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Best CBD for Leishmaniasis

Are you curious about the potential benefits of CBD (cannabidiol) for leishmaniasis symptoms? CBD Clinicals provides pertinent information on the best CBD oil that may help optimize overall wellness.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil


4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil


5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil


5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg


4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg


4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures


4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg


4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil


4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil


3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil


3.5 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the Best CBD for Leishmaniasis in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

5.0 out of 5

5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5

5.0 out of 5

3.5 out of 5

3.0 out of 5

5.0 out of 5

4.5 out of 5

4.5 out of 5

5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5

5.0 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5

4.5 out of 5

3.5 out of 5

5.0 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5

2.5 out of 5

5.0 out of 5

5.0 out of 5

5.0 out of 5

4.5 out of 5

5.0 out of 5

5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5

4.5 out of 5

3.5 out of 5

2.5 out of 5

3.5 out of 5

4.5 out of 5

5.0 out of 5

4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5

2.5 out of 5

3.5 out of 5

5.0 out of 5

5.0 out of 5

4.0 out of 5

1.0 out of 5

5.0 out of 5

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
4.8
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Mid-strength  No other flavors
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Pros
 Mid-strength
 Natural peppermint flavor
 Made from 100% organic and natural ingredients
Cons
 No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural
 Approximately 300 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 300 drops total
Cons
 No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
5.0
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Extra Strength  Tastes bitter
 No artificial flavoring or colors  No THC-free option
 Made from 100% organic and natural ingredients
Pros
 Extra Strength
 No artificial flavoring or colors
 Made from 100% organic and natural ingredients
Cons
 Tastes bitter
 No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Light Spearmint flavor  No other flavor
 Non-THC, Non-detected in drug test
Pros
 Light Spearmint flavor
 Non-THC, Non-detected in drug test
Cons
 No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
4.7
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Various delicious flavors to choose from  cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Pros
 Various delicious flavors to choose from
 Has vegan, organic, and gluten-free ingredients
 Free shipping for this particular product within USA
 World-class customer service team
Cons
 cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 60-Day Satisfaction Guarantee  Dropper is a bit shaky
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
 60-Day Satisfaction Guarantee
 Various strengths
 Oil extracted from aerial plant parts of US grown industrial hemp
 Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
 Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
4.6
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Pure CBD hemp  No other flavors
 All natural  A bit pricey compared to competitors
 Approximately 100 drops total
Pros
 Pure CBD hemp
 All natural
 Approximately 100 drops total
Cons
 No other flavors
 A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
4.4
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Vegan and Gluten free  Does not ship internationally
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Pros
 Vegan and Gluten free
 Has a third-party lab test
 Wide variety of CBD strengths and sizes
Cons
 Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
3.9
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Wide variety of flavors  Incomplete information about the product
 Lab test results are complete  Does not ship to all international countries
 30-day money-back guarantee
Pros
 Wide variety of flavors
 Lab test results are complete
 30-day money-back guarantee
Cons
 Incomplete information about the product
 Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score
3.5
CBDC Evaluation Table/Score
Potency
Purity
Customer Service
Type
Extraction
Absorption
Transparency
Pros Cons
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes  Shipping not specified on website
 More flavors to choose from  3rd party lab result is currently not available on website
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Pros
 Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes
 More flavors to choose from
 Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate
Cons
 Shipping not specified on website
 3rd party lab result is currently not available on website
Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With Leishmaniasis

Leishmaniasis is an infectious disease prevalent in tropical and sub-tropical countries where the proliferation of female phlebotomine sand flies (or sandflies) is high(1).

According to the CDC (Centers for Disease Control and Prevention), a sand fly (or sandfly) infected with the Leishmania parasite acts as a carrier of the disease(2). 

Infected sand flies transfer the parasite to humans through a bite, causing leishmaniasis.

This disease may cause lesions on the skin due to the fly bite. These wounds can slowly grow and eventually become an ulcer or an open sore(3).

The lesions may take approximately 3 to 18 months to heal. For individuals with a healthy immune system and antibodies, the wounds may disappear on their own eventually. However, lesions that do not heal may lead to serious health problems(4).

Other symptoms of leishmaniasis include cough, fever, vomiting, diarrhea, and abdominal discomfort(5).

Research has shown that CBD may contain therapeutic properties that may help manage inflammation, pain, and itchiness (pruritus)(6).

CBD may interact with the ECS or endocannabinoid system that is present throughout the body, such as in the immune system, nervous system, and cardiovascular system(7).

The ECS is composed of cannabinoid receptors, primarily CB1 and CB2, that bind with CBD

CB1 receptors regulate the body’s pain sensations, whereas CB2 receptors play a role in anti-inflammatory responses(8)

Aside from the cannabinoid receptors, the ECS comprises enzymes and endocannabinoids, which are naturally-occurring chemical substances in the body.

Moreover, research has shown that cannabinoids such as CBD and THC (tetrahydrocannabinol) may reduce pro-inflammatory cytokines(9).

Cytokines are proteins that influence the growth of cells that aid the body’s inflammation and immune response. Thus, the study suggests CBD’s anti-inflammatory properties.

Further research is needed on CBD’s potential benefits on leishmaniasis. 

However, the studies mentioned above have shown that the compound may contain analgesic (anti-pain), anti-inflammatory, and antipruritic effects(10)

These properties may be advantageous for individuals trying to manage symptoms of medical conditions like leishmaniasis.

Benefits of Using CBD for Leishmaniasis

A 2020 study has indicated that the topical application of CBD may offer therapeutic benefits for skin disorders like eczema or psoriasis(11).  

Individuals with psoriasis and leishmaniasis may experience skin lesions(12-13).

A study published in the journal Molecules investigated the effects of topical CBD on pediatric patients suffering from a rare skin disorder, epidermolysis bullosa(14).

Epidermolysis bullosa may cause the skin to form blisters.  

The respondents were given CBD topicals in cream, oil, and spray for symptom relief. Researchers noted that CBD may have reduced pain and the formation of blisters, promoting rapid wound healing without any adverse effects(15)

According to a study from the British Journal of Pharmacology, CBD may contain therapeutic properties that may relieve nausea and vomiting of individuals undergoing chemotherapy(16).

Nausea and vomiting are symptoms linked to leishmaniasis(17).

Full-spectrum CBD oil possesses a full range of cannabinoids, terpenes, and flavonoids(18)

Terpenes are the naturally occurring compounds in cannabis that provide distinctive aromas and flavors(19).

One of the terpenes in cannabis plants is pinene. They are classified as alpha-pinene and beta-pinene. The alpha variant is naturally abundant in cannabis(20).

A study in the Journal of Ethnopharmacology examined the impact of Syzygium cumini essential oil and its primary component, α-pinene, on leishmania in mice and in vitro(21).

Syzygium cumini, commonly called “jambolão” in Brazil, is a plant that is widely used in folk medicine to counteract leishmaniasis, inflammation, ulcers, and diabetes(22)

The research concluded that Syzygium cumini, along with alpha-pinene, contains antimicrobial properties against bacteria and parasites such as leishmania. In addition, the plant has significant anti-leishmanial activity(23).

The previously mentioned studies highlight the therapeutic benefits of cannabidiol and pinene, an essential oil found in cannabis. 

These benefits may result in a high interest in public health due to cannabis plants’ potential to help alleviate symptoms of leishmaniasis.

How to Use CBD Oil for Leishmaniasis

CBD Topicals

If the infection is on the skin, using a topical CBD product is advisable. 

CBD topicals such as creams and salves are applied directly to an affected area for localized relief from pain, inflammation, and itching(24).

Topically applied cannabinoids do not enter the bloodstream. CB2 receptors located on the skin instead absorb the cannabinoids, providing pain relief and reducing inflammation(25).

CBD Tinctures

CBD oil tinctures are applied sublingually or under the tongue using a dropper. The compound directly enters the bloodstream through the mucous membranes(26).

CBD Edibles

CBD edibles such as CBD supplements and gummies allow CBD to pass through the digestive tract before it enters the bloodstream.

CBD Vapes

Vaping or inhaling CBD is considered the quickest method of getting CBD into the system(27).

However, this method may cause potential health risks like lung disease, so caution should be exercised(28).

CBD’s efficacy may depend on an individual’s weight, metabolism, and diet.

Consulting with a physician or a healthcare professional may help you decide what kind of CBD products you may use for your medical issue. 

How to Choose a CBD Product for Leishmaniasis

Pertinent factors to consider when looking for the best CBD oil to fit your needs include the following: 

Types of CBD Extracts

Full-spectrum CBD oil has all the compounds of the cannabis plant like essential oils, cannabinoids, flavonoids, and terpenes(29).

Flavonoids are plant chemicals with antioxidant, anti-inflammatory, and antiviral benefits(30)

Full-spectrum CBD oil also has less than 0.3% tetrahydrocannabinol (THC) concentration.

THC is an active compound of cannabis plants with psychoactive properties or induces a euphoric high(31).

Combining all the mentioned compounds may produce an “entourage effect.” 

The entourage effect is defined as a phenomenon wherein the synthesis of different cannabis compounds may enhance their medicinal benefits(32)

A study from Frontiers in Plant Science suggested that the entourage effect in full-spectrum hemp extracts may produce better health benefits than pure CBD(33).

Meanwhile, broad-spectrum CBD oil contains similar cannabinoids and compounds as full-spectrum, with the exception of THC

Lastly, CBD isolates are a pure form of cannabidiol.  

Third-Party Lab Testing

Third-party labs should inspect CBD products for any contaminants like pesticides or heavy metals, which may cause detrimental effects to consumers. 

CBD brands should display their products’ COA (certificate of analysis) on their websites. Test results from third-party laboratories show the CBD product’s exact contents. 

Consumers should ensure that the COAs match the CBD product label before purchasing them. 

How Much CBD to Take for Leishmaniasis

The Food and Drug Administration or FDA has not authorized the use of CBD as a treatment for any medical condition(34). Thus, there is no standard CBD dosage for leishmaniasis. 

Research has suggested that humans are able to tolerate as much as 1,500mg of CBD every day(35).

Additionally, as a general rule, individuals without any CBD experience should start with low doses, slowly increasing the amount if they do not feel any significant side effects(36).

Nevertheless, talking to healthcare professionals with a background in cannabis use and dosing is highly recommended. These experts can advise on the proper CBD dosage for leishmaniasis. 

How Long Does CBD Take to Help With Leishmaniasis?

There are no clinical trials that determine how long it takes for a user to feel the effects of CBD for leishmaniasis.

CBD’s onset time may differ depending on factors such as the individual’s weight, CBD potency, and administration method. 

CBD tinctures, due to the compound’s direct entry into the bloodstream, may take 15 to 30 minutes before taking effect(37). CBD topicals also have the same onset time(38).

On the other hand, CBD edibles may have a slower onset time of 30 to 90 minutes(39)

CBD inhalation through the use of vape pens provides the quickest onset time. It generally takes 15 to 30 minutes before individuals feel the compound’s effects(40).

However, vaping may lead to severe pulmonary disease or lung irritation(41), so caution is advised.

How Long Will CBD Help With Leishmaniasis?

How long the effects of CBD remain in the system usually depends on how often you take CBD and how much of the compound you take. 

CBD, when applied topically, generally lasts in the body for approximately two to four hours(42)

Meanwhile, edibles like CBD gummies may linger in the body for six to eight hours. 

Risks and Side Effects of Using CBD for Leishmaniasis

There are no present studies on CBD’s potential risk factors and side effects when used for leishmaniasis.

However, taking the compound may lead to mild side effects like diarrhea, dry mouth, and fatigue(43).

CBD products may also come with a grapefruit warning, meaning they should not be taken with grapefruit. CBD may act as an inhibitor of the effects of the following drugs(44).

  • Antibiotics
  • Analgesics 
  • Blood pressure medications
  • Cholesterol medications

The interaction and inhibition of effects between grapefruit and the medication may vary in severity, depending on the amount of ingested grapefruit, the drugs’ composition, and the user’s health condition(45).

It is highly encouraged to confer with your physician before using any CBD product for leishmaniasis or any medical condition you may have. These professionals can give you advice on any possible drug-to-drug interactions. 

Legality of CBD

The only CBD-derived drug approved by the FDA is Epidiolex(46). This medication is prescribed by physicians to treat seizures associated with two rare forms of epilepsy in children, Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS). 

Recently, this medicine has been prescribed to manage seizures associated with tuberous sclerosis complex (TSC)(47).

The Farm Bill in 2018 has federally legalized the use of cannabis derivatives as long as they have less than 0.3% THC(48).

The bill has changed the definition of marijuana, reclassifying the leaves, buds, and seeds of a cannabis plant as hemp, as long as they contain very little THC.

Meanwhile, marijuana is naturally high in THC content. Marijuana used to alleviate symptoms caused by certain medical conditions is called medical marijuana or medical cannabis.

Make sure to verify state laws and legislations regarding the use of CBD to avoid any potential legal repercussions. 

Overview of Leishmaniasis

Leishmaniasis is a protozoan parasitic disease spread through the bite of infected sand flies. This disease has the most incidence in tropical and sub-tropical countries(49).

The CDC considers leishmaniasis as a neglected tropical disease or an NTD, a disease that has outbreaks in developing countries where medical care is limited(50)

The most typical forms of the disease are cutaneous leishmaniasis, which causes sores on the skin, and visceral leishmaniasis, which affects numerous internal organs like the liver, spleen, and bone marrow(51).

The incubation period of leishmaniasis ranges from two to eight weeks, and the symptoms may go away on their own if an infected individual has a healthy immune system(52).

Cutaneous Leishmaniasis Symptoms

Some people may be asymptomatic or have no symptoms or signs when infected. Other individuals may develop sores or lesions on their skin, which start as bumps and end up as ulcers(53)

Visceral Leishmaniasis Symptoms

Symptoms include weight loss, fever, and inflammation of the spleen and liver. Individuals may also have thrombocytopenia (low platelet count), anemia (low red blood cell), and leukopenia (low white blood cell)(54).

Alternative Treatment for Leishmaniasis 

Treatment for leishmaniasis depends on the Leishmania strain and the geographic location of the infection. 

The treatment plan is usually to accelerate the healing of the skin lesions and reduce the risk of the infection’s relapse.

Some medications include liposomal amphotericin B, ketoconazole, itraconazole, and fluconazole which are orally administered antifungal medications(55).

Product Frequently
Asked Questions

  • How can CBD help with leishmaniasis?

    Leishmaniasis is a parasitic infectious disease that causes painful lesions or open sores to appear all over the skin(56)

    Studies have shown that CBD may contain therapeutic benefits that may help manage pain, itchiness, and inflammation(57).

  • What evidence or research exists to say that CBD helps with leishmaniasis?

    A recent study has indicated the positive effects of applying topical CBD for skin disorders like psoriasis(58).  

    Psoriasis and leishmaniasis may cause skin lesions(59-60).

    Another study showed that CBD topicals have decreased pain and the formation of blisters and aided with faster wound healing of a rare skin disorder(61).

  • Is there any evidence that CBD can make leishmaniasis worse?

    There are no conclusive studies that state CBD use can make leishmaniasis worse.  

    Still, it is best to make an appointment with a healthcare professional experienced in cannabis use. Experts can give you pertinent information about possible risks, drug interactions, and allergic reactions.

  • Will CBD interact with any current medication I may be taking for leishmaniasis?

    In general, CBD is safe and does not pose a potential for abuse(62)

    However, a grapefruit warning in CBD products indicates that CBD may interact with other drugs and prevent those medications from getting absorbed by the body.

    It is best to ask for a doctor’s opinion before taking CBD alongside any medications for leishmaniasis.

  • Are there other treatments I should consider alongside CBD to help with leishmaniasis?

    Treating leishmaniasis usually involves promoting a quick healing time of the wounds and lessening the possibility of the infection returning. 

    Liposomal amphotericin B, ketoconazole, itraconazole, and fluconazole are some of the medications prescribed for leishmaniasis(63).

  • Can I fail a drug test if I use CBD for leishmaniasis?

    CBD is a non-psychoactive compound. Hence, it will not cause a euphoric high(64-65)

    However, CBD products contain trace amounts of THC, which may build up in the body if consumed regularly over time and potentially cause a positive drug test(66).

  • What is the CBD dosage for leishmaniasis?

    CBD, according to the FDA, is not a medical treatment for any diseases(67). Therefore, there is no set dosage when taking CBD for leishmaniasis. 

    Cannabidiol intake may be determined by stress levels, genetics, diet, exercise, and health conditions(68).

    Nonetheless, it is still best to talk to your physician about the optimal CBD dosage for your condition.

  • Does CBD for leishmaniasis get you high?

    No, CBD cannot make users high due to the compound not having any psychoactive properties(69).

  • Does CBD for leishmaniasis have any side effects?

    According to a review released by the World Health Organization (WHO), CBD is generally well tolerated by the human body, safe, and non-addictive(70)

    However, CBD may induce side effects like fatigue, sleepiness, lower appetite, diarrhea, dry mouth, and nausea(71).

    Before taking any CBD products, it is vital to consult your physician first. 

    For more information, read the disclaimers on CBD product labels. You can also research CBD through articles with open access and ebooks identified by their DOI (digital object identifier) number.


  1. Leishmaniasis
    https://www.cdc.gov/parasites/leishmaniasis/gen_info/faqs.html
  2. Ibid.
  3. Leishmaniasis
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202701/
  4. Ibid.
  5. Visceral leishmaniasis: A case report
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413930/
  6. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  7. The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412000/
  8. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  9. The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review of In Vivo Studies
    https://pubmed.ncbi.nlm.nih.gov/33998900/
  10. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  11. Ibid.
  12. Psoriasis
    https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840
  13. Leishmaniasis
    https://www.who.int/news-room/fact-sheets/detail/leishmaniasis
  14. Cannabinoid Delivery Systems for Pain and Inflammation Treatment
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222489/
  15. Ibid.
  16. Regulation of nausea and vomiting by cannabinoids
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165951/
  17. Visceral leishmaniasis: A case report
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413930/
  18. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  19. The Cannabis Terpenes
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763918/
  20. A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis
    https://www.frontiersin.org/articles/10.3389/fpsyt.2021.583211/full
  21. Syzygium cumini (L.) Skeels essential oil and its major constituent α-pinene exhibit anti-Leishmania activity through immunomodulation in vitro
    https://pubmed.ncbi.nlm.nih.gov/25460590/
  22. Ibid.
  23. Ibid.
  24. page 210 of Healing With CBD
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  25. Ibid.
  26. Healing with CBD page 205
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  27. Best way to take CBD
    https://www.projectcbd.org/guidance/best-way-take-cbd
  28. Can vaping damage your lungs? What we do (and don’t) know
    https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  29. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  30. Flavonoids as antioxidants
    https://pubmed.ncbi.nlm.nih.gov/10924197/
  31. Cannabidiol (CBD)
    https://www.ncbi.nlm.nih.gov/books/NBK556048/
  32. The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324885/
  33. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/
  34. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  35. Safety and side effects of cannabidiol, a Cannabis sativa constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  36. Healing with CBD. page. 227.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  37. Healing With CBD, page. 192
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  38. Healing With CBD, page. 193
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  39. Healing With CBD, page. 191
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  40. Best way to take CBD
    https://www.projectcbd.org/guidance/best-way-take-cbd
  41. Can vaping damage your lungs? What we do (and don’t) know
    https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  42. Healing With CBD, page. 193.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  43. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  44. Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  45. Grapefruit Juice and Some Drugs Don’t Mix
    https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix
  46. FDA Approves New Indication for Drug Containing an Active Ingredient Derived from Cannabis to Treat Seizures in Rare Genetic Disease
    https://www.fda.gov/news-events/press-announcements/fda-approves-new-indication-drug-containing-active-ingredient-derived-cannabis-treat-seizures-rare
  47. Ibid.
  48. New Congressional Farm Bill Legalizes Some Marijuana
    https://my.vanderbilt.edu/marijuanalaw/2018/12/new-congressional-farm-bill-legalizes-some-marijuana/
  49. Leishmaniasis
    https://www.who.int/news-room/fact-sheets/detail/leishmaniasis
  50. Leishmaniasis
    https://www.cdc.gov/parasites/leishmaniasis/gen_info/faqs.html
  51. Ibid.
  52. Leishmaniasis
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202701/
  53. Leishmaniasis
    https://www.who.int/news-room/fact-sheets/detail/leishmaniasis
  54. Ibid.
  55. Leishmaniasis
    https://www.cdc.gov/parasites/leishmaniasis/health_professionals/index.html
  56. Ibid.
  57. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  58. Ibid.
  59. Psoriasis
    https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840
  60. Leishmaniasis
    https://www.who.int/news-room/fact-sheets/detail/leishmaniasis
  61. Cannabinoid Delivery Systems for Pain and Inflammation Treatment
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222489/
  62. Cannabidiol (CBD), page 5.
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  63. Leishmaniasis
    https://www.cdc.gov/parasites/leishmaniasis/health_professionals/index.html
  64. Cannabidiol and Other Non-Psychoactive Cannabinoids for Prevention and Treatment of Gastrointestinal Disorders: Useful Nutraceuticals?
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246936/
  65. Cannabidiol (CBD)-what we know and what we don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  66. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  67. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  68. CBD dosing
    https://www.projectcbd.org/guidance/cbd-dosing
  69. Cannabidiol (CBD)-what we know and what we don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  70. Cannabidiol (CBD), page 5.
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  71. What are the benefits of CBD — and is it safe to use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
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