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Best CBD Oil for Carpal Tunnel Syndrome

Does your hand feel numb and weak because of carpal tunnel syndrome? CBD Clinicals has all the pertinent information about carpal tunnel syndrome and the best CBD oil products for such a condition.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Compare the Best CBD Oil for Carpal Tunnel Syndrome in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5

Best CBD Oil for Carpal Tunnel Syndrome

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How CBD May Help With Carpal Tunnel Syndrome 

CBD (cannabidiol), a cannabinoid found in the cannabis plant, has been shown to have a broad spectrum of actions, including analgesic, neuroprotective, anti-epileptic, anti-inflammatory, antipsychotic, and anti-anxiety effects(1-2)

CBD and other cannabinoids like THC (tetrahydrocannabinol) work with the ECS (endocannabinoid system) to maintain homeostasis(3). Unlike THC, cannabidiol does not give users a euphoric high(4)

Meanwhile, homeostasis is a process by which living organisms maintain stability while adjusting to environmental conditions(5).

The ECS regulates numerous bodily functions, including inflammatory and immune responses and pain control(6). It consists of cannabinoid receptors 1 and 2 (CB1 and CB2), endocannabinoids, and enzymes(7)

CB1 receptors play a significant role in pain sensation, while CB2 receptors stimulate an anti-inflammatory response(8). Although CBD has a little binding affinity with these receptors, the compound may antagonize them in the presence of THC

CBD may reduce the efficacy and potency of THC and also regulate the perception of pain(9)

Although no specific study has been done on CBD for CTS (carpal tunnel syndrome), several research studies have been done on cannabidiol for pain and neuropathy

Neuropathy refers to the dysfunction or damage of one or more nerves that usually leads to numbness, muscle weakness, tingling, and pain in a particular area(10)

Meanwhile, the carpal tunnel is a narrow passageway surrounded by ligaments and bones on the palm side of the hand. 

CTS is experienced when the median nerve is compressed(11). The median nerve is the primary nerve of the front of the forearm.

Carpal tunnel syndrome involves nerve pain(12).  

Benefits of Using CBD for Carpal Tunnel Syndrome

A randomized controlled trial from the journal Current Pharmaceutical Biotechnology examined the effectiveness of topical CBD oil in the symptomatic relief of peripheral neuropathy of the lower extremities(13)

The study involved 29 patients with symptomatic peripheral neuropathy. About 15 patients were randomized to the CBD group, receiving 250mg of CBD. On the other hand, 14 participants were randomized to the placebo group. 

The researchers measured pain biweekly through the NPS (neuropathic pain scale) to assess the mean change from baseline to the end of the treatment period.

The results showed that the transdermal application of CBD oil may achieve significant improvement in pain and other sensations in patients with peripheral neuropathy(14)

Transdermal application is an administration route wherein active ingredients are delivered across the skin for systematic distribution. 

A 2018 study from Current Pain and Headache Reports suggested that medical cannabis may be as effective and tolerable as current neuropathic agents(15)

Cannabis refers to products from the Cannabis sativa plant(16). Aside from CBD and THC, more than 100 cannabinoids may be found in the cannabis plant. 

CBD may also be effective in chemotherapy-related neuropathy(17)

An experimental study from the British Journal of Pharmacology examined the combined effects of THC and CBD in a murine model of chemotherapy-induced neuropathic pain(18)

The results indicated that CBD may help prevent the development of chemotherapy-induced peripheral neuropathy, and its clinical usage may be enhanced by co-administration of THC in low doses(19)

A 2020 study from the journal Frontiers in Pharmacology hypothesized that the potential pain-relieving effects of CBD are condition-specific(20)

Hence, CBD may help with some types of chronic pain. However, the non-psychoactive compound may not provide universal pain relief

A 2019 review from Current Opinion in Rheumatology examined how cannabinoids like CBD may help with rheumatoid arthritis(21).

The study mentioned that CBD may have antiarthritic effects independent of cannabinoid receptors(22).  

Rheumatoid arthritis is a type of autoimmune disease that can affect your joints and damage a wide variety of body systems and organs, including the lungs, heart, blood vessels, and eyes(23)

Carpal tunnel syndrome is common among people with rheumatoid arthritis(24). Hence, using CBD may benefit those who have CTS. 

However, a direct study examining the efficacy and therapeutic benefits of CBD on carpal tunnel syndrome is still warranted.  

How to Take CBD Oil Products for Carpal Tunnel Syndrome

For carpal tunnel syndrome, you may take CBD topicals like lotions, salves, and creams. Topicals are applied to the skin for localized relief. 

CBD has been shown to help with inflammation and muscle tightness when applied topically(25).  

When CBD and other cannabinoids are applied to the skin, they do not enter the bloodstream or become available to the body as a whole(26)

Instead, CB2 receptors in the skin absorb these cannabinoids. They are then absorbed locally to reduce inflammation and provide pain relief in a specific area(27).  

A wrist fracture may narrow the carpal tunnel and irritate the nerves. Swelling and inflammation triggered by rheumatoid arthritis may also trigger CTS(28)

Therefore, CBD topicals may help with carpal tunnel syndrome. Other CBD forms available in the market include CBD tinctures, vapes, and edibles, like gummies

CBD Dosage for Carpal Tunnel Syndrome 

The FDA (Food and Drug Administration) does not recognize CBD as a medical treatment for carpal tunnel syndrome. Therefore, there is no standard CBD dosage for CTS. 

However, a review from the journal Current Drug Safety suggested that chronic use and high doses of CBD up to 1,500mg daily are well tolerated in humans(29)

Additionally, doses between 10mg and 100mg of CBD per day may help with pain, inflammation, and autoimmune disorders(30)

Rheumatoid arthritis is an autoimmune disease, and many people with such a condition also have carpal tunnel syndrome(31)

Still, it is best to talk with a healthcare professional experienced in cannabis use for accurate dosing. 

How Long Does CBD Take to Help Carpal Tunnel Syndrome?

How long CBD takes to help with carpal tunnel syndrome depends on the administration method and several other factors, such as CBD potency and the potential user’s body weight and metabolism. 

Inhaling CBD using vape pens is the quickest method to benefit from the effect of CBD(32). Smoking or vaping CBD usually takes effect within 2 to 15 minutes(33)

However, extra caution is necessary when using e-cigarettes. Remember that vaping may damage the lungs(34)

Meanwhile, CBD topical products typically take effect within 15 to 30 minutes(35)

The content of topical products is not absorbed into the whole body compared to other forms like vapes(36)

Nonetheless, that could make these products safer, considering how little is known about the long-term safety of CBD(37)

A 2020 randomized controlled trial demonstrated that patients with peripheral neuropathy may significantly improve pain and other sensations through the transdermal application of CBD oil(38)

Transdermal drug delivery or TDD is a painless way of delivering substances systematically by applying a drug formulation onto healthy skin(39)

Transdermal patches and gels usually take effect within 15 to 30 minutes(40)

How Long Will CBD Help With Carpal Tunnel Syndrome?

How long CBD helps with carpal tunnel syndrome depends on its bioavailability. 

Bioavailability is the extent to which a specific substance becomes entirely available to its intended biological destinations(41).

 If you have carpal tunnel syndrome, you may feel numbness, pain, and general weakness in your hand and wrist. Some individuals may explore trying CBD topicals to help with such a condition. 

When CBD is applied to the skin, it does not go into the bloodstream or become entirely available to the body. Therefore, its bioavailability is zero(42)

Meanwhile, the bioavailability of CBD via vaping is between 17% and 44%(43)

How to Choose the Best CBD Oil Product for Carpal Tunnel Syndrome 

Choosing a high-quality CBD product depends on various factors, including your personal preference, the severity of your condition, or the form of CBD you prefer

Here are the pertinent factors to consider when choosing the best CBD oil for carpal tunnel syndrome and overall wellness

CBD Oil Extracts

A full-spectrum CBD oil product contains all compounds of the cannabis plant, including flavonoids, terpenes, essential oils, and other cannabinoids(44). Furthermore, the THC concentration is not more than 0.3%.  

Terpenes are the natural oils that give cannabis aroma, color, and flavor. It is believed that terpenes have a synergistic ability to work with cannabinoids, like CBD and THC(45)

When ingested or inhaled, terpenes may assist the cannabinoids as they penetrate the blood-brain barrier(46). These natural oils may also influence neurotransmitters in the brain, affecting serotonin and dopamine production. 

Serotonin is the primary hormone that stabilizes mood. Meanwhile, dopamine is a neurotransmitter that acts as a chemical messenger between neurons. 

On the other hand, flavonoids are active compounds found in cannabis. They contribute to cannabis’ pigmentation, aroma, and flavor, possibly through synergistic relationships with other active compounds like terpenes(47)

Broad-spectrum CBD oil is similar to the full-spectrum variant. The only difference is that broad-spectrum CBD is nearly THC-free(48). Meanwhile, CBD isolates are made of pure CBD

A study from the journal Frontiers in Plant Science hypothesized that the entourage effect produced through the consumption of full-spectrum hemp extracts may have better health benefits than pure CBD(49).  

The entourage effect is the symbiosis of pharmacological effects that occur through the interaction of terpenoids, cannabinoids, and other compounds found in the whole cannabis plant(50)

Source of Hemp 

For hemp-derived CBD products, it is crucial to determine the source of hemp. 

Some CBD products may have irritants and other contaminants that may put your health at risk.

Hence, ensure to opt for a CBD brand that is transparent with its farming practices. The CBD company must provide sufficient information about its hemp products.

If possible, you should look for organic hemp or non-GMO CBD products

Extraction Methods

There are different extraction methods used to obtain cannabis oil and hemp extracts. These techniques include the use of natural solvents and ethanol, steam distillation, and carbon dioxide (CO2) extraction. 

A frequently used technique is carbon dioxide extraction. In this method, compressed CO2 is utilized as the extraction solvent(51)

Meanwhile, extraction methods using hexane or butane may leave harmful residues(52)

Third-Party Lab Testing 

Another pertinent factor to consider when selecting the best CBD product is whether a CBD company enlists the services of a third-party lab

The CBD brand you choose must provide lab reports or COAs (certificates of analysis) of all their products on their official website. These reports are essential to confirm that the CBD products meet the specifications advertised on their labels. 

CBD and THC Content 

Before purchasing any CBD product, you must first know the amount of CBD and THC in it. The dose of most CBD products is expressed in milligrams (mg). 

Thus, make sure to check the COA to determine the accuracy of the declared CBD potency and concentration.

Carrier Oils  

After extracting cannabidiol from the hemp plant, CBD manufacturers infuse the compound into a carrier oil to enhance a product’s bioavailability.

The most commonly used carrier oils are hempseed and coconut oil. Most people use hemp oil and hempseed oil interchangeably. However, they have significant variations. 

Hemp oil is an essential oil that comes from the leaves and flowers of hemp plants. Meanwhile, hempseed oil is made from the pressed seeds of hemp plants. 

Hempseed oil does not contain CBD. Still, it is rich in fatty acids and nutrients(53)

The CBD Brand’s Reputation

  There are various CBD products available on the market, especially online. Therefore, verifying whether a specific CBD brand is authorized to manufacture and sell CBD items is crucial.

Research the CBD company to know if it is a trusted brand. Visit its official website, social media platforms, and read customer reviews to get more insights into the brand and its products.

The Possible Side Effects and Risks of Using CBD for Carpal Tunnel Syndrome 

According to the WHO (World Health Organization), CBD is relatively safe and well tolerated in humans and animals(54). Still, CBD may induce some risks and minor side effects, including(55):  

  • Diarrhea
  • Dry mouth
  • Reduced appetite
  • Drowsiness
  • Fatigue 

Another cause for concern is how CBD may interact with other medications. 

The cytochrome P450 group is a family of liver enzymes that metabolize approximately 60% of the pharmaceutical drugs people consume(56)

At high doses, CBD may inhibit the activity of these enzymes, increasing the duration of action and effect of prescription drugs metabolized by the cytochrome P450(57)

NSAIDs (nonsteroidal anti-inflammatory drugs) use the cytochrome P450 enzyme system(58)

For instance, over-the-counter painkillers like ibuprofen may help relieve pain from carpal tunnel syndrome for a short period(59)

However, make sure to talk with your healthcare provider if you are considering using CBD simultaneously with any prescription drugs to manage symptoms of carpal tunnel syndrome. This way, experts can advise you regarding possible drug interactions. 

Legality of CBD

The U.S. Congress ratified the 2018 Farm Bill, decriminalizing the commercial use of industrial hemp and products obtained from hemp plants(60)

The bill states that Cannabis sativa L. and other derivatives of cannabis with no more than 0.3% THC content on a dry weight basis are considered legal under federal law(61)

The Federal Comprehensive Drug Abuse Prevention and Control Act of 1970 created a drug schedule to classify substances into five categories based on the potential for drug abuse and possible medical use of various substances(62).

Some states have passed individual laws allowing recreational and medical marijuana(63). Nevertheless, these state laws do not change the fact that, under federal law, marijuana is still listed as a Schedule I drug. 

Substances listed as Schedule I drugs have a high abuse potential with acceptable medical use. For this reason, medications under this category may not be dispensed, prescribed, or administered under federal law. 

Rules and regulations regarding medical cannabis may be confusing. Hence, consumers should familiarize themselves with various state laws. 

Before, hemp and CBD oil were illegal in South Dakota(64). However, on October 25, 2021, the South Dakota Department of Health formed medical cannabis establishments(65)

Mount Rushmore State aims to deliver a safe and responsible medical cannabis program. Hence, Governor Noem and the South Dakota Department of Health allowed the printing and issuing of the first medical cannabis patient cards on November 18, 2021(66).

Product Frequently
Asked Questions

  • How can CBD help with carpal tunnel syndrome?

    No specific scientific research has been conducted on CBD for carpal tunnel syndrome. However, studies have taken place relating to cannabidiol for pain and neuropathy (nerve damage). 

    CBD has purported anti-inflammatory and pain-relieving properties(67-68). Hence, CBD’s potential health benefits may help manage symptoms of carpal tunnel syndrome

    Carpal tunnel syndrome usually involves nerve pain(69).

  • What evidence or research exists to say that CBD helps with carpal tunnel syndrome?

    There is no evidence suggesting that CBD may help with carpal tunnel syndrome

     

    However, a 2020 study suggested that the transdermal application of CBD oil may significantly improve pain and other sensations in patients with peripheral neuropathy(70)

    Transdermal drug delivery is when substances are administered into the skin for systematic distribution.

  • Is there any evidence that CBD can make carpal tunnel syndrome worse?

    No evidence exists stating that CBD can make carpal tunnel syndrome worse. 

    CBD is generally safe for use and well tolerated in humans and animals(71). Still, it is best to consult your healthcare provider if you are considering using CBD for carpal tunnel syndrome

    This way, they can advise you about risks and other causes for concern like drug interactions.

  • Will CBD interact with any current medication I may be taking for carpal tunnel syndrome?

    Yes. CBD may interact with NSAIDs(72). NSAIDs like ibuprofen may help relieve pain from carpal tunnel syndrome for a short time(73)

    For this reason, if you are taking ibuprofen or any painkillers for carpal tunnel syndrome, ensure to ask your healthcare provider first before you use CBD.   

  • Are there other treatments I should consider alongside CBD to help with carpal tunnel syndrome?

    If your CTS is diagnosed early, taking NSAIDs and observing nonsurgical practices like using a wrist splint may help cure your carpal tunnel syndrome(74)

    Your healthcare provider may also inject steroids into your carpal tunnel (corticosteroids) to relieve pain(75)

    However, NSAIDs and steroids may interact with CBD(76). Therefore, you should talk to your clinician if you consider other treatments alongside CBD to help with carpal tunnel syndrome.

  • Can I fail a drug test if I use CBD for carpal tunnel syndrome?

    CBD is non-psychoactive, so it will not cause a euphoric effect(77). Still, most CBD products contain traces of THC that may build up in the body when taken regularly in a span of four to six days(78)

    An increased THC level in the bloodstream may result in a positive drug test. 

  • What is the dosage for carpal tunnel syndrome?

    The FDA has not approved CBD as a medical treatment for carpal tunnel syndrome. Therefore, there is no standard CBD dosage for CTS. 

    However, doses between 10mg and 100mg of CBD per day may help with pain, inflammation, and autoimmune disorders(79). Hence, these doses may relieve pain and inflammation from CTS. 

    Still, it is best to consult a physician experienced in cannabis use for accurate dosing. 

  • What are some side effects of CBD for carpal tunnel syndrome?

    Generally, minor side effects of CBD include fatigue and drowsiness(80).


  1. Cannabis (Marijuana) and Cannabinoids: What You Need To Know
    https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
  2. Cannabidiol and Other Non-Psychoactive Cannabinoids for Prevention and Treatment of Gastrointestinal Disorders: Useful Nutraceuticals?
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246936/
  3. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  4. Immune Responses Regulated by Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/
  5. Homeostasis: The Underappreciated and Far Too Often Ignored Central Organizing Principle of Physiology
    https://www.frontiersin.org/articles/10.3389/fphys.2020.00200/full
  6. The Endocannabinoid System: Essential and Mysterious
    https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
  7. An Introduction to the Endogenous Cannabinoid System
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789136/
  8. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  9. Ibid.
  10. Neuropathy (Peripheral Neuropathy)
    https://my.clevelandclinic.org/health/diseases/14737-neuropathy
  11. Carpal Tunnel Syndrome
    https://www.mayoclinic.org/diseases-conditions/carpal-tunnel-syndrome/symptoms-causes/syc20355603#:~:text=Carpal%20tunnel%20syndrome%20is%20caused,in%20the%20hand%20and%20arm.
  12. Ibid.
  13. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
    https://pubmed.ncbi.nlm.nih.gov/31793418/
  14. Ibid.
  15. Medical Cannabis for Neuropathic Pain
    https://pubmed.ncbi.nlm.nih.gov/29388063/
  16. Cannabis (Marijuana) and Cannabinoids: What You Need To Know
    https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know#:~:text=The%20word%20%E2%80%9Ccannabis%E2%80%9D%20refers%20to,amounts%20of%20tetrahydrocannabinol%20(THC).
  17. Single and Combined Effects of Δ9-Tetrahydrocannabinol and Cannabidiol in a Mouse Model of Chemotherapy-Induced Neuropathic Pain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554313/
  18. Ibid.
  19. Ibid.
  20. A Balanced Approach for Cannabidiol Use in Chronic Pain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204604/
  21. Joints for Joints: Cannabinoids in the Treatment of Rheumatoid Arthritis
    https://pubmed.ncbi.nlm.nih.gov/30920973/
  22. Ibid.
  23. Rheumatoid Arthritis
    https://www.mayoclinic.org/diseases-conditions/rheumatoid-arthritis/symptoms-causes/syc-20353648
  24. Rheumatoid Arthritis
    https://www.nhs.uk/conditions/rheumatoid-arthritis/complications/#:~:text=Carpal%20tunnel%20syndrome%20is%20a,numbness
  25. Healing With CBD, page. 210.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  26. Ibid.
  27. Ibid.
  28. Carpal Tunnel Syndrome
    https://www.mayoclinic.org/diseases-conditions/carpal-tunnel-syndrome/symptoms-causes/syc-20355603
  29. Safety and Side Effects of Cannabidiol, a Cannabis Sativa Constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  30. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  31. Rheumatoid Arthritis
    https://www.nhs.uk/conditions/rheumatoid-arthritis/complications/#:~:text=Carpal%20tunnel%20syndrome%20is%20a,numbness
  32. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  33. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  34. Is It Safe to Vape CBD?
    https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/
  35. Healing With CBD, page. 193.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  36. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  37. Ibid.
  38. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
    https://pubmed.ncbi.nlm.nih.gov/31793418/
  39. Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the stratum corneum
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/#:~:text=2.-,Transdermal%20Drug%20Delivery%20(TDD),accumulation%20in%20the%20dermal%20layer.
  40. Healing With CBD, page 194.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  41. Drug Bioavailability
    https://www.ncbi.nlm.nih.gov/books/NBK557852/
  42. Healing With CBD, page 210.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  43. Healing With CBD, page. 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  44. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  45. Healing With CBD, page. 94.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  46. Healing With CBD, page 95.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  47. Healing With CBD, page. 282.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  48. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  49. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/
  50. CBD: A Patient’s Guide to Medicinal Cannabis, page 468.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  51. Understanding Dabs: Contamination Concerns of Cannabis Concentrates and Cannabinoid Transfer During the Act of Dabbing
    https://www.jstage.jst.go.jp/article/jts/40/6/40_797/_pdf/-char/en
  52. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  53. Hemp Seed Oil Properties
    https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
  54. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  55. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq20446700#:~:text=CBD%20use%20also%20carries%20some,taking%2C%20such%20as%20blood%20thinners.
  56. Healing With CBD, pages 114-115.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  57. Ibid.
  58. Healing With CBD, page 116.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  59. Carpal Tunnel Syndrome
    https://www.mayoclinic.org/diseases-conditions/carpal-tunnel-syndrome/diagnosis-treatment/drc-20355608
  60. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  61. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  62. The Federal Controlled Substances Act: Schedules and Pharmacy Registration
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839489/#:~:text=The%20Federal%20Comprehensive%20Drug%20Abuse,effective%20on%20May%201%2C%201971.&text=The%20goal%20of%20the%20Controlled,and%20dispensing%20of%20controlled%20substances.
  63. Ibid.
  64. Attorney General Ravnsborg Clarifies Questions Regarding Industrial Hemp and CBD (Cannabidiol) Oil
    https://atg.sd.gov/OurOffice/Media/pressreleasesdetail.aspx?id=2167
  65. Medical Cannabis in South Dakota
    https://medcannabis.sd.gov/events-all.aspx
  66. Ibid.
  67. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  68. Research Shows Pain-Relieving Effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  69. Carpal Tunnel Syndrome
    https://www.mayoclinic.org/diseases-conditions/carpal-tunnel-syndrome/symptoms-causes/syc-20355603#:~:text=Carpal%20tunnel%20syndrome%20is%20caused,in%20the%20hand%20and%20arm.
  70. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
    https://pubmed.ncbi.nlm.nih.gov/31793418/
  71. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  72. Healing With CBD, page 116.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  73. Carpal Tunnel Syndrome
    https://www.mayoclinic.org/diseases-conditions/carpal-tunnel-syndrome/diagnosis-treatment/drc-20355608
  74. Ibid.
  75. Ibid.
  76. Healing With CBD, pages 115-116.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  77. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  78. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  79. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  80. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq20446700#:~:text=CBD%20use%20also%20carries%20some,taking%2C%20such%20as%20blood%20thinners.
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