Best CBD Oil for CTE

Are you looking for natural alternative treatments to help with conditions caused by repeated head traumas? CBD Clinicals has all the information you need regarding CBD and its effect on CTE (chronic traumatic encephalopathy) if you want to manage your symptoms.

Rating
Highlights

Editor's Choice

Spruce 750mg Lab Grade CBD Oil

4.8 out of 5
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil

5.0 out of 5
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

Best High Potency

Spruce 2400mg Lab Grade CBD Oil

5.0 out of 5
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

Best Value

Avida Full Spectrum CBD Oil Tincture 500mg

4.6 out of 5
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

Best Value

cbdMD CBD Oil Tincture Natural 1500mg

4.7 out of 5
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

Best THC Free

CBDistillery THC Free CBD Oil Tinctures

4.4 out of 5
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg

4.4 out of 5
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil

4.6 out of 5
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

Best Flavor Range

Hemp Bombs 750mg CBD Oil

3.9 out of 5
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

Best Allergy Friendly

Royal CBD Full Spectrum CBD Oil

3.5 out of 5
  1. Has three flavors to choose from – Berry, Natural and Vanilla
  2. Vegan and Gluten-Free
  3. Superb customer service

Compare the Best CBD Oil for CTE in 2022

Product Potency Purity Customer Service Type Extraction Transparency Absorption
Spruce 2400mg Lab Grade CBD Oil
4.8 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Spruce 2400mg Lab Grade CBD Oil
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
5.0 out of 5
5.0 out of 5
Avida Full Spectrum CBD Oil Tincture 500mg
4.6 out of 5
5.0 out of 5
3.5 out of 5
3.0 out of 5
5.0 out of 5
4.5 out of 5
4.5 out of 5
5.0 out of 5
cbdMD CBD Oil Tincture Natural 1500mg
4.7 out of 5
5.0 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
CBDistillery THC Free CBD Oil Tinctures
4.4 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.5 out of 5
cbdMD CBD Oil Tincture Natural 750mg
4.4 out of 5
4.5 out of 5
3.5 out of 5
5.0 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
4.6 out of 5
2.5 out of 5
5.0 out of 5
5.0 out of 5
5.0 out of 5
4.5 out of 5
5.0 out of 5
5.0 out of 5
Hemp Bombs 750mg CBD Oil
3.9 out of 5
4.5 out of 5
3.5 out of 5
2.5 out of 5
3.5 out of 5
4.5 out of 5
5.0 out of 5
4.0 out of 5
Royal CBD Full Spectrum CBD Oil
3.5 out of 5
2.5 out of 5
3.5 out of 5
5.0 out of 5
5.0 out of 5
4.0 out of 5
1.0 out of 5
5.0 out of 5

Best CBD Oil for CTE

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score

4.8

CBDC Evaluation Table/Score
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Type

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Pros Cons

Mid-strength

No other flavors

Natural peppermint flavor

Made from 100% organic and natural ingredients

Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Pure CBD hemp

No other flavors

All natural

Approximately 300 drops total

Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score

5.0

CBDC Evaluation Table/Score
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Pros Cons

Extra Strength

Tastes bitter

No artificial flavoring or colors

No THC-free option

Made from 100% organic and natural ingredients

Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score

4.6

CBDC Evaluation Table/Score
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Light Spearmint flavor

No other flavor

Non-THC, Non-detected in drug test

Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score

4.7

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

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Pros Cons

Various delicious flavors to choose from

cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options

Has vegan, organic, and gluten-free ingredients

Free shipping for this particular product within USA

World-class customer service team

Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score

4.4

CBDC Evaluation Table/Score
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Type

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Pros Cons

60-Day Satisfaction Guarantee

Dropper is a bit shaky

Various strengths

Oil extracted from aerial plant parts of US grown industrial hemp

Sourced from non-GMO industrial hemp grown in the USA through natural farming practices

Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score

4.6

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

Extraction

Absorption

Transparency

Pros Cons

Pure CBD hemp

No other flavors

All natural

A bit pricey compared to competitors

Approximately 100 drops total

Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score

4.4

CBDC Evaluation Table/Score
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Type

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Pros Cons

Vegan and Gluten free

Does not ship internationally

Has a third-party lab test

Wide variety of CBD strengths and sizes

Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score

3.9

CBDC Evaluation Table/Score
Potency

Purity

Customer Service

Type

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Transparency

Pros Cons

Wide variety of flavors

Incomplete information about the product

Lab test results are complete

Does not ship to all international countries

30-day money-back guarantee

Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

10. Royal CBD Full Spectrum CBD Oil
cbdc overall score

3.7

CBDC Evaluation Table/Score
Potency

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Customer Service

Type

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Pros Cons

Rich in phytochemicals including CBD, CBC, CBG, and a variety of flavorful terpenes

Shipping not specified on website

More flavors to choose from

3rd party lab result is currently not available on website

Extracts contain a whole array of cannabinoids and terpenes from the hemp plant — rather than pure CBD isolate

Overview

Excellent products and superb customer service. Whenever you want to ask them about the dosage, recommended consumption methods, or which CBD oil will work best for you, just give them a call, send them a message, or get in touch with their social media channels. They won’t leave you with any unanswered questions.

How CBD May Help With CTE

Cannabidiol, popularly known as CBD, is a phytocannabinoid (plant-based cannabinoid) found in the cannabis plant

Unlike THC (tetrahydrocannabinol), the primary psychoactive compound of cannabis, CBD does not cause a euphoric high(1)

CBD’s neuroprotective potential, based on its purported antioxidant and anti-inflammatory properties, is of particular interest for numerous neurodegenerative disorders(2). CTE (chronic traumatic encephalopathy) is an example of a neurodegenerative condition.

Neurodegenerative disorders are incurable conditions resulting in the death of nerve cells. 

CTE is a cumulative brain disease caused by repeated head traumas or mild TBI (traumatic brain injury)(3).  

CBD accounts for up to 40% of the cannabis plant’s extract that binds to various physiological targets of the ECS (endocannabinoid system)(4).

The ECS is responsible for maintaining bodily homeostasis or balance. It comprises endogenous cannabinoids (endocannabinoids), enzymes, and cannabinoid receptors (CB1 and CB2). 

CB1 receptors present within the pain pathways of the central nervous system may affect CBD-induced analgesia (loss of pain perception) and anxiolysis (anxiety relief)(5)

Pain and stress are common symptoms of CTE(6). In addition, one of the risk factors for developing anxiety disorder is stress buildup(7). CBD may help with pain(8) and anxiety(9).

An animal study demonstrated that in a rat’s brain, the neuroprotective effect exerted by the CB1 receptor against excitotoxicity is restricted to the CB1 receptor population situated on glutamatergic terminals(10)

Excitotoxicity refers to the harmful actions of neurotransmitters, mainly glutamate. Glutamate is an amino acid abundant in the brain with excitatory effects on nerve cells.

It is believed that the prolonged activation of glutamate receptors begins a cascade of neurotoxicity that leads to neurodegeneration and cell death(11).

 Neurodegeneration, a progressive loss of neurons’ functions, is common in neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease

A research article from Neuropsychopharmacology mentioned that CBD may modulate excitatory glutamate(12). In addition, CBD is believed to have anti-inflammatory and neuroprotective activity(13)

Chronic inflammation has been observed in CTE, which is thought to worsen the neurodegenerative process(14).

Although limited studies exist examining the effect of CBD hemp oil on CTE, its putative usefulness for inflammation and neurodegeneration associated with brain conditions like CTE is plausible considering CBD’s pharmacology. 

Still, more research is warranted to elucidate how CBD may help with CTE

Benefits of Using CBD for CTE  

A study from Frontiers in Integrative Neuroscience mentioned that cannabis, particularly chemovars with CBD and THC, may help manage CTE symptoms like headache, insomnia, dizziness, nausea, agitation, psychotic symptoms, and substance abuse(15)

Chemovar refers to the breakdown of a plant specifies in proportion to its chemical composition. 

An animal study from the Journal of Neurotrauma suggested that traumatic brain injury may affect neurogenesis in the adult mouse hippocampus(16)

Neurogenesis refers to the birth of new brain cells and neurons

CBD has neuroprotective potential(17). Furthermore, research suggests that understanding how CBD may promote adult neurogenesis in rodents may shed light regarding translational therapeutic strategies that may help with certain psychiatric conditions(18)

It is worth noting that CTE has been associated with psychiatric symptoms, such as aggression, suicidal behavior, and depression(19).  

Although CTE symptoms do not develop immediately after a head injury, experts believe they may progress over the years after repeated brain trauma(20).

In a sample of 266 deceased former NFL and amateur football players, the Boston University School of Medicine researchers suggested that each year of play may increase the odds of developing CTE by 30%(21)

Interestingly, the experts hypothesized that other potential variables like the position played, number of concussions, age by which players started tackle football, race, co-morbid disease, and participation in other contact sports are not associated with CTE risk or severity. 

Concussions are traumatic brain injuries (TBI) that affect brain function.  

Research suggests that post-injury oxidative stress is a key factor that links traumatic brain injury to an increased risk of neurodegeneration(22)

Oxidative stress refers to an imbalance between antioxidants and free radicals. 

CBD may affect redox balance by modifying the activity and level of oxidants and antioxidants(23). The compound may also interrupt free radical chain reactions by transforming free radicals into less active forms. 

Meanwhile, individuals who want to manage their CTE symptoms may find pain management therapy helpful(24). Some studies suggest that CBD may likely treat chronic pain(25). Still, CBD should not be used indiscriminately

It is also worth noting that CBD is not a cureall. Hence, the compound cannot heal brain damage or neural impairment

More importantly, although the studies mentioned seem promising, they are inconclusive, and some were conducted on animal models. However, researchers who want to perform clinical trials to elucidate the benefits of CBD for CTE may find the results helpful. 

How to Take CBD for CTE

There are various ways to take CBD for CTE. Below are common administration methods to benefit from the effects of CBD

  • Inhalation (vaping or smoking CBD using vape pens)
  • Ingestion (taking CBD edibles like gummies or capsules) 
  • Sublingual route (holding CBD tinctures under your tongue) 
  • Topical absorption (applying CBD creams or lotions to the skin for localized relief) 

Remember that these routes of administration have their pros and cons. 

For instance, inhaling CBD using vape pens is the fastest delivery method(26).

The onset time of CBD via the inhalation route is between 2 and 15 minutes, and its effect usually lasts from 2 to 4 hours(27)

Nevertheless, the CDC (Centers for Disease Control and Prevention) and the FDA (Food and Drug Administration) warn people against the use of THC-containing e-cigarettes or any vaping products, mainly from informal sources(28)

Most lung injury cases in the U.S. are associated with vaping(29)

Meanwhile, the sublingual method also provides rapid effects without exposing the lungs to tar and heat(30)

The capillaries under the tongue and within the mouth absorb CBD into the bloodstream before the compound is swallowed(31)

 If you choose to take CBD under the tongue, you will feel its effects within 15 to 30 minutes, and they may last from 2 to 4 hours(32)

CBD Dosage for CTE

The FDA has not approved cannabidiol as a medical treatment for CTE. Therefore, there is no standard CBD dosage for the disorder. 

However, it is believed that microdoses of CBD, in the range of 0.5mg to 20mg daily, may help with headaches and nausea(33)

Headache and nausea are among the common symptoms of CTE(34).  

Still, it is best to talk with a doctor versed in cannabis use to determine the accurate dose for your specific condition. 

How Long Does CBD Take to Help With CTE?

How long CBD takes to help with CTE usually depends on several factors, including the administration route, individual body weight, the type of CBD, and potency.

For instance, if you take CBD via the inhalation route, you will feel its effects within 2 to 15 minutes(35). However, vaping or smoking may damage your lungs(36).

On the other hand, the onset time of CBD via the sublingual route is between 15 and 30 minutes(37).  

How Long Will CBD Help With CTE?

How long CBD’s effects will last after the compound starts to help depends on its bioavailability and half-life.

Bioavailability is the extent to which a particular substance becomes entirely available to its intended biological destinations. 

Meanwhile, half-life refers to the length of time needed for the concentration of a specific drug to decrease by 50% of its starting dose. 

About 94% to 97% of a substance will have been eliminated after four to five half-lives(38)

A systematic review from Frontiers in Pharmacology mentioned that CBD’s bioavailability following smoking is 31%, with a half-life of 31 hours(39)

On the other hand, CBD’s bioavailability via the sublingual route is between 6% and 20%(40). Furthermore, CBD is reported to have a half-life between 1.4 and 10.9 hours following oromucosal spray(41)

How to Choose the Right CBD for CTE

There are various CBD brands in the market promising to offer the best CBD oil for conditions like CTE. Here are a few pertinent factors to consider that may help you sort through products to find the right CBD product for you:

  • CBD Extracts

A full-spectrum CBD product contains all compounds of the cannabis plant, including less than 0.3% of THC. Additionally, this CBD variant is known to produce the entourage effect due to the presence of all cannabis compounds. 

The entourage effect is a concept where the biologically active compounds of cannabis work better when administered together. 

Meanwhile, broad-spectrum CBD oil also contains all of the natural compounds of cannabis except for THC. Lastly, CBD isolates are made of pure cannabidiol

  • Ingredients 

Make sure to choose CBD formats made with natural, organic ingredients or non-GMO products. 

  • Extraction Method

Carbon dioxide, ethanol, or solvent extraction is preferred to create a safe CBD product(42). Extraction techniques utilizing hexane or butane may leave harmful residues, like pesticides.

  • Third-Party Lab Testing

Make sure that the CBD brand you choose enlists the services of a third-party laboratory to test all of its items. This lab must provide up-to-date COAs (certificates of analysis) containing all the vital details of a particular CBD product, like its potency and consistency.  

Is It Safe to Use CBD if You Have CTE?

According to the WHO (World Health Organization), cannabidiol is generally well tolerated in humans and animals alike. The compound also has a good safety profile(43)

Additionally, a review from Current Drug Safety reported that the chronic use and high doses of CBD, up to 1,500mg per day, are well tolerated in humans(44)

Still, it is best that you consult a doctor versed in cannabis use, primarily if you are using CBD for CTE for the first time. 

Risks and Side Effects of CBD Usage for CTE

CBD may also carry some risks and produce minor side effects, including(45)

  • Fatigue 
  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness 

Currently, no disease-modifying treatments are available for CTE. However, various medications may help improve cognitive function. 

For instance, selective serotonin reuptake inhibitors or SSRIs may help manage different behavioral and cognitive problems(46)

However, if you want to use SSRIs simultaneously with CBD, make sure to consult your healthcare provider. 

Cannabidiol is a potent inhibitor of CYP2D6, which metabolizes various antidepressants. Hence, the non-psychoactive compound may increase serum concentrations of antipsychotics, opioids, and SSRIs(47)

CYP2D6 is an enzyme primarily expressed in the liver.  

Legality of CBD

The U.S. Congress ratified the 2018 Farm Bill, legalizing the commercial use of industrial hemp and products obtained from hemp plants(48)

The Farm Bill states that Cannabis sativa L. and other derivatives of cannabis with no more than 0.3% THC content on a dry weight basis are deemed legal under federal law(49).

Some states have passed laws allowing the use of recreational and medical marijuana. 

In Texas, the local government passed laws in June 2019, establishing a state industrial hemp program(50)

Under House Bill 1325, the Texas Department of State Health Services is in charge of issuing licenses for people who want to manufacture or sell consumable hemp-derived products in the Lone Star State. 

Colorado is another state that authorizes recreational and medical marijuana use. The local government decriminalized the use of marijuana by passing Amendment 64 to the Colorado Constitution in November 2012(51).   

You may check government reports and journals online using a digital object identifier (DOI) to know more about various state laws. 

Still, remember that even if a specific state law indicates that CBD is legal, the only FDA-approved CBD drug is Epidiolex, used to treat rare and severe forms of epilepsy.

Product Frequently
Asked Questions

  • How can CBD help with CTE?

    CBD has purported neuroprotective effects(52). A study mentioned that the potential neuroprotective benefits of phytocannabinoids, particularly CBD, may help with CTE prevention(53).

  • What evidence or research exists to say that CBD helps with CTE?

    It is believed that cannabis, particularly chemovars with CBD and THC, may help manage CTE symptoms like headache(54).

  • Is there any evidence that CBD can make CTE worse?

    No evidence suggests that CBD can make CTE worse. Still, CBD may induce minor side effects like fatigue(55).

  • Will CBD interact with any current medication I may be taking for CTE?

    CBD is not a biologically inert compound. Therefore, it can potentially interact with other medications(56)

    For instance, SSRIs and antipsychotic drugs may help with CTE and its associated symptoms(57). However, CYP2D6, an enzyme primarily expressed in the liver, metabolizes both substances. 

    Since CBD is a potent inhibitor of CYP2D6, the compound may increase the serum concentration of these drugs(58)

  • Are there other treatments I should consider alongside CBD to help with CTE?

    Some individuals with CTE experience mood disorders, such as depression, suicidal thoughts, and emotional instability(59)

    If you have a mood disorder, your physician may prescribe antidepressants for treatment(60). However, be sure to consult your healthcare provider before you use CBD alongside any other medications to help with CTE.

    As previously mentioned, CBD may interact with antidepressants(61).

  • Can I fail a drug test if I use CBD for CTE?

    CBD does not induce a euphoric effect(62). However, a full-spectrum CBD product has small amounts of THC that may build up in the body when taken regularly in a span of four to six days(63)

    An increased THC level in the bloodstream may result in a positive drug test.  

  • What is the CBD dosage for CTE?

    Microdoses of CBD, in the range of 0.5mg to 20mg daily, may help with headaches and nausea(64). Headache and nausea are common symptoms of CTE(65)

    Still, it is best to talk with a doctor experienced in recommending CBD before using the compound to help with CTE.


  1. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476 
  2. Cannabidiol for Neurodegenerative Disorders: Important New Clinical Applications for This Phytocannabinoid?
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579248/
  3. Chronic Traumatic Encephalopathy: A Neurodegenerative Consequence of Repetitive Traumatic Brain Injury
    https://pubmed.ncbi.nlm.nih.gov/25714864/
  4. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  5. Ibid.
  6. Chronic Traumatic Encephalopathy (CTE)
    https://my.clevelandclinic.org/health/diseases/17686-chronic-traumatic-encephalopathy-cte
  7. Anxiety disorders
    https://www.mayoclinic.org/diseases-conditions/anxiety/symptoms-causes/syc-20350961
  8. Research shows pain-relieving effects of CBD
    https://www.sciencedaily.com/releases/2021/04/210423130221.htm
  9. Cannabidiol as a Potential Treatment for Anxiety Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
  10. A Restricted Population of CB1 Cannabinoid Receptors With Neuroprotective Activity
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050577/
  11. Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases
    https://www.frontiersin.org/articles/10.3389/fncel.2020.00090/full
  12. Effects of Cannabidiol on Brain Excitation and Inhibition Systems; a Randomised Placebo-Controlled Single Dose Trial During Magnetic Resonance Spectroscopy in Adults With and Without Autism Spectrum Disorder
    https://www.nature.com/articles/s41386-019-0333-8
  13. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  14. Pathological Correlations Between Traumatic Brain Injury and Chronic Neurodegenerative Diseases
    https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-017-0088-2
  15. Cannabis Therapeutics and the Future of Neurology
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
  16. Traumatic Brain Injury Severity Affects Neurogenesis in Adult Mouse Hippocampus
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841001/
  17. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  18. The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders
    https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00109/full
  19. Behavioral Health Symptoms Associated With Chronic Traumatic Encephalopathy: A Critical Review of the Literature and Recommendations for Treatment and Research
    https://pubmed.ncbi.nlm.nih.gov/26037854/
  20. Chronic Traumatic Encephalopathy
    https://www.mayoclinic.org/diseases-conditions/chronic-traumatic-encephalopathy/symptoms-causes/syc-20370921
  21. CTE Risk, Severity Increases With Years Playing American Football
    https://www.sciencedaily.com/releases/2019/10/191007115239.htm
  22. Pathological Correlations Between Traumatic Brain Injury and Chronic Neurodegenerative Diseases
    https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-017-0088-2
  23. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  24. Chronic Traumatic Encephalopathy (CTE)
    https://my.clevelandclinic.org/health/diseases/17686-chronic-traumatic-encephalopathy-cte
  25. A Balanced Approach for Cannabidiol Use in Chronic Pain
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204604/
  26. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  27. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  28. Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products
    https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html
  29. Ibid.
  30. CBD: A Patient’s Guide to Medicinal Cannabis, page 105.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  31. Healing With CBD, page 207.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  32. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  33. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  34. Cannabis Therapeutics and the Future of Neurology
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
  35. Healing With CBD, page 190.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  36. Is It Safe to Vape CBD?
    https://www.consumerreports.org/cbd/is-it-safe-to-vape-cbd/
  37. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  38. Half-Life
    https://www.ncbi.nlm.nih.gov/books/NBK554498/
  39. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  40. Healing With CBD, page 192.
    https://drive.google.com/file/d/1AGlxnhS2SoFeOXEuysv75bd_C9pEnwsU/view
  41. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275223/
  42. Cannabidiol Primer for Healthcare Professionals
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340472/
  43. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  44. Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
    https://pubmed.ncbi.nlm.nih.gov/22129319/
  45. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  46. A Healthcare Provider’s Guide to Chronic Traumatic Encephalopathy (CTE), page 3.
    https://memory.ucsf.edu/sites/memory.ucsf.edu/files/wysiwyg/UCSF_CTE_Providers_7-13-17.pdf
  47. Medical Cannabis: Adverse Effects and Drug Interactions, page 11.
    https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  48. H.R.2 – Agriculture Improvement Act of 2018
    https://www.congress.gov/bill/115th-congress/house-bill/2/text
  49. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD)
    https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  50. Cannabis and the Law
    https://guides.sll.texas.gov/cannabis/cbd
  51. Legal Marijuana Use in Colorado
    https://cannabis.colorado.gov/legal-marijuana-use-in-colorado
  52. Cannabidiol
    https://pubchem.ncbi.nlm.nih.gov/compound/Cannabidiol
  53. Cannabis Therapeutics and the Future of Neurology
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
  54. Ibid. 
  55. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  56. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/
  57. A Healthcare Provider’s Guide to Chronic Traumatic Encephalopathy (CTE), page 3.
    https://memory.ucsf.edu/sites/memory.ucsf.edu/files/wysiwyg/UCSF_CTE_Providers_7-13-17.pdf
  58. Medical Cannabis: Adverse Effects & Drug Interactions
    https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  59. Chronic Traumatic Encephalopathy
    https://www.mayoclinic.org/diseases-conditions/chronic-traumatic-encephalopathy/symptoms-causes/syc-20370921
  60. Mood Disorders
    https://my.clevelandclinic.org/health/diseases/17843-mood-disorders
  61. Medical Cannabis: Adverse Effects & Drug Interactions
    https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  62. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  63. Can You Take CBD and Pass a Drug Test?
    https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/
  64. CBD: A Patient’s Guide to Medicinal Cannabis, page 129.
    https://drive.google.com/file/d/1MILU_6ZjYkII-XMUPHLFPiPQbrz__5Sh/view
  65. Cannabis Therapeutics and the Future of Neurology
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/

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