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Best CBD Oil for Colds

The common cold has no cure, so your best option is to improve your immune response against cold symptoms. At CBD Clinicals, we gather the best CBD oils for colds to help you make informed purchase decisions.

Editor's Pick

Spruce 750mg Lab Grade CBD Oil

Best Organic

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

Editor's Pick

Spruce 2400mg Lab Grade CBD Oil

Best Seller

Avida Full Spectrum CBD Oil Tincture 500mg

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg

Best THC-Free

CBDistillery THC Free CBD Oil Tinctures

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

Best Starter

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

Hemp Bombs 750mg CBD Oil

Best Allergy Friendly

Sunsoil CBD Oil Drops, Chocolate Mint Flavor

Rating
4.8 out of 5

5.0 out of 5

5.0 out of 5

4.6 out of 5

4.7 out of 5

4.4 out of 5

4.4 out of 5

4.6 out of 5

3.9 out of 5

3.6 out of 5
Highlights
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)
  1. made using only CBD sourced from medical hemp
  2. available in many flavours
  3. safe for daily use
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription
  1. Tastes great
  2. Uses hemp grown organically
  3. Laboratory tests done by a third party

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Compare the Best CBD Oil for Colds in 2021

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Sunsoil CBD Oil Drops, Chocolate Mint Flavor
3.6 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

3.5 out of 5

5.0 out of 5

Best CBD Oil for Colds

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pro's
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Con's
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pro's
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Con's
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pro's
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Con's
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pro's
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Con's
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pro's
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Con's
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pro's
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Con's
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pro's
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Con's
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pro's
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Con's
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pro's
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Con's
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Sunsoil CBD Oil Drops, Chocolate Mint Flavor
cbdc overall score
3.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pro's Con's
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.  Product selection is limited.
 The company tests its products thrice before making them available to the public.  The company uses lipid extraction methods.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Pro's
 Sunsoil CBD is committed to providing high-quality products at an affordable cost.
 The company tests its products thrice before making them available to the public.
 From cultivation to packaging, everything is done in Sunsoil CBD grounds.
 Organic and sustainable farming is at the company’s core.
Con's
 Product selection is limited.
 The company uses lipid extraction methods.
Overview

The flavor profile is refreshingly sweet, and it balances well with the higher CBD concentration. Promotes the absorption of CBD into your blood circulation.

How CBD Helps With Colds

Cannabidiol (CBD) is a natural remedy that purportedly has therapeutic and antiviral properties that may alleviate common cold symptoms, including sneezing, sore throat, and stuffy nose.

The common cold occurs when inflammation affects your sinuses and upper respiratory tract. Rhinoviruses are common viral causes of colds(1).

Researchers observed CBD’s anti-inflammatory and analgesic effects, from which cold patients may benefit. Sativex, a mouth spray meant for pain relief, combines CBD with tetrahydrocannabinol (THC)(2).

People can become vulnerable to the common cold due to poor sleep habits. A study noted that people with low-quality sleep are more susceptible to illnesses when exposed to a rhinovirus(3).

CBD potentially improves sleep quality among anxiety patients with sleep problems(4).

Our bodies feel CBD’s supposed effects when the compound interacts with the cannabinoid receptors of the endocannabinoid system (ECS).

The ECS is a unique system that modulates our body’s biological balance in response to environmental changes(5).

Experts believe that the ECS regulates mood, cognition, and chronic pain perception through its cannabinoid receptors(6).

CBD’s capability to bind with CB1 and CB2 cannabinoid receptors contributes to its ability to suppress inflammatory responses(7).

Researchers of a 2008 study believe that the ECS helps with sleep modulation by inducing sleep through CB1 receptor activation(8).

Meanwhile, a study on respiratory viral infections stated that activating CB2 receptors leads to anti-inflammatory effects in the body(9).

Although the existing studies are promising, there is no direct scientific evidence supporting CBD’s ability to alleviate colds symptoms.

How to Take CBD Oil for Colds

You may take CBD for colds in consumable forms, such as CBD gummies, CBD brownies, and CBD tablets. This method of consuming CBD is more straightforward than other methods.

Sublingual administration is another method, suitable for a more controlled CBD intake. This option involves taking a calibrated dropper included in CBD tincture products and applying a few drops of CBD oil under your tongue.

When you leave the oil under your tongue for about 90 seconds before swallowing, you allow your mucous membranes to absorb the tincture.

Some CBD companies sell CBD topical products, such as lotions, balms, creams, and salves. You may rub such products on your chest to help relieve congestion from colds.

You may prefer to inhale CBD through flavored or unflavored vape juices. Consider this method when you opt for peppermint or fruity flavors over the natural, earthy flavor of pure CBD oil.

Vaping CBD allows the compound to enter your system quickly through your lungs. However, note that CBD vapes may worsen lung disorders(10).

Thus, when using CBD for colds for the first time, be sure to seek medical advice from a licensed physician. It is essential to get advice from a doctor with significant experience in CBD and medical marijuana usage.

How Soon Does It Take to Feel CBD’s Effects for Colds?

How soon you will feel CBD’s purported therapeutic effects for colds may depend on how you administer CBD.

You may find CBD oil’s natural flavor unpleasant through sublingual administration. However, this method allows for the effects of CBD to be felt within 15 to 45 minutes(11).

CBD topicals, such as CBD creams and CBD transdermal patches, work instantly after rubbing the product onto your skin.

You can also apply topical CBD oil alone or combine the product with cream or lotion(12). If you combine CBD topicals with massage therapy, you may feel relief in about 15 minutes(13).

When using a vape pen to inhale CBD vape juices, you will feel its anti-anxiety effects within minutes, which will keep you steady between three to five hours after inhalation(14).

How to Choose the Best CBD for Colds

There has been no approved CBD treatment for colds. Meanwhile, the United States Food and Drug Administration (FDA) continues to support scientifically-based research into the medicinal uses of products containing cannabis or cannabis-derived compounds like CBD(15).

You may still choose among the three CBD forms currently available on the market: full-spectrum CBD, broad-spectrum CBD, and CBD isolates.

Full-spectrum CBD oil contains all of Cannabis sativa plants’ naturally occurring compounds, including terpenes, fatty acids, flavonoids, and cannabinoids.

A high-quality full-spectrum hemp extract has higher cannabidiol levels than the other compounds.

CBD oil that contains all of cannabis’ naturally occurring chemical compounds produce the “entourage effect.” This process involves combining all cannabis plant compounds to have synergistic effects that may benefit common cold patients(16).

To obtain full-spectrum CBD, industrial hemp plants undergo extraction methods, such as CO2 extraction, alcohol extraction, or steam distillation.

Researchers of a 2018 study stated that the FDA recognizes the supercritical CO2 extraction process as safe in pharmaceutical manufacturing(17)

Manufacturers then mix the pure hemp oil with a carrier oil, such as MCT oil or hempseed oil.

While the broad-spectrum CBD variant is THC-free, it still contains almost the same phytocannabinoids as full-spectrum products. Some people prefer this option for its lack of psychoactive THC compounds.

Finally, CBD isolate is the purest type of CBD on the market, which brands typically sell in crystalline or powdered form.

Manufacturers obtain CBD isolate products by removing all other hemp plants’ compounds during the extraction process, leaving only pure CBD.

Despite the different CBD types, consumers must only purchase the best quality products available to maximize the purported health benefits of CBD. Consider our tips when choosing the best CBD oil for colds.

  • Look for the CBD product’s third-party lab results or certificate of analysis (COA). This document indicates that an item has undergone thorough lab testing.

CBD products of the highest quality have the exact specifications listed on the product label.

  • Ensure that the CBD product you intend to purchase is derived from organic hemp. High-quality CBD products from organic hemp have THC less than 0.3%, which is the federally legal limit.
  • Consult your family health care practitioner before using CBD for cold symptoms. We recommend consulting a doctor with significant experience in medical marijuana and CBD usage.
  • Choose CBD shops or dispensaries that offer a money-back guarantee for their products to ensure customer satisfaction. Reliable brands also include disclaimers that CBD is not meant to cure any medical conditions.

CBD Dosage for Colds

The FDA has no approved dosing guide for CBD for colds. However, human clinical trials on cannabidiol may provide insight into safe and reliable CBD dosages.

In one study focusing on CBD for anxiety, a daily dose of 25 mg to 175 mg CBD elicited sufficient clinical response(18). The researchers also noted that patients tolerated CBD generally well, with only some reported side effects.

In another study, results showed that human subjects could tolerate high CBD doses reaching up to 1,500mg per day(19).

Benefits of Using CBD for Colds

CBD’s purported therapeutic effects may protect you from the causes of common colds, including inflammation and poor sleep habits.

Researchers observed CBD’s anti-inflammatory and analgesic effects, which cold patients may benefit from(20).

Common colds occur when your nose and upper respiratory tracts experience inflammation, particularly from rhinoviruses(21).

CBD may also improve sleep quality among anxiety patients with sleep problems(22).

A study noted that people might become vulnerable to the common cold due to poor sleep habits(23).

Risks of Using CBD for Colds

Despite the promising results from existing studies, there is no direct clinical evidence proving that CBD can effectively treat cold symptoms.

CBD is “generally well tolerated with a good safety profile,” according to The World Health Organization (WHO)(24). Still, the FDA does not approve CBD oil products’ marketing as dietary supplements or medicine for any medical condition(25).

The FDA has only approved Epidiolex as a CBD treatment for rare forms of epilepsy(26).

Using CBD for colds may induce side effects, including appetite changes, fatigue, diarrhea, nausea, and drowsiness(27).

CBD also has the risk of interacting with certain supplements or medications that you may already be taking(28).

Legality of CBD

Each state in the USA has varying degrees of regulation for using CBD. There are currently only 47 out of the 50 states where you can use CBD legally on a federal level(29).

You may only travel between states that share similar CBD restrictions if you plan to carry CBD for your colds when traveling.

Usually, you would associate CBD’s legality in the US with the 2018 Farm Bill(30). This law differentiated hemp plants from marijuana plants by redefining hemp as cannabis containing under 0.3% THC on a dry weight basis.

Marijuana plants are cannabis plants with more than the established limit. Cannabis sativa plants may come in hemp and marijuana varieties.

With hemp plants’ declassification as marijuana plants, the 1970 Federal Controlled Substances Act no longer covers them in its Schedule I category(31)

Schedule I drugs consist of potentially abusive or addictive substances without any officially recognized health benefits.

The 2018 Farm Bill also gave the FDA the authority to moderate CBD’s circulation on the market(32). The agency penalizes CBD companies that use CBD’s unproven health benefits to sell CBD products.

The 2018 Farm Bill relaxed the legal restrictions on the production, manufacture, and ownership of hemp-derived CBD products. Local laws may still supersede federal law since state laws are the primary authority in drug-related offenses(33).

Product Frequently
Asked Questions

  • How can CBD help with colds?

    CBD’s supposed anti-inflammatory properties may help relieve you of common cold symptoms(34). The common cold occurs when inflammation affects your nose and upper respiratory tract(35).

  • What evidence or research exists to say that CBD helps with colds?

    While there is no clinical evidence that can prove CBD’s effectiveness in fighting cold symptoms, CBD can improve your sleeping habits for a better immune system(36). Low-quality sleep can make you susceptible to illnesses, including the common cold(37).

  • Is there any evidence that CBD worsens colds?

    There is no direct evidence linking CBD to worsening cold symptoms. Still, using CBD for colds may induce side effects, including appetite changes, fatigue, diarrhea, nausea, and drowsiness(38).

  • Will CBD interact with any cold medication?

    Although there is no evidence of CBD interacting with specific cold medication, the risk of CBD interacting with existing drugs remains(39).

  • Are there other treatments I should consider alongside CBD to help with colds?

    Since the common cold has no cure, there are limited options for treatments to consider alongside CBD for colds. 

    You may still combine CBD topicals with massage therapy to help body aches caused by the common cold(40). Some CBD products also include zinc, probiotics, and vitamin C for overall wellness.

  • Can I fail a drug test if I use CBD for colds?

    Unlike THC, cannabidiol does not show up on a drug test. However, high-quality CBD products may contain trace amounts of THC, which may accumulate with frequent use.

    Accumulated amounts may be detected on a drug test(41). It would help if you remain cautious when taking CBD products with THC, especially with a scheduled drug test.

  • What is the CBD dosage for colds?

    The FDA has no approved dosing guide for CBD for colds. However, a study noted that humans could tolerate up to 1,500mg CBD per day(42).


  1. John Hopkins Medicine. Common Cold. Retrieved from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/common-cold
  2. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. doi:10.2147/tcrm.s1928
  3. Cohen S, Doyle WJ, Alper CM, Janicki-Deverts D, Turner RB. Sleep habits and susceptibility to the common cold. Arch Intern Med. 2009;169(1):62-67. doi:10.1001/archinternmed.2008.505
  4. Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi:10.7812/TPP/18-041
  5. UCLA Health. Human Endocannabinoid System. Retrieved from: https://www.uclahealth.org/cannabis/human-endocannabinoid-system.
  6. Stampanoni Bassi M, Gilio L, Maffei P, et al. Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression. Front Mol Neurosci. 2018;11:424. Published 2018 Nov 20. doi:10.3389/fnmol.2018.00424
  7. Nichols JM, Kaplan BLF. Immune Responses Regulated by Cannabidiol. Cannabis Cannabinoid Res. 2020;5(1):12-31. Published 2020 Feb 27. doi:10.1089/can.2018.0073
  8. Murillo-Rodríguez E. The role of the CB1 receptor in the regulation of sleep. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32(6):1420-1427. doi:10.1016/j.pnpbp.2008.04.008
  9. Tahamtan A, Samieipoor Y, Nayeri FS, et al. Effects of cannabinoid receptor type 2 in respiratory syncytial virus infection in human subjects and mice. Virulence. 2018;9(1):217-230. doi:10.1080/21505594.2017.1389369
  10. Chand HS, Muthumalage T, Maziak W, Rahman I. Pulmonary Toxicity and the Pathophysiology of Electronic Cigarette, or Vaping Product, Use Associated Lung Injury. Front Pharmacol. 2020;10:1619. Published 2020 Jan 14. doi:10.3389/fphar.2019.01619
  11. Arthritis Foundation. CBD for Arthritis Pain: What You Should Know. Retrieved from https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain.
  12. Freeman, J. (2019, Oct 4). Does CBD Oil Really Help Treat Arthritis Pain? Retrieved from https://www.rheumatoidarthritis.org/cbd-oil/.
  13. Taskar, P., Adelli, G., Patil, A., Lakhani, P., Ashour, E., Gul, W., ElSohly, M., & Majumdar, S. (2019). Analog Derivatization of Cannabidiol for Improved Ocular Permeation. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 35(5), 301–310. https://doi.org/10.1089/jop.2018.0141
  14. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478. https://doi.org/10.3390/molecules23102478
  15. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). U.S. Food & Drug Association. 2020 Oct 1. Retrieved from https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  16. Ferber, S.G., Namdar, D., Hen-Shoval, D., Eger, G., Koltai, H., Shoval, G., Shbiro, L., Weller, A. (2020). The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324885/
  17. Kankala RK, Chen BQ, Liu CG, Tang HX, Wang SB, Chen AZ. Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds. Int J Nanomedicine. 2018;13:4227–4245. Published 2018 Jul 23. doi:10.2147/IJN.S166124; Djerafi R, Masmoudi Y, Crampon C, Meniai A, Badens E. Supercritical anti-solvent precipitation of ethyl cellulose. J Supercrit Fluids. 2015;105:92–98.
  18. Shannon S, Lewis N, Lee H, Hughes S. op. cit.
  19. Bergamaschi MM, Queiroz RH, Zuardi AW, Crippa JA. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 2011;6(4):237-249. doi:10.2174/157488611798280924
  20. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. doi:10.2147/tcrm.s1928
  21. John Hopkins Medicine. Common Cold. Retrieved from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/common-cold
  22. Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi:10.7812/TPP/18-041
  23. Cohen S, Doyle WJ, Alper CM, Janicki-Deverts D, Turner RB. Sleep habits and susceptibility to the common cold. Arch Intern Med. 2009;169(1):62-67. doi:10.1001/archinternmed.2008.505
  24. WHO. Expert Committee on Drug Dependence. (2017, Nov 6-10). Cannabidiol (CBD). Retrieved from https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf
  25. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). U.S. Food & Drug Administration. 2020 October 1. Retrieved from https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  26. FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy. U.S. Food & Drug Administration. 2020 March 27. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms
  27. Machado Bergamaschi, M., Helena Costa Queiroz, R., Waldo Zuardi, A., & Crippa, A. S. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current drug safety, 6(4), 237-249.
  28. Schmerling, R. (2020). Does CBD help with arthritis pain? Harvard Health Publishing. https://www.health.harvard.edu/blog/does-cbd-help-with-arthritis-pain-2020041019418
  29. Hemppedia (2019, May 31). Is CBD legal in all 50 states? – The complete 2020 Guide Retrieved from https://hemppedia.org/cbd-oil-legal-us/
  30. Farm Bill. U.S. Department of Agriculture. Retrieved from https://www.usda.gov/farmbill
  31. Comprehensive Drug Abuse Prevention and Control Act of 1970. FindLaw. 2019 February 4. Retrieved from https://criminal.findlaw.com/criminal-charges/comprehensive-drug-abuse-prevention-and-control-act-of-1970.htm
  32. Hudak, John. The Farm Bill, hemp legalization and the status of CBD: An explainer. The Brookings Institution. 2018 December 14. Retrieved from https://www.brookings.edu/blog/fixgov/2018/12/14/the-farm-bill-hemp-and-cbd-explainer/
  33. Mead A. (2019). Legal and Regulatory Issues Governing Cannabis and Cannabis-Derived Products in the United States. Frontiers in plant science, 10, 697. https://doi.org/10.3389/fpls.2019.00697
  34. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. doi:10.2147/tcrm.s1928
  35. John Hopkins Medicine. Common Cold. Retrieved from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/common-cold
  36. Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi:10.7812/TPP/18-041
  37. Cohen S, Doyle WJ, Alper CM, Janicki-Deverts D, Turner RB. Sleep habits and susceptibility to the common cold. Arch Intern Med. 2009;169(1):62-67. doi:10.1001/archinternmed.2008.505
  38. Machado Bergamaschi, M., Helena Costa Queiroz, R., Waldo Zuardi, A., & Crippa, A. S. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current drug safety, 6(4), 237-249.
  39. Schmerling, R. (2020). Does CBD help with arthritis pain? Harvard Health Publishing. https://www.health.harvard.edu/blog/does-cbd-help-with-arthritis-pain-2020041019418
  40. Loo M. (2009). Upper Respiratory Tract Infection. Integrative Medicine for Children, 450–455. https://doi.org/10.1016/B978-141602299-2.10060-X
  41. U.S. Food and Drug Administration. (2020, Oct. 1). FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). Retrieved from https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  42. Bergamaschi MM, Queiroz RH, Zuardi AW, Crippa JA. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 2011;6(4):237-249. doi:10.2174/157488611798280924
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