoms & causes
    https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855
  30. CBD for Arthritis Pain: What You Should Know
    https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain
  31. Page 114-115 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  32. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  33. CBD dosing
    https://www.projectcbd.org/guidance/cbd-dosing
  34. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700

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