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Best CBD Oil for Bone Growth

Are you looking for a natural option to help with bone development? Read on to know the effects of CBD on bone growth and overall bone health

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil


3.7 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the best CBD for Bone Growth in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

1.0 out of 5

5.0 out of 5

Best CBD Oil for Bone Growth

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score
3.5
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes  Shipping not specified on website
 More flavors to choose from  3rd party lab result is currently not available on website
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Pros
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes
 More flavors to choose from
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Cons
 Shipping not specified on website
 3rd party lab result is currently not available on website
Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With Bone Growth

Recent scientific data suggest that the ECS (endocannabinoid system) may influence bone metabolism(1). Bone metabolism refers to the continual production and degradation of bone tissue. 

The ECS is a neuromodulatory system responsible for bodily homeostasis or balance. It comprises cannabinoid receptors like CB1 and CB2 receptors, enzymes, and endocannabinoids. 

Although cannabinoid receptors are involved in bone mass regulation, CB2 receptors are more highly expressed in bone cells, including osteoclasts and osteoblasts(2).

Osteoblasts are bone-forming cells, while osteoclasts are bone-resorbing cells. Both cells produce anandamide(3)

Anandamide, the first discovered endocannabinoid, is a fatty acid neurotransmitter. It affects bone cells by binding directly to CB2 receptors(4)

Plant-based cannabinoids (phytocannabinoids), like CBD and THC, may mimic the actions of endocannabinoids like anandamide(5)

CBD (cannabidiol) and THC (tetrahydrocannabinol) are the principal cannabinoids naturally present in the resin of the cannabis plant

Unlike THC, the psychoactive compound of cannabis, CBD has been demonstrated to have a low binding affinity for CB1 and CB2 receptors(6)

However, CB1 receptors found within the pain pathways of the brain and spinal cord may affect CBD-induced analgesia (loss of pain perception)(7)

A study using a murine model of bone cancer suggested that a decrease in anandamide signaling contributes to pain(8).  

CBD may enhance anandamide signaling(9). In addition, the non-psychoactive compound may provide pain relief(10)

GPR55, or G protein-coupled receptor, has been implicated as a new cannabinoid receptor(11)

A study from the Proceedings of the National Academy of Sciences of the United States of America showed that blocking GPR55 in adult male mice may reduce osteoclast activity and increase bone mass(12)

Antagonists are substances that block receptors. As a GPR55 antagonist, CBD may inhibit bone resorption(13). Bone resorption refers to the destruction of bone tissues that promotes bone loss

Studies regarding CBD’s potential therapeutic effects and activity in the skeletal endocannabinoid system are still in their infancy. 

Still, the available scientific data may be a good starting point for researchers who want to explore how CBD may help with bone development, growth, and overall bone health.   

Benefits of Using CBD for Bone Growth

Research involving a rat model hypothesized that CBD may help with intervertebral disc degeneration(14).

Intervertebral disc disease is a painful condition characterized by the degeneration (breakdown) of one or more discs, separating the bones of the vertebrae (spine)(15)

In numerous inflammatory-induced chronic pain models, cannabinoids like CBD may exert anti-inflammatory and analgesic effects(16)

A study from Immunity and Ageing suggested that inflammation may significantly affect bone turnover, inducing osteoporosis(17).  

Osteoporosis makes bones brittle and weak. Bone fractures are the most severe complications of osteoporosis(18)

Tel Aviv University researchers hypothesized that the non-psychotropic compound of cannabis may help with bone fractures(19).  

Dr. Yankel Gabet, the study’s lead researcher, said that CBD alone may strengthen bone during the healing process(20)

Meanwhile, a review from the Current Osteoporosis Report mentioned that CBD may enhance fracture healing in rats(21)

A study from the Caspian Journal of International Medicine suggested that individuals with rheumatoid arthritis are at increased risk of developing osteoporosis(22).  

Rheumatoid arthritis is characterized by inflammation and joint pain

A 2020 study from Cell Death and Disease hypothesized that CBD may be a potential adjuvant treatment in rheumatoid arthritis(23). An adjuvant is a drug that enhances the immune system’s response to antigens. 

On the other hand, a 2021 online survey showed that individuals with fibromyalgia were substituting CBD for opioids and other conventional pain medications(24)

Fibromyalgia causes widespread musculoskeletal pain. Due to impaired mobility, individuals with fibromyalgia may have a decreased bone density. Hence, these patients may also be at increased risk of developing osteoporosis(25)

Opioids are potent analgesics. However, opioid consumption may increase fracture risks(26). In addition, chronic opioid use is a recognized risk factor for osteoporosis(27)

Meanwhile, CBD has purported analgesic and anti-inflammatory properties(28). It also has a good safety profile(29)

More importantly, CBD is believed to help with bone healing(30). In addition, CBD may influence calcium mobilization and increase intracellular (occurring within a cell) calcium levels(31). Calcium is a mineral typically associated with healthy teeth and bones. 

The putative usefulness of CBD for bone health is plausible considering the compound’s pharmacology. 

However, most studies are inconclusive, and some are conducted on animals. Hence, validation in longitudinal clinical trials is needed to elucidate the benefits of CBD for bone health and whether CBD products like CBD oil are good for bone growth and overall wellness. 

How to Take CBD Oil for Bone Growth

Inhaling CBD through vape pens is the quickest method to benefit from the effects of the compound(32). The onset time of CBD via the inhalation route is between 2 and 15 minutes, and its effect usually lasts from 2 to 4 hours(33)

However, most lung injury cases in the U.S. are associated with vaping(34)

Meanwhile, the sublingual (under the tongue) method also provides rapid effects without exposing the lungs to tar and heat(35). This route also lets you avoid dealing with the smell, smoky taste, dry mouth, and other issues such as coughing and throat irritation.

The onset time of CBD via the sublingual route is between 15 and 30 minutes, and its effect usually lasts from 2 to 4 hours(36)

CBD Dosage for Bone Growth

The FDA (Food and Drug Administration) does not endorse CBD as a supplement to improve bone health. For this reason, there is no standard CBD dosage for bone development and growth.

However, an animal study from the Journal of Bone and Mineral Research suggested that CBD alone may be sufficiently effective in enhancing fracture healing(37)

The researchers administered CBD and THC individually (5mg per kilogram of body weight each day) via intraperitoneal injection to rats with mid-femoral fractures(38).

Femoral fractures refer to broken thigh bones. Through an intraperitoneal injection a substance is administered through the peritoneum, a large membrane in the abdominal cavity that supports internal organs.  

In humans, symptoms of femoral fractures include severe pain(39). Doses between 10mg and 100mg of CBD daily may help with the pain(40)

Still, it is best to talk with your healthcare provider to determine the proper CBD dosage for your specific health condition

How Long Does CBD Take to Help With Bone Growth? 

How long CBD takes effect to help with bone development and growth depends on several factors, including the administration route, individual body weight, the type of CBD, and potency. 

If you take CBD via the inhalation route, you will feel its effects within 2 to 15 minutes(41). Nevertheless, you should be cautious because vaping may damage your lungs(42)

On the other hand, if you choose to take CBD under the tongue, you will feel its effect within 15 to 30 minutes(43).  

How Long Will CBD Help With Bone Growth?

After CBD starts to help, how long it will last depends on its bioavailability and half-life.

Bioavailability is the extent to which a particular substance becomes entirely available to its intended biological destinations. 

Half-life refers to the length of time necessary for the concentration of a specific drug to decrease by half of its starting dose.

A 2018 systematic review published in Frontiers in Pharmacology mentioned that CBD’s bioavailability following smoking is 31%, and its half-life is 31 hours(44)

On the other hand, the bioavailability of CBD via the sublingual route is between 6% and 20%(45). Additionally, CBD is reported to have a half-life between 1.4 and 10.9 hours following oromucosal spray(46) 

How to Shop for CBD Oil Products for Bone Growth

Various CBD brands promise to offer the best CBD oil products for bone development and growth. 

Below are a few pertinent factors to consider when looking for a high-quality CBD product

Hemp Extracts

Full-spectrum CBD oil contains all compounds of the cannabis plant, including CBD and other cannabinoids, essential oils, flavonoids, and terpenes.

Flavonoids are active compounds found in cannabis that are believed to have antioxidant, anti-inflammatory, and antiviral actions(47)

On the other hand, terpenes are the components of essential oils responsible for the aroma of cannabis(48)

Full-spectrum CBD oil has no more than 0.3% THC concentration. 

Meanwhile, broad-spectrum CBD oil also contains all of the natural compounds of cannabis. However, this CBD variant is THC-free. 

CBD isolates are made of pure CBD.

Ingredients 

If possible, always opt for CBD products made from U.S.-grown hemp. Make sure to choose CBD companies that source their plant materials from non-GMO hemp cultivated through natural farming.  

Extraction Method 

Carbon dioxide, ethanol, or solvent extraction is preferred to create a safe CBD product(49). Meanwhile, extraction techniques utilizing hexane or butane may leave harmful residues like pesticides.

Types of CBD Products 

Most CBD-derived products available in the market are:

  • Vapes
  • CBD oils and CBD tinctures 
  • Edibles like CBD gummies and capsules
  • Topicals like CBD creams, salves, and lotions

The type of CBD products you choose will depend on your lifestyle, preferences, specific conditions, and expected CBD effects. 

If you want to know which CBD form is the most effective for your needs and condition, consult a doctor versed in cannabis use for recommendations. 

Third-Party Lab Testing

The best way to check whether a CBD product contains what the brand says it does is to look at the lab reports. The lab test reports must be up-to-date and come from a trusted third-party laboratory.  

Carrier Oils 

The most commonly utilized carrier oils are MCT (medium-chain triglycerides) oil, coconut oil, and hempseed oil. 

Hempseed oil is packed with nutrients and fatty acids, although it does not contain cannabidiol(50)

The Risks and Side Effects of Using CBD for Bone Growth

  Generally, the commonly reported side effects of using CBD include(51)

  • Low blood pressure
  • Dry mouth
  • Drowsiness

Does CBD Have a Good Safety Profile? 

Aside from potential risks and side effects, another cause for concern is the lack of regulation of CBD products marketed as supplements(52)

The FDA has only seen limited scientific data about CBD’s safety(53). Hence, the agency will continuously update the public as it learns more about cannabidiol

CBD’s safety profile has been shown in several ways(54). A study suggested that chronic use and high doses of up to 1,500 mg of CBD daily are well tolerated in humans(55)

Still, some knowledge gaps should be closed by further clinical trials for a completely well-tested pharmaceutical compound. 

Legality of CBD

Rules and regulations regarding CBD and medicinal cannabis vary from state to state.  

For example, Governor Eric Holcomb of Indiana signed HB1148 on April 27, 2017(56). The bill allows the use of CBD products with at least 5% CBD concentration and no more than 0.3% THC concentration for treatment-resistant epilepsy

Meanwhile, Colorado permits recreational and medical marijuana use. The local government decriminalized the use of marijuana by passing Amendment 64 to the Colorado Constitution in November 2012(57).  

Product Frequently
Asked Questions


  1. Bones and Joints: The Effects of Cannabinoids on the Skeleton https://academic.oup.com/jcem/article/104/10/4683/5523890
  2. Ibid.
  3. Cannabinoid Receptors and the Regulation of Bone Mass https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219540/
  4. Ibid.
  5. The Endocannabinoid System, Our Universal Regulator https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  6. Cannabidiol Displays Unexpectedly High Potency as an Antagonist of CB1 and CB2 Receptor Agonists In Vitro https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189767/
  7. Cannabidiol  https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  8. A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628759/
  9. Cannabidiol Enhances Anandamide Signaling and Alleviates Psychotic Symptoms of Schizophrenia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316151/
  10. Research Shows Pain-Relieving Effects of CBD https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  11. GPR55 Is a Cannabinoid Receptor That Increases Intracellular Calcium and Inhibits M Current https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268199/
  12. The Putative Cannabinoid Receptor GPR55 Affects Osteoclast Function In Vitro and Bone Mass In Vivo https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/
  13. Ibid.
  14. Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113161
  15. Intervertebral Disc Disease https://medlineplus.gov/genetics/condition/intervertebral-disc-disease/
  16. Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700528/
  17. Osteoporosis, Inflammation and Ageing https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308846/
  18. Osteoporosis https://www.mayoclinic.org/diseases-conditions/osteoporosis/symptoms-causes/syc-20351968
  19. No Bones About It: Cannabis May Be Used to Treat Fractureshttps://www.sciencedaily.com/releases/2015/07/150716124359.htm
  20. Ibid.
  21. The Cannabinoids Effect on Bone Formation and Bone Healing https://pubmed.ncbi.nlm.nih.gov/32705630/
  22. Rheumatoid Arthritis and Osteoporosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097988/
  23. Cannabidiol (CBD): A Killer for Inflammatory Rheumatoid Arthritis Synovial Fibroblasts https://www.nature.com/articles/s41419-020-02892-1
  24. Substituting Cannabidiol for Opioids and Pain Medications Among Individuals With Fibromyalgia: A Large Online Survey https://pubmed.ncbi.nlm.nih.gov/33992787/
  25. Bone Health in Patients With Fibromyalgia https://academic.oup.com/rheumatology/article/42/10/1202/1784907
  26. Non-analgesic Effects of Opioids: The Interaction of Opioids With Bone and Joints https://pubmed.ncbi.nlm.nih.gov/22747537/
  27. Ibid.
  28. Cannabidiol https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  29. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  30. The Cannabinoids Effect on Bone Formation and Bone Healing https://pubmed.ncbi.nlm.nih.gov/32705630/
  31. Cannabidiol (CBD): A Killer for Inflammatory Rheumatoid Arthritis Synovial Fibroblasts https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463000/
  32. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It? https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  33. Healing With CBD, page 190. https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  34. Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html
  35. CBD: A Patient’s Guide to Medicinal Cannabis, page 105. https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  36. Healing With CBD, page 192. https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  37. Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts https://asbmr.onlinelibrary.wiley.com/doi/10.1002/jbmr.2513
  38. Ibid.
  39. Femur Shaft Fractures (Broken Thighbone) https://orthoinfo.aaos.org/en/diseases–conditions/femur-shaft-fractures-broken-thighbone/
  40. CBD: A Patient’s Guide to Medicinal Cannabis, page 129. https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  41. Healing With CBD, page 190. https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  42. Is It Safe to Vape CBD? https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/
  43. Healing With CBD, page 192. https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  44. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  45. Healing With CBD, page 192. https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  46. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  47. Flavonoids As Antioxidants https://pubmed.ncbi.nlm.nih.gov/10924197/
  48. The Cannabis Terpenes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763918/
  49. Cannabidiol Primer for Healthcare Professionals https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  50. Hemp Seed Oil Properties https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
  51. CBD: What You Need to Know Before You Try https://www.cedars-sinai.org/blog/cbd-safe.html
  52. Ibid.
  53. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
  54. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  55. Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent https://pubmed.ncbi.nlm.nih.gov/22129319/
  56. States With Legal Cannabidiol (CBD) https://medicalmarijuana.procon.org/states-with-legal-cannabidiol-cbd/
  57. Legal Marijuana Use in Coloradohttps://cannabis.colorado.gov/legal-marijuana-use-in-colorado
  58. The Putative Cannabinoid Receptor GPR55 Affects Osteoclast Function In Vitro and Bone Mass In Vivo https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/
  59. No Bones About It: Cannabis May Be Used to Treat Fractures https://www.sciencedaily.com/releases/2015/07/150716124359.htm
  60. Relationship Between Bone Mass And Muscle Weakness In Chronic Neurological Diseases (P3.036) https://n.neurology.org/content/82/10_Supplement/P3.036
  61. Aging Changes in the Bones – Muscles – Joints https://medlineplus.gov/ency/article/004015.htm
  62. What Are the Benefits of CBD — And Is It Safe to Use? https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  63. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  64. Osteoporosis https://www.mayoclinic.org/diseases-conditions/osteoporosis/diagnosis-treatment/drc-20351974
  65. Can You Take CBD and Pass a Drug Test? https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  66. Osteoporosis https://my.clevelandclinic.org/health/diseases/4443-osteoporosis
  67. CBD: A Patient’s Guide to Medicinal Cannabis, page 129. https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  68. Cannabidiol (CBD)-What We Know and What We Don’t https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  69. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
  70. What People With Rheumatoid Arthritis Need To Know About Osteoporosis https://www.bones.nih.gov/health-info/bone/osteoporosis/conditions-behaviors/osteoporosis-ra
  71. Ibid. 
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